Novy Riyanti
Medical Faculty of Padjajadjaran University/ Dr. Hasan Sadikin Hospital Bandung

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Comparison of Macrophage Migration-Inhibitory-Factor (MIF) Serum Level between 28 - 36 Weeks of Pregnancy and Delivery Riyanti, Novy
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (33.037 KB)

Abstract

Objective: To analyze the differences in Macrophage Migration Inhibitory Factor (MIF) serum level between 28 - 36 weeks of pregnancy and delivery, and determine the serum level of Macrophage MIF as a risk factor for preterm labor. Methods: The design of our study was cross sectional of 72 subjects who met the inclusion- and exclusion-criteria that came to Dr. Hasan Sadikin Hospital, Bandung and six satelite hospitals (in July - August 2011). Macrophage Migration Inhibitory Factor (MIF) level was measured with ELISA. Comparison of mean serum levels of MIF between 28 - 36 weeks of pregnancy and delivery was analyzed using the Mann Whitney test. MIF level, which is a risk factor for preterm delivery, was calculate with a prevalence ratio (PR) based on ROC curve. Results: Characteristics test in both groups showed homogeneous and comparable data. The mean levels of Macrophage Migration Inhibitory Factor (MIF) in 28 - 36 weeks of delivery was higher (54.433 ng/ml) compared with 28 - 36 weeks of gestation (31.765 ng/ml) with p ≤ 0.001. MIF levels > 37.684 ng/ml had a risk for preterm labor incidence 3.35 times greater than that of ≤ 37.684 ng/ml. Conclusion: Serum levels of Macrophage Migration Inhibitory Factor (MIF) at delivery was higher than that of at 28 - 36 weeks pregnancy. MIF levels > 37.684 is a risk factor for preterm labor. [Indones J Obstet Gynecol 2011; 35-3: 115-8] Keywords: Macrophage Migration-Inhibitory-Factor (MIF), preterm labor
HUBUNGAN ANEMIA DENGAN DERAJAT DISMENORE PADA MAHASISWI TINGKAT PERTAMA FAKULTAS KEDOKTERAN UNIVERSITAS PATTIMURA TAHUN AKADEMIK 2022/2023 Pratiwi, Hana Gesti; Tamalsir, Dylan; Riyanti, Novy
PAMERI Vol 6 No 1 (2024): PAMERI: Pattimura Medical Review
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/pamerivol6issue1page43-53

Abstract

Dysmenorrhea is menstrual pain that is prone to occur in teenagers, one of which is caused by anemia. Anemia is when the body has low hemoglobin levels, namely <12 g/dl. The function of hemoglobin is to bind oxygen and distribute it throughout the body. If the hemoglobin level is low, myometrial ischemia can occur, and the circulating oxygen level is also low, which can cause myometrial hypoxia, which results in menstrual pain. This study aimed to determine the relationship between anemia and the degree of dysmenorrhea in first-year students at the Faculty of Medicine, Pattimura University, for the academic year 2022-2023. This research is an analytical study with a cross-sectional approach conducted in June 2023, with a sample of 126 female students taken using the simple random sampling method. Measurement of anemia is carried out through examination of hemoglobin levels using the Easy Touch GCHb hemoglobin test tool, and measurement of dysmenorrhea is carried out using the Numeric Rating Scale (NRS) questionnaire. The research results using the Chi-Square statistical test showed no significant relationship between anemia and the degree of dysmenorrhea, with a value of p = 0.885. This research concludes that there is no relationship between anemia and the degree of dysmenorrhea in first-year students at the Faculty of Medicine, Pattimura University, Academic Year 2022-2023.
HUBUNGAN INFEKSI BACTERIAL VAGINOSIS DENGAN KEJADIAN KETUBAN PECAH DINI DI RUMAH SAKIT AL-FATAH AMBON Gutandjala, Pearly Noveliani; Riyanti, Novy; Latuconsina, Vina Z
PAMERI Vol 6 No 2 (2024): PAMERI: Pattimura Medical Review
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/pamerivol6issue2page83-92

Abstract

Background: Premature rupture of membranes (PROM) is a condition in which the amniotic membrane ruptures before labor occurs. It is one of the causes of increased maternal and neonatal morbidity and mortality. Several factors cause PROM such as maternal age, gravida status, incompetentcervix, fetal abnormality, and infections such as Bacterial Vaginosis (BV) infection. Objective: This study aims to determine the relationship between BV infection and the incidence of PROM at Al-Fatah Ambon Hospital. Methods: This research is an observational analytic type of research with acase control approach and sampling using consecutive sampling technique. Data were analyzed using the Statistical Package for the Social Science(SPSS) application. Results: The results of this study showed that out of 30 inpartum mothers, there were 18 mothers with positive BV infection (60%) and 12 mothers with negative BV infection (40%). In the group of mothers with positive BV infection, 12 people experienced PROM and 6 people did not experience PROM. In the group of mothers with negative BV infection, 3 people experienced PROM and 9 people did not experience PROM. Theresults of bivariate analysis with the chi-square test obtained p value = 0.025 and the results of the Odds Ratio analysis obtained an OR = 6.Conclusion: This study showed a significant association between BV infection and the incidence of PROM at Al- Fatah Ambon Hospital.