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Jurnal Medik Veteriner
Published by Universitas Airlangga
ISSN : 26157497     EISSN : 2581012X     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Veterinary
urnal Medik Veteriner (JMV) publishes high quality and novelty papers focusing on Veterinary and Animal Science. The fields of study are anatomy, pathology, basic medicine, veterinary public health, microbiology, veterinary reproduction, parasitology, animal husbandry and animal welfare. Food animals, companion animals, equine medicine, aquatic animal, wild animals, herbal medicine, acupuncture, epidemiology, biomolecular, forensic, laboratory animals and animal models of human infections are considered. Jurnal Medik Veteriner (JMV) published two times a year: April and October.
Arjuna Subject : -
Articles 394 Documents
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Dose-dependent hepatoprotective and antioxidant effects of Cissus quadrangularis stem extract in ovariectomized rats with D-galactose-induced oxidative stress Mustafa Sabri; Teuku Reza Ferasyi; Mudhita Zikkrullah Ritonga; Muhammad Jalaluddin; Sri Wahyuni; Hamny Sofyan; Lailia Dwi Kusuma Wardhani; Denny Irmawati Hasan; Frengki Frengki
Jurnal Medik Veteriner Vol. 9 No. 2 (2026): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol9.iss2.2026.503-515

Abstract

Cissus quadrangularis is widely recognized for its antioxidant and hepatoprotective properties; however, its dose-dependent biological effects remain unclear. In this study, the dose-dependent effects of C. quadrangularis stem extract on oxidative stress, liver function, and liver histopathology were evaluated in Sprague–Dawley rats subjected to bilateral ovariectomy to induce an estrogen-deficient state, followed by D-galactose administration to induce oxidative stress. Thirty female rats were randomly divided into five groups (n = 6): a normal control group, a negative control group, and three treatment groups that received 150, 300, or 600 mg/kg body weight of the extract for 28 days, with D-galactose administered daily by intraperitoneal injection. Qualitative phytochemical screening was performed, and flavonoids, polyphenols, and triterpenoids were detected. GC–MS analysis identified steroidal compounds as the predominant chemical group (74.52%), followed by carboxylic acid derivatives (9.81%) and triterpenoids (8.49%). Serum levels of superoxide dismutase (SOD), malondialdehyde (MDA), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were measured, and liver tissues were examined histopathologically. In the group treated with 150 mg/kg body weight, ALT and AST activities were significantly altered, while liver degeneration, necrosis, and inflammatory cell infiltration were reduced compared with the negative control group. Conversely, at the higher doses (300 and 600 mg/kg body weight), decreased SOD activity, altered MDA levels, and severe liver lesions were observed. These findings indicate that C. quadrangularis exerts a dose-dependent hepatoprotective effect, with the greatest protection against oxidative liver damage observed at 150 mg/kg body weight, highlighting the importance of dose optimization for therapeutic applications.
Prevalence of Dipylidium caninum among dogs and cats in Indonesia: A meta-analysis Lintang Winantya Firdausy; Arina Mahla Sabrina; Alya Launa Afriamanda; Adib Fardanfath Arighi; Muhammad Taufiqur Rohman; Hafiz Sima
Jurnal Medik Veteriner Vol. 9 No. 2 (2026): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol9.iss2.2026.562-574

Abstract

Dipylidium caninum is a zoonotic cestode of dogs and cats whose epidemiological distribution is closely associated with flea-mediated transmission. However, evidence regarding its prevalence and epidemiological patterns in Indonesia remains geographically fragmented. This systematic review and meta-analysis aimed to estimate the pooled prevalence of D. caninum and characterize variation according to host, study period, and province. A systematic literature search was conducted using predefined PICOS criteria and reported according to PRISMA 2020. Eligible observational studies were independently screened and assessed for methodological quality using the Joanna Briggs Institute Critical Appraisal Checklist. Pooled prevalence estimates were calculated using an inverse-variance random-effects model. Subgroup analyses and meta-regression were performed to evaluate epidemiological variation, while geographical distribution was visualized using QGIS. Thirteen studies comprising 1,580 animals and 108 positive events were included. The overall pooled prevalence was 5.03% (95% CI: 2.21–11.44), with a prediction interval of 0.22–100.00%. Substantial between-study heterogeneity was observed (I² = 93.4%; τ² = 1.9102; p < 0.0001). Prevalence differed significantly by study period and province, whereas the difference between cats (6.76%) and dogs (2.82%) was not statistically significant. Meta-regression showed no significant association between study period and prevalence (β = 0.1088, p = 0.4537; R² = 0.0573). No significant funnel-plot asymmetry was detected (p = 0.6926). D. caninum is prevalent among dogs and cats in Indonesia, with substantial geographical and epidemiological variability. Standardized surveillance, diagnostic approaches, and ectoparasite-control strategies are warranted to improve epidemiological understanding and reduce transmission.
Front Cover, Editorial Board, Peer Reviewers, Acknowledgments, Table of Contents Choirun Nisa, SIIP.
Jurnal Medik Veteriner Vol. 9 No. 2 (2026): October
Publisher : Universitas Airlangga

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Abstract

Guidelines for Author, Back Cover Choirun Nisa, SIIP.
Jurnal Medik Veteriner Vol. 9 No. 2 (2026): October
Publisher : Universitas Airlangga

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Abstract

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