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Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)

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Published by Perkumpulan Obstetri dan Ginekologi Indonesia

ISSN : 23386401 EISSN : 23387335 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.

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Articles 17 Documents

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Search results for , issue " Volume. 36, No. 4, October 2012" : 17 Documents clear

Lamellar Body Count has Higher Sensitivity and Specificity in the Prediction of Neonatal Respiratory Distress Syndrome Pradana, Aryando
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.778 KB)

Objective: The study was designed to acquire the cut-off value for lamellar body count and its role in predicting the presence of Respiratory Distress Syndrome (RDS) in pregnancy with gestational age above 28 weeks. Method: Amniotic fluid specimens were collected by amniotomy during cesarean section from women with gestational age above 28 weeks. A haematology analyzer (Advia 120) was used to determine the lamellar body counts. We also performed foam stability test and observed the development of respiratory distress syndrome. Receiver operating characteristics curve was estimated to assess the threshold of lamellar bodies count that may predict the presence of Respiratory Distress Syndrome. Result: Fifty nine specimens were collected from woman with 29 - 42 weeks gestational age. The incidence of Respiratory Distress Syndrome was 15.3%. Area under the curve for lamellar body count was 0.94. Lamellar body count, with the best cut-off point of 50,000 cell/Î¼l had sensitivity 89% and specifity 92% for predicting the presence of RDS, while the sensitivity of foam stability test was 67% and specificity was 90%. The negative predictive value of the lamellar body count was 98% slightly better than the negative predictive value of the foam stability test 94 %. Conclusion: Although both test are good predictor of RDS, lamellar body count has higher sensitivity and specificity. It also has more advantages as it only requires small amount of sample, fast, easy and more objective. [Indones J Obstet Gynecol 2012; 36-4: 176-80] Keywords: foam stability test, lamellar body, respiratory distress syndrome

Evaluation of Combination Chemotherapy Effect of Platinum, Vincristin, Bleomycin, and Mitomycin C on Cervical Cancer Based upon Apoptosis Description Hasan, Agus
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.64 KB)

Objective: To observe the success of platinum, vincristin, bleomycin and mitomycin C (PVB-MMc) combination chemotherapy on cervical carcinoma by evaluating apoptosis feature. Methods: This study was performed at Dr. Wahidin Sudirohusodo Hospital and several other hospitals. The method of this study was prospective longitudinal. Cervical biopsy was performed on 15 cervical carcinoma patients before and after PVB-MMc chemotherapy. Six patients were at early stage and 9 patients were at advanced stage. Biopsy result were sent to pathologic anatomic laboratory to be made into paraffin block and further examined for apoptosis with Tunel method. Data were analyzed by using Wilcoxon Signed Rank test. Results: Study results indicating no significant difference for apoptosis index before and after PVB-MMc chemotherapy for early stage (p=0.463), advance stage (p=0.594), but quantitatively there were increasing apoptosis index before and after chemotherapy. Conclusion: Chemotherapy combination PVB-MMc for cervix carcinoma can increase apoptosis index and give a good response in term of reducing the tumor size although statistically not significant. [Indones J Obstet Gynecol 2012; 36-4: 200-5] Keywords: apoptosis, cervical carcinoma, PVB-MMc combination chemotherapy.

Placental Growth Factor Level is Lower in Early-Onset Preeclampsia, while Tumor Necrosis Factor Alpha Level does not Show any Difference between Early and Late Onset Preeclampsia Ekapatria, Christofani
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.737 KB)

Objective: To analyze the difference of PlGF and TNF-Î± serum level between early-onset and late-onset preeclampsia. Method: This is a cross-sectional analytic comparative study comparing serum level of PlGF and TNF-Î± between groups with earlyand late-onset preeclampsia. Each group consists of 32 subjects who met inclusion criteria and presented to Dr. Hasan Sadikin Hospital or its district hospitals in September - November 2012. Statistical analysis was performed with Kolmogorov Smirnov test, Saphiro-Wilk test, and non-parametric Mann-Whitney test. Result: Mean of PlGF serum level in the group with early-onset preeclampsia is 53.0344Â±38.07140 pg/ml, while mean of which in the group with late-onset preeclampsia is 241.8063Â±192.8373 pg/ml (p

Giant Condyloma Acuminatum in a Woman with AIDS Nuranna, Laila
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Objective: To describe a case of Giant Condyloma Acuminatum with aspect of HIV and some concerns about the CD4. Result: We describe 2 cases, the first case is a giant Condyloma in HIV patient and the second case is a giant Condyloma in pregnant woman. The patient in the first case was a 40-year-old woman with AIDS (CD4 is 290) who was undergoing anti-retroviral therapy. She was found to have a giant condyloma acuminatum of the vulva. Electrocautery excision was performed, and afterwards the quality of life has improved significantly. The second case patient is a 30-year-old G4P3A0 woman with a giant condyloma acuminatum. She was 30 weeks pregnant with a single fetus. On the external genitalia there was a giant condyloma mass on the vulva extending towards the peri-anal area, obstructing the introitus. The electrocautery excision was performed. She was discharged from the hospital on the second day in good condition. She had a spontaneous delivery after reaching full term. Conclusion: Although the giant Condyloma Acuminatum is combined with HIV, but itâs not as difficult as imagined because the tumorâs base is not wide, but shaped like inverted mushroom and it is not necessary to do local flap reconstruction. [Indones J Obstet Gynecol 2012; 36-4: 206-10] Keywords: electrocautery excision, giant condyloma acuminatum, surgery in AIDS

A Comparison between the Level of Interleukin 10 (IL-10) in Aterm and Preterm Labor Lisangan, Yusri
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (95.914 KB)

Objective: To compare the level of interleukin 10 in aterm and preterm labor. Method: The research was conducted from November 1st 2011 until January 31st 2012. The subjects were pregnant women underwent labor during the period who had agreed to participate in this study. The study was conducted in the Obstetrics and Gynecology departments of several teaching hospitals of Hasanuddin University in Makassar. The study design was cross sectional with 48 samples. The data were analysed by using the Mann Whithney test. Results: The result revealed that there was an increase of interleukin 10 level in mothers with preterm labor, in comparison with the control group (p < 0.05). Conclusion: The level of interleukin 10 in mothers with preterm labor are higher than aterm labors less than espective. [Indones J Obstet Gynecol 2012; 36-4: 163-6] Keywords: interleukin 10, preterm labor

Progesterone Serum Level in-Labor Women does not Differ with not in-Labor Women Hutomo, Caroline
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (89.959 KB)

Objectives: To find out the relation of serum progesterone level between patients in-labor and pregnant patients not in-labor. Methods: This was an analytic cross-sectional study, comparing serum progesterone level between in-labor gravida and not in-labor gravida. Subjects were in-labor gravida (n=21) and not in-labor gravida (n=24) admitted to Sanglah Hospital from April to August 2011. The data were analyzed by SPSS 16.0. Independent sample ttest and Fisherâs exact test were used. Results: Mean serum progesterone level were 214.90Â±92.06 inlabor gravida and 190.69Â±76.02 not in-labor gravida (t = 0.966 and p = 0.399). Conclusions: There is no difference in serum progesterone level between in-labor and not in-labor pregnant women. [Indones J Obstet Gynecol 2012; 36-4: 185-7] Keywords: labor, progesterone, progesterone withdrawal

Elastin Expression in Sacrouterina Ligament is Weaker in the Women with Pelvic Organ Prolapse Hasnawati, Andi
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.553 KB)

Objective: The research aims at comparing the elastin immunolabeling in the uterosacral ligaments in women with pelvic organ prolapse and without pelvic organ prolapse (POP). Methods: The research is done at Dr. Wahidin Sudirohusodo Hospital and education networking some hospitals the Obstetrics and Gynecological School of Medicine Hasanuddin University that began in January 2011 until April 2012. This research assessing expression of elastin on 35 women with a pop level III and IV and as control is 35 women without POP. Immunolabeling of elastin valued in staining checkings immunohistokimia uses antibodies elastin ( clone no. Ba-4 1:1600; Novacastra Laboratories Ltd, UK). The research was carried out by the cross sectional study. Mixed with chi-square. Level significance used is 0.05. Results: The results showed that the elastin immunolabeling in women with POP is decline on most sample expression with the intensity of elastin is weak (74.3%). The most control with the intensity of elastin immunolabeling is moderate (48.6%). Elastin immunolabeling seem significant in women with menopause and with BMI that overweight (all with p

The Level of Zinc is Increasing, while the Serum Folat Level is Decreasing, after Multi-Micronutrient Supplementation in Pregnant Woman Wibowo, Noroyono
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.758 KB)

Objective: To measure the changes of serum iron, folic acid, zinc and selenium level on pregnant woman after multi-micronutrient supplementation. Method: First trimester pregnant woman whom attended Maternal- Fetal Policlinic at Dr. Cipto Mangunkusumo Hospital from July 2011 till October 2011 was considered into the study. The intervention was consumption of multi-micronutrient tablet once a day for three months period. The outcomes were the measurements of serum level of iron, folic acid, zinc and selenium before and after supplementation. We used paired T Test and Wilcoxon test for statistical analysis. Results: Twenty-eight pregnant women in their first trimester participated in the study. The micronutrient serum level was measured before and after supplementation during the time period. Before supplementation, serum iron and zinc level were below normal. Serum selenium level was normal with higher than normal serum folic acid level. After supplementation, serum zinc level was found to be below normal. Both level of serum iron and selenium increased to normal. Serum folic level was higher than normal. We found a decrease in serum zinc level with an increase in serum folic acid level that was statistically significant (p 0.009; p 0.003 respectively). We also found a slight decrease of serum iron level and an increase of serum selenium level that were not statistically significant (p 0.295; p 0.333). Conclusion: There is a decreased level of serum zinc with an increase in serum folic acid level after multi-micronutrient supplementation. [Indones J Obstet Gynecol 2012; 36-4: 171-5] Keywords: multi-micronutrient, supplementation

Expression of Fas Ligand is Higher in Early Stage Cervical Cancer with Lymph Nodes Metastasis Irwanto, Yahya
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.225 KB)

Objective: To know whether the expression of Fas Ligand has correlation with incidene of metastasis of pelvic lymph node and lymph-vascular stromal invasion (LVSI). Methods: All patients diagnosed of cervical cancer stage IB or IIA who underwent radical hysterectomy in Dr. Cipto Mangunkusumo Central General Hospital from January 2008 until December 2009 were included in analytic cross sectional study. We tested expression of Fas Ligand in cervical cancer specimen by immunohystochemistry with monoclonal antibody. The expression of Fas Ligand was compared between the group of patients with a positive and negative pelvic lymph node and between LVSI positive and negative. The difference of expression in both group were statistically analized with Chi-square test and the correlation Spearman test. Result: Ninety one patients underwent radical hysterectomy for two years and 43 patients were included in these study. The expression of Fas Ligand in 7 patients (16.3%) were negative and the others were positive, with weak, moderate and strong expression were 4 (9.3%), 27 (62.8%), and 5 (11.6%) respectively. The expression of Fas Ligand was significantly higher in the group of patients with positive pelvic lymph node compared to the group of the patients with negative pelvic lymph node (p=0.007) but there was no significant difference between group of the patients with LVSI positive and negative. With Spearman test, we found that the expression of Fas Ligand had a strong correlation with pelvic lymph nodes metastasis (coeff. correlation=0.519 and p=0.00) and have no correlation with LVSI (coef. corellation=0.112 and p=0.474). Conclusion: These finding suggested that expression of Fas Ligand in cervical cancer patients has a strong correlation with the incidence of pelvic lymph node metastasis and none with LVSI. [Indones J Obstet Gynecol 2012; 36-4: 194-9] Keywords: cervical cancer, fas ligand, immunohystochemistry, LVSI, pelvic lymph node metastasis

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eko subaktiansyah

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eko.subaktiansyah@gmail.com

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support@inajog.com

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Location
Kota adm. jakarta pusat,

Dki jakarta

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