Andon Hestiantoro
Department Of Obstetrics And Gynecology, Faculty Of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta

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The benefits of progesterone therapy in imminent abortion Abadi, A.; Baziad, Ali; Hestiantoro, Andon
Medical Journal of Indonesia Vol 14, No 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.027 KB) | DOI: 10.13181/mji.v14i4.205

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The causes of imminent abortion are multi-factorial. The biggest causal factor is the low level of serum progesterone level. The lowest critical level of serum progesterone for survivability of pregnancy is 10 ng/ml. Eighty percent of patients experiencing abortion showed that their progesterone level was < 10 ng/ml. Patients who realized that their pregnancy would experience hemorrhage generally would suffer from depression. Stress was one of the factors responsible for the occurence of abortion. Administration of natural progesterone substitution (not  progestogen) accelerates the disappearance of uterine contractions, and speeds up the stoppage of bleeding. In addition, progesterone has the effect of anti-anxiety. Adminstration of oral progesterone would result in metabolism in the intestine and liver, such that physiological level of serum progesterone could not be reached, while administration of suppositoria progesterone would result in physiological level of serum, such that it was effective to prevent imminent abortion. (Med J Indones 2005; 14:258-62)Keywords: progesterone, imminent abortion
Internet Based Infertility Information in Bahasa Indonesia Quality Survey Hestiantoro, Andon; Kusumaningtyas, Intan
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.503 KB) | DOI: 10.32771/inajog.v6i1.754

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Objective: To assess the quality of websites providing informationon infertility and its management in Bahasa.Methods: Differences between website types and affiliates wereassessed for the credibility, accuracy and ease of navigation usingpredefined criteria. We used Google search engine with the keyword"infertilitas" and we assessed 50 websites in Bahasa that relates withinfertility.Results: The content credibility for most of the sites has adequatescore with range of score 60 to 80 for 68% sites. Content accuracyfor most of the sites have scores more than 60, with 24% or 12sites with scores 60 to 80 and 44% or 22 sites have scores above80. The ease of navigation for most of the sites, 47 sites or 94%has scores more than 60.Conclusion: The quality of internet based infertility information inBahasa is adequate for category credibility, accuracy and ease ofnavigation.[Indones J Obstet Gynecol 2018; 6-1: 28-33]Keywords: bahasa, infertility, information, internet, quality
INDEX Hestiantoro, Andon
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (73.361 KB) | DOI: 10.32771/inajog.v6i4.935

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Maternal Age, Abortion and Aneuploidy Hestiantoro, Andon
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (57.887 KB) | DOI: 10.32771/inajog.v4i2.74

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The Prevalence and Risk Factors of Constipation in Pregnancy Hestiantoro, Andon; Baidah, Priska A
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.466 KB) | DOI: 10.32771/inajog.v6i2.766

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    Objective: To estimate the prevalence of constipation inpregnancy and correlation between gestational age, dietaryfiber intake, water comsumption, and physical activity.   Methods: This study used cross-sectional design with samples of174 healthy pregnant women undergoing antenatal care atObstetrics and Gynecology Outpatient Clinic RSCM during August -October 2016. Data were collected using questionnaire. Diagnosisof constipation was based on ROME III criteria, dietary fiber ismeasured using Food Frequency Questionnaire (FFQ), and physicalactivity was measured using International Physical Activity Questionnaire(IPAQ). Chi-square and Fisher’s exact test were conducted toevaluate the association between variables.   Results: The prevalence of constipation in pregnant womenobserved in this study was 13.2% (95% CI 8.3-18.1). The mostfrequent complaints included straining, incomplete evacuation,and anorectal obstruction. Dietary fiber intake was low in 81.03%subject. with average dietary fiber intake of 18.97 gram/day.There was no significant association between constipation andgestational age (OR 4.36, 95%CI 0.51-37.48 for second trimesterand OR 2.04, 95%CI 0.25-16.7 for third trimester), dietaryfiber intake (OR 0.82, 95%CI 0.28-2.39), water consumption(OR 1.38, 95%CI 0.56-3.41), and physical activity (OR 1.167,95%CI 0.28-4.87).   Conclusion: Prevalence of constipation in pregnant women is13.2%. There is no significant correlation between gestational age,dietary fiber intake, water consumption, and physical activity.   Keywords: constipation, pregnant woman, ROME III
The Outcome on Conservative Surgical Treatment of Adenomyosis Wiweko, Budi; Legiantuko, Ario; Kemal, Achmad; Pratama, Gita; Situmorang, Herbert; Sumapraja, Kanadi; Natadisastra, Muharam; Hestiantoro, Andon
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.501 KB) | DOI: 10.32771/inajog.v4i4.448

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Objective: To understand the outcome on conservative surgical treatment of adenomyosis. Methods: A retrospective cohort study followed for 2 years from 2010 to 2012 of women with adenomyosis were diagnosed by transvaginal sonography and confirmed histologically. Subjects divided into women who were treated by adenomyosis resection (with/without Osada’s technique) and who were underwent hysterectomy. Results: After the surgery, as many as 40 patients (81.63%) did not feel any pain (VAS 0), and 9 patients (18.37%) still felt pain. For the fertility outcome, we had 8 patients (20.51%) getting pregnant naturally without any fertility intervention. Two patients (5.13%) had successfully conceived by IVF. According to the type of surgery, from 8 natural pregnancy, 7 patients (87.50%) was underwent conventional resection of adenomyosis and 1 patients (12.50%) underwent Osada’s procedures. Two patients who were conceived by IVF, both of them were underwent Osada’s resection. Conclusion: Adenomyosis resection both conservative or Osada’s procedures actually has a better outcome for relieving pain; therefore, some patients can still have a child. Keywords: adenomyosis resection, conventional resection, infertility, Osada’s procedure
Basal follicle stimulating hormone and leptin on the day of hCG administration predict successful fertilization in in vitro fertilization Hestiantoro, Andon; Wiweko, Budi; Purwaka, Robert H.
Medical Journal of Indonesia Vol 25, No 1 (2016): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (398.786 KB) | DOI: 10.13181/mji.v25i1.1215

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Background: Successful pregnancy in in vitro fertilization (IVF) program depends on multiple factors. This study aimed to determine whether age, body mass index (BMI), basal follicle stimulating hormone (FSH), estradiol, and leptin on the day of trigger ovulation with human chorionic gonadotropin (hCG) might be used as predictor for successful oocyte fertilization in in vitro fertilization (IVF) program.Methods: This is a cross sectional study conducted in Yasmin Fertility Clinic, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Forty participating patients underwent IVF program, excluding smokers, patients with diabetic, morbid obesity, and severe oligospermia or azoospermia. Age, BMI, basal FSH, estradiol, leptin on the day of hCG administration, oocyte count on oocyte retrieval, the number of mature oocyte, and fertility rate were analyzed using bivariate and multivariate analysis to determine which eligible factors play role in predicting the successful of fertilization.Results: Significant correlation was found between basal FSH level and serum leptin/oocyte ratio on the day of hCG administration with successful fertilization. We found probability formula as follows: 1/(1+exp –(6.2 - 0.4(leptin serum/oocyte ratio) - 0.8(basal FSH)), with 77.8% sensitivity, 77.8% specificity, and AUC levels of 85.6% indicating strong predictability. Probability of successful fertilization related to basal FSH level of 5.90 mIU/mL and leptin serum/oocyte ratio of 3.98.Conclusion: The formula consisting of basal FSH and leptin serum/oocyte ratio on the day of trigger ovulation was capable in predicting the probability of successful fertilization in IVF procedure.
Low estradiol levels escalate menopausal symptoms leading to mild cognitive impairment in postmenopausal women Hestiantoro, Andon; Jasirwan, Shanty Olivia; Wiwie, Martina; Shadrina, Amalia; Ibrahim, Nurhadi; Astuti, Brilliant Putri Kusuma
Medical Journal of Indonesia Vol 28, No 1 (2019): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (291.849 KB) | DOI: 10.13181/mji.v28i1.2447

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BACKGROUND Women in menopause experience dramatic alterations in gonadal hormone concentrations, including diminished estradiol levels. It has been hypothesized that these hormonal changes may be responsible for the occurrences of menopausal symptoms, such as hot flushes, sleep disruption, night sweats, and irritability, as well as mild cognitive impairment (MCI) in postmenopausal women. Therefore, this study was aimed to determine if there is any association between hormonal changes and menopausal symptoms, including MCI in postmenopausal women.METHODS A total of 245 postmenopausal women were recruited for this cross-sectional study and classified into 2 groups; MCI and non-MCI groups. Diagnosis of MCI was made using the modified Petersen criteria. Variables such as subjects’ age, duration of menopause, menopausal symptoms, anthropometric status, hormone levels, and cognitive status were assessed and statistically analyzed.RESULTS Of the 245 subjects enrolled in this study, 53.9% had MCI. Multivariate analysis found that sleep disruption and estradiol levels were independent risk factors of MCI in postmenopausal women. No significant correlation was found between menopausal symptoms and estradiol concentration.CONCLUSIONS Low estradiol levels were associated with higher risks of experiencing menopausal symptoms and MCI. Sleep disruption and estradiol levels were the most influential factors in the development of MCI in postmenopausal women.
Internet Based Infertility Information in Bahasa Indonesia Quality Survey Hestiantoro, Andon; Kusumaningtyas, Intan
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.503 KB) | DOI: 10.32771/inajog.v6i1.754

Abstract

Objective: To assess the quality of websites providing informationon infertility and its management in Bahasa.Methods: Differences between website types and affiliates wereassessed for the credibility, accuracy and ease of navigation usingpredefined criteria. We used Google search engine with the keyword"infertilitas" and we assessed 50 websites in Bahasa that relates withinfertility.Results: The content credibility for most of the sites has adequatescore with range of score 60 to 80 for 68% sites. Content accuracyfor most of the sites have scores more than 60, with 24% or 12sites with scores 60 to 80 and 44% or 22 sites have scores above80. The ease of navigation for most of the sites, 47 sites or 94%has scores more than 60.Conclusion: The quality of internet based infertility information inBahasa is adequate for category credibility, accuracy and ease ofnavigation.[Indones J Obstet Gynecol 2018; 6-1: 28-33]Keywords: bahasa, infertility, information, internet, quality
Maternal Age, Abortion and Aneuploidy Hestiantoro, Andon
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (57.887 KB) | DOI: 10.32771/inajog.v4i2.74

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Co-Authors A. Abadi Abdullah, Muhammad Raoul Taufiq Achmad K. Harzif Achmad K. Harzif Achmad Kemal Achmad Kemal Harzif Agnes Stephanie Harahap Aldri Frinaldi Ali Baziad Andrew Kurniawan Ario Legiantuko Asmarinah Asmarinah Asmarinah Astuti, Brilliant Putri Kusuma Bagastoro, Aswan Baidah, Priska A Betaria Putri Bram Pradipta Budi Wiweko Caroline G. Puspita Chandra, Tania Maharani Christopher Yo, Edward Danang T. Pamungkas Dedi Afandi Dick F. Swaab Eka R. Gunardi Elisia Atnil Eliza Mansyur Fadilah Fadilah, Fadilah Fakhri, Aldithya Faradina, Anindita Abigail Febriyeni, Febriyeni Ferry Sandra Gita Pratama Hari Kurniawan, Riyan Hartanto Bayuaji Herbert Situmorang Herbert Situmorang Indah S. Widyahening Intan Kusumaningtyas Intan Kusumaningtyas Irzanti, Alisha Nurdya Iswara, Raja AFW. Iswara, Raja AW. Jasirwan, Shanty Olivia Kanadi Sumapradja Kemal, Achmad Legiantuko, Ario Martina Wiwie Setiawan Nasrun Maryam Ulfa Mila Maidarti Muharam Natadisastra Muharam Natadisastra, Raden Muharam, Muharam Muharam, R Muharam, Raden Naylah Muna Nurdya Irzanti, Alisha Nurhadi Ibrahim Oki Riayati Ponco Birowo Prasetya, David Eka Priska A Baidah Puspita E. Wuyung Raymond R. Tjandrawinata Raymond Surya Retno A. Werdhani Ririn Rahmala Febri Robert H. Purwaka, Robert H. Saraswati, Jaya Shadrina, Amalia Silvana, Vita Suryoadji, Kemal Akbar Tita Yuningsih Tommy Dharmawan Trinovita Andraini Tulandi, Togas Vita Silvana Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Yo, Edward Christopher Yudianto B Saroyo Yuli Budiningsih