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Journal of Pharmaceutical and Medicinal Research Sekolah Tinggi Ilmu Farmasi Makassar Perintis Kemerdekaan Street KM 13.7 90242 Makassar-Indonesia
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Journal of Pharmaceutical and Medicinal Sciences
Published by Sekolah Tinggi Ilmu Farmasi Makassar
ISSN : 25282824     EISSN : 2580328X     DOI : -
Core Subject : Health,
Medicine & Pharmacology
The Journal of Pharmaceutical and Medicinal Sciences (JPMS) pISSN 2528-2824; eISSN 2580-328X dedicated to publish original research papers, original research notes, invited topical reviews, mini-reviews, editorial commentary and news. Medicinal resources about exchange of information and understandings about people's use of plants, fungi, animals, microorganisms, minerals, their biological and pharmacological effects based on the principles established through international conventions. Pharmaceutical including drugs, pharmacokinetics, biopharmaceutics, pharmacodynamics, pro-drug developments, metabolic disposition of bioactive agents, dosage form design, protein-peptide chemistry and biotechnology specifically as these relate to pharmaceutical technology and targeted drug delivery.
Arjuna Subject : -
Articles 4 Documents
 1 
Search results for , issue "Vol 7 No 1 (2022): JPMS Volume 7 Issue 1" : 4 Documents clear
ISOLASI DAN UJI AKTIVITAS ANTIBAKTERI ISOLAT FUNGI ENDOFIT AKAR TUMBUHAN CEMBA (Acacia rugata (Lam.) fawc. Rendle) Ismail Ismail
Jurnal Farmasi dan Ilmu Pengobatan Vol 7 No 1 (2022): JPMS Volume 7 Issue 1
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32814/jpms.v7i1.60

Abstract

Cemba (Acacia rugata (Lam.) Fawc. Rendle) is a plant endemic to South Sulawesi, especially in the Enrekang regency, has a chemical content including essential oils, flavonoids, saponins, terpenoids, steroids and alkaloids and has antibacterial properties. This study aimed to isolate endophytic fungi from the roots of the cemba plant (Acacia rugata (Lam.) Fawc. Rendle) which have the potential to produce candidate antibacterial compounds tested against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 83125. Steps in this study included the isolation of endophytic fungi. , purification, antagonist test. The results of this study allowed to obtain 3 isolates of endophytic fungi resulting from the isolation process which have different characteristics and have potential as antibacterial with strong and very strong inhibition against E.coli ATCC 83125 and S. aureus ATCC 25923.
Antibacterial Activity of Artocarpus altilis L by Thin Layer Chromatography (TLC)-Bioautography Herlina Rante; Yasnidar Yasir; Kaltum Kaltum
Jurnal Farmasi dan Ilmu Pengobatan Vol 7 No 1 (2022): JPMS Volume 7 Issue 1
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32814/jpms.v7i1.130

Abstract

This study aims to determine the antibacterial activity of breadfruit leaf extract (Artocarpus altilis L.) by TLC-Bioautography. Breadfruit leaves were extracted by maceration using ethanol as a solvent. The initial antibacterial test was carried out using the agar diffusion method using Staphylococcus aureus and Escherichia coli bacteria and then continued with the separation of compounds by TLC with n-hexane: ethyl acetate (1:1) eluent and activity test by TLC-Bioautography. The results showed that the ethanol extract of breadfruit leaves was able to inhibit E. coli and S. aureus up to a concentration of 1.25%. TLC-Bioautography test results of the ethanolic extract of breadfruit leaves (Artocarpus altilis L.) which has antibacterial activity on E. coli at an Rf value of 0.18; 0.45; 0.27 and 0.18, and S. aureus at Rf values ​​of 0.45 and 0.27.
Activity Test of Ethyl Acetate Fraction and N-Hexane Fraction of Tamarind Leaf Extract (Tamarindus indica L.) Against Healing Burns and Incision Wounds in Rabbits (Oryctolagus cuniculus) Sitti Rahimah; Suwahyuni Mus; Zulkifli Zulkifli; Nurzadrina Nurzadrina; Nurhikmah Nurhikmah; Ismail Ismail; Rahmad Aksa; Nur Rahma Rumata
Jurnal Farmasi dan Ilmu Pengobatan Vol 7 No 1 (2022): JPMS Volume 7 Issue 1
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32814/jpms.v7i1.135

Abstract

Tamarind leaf (Tamarindus indica L.) is one of the forgotten plants that has potential as a medicine for burns based on its chemical compounds such as alkaloids, flavonoids, saponins and tannins. This study aims to determine the effect of giving the ethyl acetate fraction and the n-hexane fraction of tamarind leaves on the healing of burns in rabbits (Oryctolagus cuniculus). The test was carried out using 3 rabbits for each type of treatment, namely burns and incision wounds. Each experimental animal was induced as many as 6 wounds on each back of the rabbit with the following treatments: Wound I (negative control), Wound II (bioplacenton gel), Wound III (1% n-hexane fraction), Wound IV (n-hexane fraction). 3% hexane, Wound V (1% ethyl acetate fraction) and Wound Vl (3% ethyl acetate fraction). The macroscopic observations observed included color, edema, wound diameter, scab formation and opening and epitalization. Both hexane and ethyl acetate fraction of tamarind leaf extract had activity as a burn healer at concentrations of 1% and 3%.The conclusion was that the ethyl acetate fraction of 3% tamarind leaf extract had the best activity among other treatments.
Validity and reliability test for the questionnaire: The role of the existence of pharmacists on pharmaceutical services in public perceptions Asrul Ismail
Jurnal Farmasi dan Ilmu Pengobatan Vol 7 No 1 (2022): JPMS Volume 7 Issue 1
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32814/jpms.v7i1.138

Abstract

Pharmacists have a massive role in the health care system. The pharmacist's paradigm shift, which initially focused on drugs and pharmaceutical supplies, changed to patient- and community-oriented. This change has an impact on the existence of pharmacists. Many attempts have been made to measure the extent of the pharmacist's role, one of which is by using a questionnaire. Research has been conducted on the validity and reliability of the questionnaire on public perceptions of the existence and role of pharmacists in pharmaceutical services. This study aimed to determine the validity and reliability of the pharmacist's role and existence questionnaire. This study uses the Cronbach Alpha method with the Pearson bivariate test. Questionnaires were distributed to 30 patients containing 28 questions consisting of 4 domains. There are two measurement scales: the Guttman scale and the Likert scale. The study results indicate that 28 questions have a greater significance than the r-table (0.361) on each scale. This means that the 28 questions are declared valid, while the reliability test shows an R-value of 0.588 for the Guttman scale and 0.905 for the Likert scale.

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