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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 36 Documents
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Search results for , issue "Volume. 2, No. 3, July 2014" : 36 Documents clear
Recurrence-Free Survival Stage IB1-IIA2 Intermediate Risk Group (Based on Kartu Delgado) Cervical Carcinoma after Radical Surgery and Adjuvant Radiotherapy: Kesintasan Bebas Kekambuhan Kelompok Risiko Menengah Berdasarkan Kartu Delgado pada Kanker Serviks Stadium IB1-IIA2 Pascaoperasi Radikal dan Radioterapi Ajuvan Andi Friadi; Sigit Purbadi; Budiningsih Siregar; Bambang Sutrisna
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.542 KB) | DOI: 10.32771/inajog.v2i3.397

Abstract

Objective: To evaluate the benefits of adjuvant radiotherapy (ART) based on Kartu Delgado (simple form of Gynecologic Oncology Group (GOG) scoring system) aimed at women with early stage cervical cancer after radical surgery. Method: Fifty patients were enrolled for this study. Twenty one patients from 2011-2012 were given ART following surgery based on their Kartu Delgado score from as follows: score <120 were designated for observation; score >120 were given ART. Their score and recurrence were compared with 29 patients who were treated in 2009-2010 (based on single prognostic factor). Result: We observed eighteen recurrences for the duration this study. Thirteen patients from the period of 2009-2010 and five patients from the period of 2011-2012. Most recurrences occurred in patients from 2009-2010 with score > 120 but were not designated ART. Two-years recurrence-free survival (RFS) for subjects with score <120 who were designated observation was 76.23% while for score >120 with ART was 64.29%. Conclusion: Adjuvant radiotherapy given based on Kartu Delgado reduced the number of recurrences in women with stage IB-IIA cervical cancer after treated by surgery. Keywords: cervical carcinoma, intermediate risk, prognostic factor, radical hysterectomy
Prevalence of High-Risk Human Papillomavirus (HPV) among Negative Visual Inspection of Acetic Acid (VIA): Prevalensi Human Papillomavirus (HPV) Risiko Tinggi pada Hasil Inspeksi Visual dengan Asam Asetat (IVA) yang Negatif Tofan W Utami; Muhammad F Aziz; Gatot Purwoto; Alexander AW Peters; Gert J Fleuren; Vivian Spaans; Sigit Purbadi
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (110.835 KB) | DOI: 10.32771/inajog.v2i3.398

Abstract

Objective: Persistence of high-risk HPV infection is known to be the major cause of cervical cancer. It is important to differentiate the genotype of HPV infection, whether it is high, intermediate or low risk. The aim of this study was to assess the prevalence of high-risk HPV types among Indonesian women with negative VIA. Method: We analyzed cervical swabs from 1,214 patients with negative VIA. By using INNO-Lipa HPV DNA test, we detected the HPV DNA and its genotype. Result: From the 1,214 women with negative VIA, 48 (3.95%) samples were confirmed to have positive HPV DNA by using PCR and electrophoresis. However, hybridization test were not able to detect HPV genotypes in 9 samples. These 9 samples were tested again with PCR and electrophoresis and resulted in negative HPV DNA. Among the remaining 39 samples (3.21%), we detected 19 types of HPV, consisting of 13 types of high-risk HPV, 5 types of low-risk HPV, and 1 type of unknown HPV (type X). Conclusion: Among patients with negative VIA, 3.21% was found to be positive for HPV DNA. From this percentage, the prevalence of high-risk HPV is higher than the low-risk and unknown HPV. Therefore we cannot ignore results of negative VIA, particularly in highrisk group, because there is a slight possibility that presence of HPV can be identified, especially the high risk ones which have a tendency to be persistent. We support the importance of HPV DNA test as cervical cancer screening method. Keywords: cervical cancer, high-risk HPV, negative VIA
Ovarian Malignancy Prediction by Gatot Purwoto (GP) Score, Risk Malignancy Index (RMI), and Frozen Section in Young Age: Prediksi Keganasan Ovarium dari Skor Gatot Purwoto (GP), Risk Malignancy Index (RMI), dan Potong Beku pada Usia Muda Liva Wijaya; Fitriyadi Kusuma
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (145.8 KB) | DOI: 10.32771/inajog.v2i3.399

Abstract

Objective: To know the diagnostic value of a scoring system taken before surgery and frozen section in young-aged patients with suspected malignancy. Using that result, we can also investigate whether frozen section gives additional value to clinical scoring system. Method: This study is a diagnostic test. This study was carried out by accessing RSCM’s medical record from 2006-2011. From 437 patients suspected of ovarian malignancy, we included 157 patients due to age. Result: Diagnostic value of GP score are 77%, 49%, 61%, 68%, 63%, while RMI are 69%, 49%, 58%, 45%, 59%, (sensitivity, specificity, positive predictive value, negative predictive value, and accuracy respectively). Diagnostic value of frozen section in patients with suspected malignancy using GP score >4 are 81.7%, 87.2%, 90.7%, 75.6%, 83%, while in patients with RMI 200 are 81%, 87%, 89%, 77%, 83% (sensitivity, spesificity, positive predictive value, negative predictive value, and accuracy respectively). Conclusion: Gatot Purwoto score and RMI have good diagnostic value in proving malignancy in young age. Its predictive value will be increased by frozen section. Keywords: frozen section, gatot purwoto score, ovarian malignancy, RMI, young age
Uterine Perforation on Invasive Hydatidiform Mole during EMACO Treatment: Perforasi Uterus pada Mola Hidatidosa Invasif saat Tatalaksana EMACO Bram Pradipta; Andrijono Andrijono; Sigit Purbadi; Tofan W Utami
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (213.341 KB) | DOI: 10.32771/inajog.v2i3.400

Abstract

Objective: Improving skill and knowledge to recognize and manage a rare case of uterine perforation on invasive hydatidiform mole. Method: Case report. Result: A 42 years old Indonesian woman, Parity 2 Abortus 2 with history of 2 c-sections and 2 curettage, came with chief complaint of recurrent vaginal bleeding since 4 months before admission. Patient had a history of previous curettage with indication of hydatidiform mole and recurrent bleeding with no histopathology results. On examination we found a vesicular mass with infiltration, destroying the right-front uterine corpus, size 8x6 cm with an internal echo mass. Chest x-ray showed multiple nodules in the lung. The patient, considered as low risk Gestational Trophoblastic Neoplasia patient with FIGO Score of 6, underwent chemotherapy with 2 series of methotrexate . Due to the non-declining level of -hCG, the regimen was added with EMACO. In the process of chemotherapy, the pa-tient’s-hCG declined but then she complained of major abdominal pain. Exploratory laparotomy was performed and we found a mass sized 5x5x5 cm on the right side of the uterus at the broad ligament with a rupture at the posterior part of the mass sized 0.5x0.5 cm. Upon incision of the uterus, we found a mass from the right side protruding to the isthmus of the uterus. Histopathology showed necrosis, blood and chorionic villi in myometrium corresponding to invasive mole. Patient was then given another 5 series of EMACO and her condition was unremarkable during the remaining course of treatment. Conclusion: Invasive mole treatment is determined based on the risk factors. Uterine perforation still occurred in this case regardless of the decreasing hCG level during EMACO treatment. It emphasizes the importance of clinical examination as chemotherapy responsiveness. Long-term treatment can have a good prognosis but good collaboration between the gynecologist and the patient is essential. Keywords: EMACO, invasive mole, perforation
Contraception in Malignancies: Kontrasepsi pada Keganasan Tricia D Anggraeni; Yosep Sutandar
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (111.893 KB) | DOI: 10.32771/inajog.v2i3.401

Abstract

Along with the development of cancer diagnosis and treatment, the life expectancy of women in reproductive age who suffer from cancer are also higher. Women with cancer still have the possibility to be pregnant and have a child during or after completion of therapy. Taking this into consideration, the guideline for contraception in special circumstances like this is needed. After reviewing the safety and effectiveness of contraceptive methods available for women with cancer, The Society of Family Planning urged not to use combination hormonal contraceptives (estrogen and progestin). Hormonal contraceptive use in cancer patients may increase the risk of venous thromboembolism (Level A). T380A IUD, which has a high effectiveness, reversible, long-term, and hormone-free contraception should be considered as the primary choice in patients with breast cancer (Level A). In women who received tamoxifen therapy, the use of IUD containing Levonorgestrel can be considered as a second choice (Level B) because it can decrease the proliferation endometrium. Women with anemia due to chemotherapy may be given contraceptive containing progestin (Level A). Women with osteopenia or osteoporosis after chemotherapy should avoid progestin contraceptive injection (Level A). Currently, there are no data to evaluate the risk of venous thromboembolism in progestin contraceptive use. Further information is also needed to determine the effect of the use of IUD that contains Levonorgestrel against breast cancer recurrence and the effect of hormonal contraceptives on breast cancer in women who received chest wall radiotherapy. Keywords: cancer, contraception, malignancy
Population and Contraception Djajadilaga Djajadilaga
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (63.697 KB) | DOI: 10.32771/inajog.v2i3.1078

Abstract

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Page 4 of 4 | Total Record : 36

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