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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 7 Documents
 1 
Search results for , issue " Volume. 33. No. 4, October 2009" : 7 Documents clear
Profile of pregnant women with tuberculosis at the tuberculosis policlinic of the eradication of tuberculosis, Tuberculosis Foundation, Baladewa Central Jakarta Maharani, Laksmi
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know profile of pregnant women with tuberculosis at PPTI Baladewa polyclinic Jakarta, to evaluate impacts of tuberculosis medicinal treatment on pregnancy and to know the obstacles of pregnant women to look for tuberculosis treatment. Methods: Subjects were all pregnant women with tuberculosis and received tuberculosis treatment at polyclinic of PPTI Baladewa from January 2006 - December 2007. We reviewed medical record and did home visitation to fill questioners. Results: All subjects were in reproductive age and most of all were low socio-economic group. Pulmonary tuberculosis was found in 88.2% cases and Extrapulmonary tuberculosis in 11.8% cases. We found 29.4% relapse cases and 11.8% multi-drug resistance. Sputum examination with a smear positive for acid fast-bacillus was found in 52.9% cases. There was abnormality for all chest x-rays. The third most frequently symptoms were cough more than two weeks (88.2%), weight loss (88.2%) and anorexia (82.4%). Average time for the patients to look for treatment was 50.71 ± 31.2 days. The patients need more time because most of the symptoms are also present in pregnancy, the patients know absolutely nothing about TB and healthcare provider didn’t examine carefully. Treatment for the patients was given immediately without considering the gestational age. Conclusion: No harmful effect was observed for neonates even if the drugs were given in the first trimester of pregnancy. [Indones J Obstet Gynecol 2009;33-4:210-5] Keywords: profile, pregnancy, tuberculosis
Two Designated Pathways of Ovarian Cancer and the Crucial Implications to the Treatment Putri, Henny M.A. Rachmasari
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To review the two designated pathways of ovarian cancer and their implications to the management of ovarian cancer. Method: Literature review Result: A proposed carcinogenesis of ovarian cancer has been developed based on a long history of pathological and molecular genetic findings. It divides ovarian cancer as having designated type I or type II pathway. Type I pathway involves ovarian carcinomas with low-grade serous subtype, mucinous, clear cell and endometrioid subtypes. They grow in a stepwise manner, shows low response toward platinum-based chemotherapy and mostly relate to MAPK pathway mutations. High-grade serous ovarian carcinomas which are often found in rapid-aggressive progression with poorer prognosis are suggested as type II pathway. Their major mutations are mainly in TP53. Optimal surgery and adjuvant chemotherapy are the treatment for both confined and advanced cancers. However, the optimal cytoreduction in type II pathway is becoming more important to increase overall survival or disease-free interval. The strategy of screening type II pathway is proposed to be shifted from detection of stage I tumors to detection of minimal ovarian carcinomas probably by biomarkers since the rapid inception is hardly found. Meanwhile the BRCA1/2 screening and classification should be improved for the hereditary breast/ovarian cancer screening. Mutations of KRAS, BRAF, PTEN and CTNNB1 occur majorly in the type I tumors. Therefore, targeted chemotherapy and inhibitor treatments which are investigated foremost in type II recurrence of ovarian malignancies may also be directed to the low response of type I pathway to platinum-based chemotherapy. Conclusion: A different strategy based on the tumorigenesis of ovarian cancer should be considered in term of screening, primary approach and following chemotherapy since there are some distinctive patterns in both pathways. [Indones J Obstet Gynecol 2009;33-4:239-46] Keywords: ovarian cancer, carcinogenesis, screening, cytoreduction, chemotherapy
Effectiveness of psychoeducation of postpartum depression (a study in health services in subprovince Nias, North Sumatra) Nazara, Yafeti
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To evaluate the effectiveness of psycho-education intervention which is given to postpartum mothers in preventing the existence of postpartum depression and its relation to age, parity, occupation, education and family support. Methods: This research used a quasi experimental with post test only design. Research was implemented at public hospital of Gunung Sitoli and five community health centres in Sub-Province of Nias taken by random on since May - July 2006. There were 85 mothers with normal childbirth as samples. They were accompanied by their husband, condition of mothers and their babies were healthy without any complication. This research used an Edinburg Pascasalin Depression Scale questionnaire as instrument and psycho- education intervention was given with a booklet as media. Results: 85 subjects were included, 40 were intervention group and 45 control group. This research showed that psycho-education intervention was effective significantly (p= 0,001), Odds Ratio (OR): 5,924 (95 % CI : 2,081-16,868) to prevent the postpartum depression occurrence. The most dominant variable in effectiveness of psycho-education intervention is family support variable with pvalue is p = 0,001, OR : 80 (95 % CI : 6,069-1054,570). Conclusion: Psycho-education intervention is very effective for preventing the postpartum depression occurrence after controlled by family support factor. [Indones J Obstet Gynecol 2009;33-4:216-23] Keyword: psycho-education, postpartum depression, family support.
Serum Anti Mullerian Hormone level as ovarium response predictor at women received ovarium stimulation invitro Soebijanto, Soegiharto
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To evaluate clinical value of basal anti-Mullerian Hormone level as predictor of ovarian response to stimulation in women following in vitro fertilization program; compared with Follicle Stimulating Hormone (FSH), estradiol and basal antral follicle. Method: Research was conducted in Yasmin Clinic Cipto Mangunkusumo Hospital as tertiary referral center for reproductive health and in vitro fertilization. Infertile patients which going to undergo controlled ovarian hyper stimulation cycle for in vitro fertilization were checked for basal FSH level, estradiol level, AMH level and amount of basal antral follicle. We were divided the sample into two categories; poor responders and good responders. Statistical analysis using ANOVA was done to evaluate demographic data and Receiver Operator Characteristic area under curve (ROCAUC), and to analyze whether AMH was more superior than the other 3 predictors and to get the cut off point for AMH level. Result: We have collected 22 patients data; 14 were categorized as good responders and 8 were bad responders. Mean AMH value in the good responders group was 4.46±1,01 and in the poor responders group was 1,35±0,96, with p 0,000. According to ROCAUC, AMH is a good predictor for good ovarian response in patient who are a good responders (AUC 0,821), compared to the other three predictors (FSH, E2 and basal antral follicle). Anti Mullerian Hormone cut-off point level is 3, which means value
The effect of letrozole and clomiphen citrate in mature follicle count, ovulation and endometrial thickness in unovulated cycle women Maryati, Sri
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know the efficacy of letrozole and clomiphene citrate for ovulation induction in anovulation women. Method: During the period of January-October 2007, 44 women who met criteria for an ovulation age 18-35 years old, were done anamnesis, physical examination, USG, and hormonal analysis (FSH, LH, E2, Progesterone and Prolactin). All participants were divided into letrozole and clomiphene citrate group. For the letrozole group received 2,5 mg letrozole daily on 3th until 7th day menstrual cycle. The clomiphene citrate group received 50 mg twice a day, on 3th until 5th day menstrual cycle. On 12th menstrual cycle the ultrasound examination was perfomed to measure number of mature follicle and endometrial thickness. On the 18th day of menstrual cycle, ultrasound was perfomed to evaluate ovulation. Result: There was significant difference between letrozole group and clomiphene citrate group (p=0.04) with the number if follicles in letrozole group is 1.08 (±0.27), in clomiphene citrate group 1.40 (±0.51). There was no significant different in mean of follicle size (p=0.32). Ovulation in both groups was not significantly different (p=0.53), 59% in letrozole group and 68% in clomiphene citrate group. There was significant difference in endometrial thickness, mean of endometrial thickness in letrozole group is 8.77 mm (±2.32 mm) and in clomiphene citrate group 6,66 mm (±2.34 mm) (p
Hubungan pengetahuan dan sikap bidan tentang rujukan kasus obstetri dengan ketepatan rujukan: suatu studi analisis verifikatif di Kabupaten Bantul, Yogyakarta Wahyuningsih, Heni Puji
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Memperoleh informasi mengenai ketepatan rujukan kasus obstetri oleh bidan di Kabupaten Bantul, Yogyakarta. Metode: Rancangan penelitian ini menggunakan metode survei eksplanatoris terhadap pengetahuan dan sikap bidan tentang rujukan kasus obstetri dengan ketepatan rujukannya. Data dikumpulkan secara potong silang, dengan rancangan retrospektif (kasus-kontrol). Subjek penelitian 109 responden. Analisis data menggunakan prosedur analisis uji t, Mann-Whitney, uji Chi-Kuadrat, uji korelasi VCramer dan analisis regresi logistik ganda. Hasil: Pada penelitian ini didapatkan bahwa terdapat perbedaan skor pengetahuan berdasarkan rujukan tepat vs tidak tepat (81,2 vs 63,6; p
Cytology of uterine cervix after one year use of Depo Provera and Cyclofem Kambu, Jan Pieter
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: The objective was to examine cervical cytology findings from conventional Pap smear examination in Depo-Provera® and Cyclofem® acceptor in one-year period. Method: The study design is descriptive observational involving 35 Depo-Provera® and 35 Cyclofem® acceptor. We follow up their cytology findings prospectively. This study was conduct in FER and gynecology clinics at Dr. Kariadi Hospital Semarang also at Halmahera and Ngesrep public health service. The subjects were women, aged 20 - 40 years old who chosen Depo-Provera® and Cyclofem® as their contraceptive methods. This study began on December 2006, all subjects who met inclusion criteria underwent initial cytology screening. On December 2007, and there were 70 subjects. They underwent cytology examination at month sixth (simultaneously with third Depo-Provera® injection and seventh Cyclofem® injection) and at month twelve (simultaneously with fifth Depo-Provera® injection and thirteenth Cyclofem® injection). Distribution frequency was analyzed using univariate analysis and data shown as mean and standard deviation whereas bivariate analysis was conduct with X2 and t-test. Cytology examination was conduct in anatomy pathology laboratory at Medicine Faculty, Diponegoro University/Dr. Kariadi Hospital, Semarang. Result: Inflammation rates tend to increase on Depo-Provera® group compare to Cyclofem® group. At first cytology result there is no difference between two groups, it suggest that both groups had same baseline characteristic. Thereafter, at second and third examination, Depo-Provera® group significantly showed higher inflammation and dysplasia rates compare to Cyclofem® group. Conclusion: After one-year period, there was difference on cervical cytology results that is inflammation rates which higher on Depo- Provera® acceptor compare to Cyclofem®. [Indones J Obstet Gynecol 2009; 33-4: 233-8] Keywords: pap smear, Depo-Provera®, Cyclofem®, Pap smear on hormonal contraception

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