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Raymond Pranata
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Editorial Office: Heart House, Jalan Katalia Raya No. 5, Kota Bambu Utara West Jakarta, 11430 - Indonesia Telephone: +62 21 5681149, Fax: +62 21 5684220 Email: ijc@inaheart.org
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INDONESIA
Indonesian Journal of Cardiology
Published by Indonesian Heart Association
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Arjuna Subject : Kedokteran - Cardiology and Cardiovascular Medicine
Articles 14 Documents
 1   2 
Search results for , issue "Vol. 38, No. 2 April-June 2017" : 14 Documents clear
What Is the Cause of Non-responders in CRT and How to Identify It? Yamin, Muhammad
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.728

Abstract

No Abstract
Hypolipidemic Effect and Antioxidant Activity of Tamarind Leaves Extract in Hypercholesterol-Fed Rats Aprilia, Citra Ayu; Ninditasari, Ghina; BR, Djoko Walujo
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.730

Abstract

Background: Higher cost and side effects made of some anticholesterol drugs usedin long time are the reasons why some people change to herbal therapies. Tamarind(Tamarindus indica) leaves is one of the herbal therapies. This research aims to determinehypolipidemic effect and antioxidant activity of extract of tamarind leaves (ETL).Methods: We used 25 rats as samples, divided into five groups of negative control(CMC 0.5%), positive control (Ezetimibe 1.26 g/kgBW)), first, second and third doseof ETL consequently are 0.93, 1.86 and 3.73 g/kgBW.Results: Paired-samples T-test showed ETL significantly decreased total cholesterol(TC), triglyceride (TG) level, and high-density lipoprotein cholesterol (HDL-C) levelsignificantly increased compared with negative control groups (p≤0.05). Low-densitylipoprotein cholesterol (LDL-C) level had significant difference only at second dose ofETL (p<0.05). Furthermore, the data’s difference between pre- and post-interventionwere analyzed with one-way ANOVA test in TC, TG, and HDL-C level, ETL had asignificant difference (p≤0.05), while there was no significant difference in LDL -Cbetween groups (p>0.05). Data were also analyzed by Post Hoc test. TC, TG, andHDL-C level had a significant difference between all variance ETL’s doses and positivecontrol compared with negative control group (p≤0.05). For antioxidant activity, ETLexhibited the significant reduction in the levels of malondialdehyde (MDA) by pairedsamplesT-test (p≤0.05) but there was no significant difference in both of MDA andsuperoxide dismutase (SOD) level (p>0.05) analyzed by One-way ANO VA test.Conclusion: All variant of ETL’s doses have hypolipidemic effect and antioxidant activity.ETL also has similar effect with Ezetimibe. Saponin, flavonoid, epicatechin, tanin, andpolyphenol that is contained likely contribute to these pharmacologic effects.
Shock Index as Simple Clinical Independent Predictor of In-hospital MACEs in NSTEMI Patients Presenting with Heart Failure Handayani, Ahmad; Kaban, Kartika; Nasri, Marwan; Mukhtar, Zulfikri; Siregar, Abdullah Afif
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.731

Abstract

Background: Identification of Non-ST Elevation Myocardial Infarction (NSTEMI) patientsat higher risk of in-hospital complications is very important. Such identification will givecrucial information in determining treatment strategy especially for those come with heartfailure. One of the simple predictor for short term prognosis in acute coronary syndromeis shock index (SI), which is the ratio of heart rate over systolic blood pressure on admission.There had not been any study conducted to evaluate the use of SI in NSTEMI patientscome with heart failure. The aim of this study is to evaluate the SI compared with otherroutine clinical and laboratory examination as a predictor of in-hospital major adversecardiac events (MACEs) in NSTEMI patients presenting with heart failure.Methods: We performed a retrospective analysis of NSTEMI patients with heart failureadmitted to Haji Adam Malik General Hospital in Medan from January 2014 until July 2015.SI was calculated as the ratio of heart rate over systolic blood pressure on presentation.Patients presenting with cardiogenic shock were excluded.Results: There were 55 patients eligible in this study. In-hospital MACEs was found in 24patients (44%) compared with 31 patients (56%) without in-hospital MACEs. Patientswith in-hospital MACEs were older (60.6±10.8 vs. 57.2±7.9, p=0.178), had less historyof dyslipidemia [8(33%) vs. 19 (61%), p=0.032], faster heart rate (111.4±35.8 vs.96.5±24.3, p=0.032], higher GRACE score [139(98-187) vs. 120 (91-148); p=0.001],and higher SI [0.83(0.57-1.5) vs. 0.67 (0.38-1.27), p=0.013). SI >0.8 was the only independentpredictor of MACEs in NSTEMI patients presenting with heart failure (OR=4.3,CI=1.247-14.328, p=0.048).Conclusion: Beyond other routine examinations, SI is the only independent predictor ofin-hospital MACEs in NSTEMI patients presenting with heart failure.
Pemberian Agen Vasoaktif Berdasarkan Hemodinamik pada Syok Kardiogenik Alsagaff, Muhammad Yusuf; Djihan, Laily
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.732

Abstract

Cardiogenic shock is a life-threatening emergency that occurs frequently with acutemyocardial infarction (AMI) and the mortality remains over 50% in most studies. Despitesuccessful revascularization, cardiovascular failure leading to multiple organ failure mayoccur. Therapy with vasoactive agents should be initiated to restore adequate arterialpressure and organ perfusion in patients with shock. Recent analysis suggests that systemicinflammatory response syndrome (SIRS) is an important component of the hemodynamicinstability in cardiogenic shock. Inflammation through the nitric oxide (NO) pathway leadingto decrease in vascular resistance and these patients may necessitate supplementalvasopressor therapy. A subanalysis of a prospective randomized trial suggested that norepinephrine(NE) may be preferred over dopamine in patients with cardiogenic shock,while dobutamine is the inotrope of choice. We present a case of a shock cardiogenicand a review of a therapeutic scheme for the pharmacological treatment of patients incardiogenic shock.
Comparison of Roles between Alcohol Ablation and Surgical Myectomy in Hypertrophic Cardiomyopathy Kusuma, Nico; Pranata, Raymond; Vania, Rachel; Siswanto, Bambang Budi
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.733

Abstract

Hypertrophic cardiomyopathy is a genetic myocardial disease that may extend to leftventricular outflow tract obstruction. Alcohol septal ablation (ASA) is preferred for itsnon-surgical, agreed as the safest way for advanced aged, or those with high risk for surgicalprocedure or comorbidities. On the other hand, surgical myectomy (SM) remainsas gold standard, established to be the most consistent to achieve optimal hemodynamicand spare longevity, regardless selective use. This article reviews the advantages anddisadvantages between SM and ASA ablation from its outcome, mortality, pre- and postprocedural,and patient’s profile selection.
Diagnostic Value of Left Ventricular Early Inflow-Outflow Index in Determining Severity of Mitral Regurgitation Yulia, Vera; Yanni, Mefri; Hariyanto, Didik
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.729

Abstract

Background: Determining severity of mitral regurgitation (MR) is very important, asit is related with prognosis and management of the disease. Currently, there is no goldstandard exists for quantification of MR severity using echocardiography. AmericanSociety of Echocardiography (ASE) guidelines recommend several parameters basedon integrative criteria using color and spectral Doppler and anatomic measurement.Left Ventricular Early Inflow Outflow Index (LVEIO Index) was proposed as one parameterto assess the severity of MR by omitting geometric error from regurgitantvolume method. Thus, LVEIO index offers a simple, easy and accurate measurementin determining severity of MR.Methods: This study was a diagnostic test research with cross-sectional design. Thesubjects were all patients with organic mitral regurgitation who underwent echocardiographyexamination to measure severity of MR using the LVEIO index as well asother parameters measurements based on parameters of ASE guidelines. Diagnostictest was used to determine the sensitivity, specificity, positive predictive value, negativepredictive value and accuracy of LVEIO index.Results: Of 49 patients in this study, 23 of them have severe MR and 26 are non-severeMR patients. The proportion of gender between two groups almost similar with an agerange from 56 to 61 years and the most common etiology finding was degenerative MR.Echocardiography examination showed the ejection fraction in severe MR was 63±4.2%and 64±3.9% in non-severe MR. The value of LAVI, MPAP, E-wave, VC, EROA andLVEIO index increased parallel with severity of MR (LAVI; 67±18.2 vs. 40±14.2 ml/m2,MPAP; 28±12.8 vs. 20±12.6 mmHg, E-wave 1.5±0.3 vs. 1±0.2 m/s, VC 0.8±0.3 vs.0.5±0.1 cm, EROA 0.4±0.1 vs 0,2±0,1cm2, LVEIO 9±2,4 vs. 5±1,8). The sensitivity,specificity, and accuracy of LVEIO index for diagnosis of severe MR were 86%, 84%,and 89%, respectively.Conclusion: LVEIO can be proposed as a relatively simple, easy and accurate methodin determining severity of MR.
Pedoman Tatalaksana Takiaritmia Supraventrikular (TaSuV) Raharjo, Sunu Budhi; Yuniadi, Yoga; Muzakkir, Muzakkir; Yansen, Ignatius; Munawar, Dian Andina; Hermanto, Dony Yugo
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.734

Abstract

No abstract
What Is the Cause of Non-responders in CRT and How to Identify It? Muhammad Yamin
Jurnal Kardiologi Indonesia Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i2.728

Abstract

No Abstract
Diagnostic Value of Left Ventricular Early Inflow-Outflow Index in Determining Severity of Mitral Regurgitation Vera Yulia; Mefri Yanni; Didik Hariyanto
Jurnal Kardiologi Indonesia Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i2.729

Abstract

Background: Determining severity of mitral regurgitation (MR) is very important, asit is related with prognosis and management of the disease. Currently, there is no goldstandard exists for quantification of MR severity using echocardiography. AmericanSociety of Echocardiography (ASE) guidelines recommend several parameters basedon integrative criteria using color and spectral Doppler and anatomic measurement.Left Ventricular Early Inflow Outflow Index (LVEIO Index) was proposed as one parameterto assess the severity of MR by omitting geometric error from regurgitantvolume method. Thus, LVEIO index offers a simple, easy and accurate measurementin determining severity of MR.Methods: This study was a diagnostic test research with cross-sectional design. Thesubjects were all patients with organic mitral regurgitation who underwent echocardiographyexamination to measure severity of MR using the LVEIO index as well asother parameters measurements based on parameters of ASE guidelines. Diagnostictest was used to determine the sensitivity, specificity, positive predictive value, negativepredictive value and accuracy of LVEIO index.Results: Of 49 patients in this study, 23 of them have severe MR and 26 are non-severeMR patients. The proportion of gender between two groups almost similar with an agerange from 56 to 61 years and the most common etiology finding was degenerative MR.Echocardiography examination showed the ejection fraction in severe MR was 63±4.2%and 64±3.9% in non-severe MR. The value of LAVI, MPAP, E-wave, VC, EROA andLVEIO index increased parallel with severity of MR (LAVI; 67±18.2 vs. 40±14.2 ml/m2,MPAP; 28±12.8 vs. 20±12.6 mmHg, E-wave 1.5±0.3 vs. 1±0.2 m/s, VC 0.8±0.3 vs.0.5±0.1 cm, EROA 0.4±0.1 vs 0,2±0,1cm2, LVEIO 9±2,4 vs. 5±1,8). The sensitivity,specificity, and accuracy of LVEIO index for diagnosis of severe MR were 86%, 84%,and 89%, respectively.Conclusion: LVEIO can be proposed as a relatively simple, easy and accurate methodin determining severity of MR.
Hypolipidemic Effect and Antioxidant Activity of Tamarind Leaves Extract in Hypercholesterol-Fed Rats Citra Ayu Aprilia; Ghina Ninditasari; Djoko Walujo BR
Jurnal Kardiologi Indonesia Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i2.730

Abstract

Background: Higher cost and side effects made of some anticholesterol drugs usedin long time are the reasons why some people change to herbal therapies. Tamarind(Tamarindus indica) leaves is one of the herbal therapies. This research aims to determinehypolipidemic effect and antioxidant activity of extract of tamarind leaves (ETL).Methods: We used 25 rats as samples, divided into five groups of negative control(CMC 0.5%), positive control (Ezetimibe 1.26 g/kgBW)), first, second and third doseof ETL consequently are 0.93, 1.86 and 3.73 g/kgBW.Results: Paired-samples T-test showed ETL significantly decreased total cholesterol(TC), triglyceride (TG) level, and high-density lipoprotein cholesterol (HDL-C) levelsignificantly increased compared with negative control groups (p≤0.05). Low-densitylipoprotein cholesterol (LDL-C) level had significant difference only at second dose ofETL (p<0.05). Furthermore, the data’s difference between pre- and post-interventionwere analyzed with one-way ANOVA test in TC, TG, and HDL-C level, ETL had asignificant difference (p≤0.05), while there was no significant difference in LDL -Cbetween groups (p>0.05). Data were also analyzed by Post Hoc test. TC, TG, andHDL-C level had a significant difference between all variance ETL’s doses and positivecontrol compared with negative control group (p≤0.05). For antioxidant activity, ETLexhibited the significant reduction in the levels of malondialdehyde (MDA) by pairedsamplesT-test (p≤0.05) but there was no significant difference in both of MDA andsuperoxide dismutase (SOD) level (p>0.05) analyzed by One-way ANO VA test.Conclusion: All variant of ETL’s doses have hypolipidemic effect and antioxidant activity.ETL also has similar effect with Ezetimibe. Saponin, flavonoid, epicatechin, tanin, andpolyphenol that is contained likely contribute to these pharmacologic effects.

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