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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,731 Documents
 104   105   106   107   108 
Korelasi antara insulin-like growth factor - 1, anemia defisiensi besi, dan biometri janin pada kehamilan trimester III I. SUNARNO
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 3, July 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk menganalisis korelasi antara kadar IGF-1 serum ibu, anemia defisiensi besi, dan biometri janin pada kehamilan trimester ketiga. Tempat: Poliklinik Obstetri dan Ginekologi RS Dr. Wahidin Sudirohusodo dan RSIA Siti Fatimah di Makassar. Rancangan/rumusan data: Penelitian potong lintang. Bahan dan cara kerja: Dilakukan pemeriksaan kadar Hb, ferritin, dan insulin-like growth factor-1 (IGF-1) dari serum 70 perempuan hamil (34 penderita anemia defisiensi besi dan 36 normal). Kemudian dilakukan pemeriksaan biometri janin dengan ultrasonografi. Hasil: Ditemukan korelasi bermakna antara kadar IGF-1 serum ibu dengan ukuran AC dan FL janin (p = 0,0010 dan p = 0,013, berturutturut). Juga ditemukan hubungan linier positif antara kadar IGF-1 serum ibu dengan ukuran AC (r = 0,350; p = 0,001) dan ukuran FL janin (r = 0,320; p = 0,003). Anemia defisiensi besi ibu hamil trimester III berhubungan dengan janin yang mempunyai AC kecil berdasar usia kehamilan (p = 0,0450). Kesimpulan: Pada kehamilan trimester III: kadar IGF-1 serum ibu tidak berbeda bermakna antara ibu dengan anemia defisiensi besi dan normal tetapi terdapat korelasi positif antara kadar IGF-1 serum ibu dengan ukuran AC dan FL janin dan antara anemia defisiensi besi ibu dengan ukuran AC janin. [Maj Obstet Ginekol Indones 2009; 33-3:160-6] Kata kunci: kadar IGF-1, anemia defisiensi besi, biometri janin
Peran polimorfisme gen Collagen type 1 alpha 1 (COL1α1) terhadap penurunan densitas mineral tulang vertebra lumbal akseptor KB suntik DMPA A.M. TAHIR
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 3, July 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk menilai dampak pemakaian kontrasepsi suntik DMPA pada densitas mineral tulang Vertebrata Lumbal (VL.1-4) pada akseptor jangka panjang (≥ 5 tahun), dengan alat Dual Energy X-ray Absorptiometry (DEXA), sekaligus melihat apakah ada peranan faktor genetik dalam hal ini polimorfisme gen Collagen type 1 Alpha 1 (COL1α1) terhadap penurunan DMT pada akseptor KB suntik DMPA tersebut dengan teknik Polymerase Chain Reaction (PCR). Tempat: Penelitian dilakukan di Makassar antara Januari 2007 - Maret 2007 pada 31 orang akseptor suntik DMPA jangka panjang (≥ 5 tahun). Rancangan/rumusan data: Studi potong lintang. Hasil: Karakteristik sampel berdasarkan usia terbanyak: 30-35 tahun. Pendidikan SLTA (61,3%), Berat badan 40-45 kg (77,4%), Tinggi badan: 145-149 cm (38,7%), Indeks Massa Tubuh (IMT): 20,0-25,0 kg/m2 (87,1%). Ditemukan 19 orang (61,3%), dengan DMT V. Lumbal normal dan 12 orang (38,7%) dengan DMT V.L-4 dibanding V.L-1 dan V.L-2. Prevalensi polimorfisme gen COL1α1 pada penelitian ini 45,2% (32,3% G/T dan 12,9% T/T). Kejadian osteopeni lebih banyak ditemukan pada subjek yang memiliki gen heterozigot (G/T atau S/s) daripada subjek yang mempunyai gen homozigot normal (G/G atau S/S) = (p=< 0,05), dan tidak ditemukan kejadian osteopenia pada subjek yang memiliki polimorfisme gen homozigot (T/T atau s/s). Kesimpulan: Akseptor yang memiliki polimorfisme gen heterozigot (G/T atau S/s) memiliki kecenderungan untuk menderita osteopeni lebih tinggi daripada yang memiliki gen normal (G/G atau S/S). Di pihak lain, akseptor yang memiliki polimorfisme gen homozigot (T/T atau s/s) justru cenderung tidak menderita osteopeni. [Maj Obstet Ginekol Indones 2009; 33-3: 176-84] Kata kunci: DMT, DMPA, polimorfisme gen COL1α1
Pengaruh pemberian klomifen sitrat atau letrozole terhadap perkembangan folikel dan profil hormonal pada unexplained infertility S.T. HIDAYAT
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 3, July 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Membandingkan perbedaan pengaruh pemberian klomifen sitrat (CC) atau letrozole terhadap pertumbuhan folikel, keberhasilan ovulasi dan profil hormonal pada perempuan dengan unexplained infertility. Tempat: Klinik Infertilitas Subbagian Fertilitas Endokrinologi dan Reproduksi Manusia Bagian Obstetri dan Ginekologi Fakultas Kedokteran Universitas Diponegoro/RSUP Dr. Kariadi, Semarang. Rancangan/rumusan data: Uji klinik acak buta berganda tanpa kecocokan. Bahan dan cara kerja: Selama kurun waktu April 2008 - Juni 2008 didapat subjek pada kelompok CC dan 28 subjek pada kelompok letrozole. Pada hari ke-3 siklus haid seluruh subjek dilakukan pemeriksaan TVS dan pengambilan sampel darah vena untuk pemeriksaan kadar FSH, LH, dan E2 (estradiol). Mulai hari ke-3 – 7 siklus haid, masingmasing kelompok mendapat CC 50 mg atau letrozole 2,5 mg per hari. Pada hari ke-8 dan 12 siklus. Subjek mengalami pemeriksaan ulang. Jika pada hari ke-12 siklus belum terjadi ovulasi, TVS dilanjutkan hingga hari ke-14, 16, dan 18 siklus. Hasil: Pada kelompok CC didapatkan hari ke-8 dan ke-12 siklus, diameter folikel lebih besar. Diameter folikel telah mencapai 18 mm pada hari ke-8 dan > 25 mm pada hari ke-12 siklus, seluruhnya berupa folikel matur multipel, terjadi ovulasi mulai pada hari ke-12 – 13 siklus haid, kadar FSH, LH, dan E2 lebih tinggi baik pada hari ke-8 maupun ke-12 siklus. Pada kelompok letrozole didapatkan seluruh objek berupa folikel matur tunggal, ovulasi terjadi pada hari ke 14 - 15. Kesimpulan: Pada kelompok CC didapatkan; diameter lebih besar, seluruhnya berupa folikel matur multipel, terjadi ovulasi lebih awal, kadar hormon FSH, LH, E2 lebih tinggi. Pada kelompok letrozole didapatkan seluruhnya berupa folikel matur tunggal, ovulasi terjadi mulai pada hari ke-14 dan 15 siklus. [Maj Obstet Ginekol Indones 2009; 33-3: 185-94] Kata kunci: klomifen sitrat, letrozole, induksi ovulasi, superovulasi, diameter folikel, FSH, estradiol, E2
Pengaruh pemberian clomiphene citrate atau letrozole terhadap folikel, endometrium dan lendir serviks (uji klinik pada perempuan infertil dengan gangguan ovulasi WHO II) J. DEWANTININGRUM
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 3, July 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk membandingkan perbedaan diameter folikel, jumlah folikel matur, kualitas endometrium, kualitas lendir serviks dan keberhasilan ovulasi antara pemberian clomiphene citrate (CC) atau letrozole. Bahan dan cara kerja: Uji acak terkontrol buta berganda dengan desain paralel tanpa matching mulai periode 1 September 2007 sampai 31 Januari 2008 di RSUP Dr. Kariadi Semarang. Jumlah sampel adalah 40 perempuan infertil dengan gangguan ovulasi WHO II terbagi masingmasing 20 subjek pada kelompok CC dan kelompok letrozole dengan randomisasi blok. Variabel bebas adalah CC (50mg/hari) dan letrozole (2,5mg/hari) diberikan pada siklus haid hari ke-3 sampai 7. Variabel tergantung adalah diameter folikel, jumlah folikel matur, kualitas endometrium, kualitas lendir serviks dan keberhasilan ovulasi. Analisis data untuk uji beda 2 kelompok tidak berpasangan dengan chi square, t test, Mann Whitney dan uji korelasi Lambda dan Spearman, dengan derajat kemaknaan p
Hubungan pengetahuan dan sikap bidan tentang rujukan kasus obstetri dengan ketepatan rujukan: suatu studi analisis verifikatif di Kabupaten Bantul, Yogyakarta Heni Puji Wahyuningsih
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Memperoleh informasi mengenai ketepatan rujukan kasus obstetri oleh bidan di Kabupaten Bantul, Yogyakarta. Metode: Rancangan penelitian ini menggunakan metode survei eksplanatoris terhadap pengetahuan dan sikap bidan tentang rujukan kasus obstetri dengan ketepatan rujukannya. Data dikumpulkan secara potong silang, dengan rancangan retrospektif (kasus-kontrol). Subjek penelitian 109 responden. Analisis data menggunakan prosedur analisis uji t, Mann-Whitney, uji Chi-Kuadrat, uji korelasi VCramer dan analisis regresi logistik ganda. Hasil: Pada penelitian ini didapatkan bahwa terdapat perbedaan skor pengetahuan berdasarkan rujukan tepat vs tidak tepat (81,2 vs 63,6; p
Profile of pregnant women with tuberculosis at the tuberculosis policlinic of the eradication of tuberculosis, Tuberculosis Foundation, Baladewa Central Jakarta Laksmi Maharani
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know profile of pregnant women with tuberculosis at PPTI Baladewa polyclinic Jakarta, to evaluate impacts of tuberculosis medicinal treatment on pregnancy and to know the obstacles of pregnant women to look for tuberculosis treatment. Methods: Subjects were all pregnant women with tuberculosis and received tuberculosis treatment at polyclinic of PPTI Baladewa from January 2006 - December 2007. We reviewed medical record and did home visitation to fill questioners. Results: All subjects were in reproductive age and most of all were low socio-economic group. Pulmonary tuberculosis was found in 88.2% cases and Extrapulmonary tuberculosis in 11.8% cases. We found 29.4% relapse cases and 11.8% multi-drug resistance. Sputum examination with a smear positive for acid fast-bacillus was found in 52.9% cases. There was abnormality for all chest x-rays. The third most frequently symptoms were cough more than two weeks (88.2%), weight loss (88.2%) and anorexia (82.4%). Average time for the patients to look for treatment was 50.71 ± 31.2 days. The patients need more time because most of the symptoms are also present in pregnancy, the patients know absolutely nothing about TB and healthcare provider didn’t examine carefully. Treatment for the patients was given immediately without considering the gestational age. Conclusion: No harmful effect was observed for neonates even if the drugs were given in the first trimester of pregnancy. [Indones J Obstet Gynecol 2009;33-4:210-5] Keywords: profile, pregnancy, tuberculosis
Effectiveness of psychoeducation of postpartum depression (a study in health services in subprovince Nias, North Sumatra) Yafeti Nazara
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To evaluate the effectiveness of psycho-education intervention which is given to postpartum mothers in preventing the existence of postpartum depression and its relation to age, parity, occupation, education and family support. Methods: This research used a quasi experimental with post test only design. Research was implemented at public hospital of Gunung Sitoli and five community health centres in Sub-Province of Nias taken by random on since May - July 2006. There were 85 mothers with normal childbirth as samples. They were accompanied by their husband, condition of mothers and their babies were healthy without any complication. This research used an Edinburg Pascasalin Depression Scale questionnaire as instrument and psycho- education intervention was given with a booklet as media. Results: 85 subjects were included, 40 were intervention group and 45 control group. This research showed that psycho-education intervention was effective significantly (p= 0,001), Odds Ratio (OR): 5,924 (95 % CI : 2,081-16,868) to prevent the postpartum depression occurrence. The most dominant variable in effectiveness of psycho-education intervention is family support variable with pvalue is p = 0,001, OR : 80 (95 % CI : 6,069-1054,570). Conclusion: Psycho-education intervention is very effective for preventing the postpartum depression occurrence after controlled by family support factor. [Indones J Obstet Gynecol 2009;33-4:216-23] Keyword: psycho-education, postpartum depression, family support.
Serum Anti Mullerian Hormone level as ovarium response predictor at women received ovarium stimulation invitro Soegiharto Soebijanto
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To evaluate clinical value of basal anti-Mullerian Hormone level as predictor of ovarian response to stimulation in women following in vitro fertilization program; compared with Follicle Stimulating Hormone (FSH), estradiol and basal antral follicle. Method: Research was conducted in Yasmin Clinic Cipto Mangunkusumo Hospital as tertiary referral center for reproductive health and in vitro fertilization. Infertile patients which going to undergo controlled ovarian hyper stimulation cycle for in vitro fertilization were checked for basal FSH level, estradiol level, AMH level and amount of basal antral follicle. We were divided the sample into two categories; poor responders and good responders. Statistical analysis using ANOVA was done to evaluate demographic data and Receiver Operator Characteristic area under curve (ROCAUC), and to analyze whether AMH was more superior than the other 3 predictors and to get the cut off point for AMH level. Result: We have collected 22 patients data; 14 were categorized as good responders and 8 were bad responders. Mean AMH value in the good responders group was 4.46±1,01 and in the poor responders group was 1,35±0,96, with p 0,000. According to ROCAUC, AMH is a good predictor for good ovarian response in patient who are a good responders (AUC 0,821), compared to the other three predictors (FSH, E2 and basal antral follicle). Anti Mullerian Hormone cut-off point level is 3, which means value
The effect of letrozole and clomiphen citrate in mature follicle count, ovulation and endometrial thickness in unovulated cycle women Sri Maryati
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know the efficacy of letrozole and clomiphene citrate for ovulation induction in anovulation women. Method: During the period of January-October 2007, 44 women who met criteria for an ovulation age 18-35 years old, were done anamnesis, physical examination, USG, and hormonal analysis (FSH, LH, E2, Progesterone and Prolactin). All participants were divided into letrozole and clomiphene citrate group. For the letrozole group received 2,5 mg letrozole daily on 3th until 7th day menstrual cycle. The clomiphene citrate group received 50 mg twice a day, on 3th until 5th day menstrual cycle. On 12th menstrual cycle the ultrasound examination was perfomed to measure number of mature follicle and endometrial thickness. On the 18th day of menstrual cycle, ultrasound was perfomed to evaluate ovulation. Result: There was significant difference between letrozole group and clomiphene citrate group (p=0.04) with the number if follicles in letrozole group is 1.08 (±0.27), in clomiphene citrate group 1.40 (±0.51). There was no significant different in mean of follicle size (p=0.32). Ovulation in both groups was not significantly different (p=0.53), 59% in letrozole group and 68% in clomiphene citrate group. There was significant difference in endometrial thickness, mean of endometrial thickness in letrozole group is 8.77 mm (±2.32 mm) and in clomiphene citrate group 6,66 mm (±2.34 mm) (p
Cytology of uterine cervix after one year use of Depo Provera and Cyclofem Jan Pieter Kambu
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: The objective was to examine cervical cytology findings from conventional Pap smear examination in Depo-Provera® and Cyclofem® acceptor in one-year period. Method: The study design is descriptive observational involving 35 Depo-Provera® and 35 Cyclofem® acceptor. We follow up their cytology findings prospectively. This study was conduct in FER and gynecology clinics at Dr. Kariadi Hospital Semarang also at Halmahera and Ngesrep public health service. The subjects were women, aged 20 - 40 years old who chosen Depo-Provera® and Cyclofem® as their contraceptive methods. This study began on December 2006, all subjects who met inclusion criteria underwent initial cytology screening. On December 2007, and there were 70 subjects. They underwent cytology examination at month sixth (simultaneously with third Depo-Provera® injection and seventh Cyclofem® injection) and at month twelve (simultaneously with fifth Depo-Provera® injection and thirteenth Cyclofem® injection). Distribution frequency was analyzed using univariate analysis and data shown as mean and standard deviation whereas bivariate analysis was conduct with X2 and t-test. Cytology examination was conduct in anatomy pathology laboratory at Medicine Faculty, Diponegoro University/Dr. Kariadi Hospital, Semarang. Result: Inflammation rates tend to increase on Depo-Provera® group compare to Cyclofem® group. At first cytology result there is no difference between two groups, it suggest that both groups had same baseline characteristic. Thereafter, at second and third examination, Depo-Provera® group significantly showed higher inflammation and dysplasia rates compare to Cyclofem® group. Conclusion: After one-year period, there was difference on cervical cytology results that is inflammation rates which higher on Depo- Provera® acceptor compare to Cyclofem®. [Indones J Obstet Gynecol 2009; 33-4: 233-8] Keywords: pap smear, Depo-Provera®, Cyclofem®, Pap smear on hormonal contraception

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