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Majalah Kedokteran Andalas
Published by Universitas Andalas
ISSN : 01262092     EISSN : 24425230     DOI : https://doi.org/10.25077
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Majalah Kedokteran Andalas (MKA) (p-ISSN: 0126-2092, e-ISSN: 2442-5230) is a peer-reviewed, open-access national journal published by Faculty of Medicine, Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of medicine and health, and other related disciplines
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 7 Documents
 1 
Search results for , issue "Vol 44, No 3 (2021): Online August 2021" : 7 Documents clear
KOLELITIASIS PADA ANAK Yusirwan Yusuf; Yusirwan Yusuf
Majalah Kedokteran Andalas Vol 44, No 3 (2021): Online August 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i3.p%p.2021

Abstract

Walaupun kolelitiasis merupakan kondisi yang jarang pada anak, namun penelitian terakhir menunjukkan peningkatan kasus kolelitiasis pada anak akibat dari perkembangan alat diagnostic. Penyakit ini bisa muncul dengan atau tanpa gejala, dengan tampilan anak dengan kolelitiasis simtomatik cenderung lebih jarang pada anak (17% - 50%). Lebih dari 70% batu saluran empedu pada anak-anak adalah tipe batu pigmen. Cholecystectomy sampai saat ini masih merupakan baku emas dalam penanganan kolelitiasis dengan gejala. Laparoscopic Cholecystectomy menjadi pilihan utama untuk tatalaksana kolelitiasis pada anak.Kata kunci:  kolelitiasis, laparaskopik kolesistektomi
Gambaran Bayi Berat Lahir Rendah Dengan Asfiksia di RSUP Haji Adam Malik Insana Kamilia Tampubolon
Majalah Kedokteran Andalas Vol 44, No 3 (2021): Online August 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i3.p%p.2021

Abstract

Objective: to observe the description of the condition of asphyxia in infants with low birth weight (LBW) at Haji Adam Malik General Hospital Medan. Methods: The research design is descriptive research. Data collection and collection used secondary data from medical records at the Haji Adam Malik General Hospital Medan in the period January 2016 to May 2019. The research sample was taken using a total sampling technique. Results: 33 infants with low birth weight with asphyxia were included in this study. The incidence of infants with low birth weight with asphyxia has decreased every year with the highest incidence in 2016 which was 2.98% of the total live births. The majority of babies are female (54.54%), including low birth weight (84.84%). The majority of pregnant women aged 20-35 years (87.87%) with spontaneous delivery (78.78%) and the most gestation period was below 37 weeks (84.84%). Most cases of asphyxia in infants with LBW are born to primiparous mothers. Conclusion: The picture of babies with LBW with asphyxia is generally the same as the picture in previous studies.
Pengaruh terapi dupilumab pada dermatitis atopik sedang hingga berat Elaine Purnomo; Eka Narayana Chandra; Dian Ardiana
Majalah Kedokteran Andalas Vol 44, No 3 (2021): Online August 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i3.p%p.2021

Abstract

AbstrakDupilumab merupakan antibodi monoklonal yang bekerja spesifik sebagai antagonis reseptor-α IL-4 yang menghambat kedua pensinyalan IL-4 dan IL-13 pada reseptor IL-4. Dermatitis atopik merupakan kaskade inflamasi dimediasi Th2 yang memproduksi sitokin IL-4 dan IL-13. Inflamasi kronis kulit ini disertai dengan eksaserbasi dan remisi berulang dan ditandai lesi eksem yang pruritus, yang menganggu aktivitas serta kualitas tidur pasien di malam hari dan berakibat menurunnya kualitas hidup pasien. Tujuan: Untuk mengetahui pengaruh terapi dupilumab pada dermatitis atopik sedang hingga berat; Metode: Artikel ini disusun berdasarkan review beberapa literatur yang berhubungan dengan pengaruh terapi dupilumab terhadap pengobatan dermatitis atopik sedang hingga berat; Hasil: Pada penelusuran literatur didapatkan pengaruh terapi dupilumab terhadap pengobatan dermatitis atopik sedang hingga berat berupa perbaikan indeks skor keparahan lesi serta peningkatan kualitas hidup pasien dermatitis atopik sedang hingga berat; Kesimpulan: Terdapat pengaruh terapi dupilumab terhadap perbaikan indeks skor keparahan lesi dan peningkatan kualitas hidup pasien dermatitis atopik sedang hingga berat.Kata kunci: Dupilumab; anti IL-4Rα; Dermatitis Atopik; Keparahan Lesi; Kualitas Hidup.
Gambaran Kualitas Hidup Pasien Fraktur Femur Pasca Operasi Ilham Devirxa Jusaf; Ridwan Balatif
Majalah Kedokteran Andalas Vol 44, No 3 (2021): Online August 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i3.p%p.2021

Abstract

Objective: To describe the quality of life in postoperative femoral fracture patients. Methods: This study is a descriptive study with a cross-sectional method. The sample in this study were patients diagnosed with femoral fractures and had surgery at Haji Adam Malik General Hospital Medan from the period July 2015 to December 2018. Data on patient characteristics were taken from medical records while data regarding the quality of life of patients were taken directly by researchers by interviewing patients by telephone. Quality of life was measured using the short form -36 (SF-36). Results: Most of the patients were male (81.5%), with an age range of 25-34 years being the largest age (29.6%) of femoral fracture cases in this study. The most common cause of femoral fractures was traffic accidents (85.2%). The most locations of femur fractures were in the subtrochanteric area and were not specific (25.9%). The most common type of fracture was closed fracture (66.7%). From the results of the assessment of the quality of life subvariable, almost all variables have good scores except vitality. Conclusion: Overall the patient's quality of life variable, about 59.3% of postoperative femoral fracture patients had a good quality of life.
Correlation between Oxidative Stress with Cartilage Thickness and Catalase Activity in Osteoarthritis Model Rat after MSC-WJ Treatment Endrinaldi Endrinaldi; Rauza Sukma Rita; Tofrizal Tofrizal; Sisca Dwi Yarni
Majalah Kedokteran Andalas Vol 44, No 3 (2021): Online August 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i3.p%p.2021

Abstract

Objective: This study was conducted to investigate the involvement of oxidative damage in rat model of osteoarthritis treated with Mesenchymal Stem Cell Wharton Jelly and to elucidate whether oxidative stress indicators correlate with cartilage damage and catalase activity. Methods: This research is an experimental research with Posttest-Only Control Group Design. The sample consisted of 30 OA rat divided into 5 groups. Group I was the OA rat control group, group II was the OA rat group after 4 weeks, group III was the OA rat group after 8 weeks, group IV was the OA rat group after 4 weeks of treatment with MSC-WJ and group V is the OA rat group after 8 weeks treated with MSC-WJ. Malondialdehyde were measured by Ohkawa method, Cartilage Thickness were measured by using the Betaview program and catalase activity were measured by modification of Shinha.Results: The results showed that the analysis of the Correlation between MDA with Cartilage Thickness (r= – 0.665) and CAT activity (r= – 0.666) in osteoarthritis Model Rat after Mesenchymal Stem Cell Wharton’s Jelly Treatment.Conclusion: This study demonstrated a strong negative correlation between oxidative stress and knee cartilage thickness and catalase activity of MSC-WJ treated OA rats.
Karakteristik Pasien Otitis Media Supuratif Kronik di RSUP Haji Adam Malik Medan Ayu Debora Nainggolan; Ridwan Balatif
Majalah Kedokteran Andalas Vol 44, No 3 (2021): Online August 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i3.p%p.2021

Abstract

Objective: Knowing the current picture regarding the profile of patients with chronic suppurative otitis media (CSOM) at Haji Adam Malik General Hospital Medan.  Method: This study is a descriptive study to get an overview of CSOM patients at the Haji Adam Malik General Hospital. The sampling technique in this study used total sampling. Data on CSOM patients were taken from medical records. Samples that meet the criteria for inclusion in this study are CSOM patients with complete medical records. Results: A total of 130 CSOM patient data were included in this study. The majority of CSOM patients are in the age range of 11-20 years and 21-30 years, each with 33 patients (25.4%). Most of the patients were male (63.1%) and did not work (55.4%). The main complaint of most CSOM patients in this study was otorrhoea (36.9%) and 63.8% of CSOM cases were benign. About 20.8% of CSOM patients had no complications and the most treatment for CSOM patients was collapsed wall tympanomastoidectomy (36.2%). Conclusion: The description of CSOM patients at Haji Adam Malik Hospital Medan has a similar picture with CSOM patients in general.
Peripartum Cardiomyopathy in Preterm Pregnant Women during the Covid 19 Pandemic Putri Handayani
Majalah Kedokteran Andalas Vol 44, No 3 (2021): Online August 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i3.p%p.2021

Abstract

Peripartum cardiomyopathy (PPCM) is a life-threatening disease with left ventricular (LV) dysfunction towards the end of pregnancy or in the months following delivery in women previously had no heart disease. Symptoms of heart failure (HF) are the main clinical manifestations of PPCM. Many pregnant women near the end of pregnancy experience shortness of breath, fatigue, swelling of the legs, which are symptoms identical to normal effects found in pregnancy. These symptoms are almost similar to early HF, so they often go unnoticed by medical personnel. Objective: We reported a case of PPCM that occurred during preterm pregnancy. Case: 29 years old woman, 33-34 weeks pregnant with a history of severe preeclampsia. The patient complained worsening shortness of breath for the last 5 days, but suspected that the symptom was just a normal process of growing pregnancy. In echocardiography examination found that the patient had LV dysfunction with low ejection fraction (EF) of 30%. The patient was diagnosed with PPCM in preterm pregnancy. Conclusion: Based on this case report, early identification of PPCM is a good predictor of outcome, because early treatment is given.Keywords: Peripartum cardiomyopathy; heart failure; pregnancy

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