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Holistic Nursing and Health Science
Published by Universitas Diponegoro
ISSN : -     EISSN : 26224321     DOI : -
Core Subject : Health,
Health Professions Nursing
Holistic Nursing and Health Science Journal (HNHS) (E-ISSN: 2622-4321) is an open access journal (e-journal). HNHS provides a forum for original research and scholarships relevant to nursing and other health-related professions. HNHS journal is published by Department of Master Nursing, Faculty of Medicine, Diponegoro University.
Arjuna Subject : -
Articles 112 Documents
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Durasi Pengobatan Berpengaruh terhadap Jumlah Tiap Jenis Leukosit Penderita Tuberkulosis Paru Karol Octrisdey; Made Susilawati; Fitri Rachmillah Fadmi; Winioliski L. O. Rohi Bire
Holistic Nursing and Health Science Vol 9, No 1 (2026): June (Issue in Progress)
Publisher : Master of Nursing, Faculty of Medicine, Universitas Diponegoro, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/hnhs.9.1.2026.%p

Abstract

Pulmonary tuberculosis (TB) remains one of the major public health challenges in Indonesia. The immune response to TB infection may be influenced by the treatment duration, which can be observed through changes in the composition of leukocyte types in patients undergoing therapy. However, limited studies identify the duration of TB treatment with leukocyte type count among pulmonary TB patients. This study aimed to analyze the influence of the treatment duration on leukocyte type count in pulmonary TB patients. This study implied an analytical observational design and involved 60 pulmonary TB patients selected from several health facilities. Data were collected through laboratory examinations to assess leukocyte profiles and medical record reviews to determine the treatment phase based on the duration of therapy. The data were analyzed univariately to describe the respondents’ characteristics by age and sex, and bivariate analysis used simple linear regression to assess the relationship between treatment phase and changes in leukocyte proportions. Findings showed significant effects of the treatment duration on the proportions of eosinophils (p = 0.032), lymphocytes (p = 0.005), and neutrophils (p = 0.018). Patients in a longer treatment phase exhibited an increase in lymphocyte counts, while eosinophils and neutrophils tended to decrease. These results indicate that the immune response to TB adjusts over time and that leukocyte profiles may serve as indicators of treatment effectiveness. This study provides valuable insights for healthcare professionals in understanding the immune dynamics of TB patients and optimizing therapeutic strategies to enhance treatment outcomes. AbstrakTuberkulosis paru masih menjadi tantangan besar kesehatan masyarakat di Indonesia. Respon imun terhadap infeksi tuberkulosis paru dapat mengalami perubahan sesuai dengan lama pengobatan, yang tercermin melalui perbedaan proporsi jenis leukosit pada pasien yang menjalani terapi. Penelitian yang mengindentifikasi pengaruh lama terapi tuberkulosis terhadap jumlah tiap jenis leukosit penderita tuberkulosis paru masih terbatas. Penelitian ini bertujuan untuk mengetahui pengaruh lama pengobatan terhadap tiap jenis leukosit (eosinofil, limfosit, monosit, dan neutrofil) pada pasien tuberkulosis paru. Desain penelitian ini adalah observasional analitik dengan jumlah sampel 60 pasien dari berbagai fasilitas layanan kesehatan. Data dikumpulkan melalui pemeriksaan darah dan penelaahan rekam medis untuk menentukan lama pengobatan. Analisis univariat digunakan untuk menggambarkan karakteristik responden, sedangkan uji regresi linear digunakan untuk mengevaluasi hubungan antara lama pengobatan dan komposisi jenis leukosit. Hasil menunjukkan adanya pengaruh yang signifikan antara lama pengobatan dengan jumlah eosinofil (p = 0,032), limfosit (p = 0,005), dan neutrofil (p = 0,018). Semakin lama pengobatan dijalani, terjadi peningkatan limfosit serta penurunan eosinofil dan neutrofil. Temuan ini menunjukkan adanya adaptasi imun selama terapi tuberkulosis paru dan dapat menjadi dasar dalam memantau efektivitas pengobatan.  
Diabetes Distress among Individuals Living with Diabetes in Semarang, Indonesia: A Cross-sectional Study Nadya Yumna; Niken Safitri Dyan Kusumaningrum
Holistic Nursing and Health Science Vol 9, No 1 (2026): June (Issue in Progress)
Publisher : Master of Nursing, Faculty of Medicine, Universitas Diponegoro, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/hnhs.9.1.2026.%p

Abstract

Individuals with diabetes often experience psychological challenges that may affect their health outcomes, one of which is diabetes distress. If unrecognised and unmanaged, it can impair coping abilities and self-management behaviours. This study aimed to describe the diabetes distress level among individuals with diabetes in a primary health care setting. A descriptive cross-sectional study was conducted involving individuals with diabetes residing in the working area of a public health centre in Semarang, Central Java, Indonesia. Participants were recruited consecutively, and data were collected using the Indonesian version of the Diabetes Distress Scale (DDS). Descriptive analysis was performed, and results were presented as frequencies and percentages. A total of 105 individuals participated, with a mean age of 58.5 ± 10.0 years. Overall, all participants reported slight or no diabetes distress. Specifically, none of the participants reported difficulties in physician-related distress or interpersonal distress domains. However, a small proportion experienced moderate or severe distress, particularly in the emotional burden domain (14.3%), while only 2.9% reported moderate or severe distress related to regimen adherence. Diabetes distress did not vary according to demographic or clinical characteristics. These findings indicate a generally low level of diabetes distress in this primary health care population; nevertheless, emotional burden remains a concern for some individuals. This study underscores the importance of maintaining mental health and adopting a holistic, person-centred approach to diabetes care that integrates psychosocial screening into routine primary care services. Future research with larger and more diverse samples and longitudinal designs is recommended.

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