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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
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Articles 10 Documents
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Search results for , issue "Volume 10 No. 2 April 2022" : 10 Documents clear
The Efficacy of Chemotherapy in Advanced-Stage Cervical Cancer on Vitamin A Serum: Efektivitas Kemoterapi pada Karsinoma Serviks Stadium Lanjut terhadap Serum Vitamin A Raissa N. Rizal; Rizal Sanif; Amirah Novaliani; Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1458

Abstract

Abstract Objective: To determine the efficacy of neoadjuvant chemotherapy on changes of vitamin A serum in advanced cervical carcinoma patient. Method: A randomized clinical trial was performed in the Oncology Gynecology Polyclinic and Ward of Dr. Mohammad Hoesin General Hospital, Palembang from September 2019 to September 2020. There were 30 subjects of advanced cervical carcinoma. Vitamin A levels and tumor volume subjects were assessed before and 1 month after 3 cycles of NAC and analyzed using the Paired T Test and Wilcoxon test. The correlation between vitamin A levels and tumor volume was analyzed by using Spearman's Rho test. Data analysis was using SPSS version 22.0. Results: This study showed statistically not significant increase on vitamin A levels after 3 cycles of NAC chemotherapy (p=0.515). However, there was a significantly decrease in tumor volume after 3 cycles of NAC (p=0.000). In addition, there was a moderate negative correlation between tumor size and vitamin A (r=-0.475; p=0.008). Conclusion: It can be concluded that there was significantly decrease in tumor volume after 3 series NAC chemotherapy and the smaller tumor size, the higher level of vitamin A serum. Keywords: cervical cancer, neoadjuvant chemotherapy, randomized clinical trial, vitamin A, Abstrak Tujuan: Untuk mengetahui efektivitas kemoterapi neoadjuvan terhadap perubahan kadar serum vitamin A pada karsinoma servik stadium lanjut. Metode: Penelitian uji klinik tanpa pembanding telah dilakukan di Poliklinik dan Bangsal Onkologi Ginekologi RSUP Dr. Muhammad Hoesin Palembang sejak September 2019 hingga September 2020. Didapatkan 30 sampel karsinoma serviks stadium lanjut. Kadar vitamin A dan volume tumor dinilai sebelum dan 1 bulan setelah 3 siklus NAC dan dianalsis menggunakan uji Paired T Test dan Wilcoxon. Korelasi antara Kadar vitamin A dan volume tumor sampel dianalisis menggunakan uji Spearman Rho’s. Analisa data menggunakan SPSS versi 22.0. Hasil : Pada penelitian ini terdapat peningkatan tidak signifikan kadar vitamin A setelah kemoterapi (p = 0,515). Terdapat penurunan secara signifikan volume tumor sebelum dan sesudah kemoterapi NAC 3 seri (p = 0,000). Selain itu, didapatkan korelasi negatif sedang yang bermakna antara ukuran tumor dan kadar vitamin A ( r = -0,475 ; p = 0,008). Simpulan : Disimpulkan bahwa terdapat penurunan volume tumor setelah kemoterapi NAC 3 series dan semakin kecil ukuran tumor maka semakin tinggi kadar vitamin A dalam serum. Kata kunci: kanker serviks, kemoterapi neoadjuvan, uji klinik tanpa pembanding, vitamin A.
Treatment Approach for A Rare Case of Cervical Cancer in Pregnancy : Pendekatan Terapi pada Kanker Serviks dalam Kehamilan Yuannita I. Putri; Gumilang Wiranegara
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1517

Abstract

Abstract Objective: To add a new overview of cervical cancer in pregnancy and to review several treatment approaches using available guidelines. Methods: Case report. Case: A 29 years old woman, gravida 3 para 2 in 10 weeks of pregnancy, was presented with vaginal bleeding and bloody vaginal discharge. Ultrasound examination showed a 10 weeks single live intrauterine fetus and a mass on the cervix. The histopathological report revealed a poorly differentiated cervical adenocarcinoma without invasion of lymphovascular space. Patient was diagnosed with cervical carcinoma FIGO stage IB3 in 10 weeks of pregnancy. The patient opted to unpreserved the pregnancy. Radical hysterectomy with fetus in situ and bilateral pelvic lymphadenectomy was performed. Patient was referred to undergo adjuvant radiation therapy. Conclusion: Cervical cancer in pregnancy is a rare and special condition that requires individual planning for the diagnostic and treatment approaches. Keywords: cervical cancer, cervical cancer in pregnancy, fetus in situ hysterectomy, pregnancy, radical hysterectomy. Abstrak Tujuan: Untuk menambah gambaran kasus mengenai kanker serviks dalam kehamilan serta membahas pendekatan terapi menggunakan pedoman – pedoman yang ada. Metode: Laporan kasus. Kasus: Seorang perempuan berusia 29 tahun dengan G3P2 usia kehamilan 10 minggu datang dengan keluhan perdarahan pervaginam dan keputihan bercampur darah. Hasil dari USG menunjukkan adanya janin berusia 10 minggu serta massa pada serviks. Hasil pemeriksaan histopatologi menunjukkan adanya adenokarsinoma serviks berdiferensiasi buruk tanpa invasi limfovaskuler. Pasien didiagnosis dengan kanker serviks stadium FIGO IB3 dalam kehamilan 10 minggu. Pasien setuju untuk dilakukan terminasi kehamilan. Pada pasien kemudian dilakukan laparotomi histerektomi radikal dengan fetus in situ serta limfadenektomi pelvik bilateral. Pasien kemudian dirujuk untuk dilakukan terapi ajuvan dengan radiasi. Kesimpulan: Kanker serviks pada kehamilan merupakan suatu kondisi khusus sehingga perencanaan diagnostik dan manajemen terapi membutuhkan perencanaan secara individual di setiap kasusnya. Kata kunci: Kanker, kanker serviks, kanker serviks dalam kehamilan, kehamilan, , histerektomi radikal, histerektomi dengan fetus in situ.
Estradiol on Day Seven is a Good Predictor for Oocyte Maturation Rate in In Vitro Fertilization Program: Kadar estradiol hari ketujuh sebagai prediktor tingkat kematangan oosit pada program Fertilisasi In Vitro Andon Hestiantoro; Betaria Putri; Eka R. Gunardi; Yudianto B. Saroyo; Muharam Natadisastra
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1539

Abstract

Abstract Objective: to determine which factors influence the rate of oocyte maturation in In Vitro Fertilization (IVF) program. Methods: A retrospective cohort study was conducted using secondary data from IVF participants at the Yasmin Fertility Clinic, Dr. RSUP. Cipto Mangunkusumo, Jakarta, Indonesia during the period January 2019 to December 2020, as recorded in the InaRepromed archive. The variables analyzed were age, body mass index, and hormone levels on day 1, day 7, and day hCG, with oocyte maturation rate as the main outcome. Correlation test was performed between several variables and the level of oocyte maturation rate and followed by multivariate analysis to assess the factors that were closely related to oocyte maturation rate. Results: Data from 52 subjects were collected for the study. Positive correlation was observed between oocyte maturation rate and estradiol on day 7 (r = 0.229), while negative correlation was observed between oocyte maturation rate and progesterone/estradiol ratio on day 7 (r = -0.289) and luteinizing hormone on day 1 (r = -0.265). Multivariate analysis revealed that higher estradiol on day-7 was associated with better oocyte maturation rate (p = 0.047). Conclusion: Higher estradiol level on day 7 was associated with better oocyte maturation rate in IVF. Keywords: Assisted reproductive technology (ART), estradiol, in vitro fertilization (IVF), progesterone. Abstrak Tujuan: untuk menentukan faktor-faktor yang mempengaruhi tingkat pematangan oosit dalam program Fertilisasi InVitro (FIV). Metode: Desain penelitian adalah kohort retrospektif, menggunakan data sekunder peserta bayi tabung Klinik Fertilitas Yasmin, RSUP Dr. Cipto Mangunkusumo, Jakarta, Indonesia selama periode Januari 2019 hingga Desember 2020, yang tercatat di dalam arsip InaRepromed. Variabel yang dianalisis adalah umur, indeks massa tubuh, dan kadar hormon pada hari ke-1, hari ke-7, dan hari ke-hCG, dengan tingkat maturasi oosit sebagai luaran utama. Dilakukan analisis korelasi antara beberapa variabel dengan tingkat maturasi oosit, dan dilanjutkan dengan analisis multivariat untuk menilai faktor-faktor yang berhubungan kuat dengan tingkat maturasi oosit. Hasil: Data dari 52 subjek dikumpulkan untuk penelitian ini. Dijumpai korelasi positif antara tingkat maturasi oosit dan estradiol pada hari ke 7 (r = 0,229), sedangkan korelasi negatif diamati pula antara tingkat maturasi oosit dan rasio progesteron/estradiol pada hari ke 7 (r = -0,289) dan hormon luteinisasi pada hari 1 (r = -0,265). Analisis multivariat mengungkapkan bahwa estradiol yang lebih tinggi pada hari ke-7 dikaitkan dengan tingkat maturasi oosit yang lebih baik (p = 0,047). Kesimpulan: Kadar estradiol yang lebih tinggi pada hari ke 7 dikaitkan dengan tingkat pematangan oosit yang lebih baik pada program FIV. Kata kunci : Teknologi reproduksi berbantu (TRB), estradiol, fertilisasi in vitro (IVF), progesteron.
The Impact of Premature Rupture of Membranes (PROM) and Low Birth Weight (LBW) Infant Outcomes to the Survival Rate : Hubungan Ketuban Pecah Dini (KPD) dengan Luaran Bayi Berat Badan Lahir Rendah (BBLR) terhadap Survival rate setelah Satu Minggu Dilahirkan Hasanuddin; Dannu Wijaya; Dora Darusalam
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1553

Abstract

Abstract Objective: To determine the impact of premature rupture of membranes and the outcome of low birth weight on the survival rate one week after birth in RSUDZA Banda Aceh. Method: This study used an observational analytic study with a prospective cohort study design. The research samples were 84 samples that met the inclusion and exclusion criteria. The data source used was primary data obtained by direct examination by weighing the newborn at birth and during visits. Results: There was an impact of premature rupture of membranes and the outcome of low birth weight on the survival rate of infants after one week. The results showed that the p-value <0.000. The lowest neonatal survival rate was in the group weighing less than 1000 grams, namely 0%. Weight group 1000 grams to 1500 grams with a survival rate of 55% and group weight 1500 grams to 2500 grams with a survival rate of 95%. Discussion: There was an impact of premature rupture of membranes and the outcome of low birth weight on the survival rate one week after birth in RSUDZA Banda Aceh. Keywords: low birth weight (LBW), preterm premature rupture of membranes, survival rate. Abstrak Tujuan : Untuk mengetahui dampak ketuban pecah dini dengan luaran berat badan lahir rendah terhadap survival rate satu minggu setelah dilahirkan di RSUDZA Banda Aceh. Metode: Penelitian ini menggunakan studi analitik observasional dengan desain penelitian kohort prospektif. Sampel penelitian sebanyak 84 sampel yang memenuhi kriteria inklusi dan eksklusi. Sumber data yang digunakan adalah data primer yang diperoleh dengan cara pemeriksaan langsung dengan penimbangan bayi saat baru lahir dan ketika kunjungan. Hasil: Ada dampak ketuban pecah dini dengan luaran berat badan lahir rendah terhadap survival rate bayi setelah satu minggu didapatkan hasil bahwa p-value <0,000. Survival rate neonatal terendah pada kelompok berat badan di bawah 1000 gram yakni 0%. Kelompok berat badan 1000 gram sampai di bawah 1.499 gram memiliki survival rate 55% dan kelompok berat badan 1.500 gram sampai 2.499 gram memiliki angka survival rate 95%. Diskusi: Ada dampak ketuban pecah dini dengan luaran berat badan lahir rendah terhadap survival rate satu minggu setelah bayi dilahirkan di RSUDZA Banda Aceh. Kata kunci: berat badan lahir rendah (BBLR), ketuban pecah dini, survival rate.
Progress of Labor Onset with Combination of Pregnancy Massage and Acupressure: Kemajuan Awal Persalinan dengan Kombinasi Pijat Kehamilan dan Akupresur Milatun Khanifah; Chabibah Nur; Siti Khuzaiyah
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1554

Abstract

Abstract Objective: To investigate effectiveness of complementary therapy combination pregnancy massage and acupressure on the onset of labor in primigravida pregnant women. Methods: The population was pregnant women in all regions of Pekalongan Regency at more than 39 weeks' gestation, using random cluster sampling. Data collect use an observation sheet to measure the start time of labor and also check the implementation of massage and acupressure in pregnancy. Treatment was carried out every 2-3 days from 39 weeks of gestation until labor occurs. This study was quantitative quasi-experimental with control group design with a cohort approach. Results: The results of the bivariate analysis showed that there were significant differences in the onset of childbirth in the intervention group with the control group (p-value; 0.003; CI -8.59 - (- 2.07)). It was concluded that complementary therapy combined therapy of pregnancy massage and acupressure could be used as an alternative therapy to prevent overdue pregnancy Conclusions: These findings confirm that complementary therapy combination pregnancy massage and acupressure could faster the onset of labor. Keywords: acupressure, complementary therapy, onset labor, pregnancy massage. Abstrak Tujuan: Untuk mengetahui efektivitas terapi komplementer kombinasi pijat kehamilan dan akupresur pada permulaan persalinan pada ibu hamil primigravida. Metode: Populasi dalam penelitian ini adalah ibu hamil di seluruh wilayah Kabupaten Pekalongan dengan usia kehamilan lebih dari 39 minggu, dengan menggunakan sampel cluster random. Pengumpulan data menggunakan lembar observasi untuk mengukur waktu mulai persalinan serta memeriksa pelaksanaan pijat dan akupresur pada kehamilan. Pengobatan dilakukan setiap 2-3 hari dari usia kehamilan 39 minggu sampai terjadi persalinan. Penelitian ini merupakan penelitian kuasi eksperimental kuantitatif dengan desain kelompok kontrol dengan pendekatan kohort. Hasil: analisis bivariat menunjukkan terdapat perbedaan yang signifikan timbulnya persalinan pada kelompok intervensi dengan kelompok kontrol (p-value; 0,003; CI -8,59 - (- 2,07)). Disimpulkan bahwa terapi komplementer terapi kombinasi pijat kehamilan dan akupresur dapat digunakan sebagai terapi alternatif untuk mencegah terjadinya kehamilan terlambat. Kesimpulan: Temuan ini mengkonfirmasi bahwa terapi komplementer kombinasi pijat kehamilan dan akupresur dapat mempercepat terjadinya persalinan. Kata kunci: akupresur; awalan persalinan, pijat kehamilan ,terapi komplementer.
The Role Placental TLR-7 Expression with Cord Blood HBV DNA and Placental HBV DNA: Peran Ekspresi TLR-7 Plasenta dengan HBV DNA Tali Pusat dan HBV DNA Plasenta Naeny Fajriah; Maisuri T. Chalid; Lenny Lisal; Efendi Lukas; St. Nur Asni; Rina Masadah
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1564

Abstract

Abstract Objective: To determine the role of TLR-7 expression on intrauterine vertical transmission in pregnancy through identification of serum hepatitis B markers in both maternal and umbilical cord blood. Methods: Analysis of TLR expression was performed on 38 paraffin block samples of placental tissue acquired from mothers with HBV using TLR immunohistochemical staining. Results: 16 of 38 samples were acquired from mothers aged 26-30 years-old. Most of the samples were from primiparous mothers (52.6%). This study found no significant association between TLR-7 expression and HBV DNA in the placenta and cord blood (p = 1.000). However, we found a significant association between placental TLR-7 expression and maternal HBV DNA (p = 0.034). Meanwhile, placental HBeAg and HBV DNA were not associated with placental TLR-7 expression (p = 0.082; p = 1.000). Conclusion: There was no significant association between TLR-7 expression and HBV DNA in the placenta and cord blood, but we found a significant association between TLR-7 expression and maternal HBV DNA. Keywords: HBV DNA, Hepatitis B, intrauterine infection, placental toll-like receptor (TLR) 7,umbilical cord. Abstrak Tujuan: untuk melihat peran ekspresi TLR-7 terhadap transmisi vertikal intrauterina pada kehamilan melalui identifikasi marker serum hepatitis B pada darah ibu dan talipusar. Metode: Analisis ekspresi TLR dilakukan pada 38 sampel blok paraffin jaringan plasenta ibu yang menderita HBV dengan memakai pewarnaan imuhohistokimia TLR. Hasil: 16 dari 38 sampel berusia 26-30 tahun. Sebagian besar sampel merupakan kelompok primipara (52.6%). Penelitian ini tidak menemukan hubungan yang signifikan antara ekspresi TLR-7 di plasenta dan HBV DNA darah tali pusat (p = 1.000). Tapi, kami menemukan hubungan yang signifikan antara ekspresi TLR-7 plasenta dan HBV DNA ibu (p = 0,034). Sedangkan HBeAg dan HBV DNA plasenta tidak berhubungan dengan ekspresi TLR-7 plasenta (p = 0,082; p = 1.000). Kesimpulan: Tidak ada hubungan yang signifikan antara ekspresi TLR-7 dan DNA HBV di plasenta dan tali pusat, tetapi kami menemukan hubungan yang signifikan antara ekspresi TLR-7 dan DNA HBV ibu. Kata kunci: HBV DNA, Hepatitis B, infeksi intrauterina, plasenta, tali pusat, toll-like receptor (TLR) 7
High Random Blood Glucose Level before Surgery as a Risk Factor for Recurrent Event in Epithelial Ovarian Carcinoma : Kadar Gula Darah Sewaktu yang Tinggi sebelum Operasi sebagai Faktor Risiko Kejadian Residif pada Pasien Karsinoma Ovarium Tipe Epitelial Anggiyasti V. Hapsari; Teuku M. Iskandar
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1570

Abstract

Abstract Objective : To investigate the high random blood glucose level as a risk factor for recurrent disease in EOC patient at Kariadi General Hospital. Methods: Sixty six patients diagnosed as EOC in Kariadi General Hospital were divided into 2 groups: 30 patients with recurrent disease and 30 patients without recurrent disease after completing chemotherapy cycles. We analysed correlation between age of diagnosis, tumour mass location, Ca-125 level, histological subtype and random blood glucose level before surgery with recurrent disease. Result: There is no significantly difference in age of diagnosis, tumour mass location and histological subtypes between two groups. However, recurrent EOC patients have higher Ca-125 level significantly than non-recurrent patients (327.8±250.5 vs 183.5±212.1 respectively; p = 0,01). Mean of random blood glucose level of recurrent patients is also higher than non-recurrent patients significantly (150.5 ±79 vs 110.8 ± 31.1 respectively; p = 0.006). Patient with random blood glucose level > 110 mg/dl have 3 times more likely to develop recurrence in EOC patient significantly with 95% CI. Conclusion: The mean of random blood glucose level in recurrent EOC patients is significantly higher than non-recurrent EOC patients. Patient with random blood glucose level > 110 mg/dl have 3 times more likely to develop recurrence in EOC patient. Keyword: epithelial ovarian cancer, random blood glucose level, recurrent. Abstrak Tujuan: Untuk membuktikan kadar glukosa darah sewaktu yang tinggi sebagai faktor risiko kejadian residif pada pasien karsinoma ovarium epitelial di RSUP dr. Kariadi. Metode: Enam puluh pasien yang telah didiagnosis sebagai karsinoma ovarium epitelial di RSUP dr. Kariadi dibagi menjadi 2 kelompok: 30 pasien pada kelompok residif dan 30 pasien pada kelompok non-residif berdasarkan evaluasi setelah menyelesaikan siklus kemoterapi. Data yang dianalisis meliputi usia saat terdiagnosis, lokasi tumor, kadar Ca-125, subtipe histologi, kadar gula darah sewaktu (GDS) sebelum operasi dan hubungannya dengan kejadian residif. Hasil: Tidak terdapat perbedaan yang bermakna dalam usia saat diagnosis, lokasi tumor dan subtipe histologis diantara kedua kelompok. Namun, kelompok pasien residif memiliki kadar Ca-125 yang lebih tinggi secara bermakna dibandingkan kelompok pasien non-residif (327,8 ± 250,5 vs 183,5 ± 212,1; p = 0,01). Rerata kadar GDS pada kelompok pasien residif juga lebih tinggi secara bermakna daripada kelompok non-residif (150,5 ± 79 vs 110,8 ± 31,1; p = 0,006). Pasien dengan kadar GDS > 110 mg/dl memiliki risiko 3 kali lipat untuk menjadi residif secara bermakna dengan tingkat kepercayaan 95%. Kesimpulan: Rerata kadar GDS pada kelompok pasien residif lebih tinggi secara bermakna dibanding kelompok pasien non-residif. Pasien dengan kadar GDS > 110 mg/dl memiliki risiko 3 kali lipat untuk menjadi residif Kata kunci: kadar gula darah sewaktu, karsinoma ovarium epitelial, residif.
Prevention and Treatment of Venous Thromboembolism in Pregnancy: Pencegahan dan Tatalaksana Tromboemboli Vena pada Kehamilan Erna Suparman
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1625

Abstract

Abstract Objective: To determine prevention and treatment of venous thromboembolism in pregnancy Methode: Literature Review Results: The diagnosis of TEV, both deep vein thrombosis (DVT) and pulmonary embolism (PE) was clinical and confirmed by imaging. D-dimers commonly used in the non-pregnant population are less useful in pregnant women. Prevention needs to be done by assessing the risk of TEV in pregnant women and giving thrombophylaxis according to risk. Treatment of TEV in pregnant women mainly uses heparin, either unfractionated heparin (UFH) or low molecular weight heparin (LMWH). Conclusion: The ASH recommends the use of LMWH compared with UFH for the management of acute VTE in pregnancy, in once-daily or divided doses. The recommended method of delivery for pregnant women receiving anticoagulant therapy should be planned delivery Key word : vein thromboemboli, deep vein thrombosis, pulmonary embolism, pregnancy Abstrak Tujuan: mengetahui bagaimana pencegahan dan tatalaksana tromboemboli vena pada kehamilan Metode: Kajian Pusataka Hasil: Diagnosis TEV, baik Deep vein thrombosis (DVT) dan pulmonary embolism (PE) berdasarkan klinis dan dikonfirmasi dengan pencitraan. D-dimer yang biasa digunakan pada populasi non-hamil kurang berguna pada ibu hamil. Pencegahan perlu dilakukan dengan menilai risiko TEV pada ibu hamil dan memberikan trombofilaksis sesuai dengan risiko. Tatalaksana TEV pada ibu hamil terutama menggunakan heparin, baik unfractionated heparin (UFH) maupun low molecular weight heparin (LMWH). Kesimpulan: ASH merekomendasikan penggunaan LMWH dibandingkan dengan UFH untuk pengelolaan VTE akut pada kehamilan, dalam dosis sekali sehari atau terbagi. Metode persalinan yang direkomendasikan untuk ibu hamil yang menerima terapi antikoagulan harus direncanakan persalinan Kata kunci : tromboemboli vena, deep vein thrombosis, pulmonary embolism, kehamilan
Obstetric Referral System during COVID-19 Pandemic : Tertiary Referral Hospital Perspective: istem Rujukan Obstetri dalam Masa Pandemi COVID-19 : Perspektif Rumah Sakit Rujukan Tersier Arietta R. D. Pusponegoro; Chakti A. Swastika; Junita Indarti
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1651

Abstract

Abstract Objective : To evaluate the effectiveness of obstetric referrals to the dr. Cipto Mangunkusumo National Central General Hospital (RSCM), a tertiary hospital in Indonesian referral system, during the COVID-19 pandemic. Methods : A cross-sectional descriptive-analytic study that compared the effectiveness of referrals before (July-December 2019) and during the COVID-19 pandemic (March-August 2020) at the National Central General Hospital dr. Cipto Mangunkusumo (RSCM). Referral effectiveness is assessed based on two criteria, namely the suitability of the diagnosis and procedural compliance which includes communication through the integrated emergency response system (SPGDT), delivery by ambulance, and attachment of a referral letter. Results: The study found 198 referral cases from 464 obstetric cases (42.67%) before the pandemic and 231 referral cases from 486 obstetric cases (47.53%) during the pandemic. The diagnostic concordance increased from 57.58% before the pandemic to 71.00% during the pandemic (p = 0.004). Referral procedural compliance increased from 28.28% before the pandemic to 45.45% during the pandemic (p < 0.001). Based on these criteria, the effectiveness of referrals at the RSCM during the COVID-19 pandemic era was found to be significantly higher, namely before the pandemic by 21.72% and during the pandemic by 40.26% (p < 0.001). Conclusion : The effectiveness of referral to the RSCM based on the suitability of the diagnosis and the accuracy of the procedure during the COVID-19 pandemic was found to be better than before the pandemic. Keywords: COVID-19, obstetric referral system, pandemic. Abstrak Tujuan : Untuk menilai efektivitas rujukan obstetri ke Rumah Sakit Pusat Nasional dr. Cipto Mangunkusumo, rumah sakit tersier dalam sistem rujukan Indonesia, selama pandemi COVID-19 Metode: Penelitian deskriptif-analitik berdesain potong lintang yang membandingkan efektivitas rujukan sebelum (Juli-Desember 2019) dan saat pandemi COVID-19 (Maret-Agustus 2020) di Rumah Sakit Umum Pusat Nasional dr. Cipto Mangunkusumo (RSCM). Efektivitas rujukan dinilai berdasarkan dua kriteria, yakni kesesuaian diagnosis dan kepatuhan prosedur yang meliputi komunikasi melalui sistem penanggulangan gawat darurat terpadu (SPGDT), pengantaran dengan ambulans, dan pelampiran surat rujukan. Hasil: Penelitian menemukan 198 kasus rujukan dari 464 kasus obstetri (42,67%) sebelum pandemi dan 231 kasus rujukan dari 486 kasus obstetri (47,53%) saat pandemi. Kesesuaian diagnosis meningkat dari 57,58% sebelum pandemi menjadi 71,00% saat pandemi (p = 0,004). Kepatuhan prosedur rujukan meningkat dari 28,28% sebelum pandemi menjadi 45,45% saat pandemi (p < 0,001). Berdasarkan kriteria tersebut, efektivitas rujukan di RSCM pada era pandemi COVID-19 ditemukan lebih tinggi secara signifikan, yakni sebelum pandemi sebesar 21,72% dan saat pandemi sebesar 40,26% (p < 0,001). Kesimpulan: Efektivitas rujukan ke RSCM berdasarkan kesesuaian diagnosis dan kepatuhan prosedur saat pandemi COVID-19 ditemukan lebih baik. Kata kunci: COVID-19, pandemi, sistem rujukan obstetri
Are Vaccines Safe during Pregnancy ? Johanes C Mose
Indonesian Journal of Obstetrics and Gynecology Volume 10 No. 2 April 2022
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v10i2.1744

Abstract

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