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All Journal Buletin Farmatera Sumatera Medical Journal SCRIPTA SCORE Scientific Medical Journal Cermin Dunia Kedokteran The Journal of Society Medicine (JSOCMED) Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia Cermin Dunia Kedokteran

Nelva Karmila Jusuf

Department Of Dermatovenereology, Medical Faculty University Of Sumatera Utara, RSUP H. Adam Malik Jl. Bunga Lau17 , Medan

Author-ID : 1506089

Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Identification of Candida Species on The Skin of Diabetes Mellitus Patients Al Hafiz, OK. Muhammad; Amelia, Rina; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Intertriginous candidiasis is a type of candidiasis which the lesion lies in the folds of the armpit, groin, intergluteal, folding of the breast, between the fingers or the toes, glans penis, and the umbilicus. One of the risk factors for intertriginous candidiasis is diabetes mellitus (DM). DM is a typical clinical syndrome characterized by the presence of hyperglycemia which is caused by deficiency or the decrease of insulin effectivity. Fungal infection of the skin with Candida species becomes easier in patients with immunocompromised conditions such as DM patients. Objective: To identify the Candida species in DM patient's skin. Method: This research is an observational descriptive study with cross sectional design. This research identifies Candida species from 30 DM patients at The Public Health Center Sentosa Baru Medan who met the inclusion and exclusion criteria by skin scraping with KOH 10% and slide culture. Results: The location of the rash was found in the crotch folds 63.3% and in the intergluteal 36.7%. All samples (100%) showed positive fungus structure with KOH 10% examination. On the examination of slide culture with Saboraoud Dextrose Agar media and identification of slide colony with Corn Meal Agar medium as many as 60% Candida spesies was found with overall species are Candida albicans.

Quality of Life Assessment in Skin Tag Patients Putra, Imam Budi; Jusuf, Nelva Karmila; Kartayana, Johan
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Patients with skin disease may experience clinical symptoms, such as itching, pain, and discomfort, that can have a negative impact on quality of life (QOL). Skin tag is a common benign tumor of the skin with small, soft pedunculated protrusion, it commonly occures in axilla, neck and major flexura area, despitethe lesion usually asimptomatic, sometimes patients complain about cosmetics appereances, itching or discomfort experienced. Objective: The aim of our study was to assess the impact of skin tag lesion on quality of life of patients. Method: This is a descriptive study with a cross sectional design, involving 50 patients with skin tag lesion who visited the Dermatology outpatient clinic Adam Malik General Hospital, Medan from September 2016 to October 2016. The patients were filled Indonesian version of skindex-29 questionnaire to measures the effects of skin disorders on their QOL. Result: In this study QOL in skin tag patient was fairly good, 38(76%) subjects had a skindex-29 category score<5, and 12(24%) subjects had a skindex-29 score 6-17. We didn’t findimpaired QOL in all skin tag patients. Conclusion: In this study’s we concluded skin tag does not affect the quality of life of the patients.

Quality of Life in Vitiligo Patients at H. Adam Malik General Hospital Medan, Indonesia Jusuf, Nelva Karmila; Putra, Imam Budi; Utami, Dina Rizki
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Abstract. Background: Vitiligo is an acquired depigmenting skin disorder that can affect the patients’ quality of life (QOL). Objectives: The aim of this study was to evaluate the QOL in patients with vitiligo. Methods: This study included 30 patients with vitiligo. All the patients filled out questionnaires Skindex- 29. Data were compiled and analyzed statistically. Results: Among the 30 vitiligo patients, 73,3 % were women and 26,7 % were men. Mean age of patients were 40.53 ± 12. 91 years old. The mean duration of vitiligo was 9.07 ± 7.643 years. The mean total Skindex-29 score of the subjects was 24.68 ± 7,72. There was significant difference according to age’s group (p = 0,035) and sex (p = 0,01) but there is no significant difference according to duration of disease’s group (p = 0,582). Conclusions: The study findings showed that vitiligo has a significant effect on the patients’ QOL. It seems counselling is needed as part of treatment in vitiligo patients.

In Vitro Antimicrobial Activity of Bawang Batak Bulbs (Allium Chinense G. Don) Against Methicillin-Resistant Staphylococcus Aureus Aretha, Tiasarah; Jusuf , Nelva Karmila
Sumatera Medical Journal Vol. 2 No. 2 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Introduction: Staphylococcus aureus infection can cause pyoderma. These days there is a shift in Staphylococcus aureus sensitivity to antibiotics that is marked by the existence of Methicillin-Resistant Staphyloccus aureus, so alternative therapy that is herbal medicine might be needed. There are a lot of medicinal plants in Indonesia, but until today the usage is still minimum. One of the plant genus that is already being used is allium that had been known to have antimicrobial activity. The genus allium that is consumed a lot by Indonesians especially people of North Sumatra is bawang batak (Allium chinense G.Don.). This study is conducted to assess the antimicrobial activity of bawang batak bulbs in several concentrations to MRSA. Methods: This research is an experimental research with agar diffusion method. The extracts were divided into six groups: extracts in concentration level of 6.25%, 12.5%, 25%, 50%, 100% and a negative control (DMSO). The sample size is four per group with total sample of 24. Results: The results showed that the inhibition of bacterial growth occured at the concentration levels of 50% and 100% with inhibition zone diameters of 8.695 mm and 10.545 mm respectively. Extracts with concentration levels of 25%, 12.5% and 6.25% did not show any inhibition. Conclusion: Bawang batak bulbs extract can be used to inhibit the growth of MRSA

IDENTIFICATION OF CANDIDA SPECIES ON THE SKIN OF DIABETES MELLITUS PATIENTS Al Hafiz, OK Muhammad; Amelia, Rina; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.76

Background: Intertriginous candidiasis is a type of candidiasis which the lesion lies in the folds of the armpit, groin, intergluteal, folding of the breast, between the fingers or the toes, glans penis, and the umbilicus. One of the risk factors for intertriginous candidiasis is diabetes mellitus (DM). DM is a typical clinical syndrome characterized by the presence of hyperglycemia which is caused by deficiency or the decrease of insulin effectivity. Fungal infection of the skin with Candida species becomes easier in patients with immunocompromised conditions such as DM patients.Objective: To identify the Candida species in DM patient's skin.Method: This research is an observational descriptive study with cross sectional design. This research identifies Candida species from 30 DM patients at The Public Health Center Sentosa BaruMedan who met the inclusion and exclusion criteria by skin scraping with KOH 10% and slide culture.RESULTS: The location of the rash was found in the crotch folds 63.3% and in the intergluteal 36.7%. All samples (100%) showed positive fungus structure with KOH 10% examination. On theexamination of slide culture with Saboraoud Dextrose Agar media and identification of slide colony with Corn Meal Agar medium as many as 60% Candida spesies was found with overallspecies are Candida albicans.Conclusions: The identification of Candida Species on the skin of DM patients showed as many as 60% Candida albicans was found

QUALITY OF LIFE IN VITILIGO PATIENTS AT H. ADAM MALIK GENERAL HOSPITAL MEDAN, INDONESIA Jusuf, Nelva Karmila; putra, imam budi; utami, dina rizki
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.79

Background: Vitiligo is an acquired depigmenting skin disorder that can affect the patients’ quality of life (QOL).Objectives: The aim of this study was to evaluate the QOL in patients with vitiligo.Patients and Methods: This study included 30 patients with vitiligo. All the patients filled out questionnaires Skindex- 29. Data were compiled and analyzed statistically.Results: Among the 30 vitiligo patients, 73,3 % were women and 26,7 % were men. Mean age of patients were 40.53 ± 12. 91 years old. The mean duration of vitiligo was 9.07 ± 7.643 years. Themean total Skindex-29 score of the subjects was 24.68 ± 7,72. There was significant difference according to age’s group (p =0,035) and sex ( p = 0,01) but there is no significant difference according to duration of disease’s group ( p = 0,582 ).Conclusions: The study findings showed that vitiligo has a significant effect on the patients’ QOL. It seems counselling is needed as part of treatment in vitiligo patients.

QUALITY OF LIFE ASSESSMENT IN SKIN TAG PATIENTS putra, imam budi; Jusuf, Nelva Karmila; Kartayana, Johan
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.80

Background: Patients with skin disease may experience clinical symptoms, such as itching, pain, and discomfort, that can have a negative impact on quality of life (QOL).Skin tag is a common benign tumor of the skin with small, soft pedunculated protrusion, it commonly occur in axilla, neck and major flexura area, despitethe lesion usually asimptomatic, sometimes patients complainabout cosmetics appereance, itching or discomfort experienced.Objective : The aim of our study was to assess the impact of skin tag lesion on quality of life of patients.Material and Method: This is a descriptive study with a cross sectional design, involving 50 patients with skin tag lesion who visited the Dermatology outpatient clinic Adam Malik GeneralHospital, Medan from September 2016 to October 2016. Thepatients were filled Indonesian version of skindex-29 questionnaire to measures the effects of skin disorders on their QOL.Results: In this study QOL in skin tag patient was fairly good, 38(76%) subjects had a skindex-29 category score<5, and 12(24%) subjects had a skindex-29 score 6-17. We didn’t findimpaired QOL in all skin tag patients.Conclusion : In this study we concludedskin tag does not affect the quality of life of the patients.

Combination Therapy in Melasma with Lentigo Solaris: Case Report Lumbantoruan, Erty Witalaya; Nasution, Khairina; Nelva Karmila Jusuf
Sumatera Medical Journal Vol. 3 No. 1 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i1.690

Background: Melasma and lentigo solaris are common, recurrent, and refractory acquired hyperpigmentation disorder. In spite of variety of therapeutic options available for this cosmetically disfiguring condition, the treatment of this condition remains a challenge. Azelaic acid (AA) is a depigmenting agent which acts by inhibition of DNA synthesis and mitochondrial enzymes, thereby inducing direct cytotoxic effects on melanocytes. Glycolic acid (GA) peel is one of the most versatile agents in the treatment of melasma and lentigo solaris. GA peels alone or in combination with topical hypopigmenting agents has shown encouraging results. However, there is paucity of controlled trial demonstrating the efficacy of GA peels in conjunction with topical AA. Case: A 42-years-old female, works as a street vendor, came with dark brown spots on both cheeks, nose, chin and forehead that spreads to whole face since one year ago. She had a history of using contraceptives. From the dermatological examination, there were multiple well-circumscribed, irregular hyperpigmented macules that asymmetrical, with size ranging from lenticular to plaque on the maxillary, left buccalis, mentalis and frontalis region. We also found a numular dark brown hyperpigmented macules on right zygoma. She was diagnosed with melasma and lentigo solaris. The Melasma Area Severity Index (MASI) score was 25.6, which classified as moderate melasma. She was treated with 20% azaleic acid cream twice a day, broadspectrum sunscreen with SPF 50 and GA 20% peeling. Result: After 6 weeks of treatment, there were significant improvement in both melasma and lentigo solaris.

The Association Between Skin Types and Acne Vulgaris Tamba, Asnita Bella Putri; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 3 No. 1 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i1.3279

The skin problem often found on adolescents is acne vulgaris. The pathogenesis of acne vulgaris is multifactorial, from increased production of sebum, hyperproliferation of pilosebaceous follicles, colonization of Cutibacterium acnes, to inflammation process. The elevated sebum production which is often linked to oily skin type could result in acne vulgaris in adolescents. According to Baumann Skin Type, one of the parameters in categorizing skin type is having either oily or dry skin. Acne vulgaris is also found on dry skin. This research aims to find the association between skin types and acne vulgaris. It is an analitic research with cross-sectional method. The data were acquired from 93 students of SMA Santo Thomas 1 Medan who fulfilled the inclusion criteria with stratified random sampling method. The collection of data were primarily carried out with dermatology examination and Baumann Skin Type questionnaire to determine the skin types. Then, they were analyzed with Chi-square test to see the relationship between skin types and acne vulgaris. The obtained results show that 73 (78,5%) out of 93 students suffered from acne vulgaris with predominance being female (39,8%) than male (38,7%), and those in 15-year age group (38,7%). The most commonly observed skin type on samples is oily skin (79,6%). The bivariate analysis with acquired p-value of 0,002 (p<0,05) led to a conclusion that there is a significant association between skin types and acne vulgaris.

Risk Factors Analysis of Premature Canities in Medical Students of Universitas Sumatera Utara Class 2016-2018 Eka Zhaki Safira Lubis; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 3 No. 1 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i1.3543

Abstract. Background. Premature canities is a terminology to describe a premature graying of hair before the age of 25 in Asians.The ethiopathogenesis of premature canities is still not fully understood, but there are risk factors associated to premature canities such as gender, family history, obesity, smoking, alcohol consumption, other disease, micronutrients deficiencies. Aims: to evaluate risk factors that influence the incidence of premature canities in medical students of University of Sumatera Utara class 2016-2018. Methods: This research is an analytic research with the number of subjects are 80 respondents using bivariate and multivariate analysis using logistic regression test. Results: of the 80 respondents, 57 respondents (71,2%) had premature canities. Based on bivariate analysis, it was obtained p value ≤ 0,05 for family history and stress, Based on multiavariate analysis, it was obtained p value ≤ 0,05 for family history (p value = 0,000), which means family history is the most dominants factors for premature canities. Conclusion: there is a correlation between premature canities and family history and stress and Family history is the most dominant risk factors that associated to premature canities in medical students of University of Sumatera Utara class 2016-2018.

Co-Authors Al Hafiz, OK Muhammad Al Hafiz, OK. Muhammad Amalia, Rina Amelia, Rina Annisa Astari Aretha, Tiasarah Danil, Rezkyana Deliana, Rizka Dhillon, Jesryn Eka Zhaki Safira Lubis Fitri Puspita Ira Armayanti Kartayana, Johan Kartayana, Johan Khairina, Fadilah Oliv Lubis, Ade Fitriyani Lubis, Nabila Adani Lubis, Sri Nauli Dewi Lumbantoruan, Erty Witalaya Malinda, Ifen Ayu Meutia, Nanda Mutia Fadhila Sy Nasution, Khairina Oentari, Widyaningsih Putra, Imam Budi Rina Amelia Risanti, Rinda Chindra Rosyada, Rahma Rudi Chandra Sari, Lovena Setio Wati, Sri Karunia Siahaan, Ade Gustina Simanjuntak, Desy Sahara Putri Sutrisno, Angie Regina Tamba, Asnita Bella Putri Tasmil, Adina Miltania Tengku, Nabila Nurhafizha utami, dina rizki Utami, Dina Rizki Wiryadana, Michelle Wulandari, Puteri Yosi, Ariyati

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