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Radioterapi & Onkologi Indonesia
Published by Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia
ISSN : 20869223     EISSN : -     DOI : -
Core Subject : Health, Science, Education,
Education Health Professions Medicine & Pharmacology Physics Other
Majalah Radioterapi & Onkologi Radiasi Indonesia (Journal of the Indonesian Radiation Oncology Society) dengan ISSN 2086-9223, satu-satunya majalah dalam bidang Onkologi Radiasi di Indonesia, merupakan majalah di bawah penerbit Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI). Majalah ini rutin diterbitkan sejak tahun 2010 dengan frekuensi terbitan 2 kali dalam setahun.
Arjuna Subject : -
Articles 5 Documents
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Search results for , issue "Vol 12, No 2 (2021): VOLUME 12 NO.2 JULY 2021" : 5 Documents clear
The effect of bone radiation on hematopoiesis: A literature review Rendhy Tito Apreza; Soehartati A. Gondhowiardjo
Radioterapi & Onkologi Indonesia Vol 12, No 2 (2021): VOLUME 12 NO.2 JULY 2021
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32532/jori.v12i2.135

Abstract

Over time, external radiation techniques have continued to evolve so that they can be used totreat bone malignancies for curative, postoperative adjunct, and metastases purposes. However,in the bone, there is the bone marrow that is sensitive to radiation. Even sublethal doses cancause bone marrow microenvironment deficits, including a decrease in hematopoietic cells.There is a complex relationship between radiotherapy (RT) and the hematopoietic system.Acute radiation injury usually manifests as cytopenia: anemia, neutropenia, andthrombocytopenia. Several potential mechanisms regarding the effects of radiotherapy on bonemarrow, including direct damage to the hematopoietic stem cells (HSC), lead to decreasednumber and function. This literature review will discuss hematopoiesis, the effect of boneradiation on hematopoiesis, and its mechanisms.
Role of Radiation in Metachronous Multicentric Giant Cell Tumor of Bone: A Case Report Nana Supriana; David Andi Wijaya
Radioterapi & Onkologi Indonesia Vol 12, No 2 (2021): VOLUME 12 NO.2 JULY 2021
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32532/jori.v12i2.141

Abstract

Introduction: Giant cell tumor of the bone (GCTB) is a rare benign locally aggressive tumor. Surgical resection whenever feasible is treatment of choice for GCTB. Case Presentation: In this report the author will review a case of well locally controlled postoperative GCTB on left ilium bone after adjuvant radiation was delivered, with metachronous lesion on right calcaneus and distal tibia which appeared 9 years later.Conclusions: Radiation either in adjuvant setting or definitive in unresectable lesion could bring adequate local control.
Dosimetric Parameter Analysis of Stereotactic Radiosurgery on Vestibular Schwannoma with Intensity-Modulated Radiotherapy Step-and-Shoot, Volumetric-Modulated Arc Therapy and Helical Tomotherapy Soehartati A. Gondhowiardjo; Aurika Sinambela; Handoko Handoko; Arie Munandar; Wahyu Edy Wibowo; Sri Mutya Sekarutami; Angela Giselvania
Radioterapi & Onkologi Indonesia Vol 12, No 2 (2021): VOLUME 12 NO.2 JULY 2021
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32532/jori.v12i2.140

Abstract

Introduction: SRS is a non-invasive modality in management of vestibular schwannoma. There is limited study comparing dosimetric parameters between three techniques SRS in vestibular schwannoma cases, thus IMRT Step and Shoot (IMRT-SS), VMAT, and Helical Tomotherapy (HT). Aim: To compare the dosimetry parameters on SRS among IMRT-SS, VMAT, and HT techniques on Vestibular ScwhanomaMethod: Treatment planning with IMRT-SS, VMAT, and HT on eleven CT plan data for schwannoma vestibular cases. The marginal dose is 12 Gy with single fraction. Results: Mean tumor size was 8.23 cm + 5.08 cm3. No significant difference were found in the mean CI, GI, V100%, and V50% among three techniques. There was no significant difference in maximal dose to brainstem, ipsilateral cochlea, chiasma opticum, ipsilateral and contralateral optic nerve between the three techniques. There was significant difference of maximum dose on contralateral cochlea between IMRT-SS and VMAT techniques. The longest beam-on time was obtained with HT technique (1209,18 +390,20 second), followed by IMRT-SS technique (665,05 + 73,40 second), and the shortest was with VMAT technique (362,87 + 24,55 second). There was significant difference in mean MU and beam on time between three techniques. Conclusion: VMAT technique could be an option for SRS for vestibular schwannoma cases to provide conformity and gradient index as well as IMRT-SS and HT techniques, with better sparing to contralateral cochlea compared with IMRT-SS technique, and provides shorter beam-on time rather than IMRT-SS and HT.
Interpretation of Multilocular Ameloblastoma and Root Dilation of Teeth Azda Nurma Himammi; Bambang Tri Hartomo
Radioterapi & Onkologi Indonesia Vol 12, No 2 (2021): VOLUME 12 NO.2 JULY 2021
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32532/jori.v12i2.123

Abstract

Ameloblastoma is an odontogenic tumor composed of the epithelium of the teeth, and is a benign tumor that develops slowly and does not cause pain. In general, ameloblastoma is benign and clinically ameloblastoma is usually asymptomatic and does not cause changes in sensory nerve function. The indications for periapical radiographs include, among others, to detect apical infection or an inflammation, to know the assessment of periodontal status, to know the presence of trauma to the tooth or to the alveolar bone, to assess the morphology of the tooth root before extraction, during endodontic treatment, to evaluate preoperative and postoperative apical. evaluation of apical cysts and lesions in the alveolar bone and evaluating after implant placement. The radiological features of ameloblastoma that are most often found are multilocular lesions which are often described as soap bubbles if the lesions are large and honeycomb images when the lesions are small, while unicystic ameloblastomas are seen as well-defined lesions surrounded by unerupted dental corona. This radiograph is an important diagnostic support for various types of oral lesions especially those involving the alveolar bone. The diagnosis of ameloblastoma is often made based on radiographs. In this case there was an appearance of ameloblastoma at the tip of the alveolar bone of tooth 18 which is the most common odontogenic jaw tumor, this tumor develops from epithelial tissue and dental tissue in various stages of development.
Radiation Recall Phenomenon: A Literature Review Charity Kotambunan; Soehartati A. Gondhowiardjo
Radioterapi & Onkologi Indonesia Vol 12, No 2 (2021): VOLUME 12 NO.2 JULY 2021
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32532/jori.v12i2.134

Abstract

The radiation recall phenomenon is an inflammatory reaction on a previously irradiated area of the body that occurs due to exposure to triggering agents. In cancer settings, radiotherapy is often followed by chemotherapy or other systemic therapies, and this combination can trigger the radiation recall phenomenon. The triggering agents associated with this reaction are generally cytotoxic (e.g., chemotherapy); however, other agents usage has been widely reported. This reaction manifested in various areas of the body, with the skin being the most predilection site. There is no absolute range of radiation doses associated with this reaction. The interaction among radiotherapy components, triggering agents, and time of the agent’s initiation influences the risk and onset of this phenomenon. Although known for a long time, the mechanism is ambiguous. A series of hypothetical theories are described, including their relation to stem cell function and sensitivity, vascular damage, and drug hypersensitivity reactions. Management of this reaction may include modifying triggering agents, administration of steroids, and other symptomatic therapies. In severe cases, surgical intervention can be performed. Comprehensive observational or even experimental databases are needed for this phenomenon to be entirely understood. 

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