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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 18 Documents
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Search results for , issue "Volume. 35, No. 3, July 2011" : 18 Documents clear
The Role of Dominant Follicular Diameter and LH in Predicting Ovulation in Cycle with Clomiphene Citrate Wiweko, Budi
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To improve diagnostic method to predict ovulation in cycle with clomiphene citrate. Method: This diagnostic research was done in RSUPN Dr. Cipto Mangunkusumo between January 2011 - October 2011 with 31 women who taking CC 50 mg/day and 30 women with normal cycle. Result: Affecting with ovulation in the two groups, it was found that in groups with CC, the follicle diameter is 24.33 ± 3.87 mm with LH 14.21 ± 7.95 IU/l, meanwhile in normal group, follicular diameter is 17.62 ± 3.45 mm with LH 14.42 ± 5.91 IU/l. Cut-off point for follicular diameter simultaneously with ovulation determined by ROC curve was found in 24.33mm (AUC 0.67, sensitivity 0.64, specificity 0.56), meanwhile the cut-off for LH is 14.40 IU/l (AUC 0.61, sensitivity 0.57, specificity 0.43). Conclusion: In group with CC, ovulation occurred in bigger follicular diameter than normal cycle, while LH does not different significantly. [Indones J Obstet Gynecol 2011; 35-3: 128-9] Keywords: clomiphene citrate, follicular diameter, luteinizing hormone
Correlations of Chronic Periodontitis with Preeclampsia and Fetal Birth Weight Yoseffin, Octaviana
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: Preeclampsia is the main cause of maternal and perinatal mortality and morbidity one of which low birth weight. The cause of preeclampsia is multifactorial, and one of them is infection. High periodontal incidence is found in preeclampsia patients. This study is intended to find correlations between chronic periodontitis with preeclampsia and fetal birth weight. Method: The study was held in RS Dr. Hasan Sadikin Bandung, RSUD Astana Anyar and RSUD Ujung Berung in December 2010 - February 2011 using case-control study design in two groups,with 26 subjects in each group. The subjects were recorded on age, parity, gestational age, diagnosis, fetal birth weight, and periodontal status. Statistical analysis were performed using chi square test and Rank Spearman’s correlation test. Result: The characteristics of study subjects in both groups show no significant difference (p > 0.05). In the preeclampsia group, periodontitis incidence is higher which is 19 (73.08%) compared to control group which is 12 (46.15%). Based on chi square method, there is a significant correlation between periodontitis and preeclampsia with odds ratio value of 3.17 (p = 0.048; p < 0.05; 95%CI (1.19 - 8.41). Based on Rank-Spearman correlation test, there is a moderate negative correlation between periodontitis severity and with fetal birth weight with rs value of = - 0.423 and a p value of 0.002. Conclusion: Chronic periodontitis incidence is higher in preeclampsia group compared to control group. There’s a moderate negative correlation on periodontitis severity with fetal birth weight. The more severe the periodontitis, the lower the fetal birth weight. [Indones J Obstet Gynecol 2011; 35-3: 105-9] Keywords: periodontitis, preeclampsia, fetal birth weight
Etiologies of Male Infertility in Dr. Cipto Mangunkusumo Hospital, Jakarta Seno, Doddy H.
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To have description about the etiologies of male infertility in Dr. Cipto Mangunkusumo Hospital. Method: This was a retrospective study of 315 male infertility patients treated at the Urology Department Dr. Cipto Mangunkusumo Hospital from January 2009 to June 2011. Result: There were 78 patients excluded from the analysis due to incomplete or missing data. The available data consisted of 237 males, with a median age of 35 years old. The median duration of infertility was 4 years. Primary infertility was identified in 89.4% and secondary infertility in 10.6% of all cases. Semen analysis results were classified as normal 2.5%, aspermia 1.3%, azoospermia 41.4%, multiple abnormal parameters 38.0%, single abnormal parameter (oligozoospermia 7.6%, asthenozoospermia 6.8%, teratozoospermia 2.1%), and cryptozoospermia 0.4%. From 237 subjects, there were 39 men (15.9%) with multiple etiologies of male infertility. The most common etiology in this study was varicocele (48.5%). Other etiologies were idiopathic 27.8%, acquired factors 14.3%, obstruction 8.0%, congenital anomalies 6.3%, urogenital infection 2.5%, sexual factors 2.1%, endocrine disturbance 2.1%, no demonstrable cause 1.3%, and other abnormalities 0.8%. This study also found Y-chromosome microdeletions in 2.5% of subjects or 6/98 (6.1%) of azoospermic patients. Lifestyle factors associated with male infertility were smoking 31.6%, alcohol consumption 13.4%, hot-bathing 6.7%, and sauna 2.9%. Conclusion: There are numerous possible contributing factors of male infertility, and varicocele was the most commonly identified etiology in this study. Some of our patients were presented very late for infertility treatment, therefore prompting the necessity to increase general awareness of male infertility in the society. [Indones J Obstet Gynecol 2011; 35-3: 130-4] Keywords: azoospermia, varicocele, risk factor
Characteristics of Patients with Hypertension in Pregnancy at Sanglah Hospital Sutopo, Hendrik
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (26.284 KB)

Abstract

Objective: To report the profile of patients with Hypertension in Pregnancy (HIP) at Sanglah Hospital Denpasar from 2009 to 2010. Method: A retrospective descriptive study from all HIP patients at Sanglah Hospital Denpasar, Bali during January 2009 to December 2010. Result: The prevalence of HIP at Sanglah Hospital was 9.32%, which consisted of 1.82% gestational hypertension, 0.19% chronic hypertension, 1.36% mild preeclampsia, 4.70% severe preeclampsia, 0.43% superimposed preeclampsia, and 0.82% eclampsia. From all of HIP cases, we found that the majority were nulliparous (47.23%), primipaternal (53.1%), and had hypertension at term (51.9%). Most of the cases were found at maternal age > 35 years (14.62%), followed by age < 20 years (13.47%). Most of them also had Ante Natal Care (ANC) frequency ≥ 4 times (69.09%), and had their ANC done by a midwife (52.76%) and followed with an obstetrician (40.81%). The majority of the cases were referral cases (62.39%) mostly by midwives (22.45%). From all of the cases, we found that total preterm labor was 35.14%, perinatal mortality was 9.32% and maternal mortality was 1.16%. Conclusion: The prevalence of HIP at Sanglah Hospital was higher than previous years. Most of them had already had ANC done by health care providers, who were mostly midwives and obstetricians. Therefor, the quality of ANC seems to need an improvement by having an earlier referral system, so cases can be treated earlier. [Indones J Obstet Gynecol 2011; 35-3: 97-9] Keywords: hypertension in pregnancy, preeclampsia and eclampsia, descriptive
The Rise of Inhibin A Serum Level in Preterm Labor Haribudiman, Oky
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: The purpose of this study was to measure inhibin A serum level in women with preterm delivery, thus determining any correlation between inhibin A serum and gestational age in preterm delivery. Method: The design of our study was cross sectional with 36 subjects who came to Dr. Hasan Sadikin Hospital, Bandung and six satellite hospitals in July-August 2011 and met inclusion-exclusion criteria. Inhibin A serum level was measured with ELISA. Inhibin A serum level in preterm labor and was compared using independent t test, and correlation between inhibin A serum level and gestational age in patients with preterm labor was calculated using Pearson correlation test. Result: Characteristics test in both groups showed that both are homogeneous and comparable. The mean inhibin A serum level in preterm labor was higher (845.733 pg/ml) compared with preterm gestation (568.203 pg/ml) (p = 0.025). There was a significant correlation between inhibin A serum level and gestational age in preterm labor (p = 0.023) with a correlation coefficient of 0.38, indicating a moderate positive relationship. Conclusion: Inhibin A serum level in preterm labor was higher than preterm pregnancy. In preterm labor, inhibin A serum level increases with gestational age. [Indones J Obstet Gynecol 2011; 35-3: 110-4] Keywords: preterm delivery, inhibin A serum level
Laparoscopic Robotic Surgery in Gynecology Hadisaputra, Wachyu
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know the development and application of robot assisted laparoscopy in gynecology. Method: Literature review. Result: Laparoscopy procedure has been widely used since the last three decades where minimally invasive surgery cases and demands increase in urology, cardiac surgery, general surgery, and particularly, gynecology. To date, laparoscopy has developed into robot-assisted laparoscopy due to needs of precise dissection of delicate structures, procedures which requires sophisticated technique, and surgeon’s fatigue through the laparoscopy procedure. There are three robotic system which are commercialized and had been approved by FDA: AESOP, ZEUS, and Da Vinci, the latest robotic system which is used worldwide nowadays. There are advantages of robotic systems and conventional laparoscopy to open surgery laparotomy, such as diminished morbidity rate; less esthetical incisions; decreased post and intra operative blood loss, postoperative pain, use of pain medication, less cosmetic problems, and shorter length of hospital stay. Advantages of robotic surgery compared to conventional laparoscopy and laparotomy; include improved dexterity, more precise and accurate articulation, reduced tremor and surgeon’s fatigue, and better visualization of the operating field because of 3D image. Robotic system has drawbacks such as limited area of surgery field in trocar-placing to avoid collision of the robotic arms, longer operative time, and a higher cost. Conclusion: The major drawback of robot-assisted laparoscopy is in the term of cost; because of the high cost of robotic system; which could be overcome by a lower morbidity rate, less incisional aesthetic problem, less total intra operative blood loss, decreased demand of analgesics post operative, and shorter length of hospitalization stay and recovery time; as compensation of the high cost of robotic system. Further researches to study about the learning curve of robotic laparoscopy to achieve a faster operative time are needed. A longer operative time in robotic system can be anticipated with accurate simulation training in robotic system. There is also a need for further researches to discuss the total peri-operative cost. [Indones J Obstet Gynecol 2011; 35-3: 146-50] Keywords: laparoscopy, robotic system, robot-assisted, Da Vinci system, learning curve, gynecology
Antioxidant Milk Supplementation in Pregnancy: A Study of Retinol Binding Protein and Angiogenic Factors in Preeclampsia Hutabarat, Martina
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objectives: To assess the role of retinol supplementation in the process of angiogenesis in preeclampsia. Methods: The research was a double blind randomized clinical trial conducted Dr. Cipto Mangunkusumo Hospital outpatient clinic since January 2009 - December 2010. Samples were analyzed in Prodia Laboratory and Showa University in Tokyo, Japan. Subjects were tested in trimester 1, 2 and 2 weeks after delivery. During pregnancy subjects were given pregnancy milk supplements available on the market which had and that has been retinol fortified. Bivariate and multivariate analysis were performed of which retinol milk feeding, retinol binding protein (RBP) level, and level of angiogenic factors as independent variables and preeclampsia acted as the dependent one. Results: One hundred four study subjects were divided into a control group of 55 and treatment of 49. Incidence of preeclampsia in this study was is 8.7% from which 8 persons (14.5%) came from the control group and 1 person (2%) from the treatment group. Characteristics of the two groups were equivalent. RBP levels obtained in the treatment group was lower than the control group, while in the subjects with preeclampsia the RBP level was higher than the group without preeclampsia. Correlation between the level of RBP with angiogenic factors showed no significant relationship except for the level of PlGF (p=0.036) which had a weak correlation (r=0.206). The level of angiogenic factors in the treatment group showed lower result than the control group whereas among the subjects with preeclampsia angiogenic factor levels were always higher than without preeclampsia. With multivariate analysis we found that significant factors associated with preeclampsia was sFlt-1 levels (p=0.004) and sFlt-1/PlGF ratio (p=0.017). Conclusions: Providing milk supplements can reduce the levels of retinol (RBP), and antiangiogenic factors, but does not significantly increase proangiogenic factor level. Assuming there is no problem with the process of angiogenesis provision of retinol-fortified milk can reduce the incidence of preeclampsia. However, further research with a larger scale is needed. [Indones J Obstet Gynecol 2011; 35-3:100-4] Keywords: retinol-fortified milk, RBP level, sFlt-1 level, sEng level, PlGF level, preeclampsia
Comparison of Macrophage Migration-Inhibitory-Factor (MIF) Serum Level between 28 - 36 Weeks of Pregnancy and Delivery Riyanti, Novy
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To analyze the differences in Macrophage Migration Inhibitory Factor (MIF) serum level between 28 - 36 weeks of pregnancy and delivery, and determine the serum level of Macrophage MIF as a risk factor for preterm labor. Methods: The design of our study was cross sectional of 72 subjects who met the inclusion- and exclusion-criteria that came to Dr. Hasan Sadikin Hospital, Bandung and six satelite hospitals (in July - August 2011). Macrophage Migration Inhibitory Factor (MIF) level was measured with ELISA. Comparison of mean serum levels of MIF between 28 - 36 weeks of pregnancy and delivery was analyzed using the Mann Whitney test. MIF level, which is a risk factor for preterm delivery, was calculate with a prevalence ratio (PR) based on ROC curve. Results: Characteristics test in both groups showed homogeneous and comparable data. The mean levels of Macrophage Migration Inhibitory Factor (MIF) in 28 - 36 weeks of delivery was higher (54.433 ng/ml) compared with 28 - 36 weeks of gestation (31.765 ng/ml) with p ≤ 0.001. MIF levels > 37.684 ng/ml had a risk for preterm labor incidence 3.35 times greater than that of ≤ 37.684 ng/ml. Conclusion: Serum levels of Macrophage Migration Inhibitory Factor (MIF) at delivery was higher than that of at 28 - 36 weeks pregnancy. MIF levels > 37.684 is a risk factor for preterm labor. [Indones J Obstet Gynecol 2011; 35-3: 115-8] Keywords: Macrophage Migration-Inhibitory-Factor (MIF), preterm labor
Levonorgestrel Concentration in a Single Rod Implant Users for Six Months Gunardi, Eka R.
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: This research was conducted to measure levonorgestrel serum concentration Monoplant® after six months of usage. Method: Thirty healthy women, 20 - 40 years old, and after been proven for fertility, had implants on their body. Levonorgestrel serum levels were measured monthly from the first month to the sixth month. Result: Levonorgestrel serum concentration was still above 200 pg/ml until the sixth month. First month and second month serum concentration was not recorded while data for the following months were 338.9 pg/ml, 424.8 pg/ml, 320.3 pg/ml, and 337.5 pg/ml. Conclusion: Levonorgestrel serum concentration in Monoplant® users was still above contraceptive level until six months. [Indones J Obstet Gynecol 2011; 35-3: 122-7] Keywords: single rod implant Monoplant®, levonorgestrel serum concentration
Characteristics of Patients with Hypertension in Pregnancy at Sanglah Hospital Hendrik Sutopo
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (26.284 KB)

Abstract

Objective: To report the profile of patients with Hypertension in Pregnancy (HIP) at Sanglah Hospital Denpasar from 2009 to 2010. Method: A retrospective descriptive study from all HIP patients at Sanglah Hospital Denpasar, Bali during January 2009 to December 2010. Result: The prevalence of HIP at Sanglah Hospital was 9.32%, which consisted of 1.82% gestational hypertension, 0.19% chronic hypertension, 1.36% mild preeclampsia, 4.70% severe preeclampsia, 0.43% superimposed preeclampsia, and 0.82% eclampsia. From all of HIP cases, we found that the majority were nulliparous (47.23%), primipaternal (53.1%), and had hypertension at term (51.9%). Most of the cases were found at maternal age > 35 years (14.62%), followed by age < 20 years (13.47%). Most of them also had Ante Natal Care (ANC) frequency ≥ 4 times (69.09%), and had their ANC done by a midwife (52.76%) and followed with an obstetrician (40.81%). The majority of the cases were referral cases (62.39%) mostly by midwives (22.45%). From all of the cases, we found that total preterm labor was 35.14%, perinatal mortality was 9.32% and maternal mortality was 1.16%. Conclusion: The prevalence of HIP at Sanglah Hospital was higher than previous years. Most of them had already had ANC done by health care providers, who were mostly midwives and obstetricians. Therefor, the quality of ANC seems to need an improvement by having an earlier referral system, so cases can be treated earlier. [Indones J Obstet Gynecol 2011; 35-3: 97-9] Keywords: hypertension in pregnancy, preeclampsia and eclampsia, descriptive

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