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Dina Keumala Sari
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+6281397177693
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sumej@usu.ac.id
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Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia
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Kota medan,
Sumatera utara
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Sumatera Medical Journal
Published by Universitas Sumatera Utara
ISSN : 26229234     EISSN : 26221357     DOI : 10.32734
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology
Sumatera Medical Journal (SUMEJ) provides a forum for publishing the full research articles in the area of Medical Science related to topics from the following subject areas: -Cancer and Related Aspects -Biomoleculer in Basic Sciences -Biomoleculer in Clinical Sciences -Tissue Engineering including Stem Cell -Medical and Health Sciences
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 8 Documents
 1 
Search results for , issue "Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)" : 8 Documents clear
Skin Care in Dermatology: Between Organic Versus Synthetic Products Zulfa, Riefka Ananda; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.10427

Abstract

Background: Various skin care products have been used and played essential roles in maintaining good skin conditions. Over the last few decades, cosmetic industries and pharmacies have evolved and created skin care products according to the needs of each skin type, either based on organic or synthetic products. Objective: This article compares organic and synthetic products based on their ingredients, functions, and side effects.  Methods: This is a literature review to analyse the skin care in dermatology. Results: Natural or organic products were produced from natural ingredients, such as plants, flowers, and fruits, while synthetic products were made from a combination of organic chemical compounds. Conclusion: Both products work effectively on the skin according to their contents, but adverse effects can also occur, such as mucocutaneous reactions, edema, and allergies.
Cerebral Toxoplasmosis and Latent Tuberculosis Infection in HIV Infected Patient Arridho, Rijalun; Raveinal; Dwitya Elvira
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.11843

Abstract

Background: Toxoplasmosis is an opportunistic infection caused by Toxopasma gondii, which affects one third of the global human population and commonly involves the central nervous system (CNS)/brain. The diagnosis of obvious sign of imaging method cerebral toxoplasmosis is commonly reported in several case report, but subclinical sign of imaging is uncommon reported. Objective: we reported a case of 28-years-old male with chief complaint headache that worsening since 3 days before admission. Methods: This is a case report. Results: He was first recognized as HIV infected patient on hospital admission. CT scan revealed minimal perifocal oedema in left frontal region. Patient was diagnosed as cerebral toxoplasmosis and latent tuberculosis infection in HIV clinical stadium IV. Patient recieved empirical therapy of cerebral toxoplasmosis and symptom relieved after 7 days of treatment. Cerebral toxoplasmosisis typically associated with HIV infected patient that result in the reactivation of Toxoplasma gondii infection. Conclusions: Clinical presentation of CNS toxoplasmosis varies and normal brain CT can be found despited presumptive diagnosis was revealed.
A Study on Impact of Covid-19 on Job Performance & Job Satisfaction of Employees Engaged in WFH Culture Mahendher, Sheetal; Pattanayak, Siddharth
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.14646

Abstract

Background: Coronavirus (COVID-19), which hit in early 2020, altered people's lives and livelihoods. Objective: The goal of this study was to fill in the gaps by looking into numerous possible determinants of job satisfaction and employee performance while working from home, such as work–life balance and work stress, as well as the influence of COVID-19. Methods: This study is descriptive design, a cross sectional study, the data is collected using primary methods that is widely accepted to measure the job satisfaction and employee performance during working from home. Results: Age of respondent was100% of the respondents belong to the category of the age group 18-30. Gender of the respondents -68.2% of the respondents were male while 31.8 % of the respondents belong to the female category. Occupation of the respondents - 86.4% of the respondents were students while 13.6% belong to the employed category. As the significance value that is .072 so it depicts that Covid-19 has a statistically 0.72 impact on Employee performance. Conclusion: Working from home might be a positive indicator in reaction to the collectivist environment.
Protein Programmed Death-Ligand 1 Expression in Non-Small Cell Lung Cancer (NSCLC) and Its Correlation to Smoking Status in North Sumatera Population Soeroso, Noni Novisari; Tarigan, Setia Putra; Rahmat Hidayat; Elisna Syahruddin; Evlin Suzanna; Dian Chayadi
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.15289

Abstract

Background: Tobacco smoking is associated to the increase risk of lung cancer, and smoking could also trigger the tumour proportion score from programmed death ligand (PD-L1). Objective: This study aims to identify the correlation of non-small cell lung cancer (NSCLC) with the PD-L1 expression and smoking profile on the North Sumatra Population. Methods: This research implemented a descriptive study with cross-sectional design. Results: This study was carried out from August 2019 to September 2020. Results: Characteristics of patients with NSCLC to the PD-L1 expression were found more in male patients with percentage of 88.6%, whereas the most common type of cancer is adenocarcinoma, accounting for 97.14% of cases with mild degree smoking index for 45.7% (Brinkman index) and IV-stage of clinical status for 68.6%. The tumour proportion score with 1-49% was 51.4% with high expression of PD-L1 (positive) for 74.28%, while lower expression of PD-L1 accounted for 45%. Conclusion: There is a correlation between PD-L1 expression and smoking status in NSCLC patients, with p-value of 0.037 (<0.05).
A Natural Food Colourant from Dioscorea alata (Dandila) in Sri Lanka: Development, Storage Stability and Bio-active Properties Menike, W.A.E.M.P.; Sajiwanie, J.W.A.; Rathnayaka, R.M.U.S.K.
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.15784

Abstract

Background: Though anthocyanins are popular as natural food colourants with additional functional properties, their instability limited their utilization in the industry. Objective: this study aimed to formulate a natural food colourant by the microwave-assisted encapsulation of Dandila (Dioscorea alata) anthocyanins to enhance the storage stability of the pigments in ambient conditions and to study the storage stability and the bio-active properties of the formulated colourant. Methods: This was an in vitro study, the steps were acidified water was used as the solvent to extract the anthocyanins from Dandila yams. The colourant formulation encapsulated with maltodextrin (30 mg/ml) was selected as the best encapsulation treatment for Dandila anthocyanin. Anthocyanin degradation was not significant during the tested 12 months of storage period. Results: Noteworthy values were obtained for Total Phenolic Content and anti-oxidant activity. Among the tested strains in the antimicrobial assay, the natural colourant showed inhibitory activities against Escherichia coli and Streptococcus pneumoniae. Conclusions:  confirm the successful development of a natural colourant rich in bio-active properties from Dandila anthocyanin while ensuring its storage stability in ambient conditions.
Glucose to Complications: Understanding Secondary Effects in Diabetes Mellitus P. K. Prabhakar
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.15998

Abstract

Background: Diabetes Mellitus (DM) is a complex metabolic disorder characterized by persistent hyperglycemia, impacting millions globally. While glucose control is central to its management, understanding secondary complications is crucial for comprehensive care. Objective: This paper explores the intricate relationship "From Glucose to Complications" in DM, elucidating the pathophysiological mechanisms and organ system involvement. Methods: This paper emphasizes preventive strategies and holistic management approaches to mitigate complications. Results: Microvascular complications encompass diabetic retinopathy, nephropathy, and neuropathy, each posing significant morbidity and mortality risks. Macrovascular complications, including atherosclerosis and stroke, contribute substantially to cardiovascular morbidity in diabetic individuals. Metabolic derangements such as dyslipidemia and obesity further exacerbate the risk profile. Endocrine disturbances, neurological sequelae, and cognitive impairments represent additional burdens in DM management. Conclusion: effective management of Diabetes Mellitus (DM) and its associated complications necessitates a multifaceted approach encompassing glycemic control, lifestyle interventions, and pharmacological therapies.
Unraveling the Complexities of Polycystic Ovarian Syndrome: A Comprehensive Review Archana Kumari; Satya Narayan jha
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.16035

Abstract

Background: Polycystic Ovarian Syndrome (PCOS) is a complex endocrine disorder affecting reproductive-age women, characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology. Objective: The aimed was to explore the key topics including the role of insulin resistance and hyperinsulinemia in PCOS pathogenesis, the impact of hormonal imbalances on menstrual irregularities and fertility, and the association of PCOS with metabolic syndrome and cardiovascular risk factors. Methods: This comprehensive review delves into the multifaceted nature of PCOS, exploring its etiology, pathophysiology, clinical manifestations, diagnostic criteria, and management strategies. Results: The review discusses current diagnostic criteria and controversies surrounding PCOS diagnosis, as well as evidence-based approaches to treatment, encompassing lifestyle modifications, pharmacological interventions, and assisted reproductive technologies. Conclusion: By synthesizing current knowledge and emerging research findings, this review aims to provide a comprehensive overview of PCOS for clinicians, researchers, and individuals affected by this prevalent endocrine disorder.
Depression and Type 2 Diabetes: Dissecting the Causal Mechanisms Awani Kumar Diwakar
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.16112

Abstract

Background: Depression and Type 2 Diabetes (T2D) are two prevalent and debilitating chronic conditions that often coexist and exhibit a bidirectional relationship. Objective: This aims was to dissect the causal mechanisms underlying the association between depression and T2D, shedding light on the complex interplay between these two disorders. Methods: This was review paper that will explore about epidemiological evidence that found association between depression and an increased risk of developing T2D, as well as a reciprocal relationship where T2D serves as a risk factor for depression onset. Results: Various biological, psychological, and behavioral mechanisms have been proposed to underlie this bidirectional relationship. Depression is thought to contribute to the development of T2D through dysregulation of neuroendocrine pathways, increased inflammation, alterations in lifestyle behaviors, and poor treatment adherence. Conversely, T2D may exacerbate or precipitate depression through mechanisms involving insulin resistance, hyperglycemia-induced neuronal damage, inflammation, and the impact of chronic illness on psychological well-being. Conclusion: Understanding the causal mechanisms underlying the depression-T2D relationship is crucial for informing clinical practice, public health strategies, and the development of personalized interventions aimed at mitigating the burden of these interconnected disorders.

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