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Sumatera Medical Journal

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Published by Universitas Sumatera Utara

ISSN : 26229234 EISSN : 26221357 DOI : 10.32734

Core Subject : Health, Science,

Immunology & microbiology Medicine & Pharmacology

Sumatera Medical Journal (SUMEJ) provides a forum for publishing the full research articles in the area of Medical Science related to topics from the following subject areas: -Cancer and Related Aspects -Biomoleculer in Basic Sciences -Biomoleculer in Clinical Sciences -Tissue Engineering including Stem Cell -Medical and Health Sciences

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 162 Documents

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Comparison Pai-1 Level in Type 2 Diabetes Mellitus with and Without Diabetic Foot Ulcer Sholat, Alfi Dewi; Gatot, Dairion; Handayani, Savina; Mardia, Andri Iskandar; Syafril, Santi
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

In type 2 diabetes mellitus, there are changes in hemostasis components, including overexpression of PAI-1. By these facts, the authors are interested in conducting the study of PAI-1 level in diabetic patients with and without foot ulcer. Methods: The sample of this research was collected cross-sectionally on 20 type 2 diabetic patients with foot ulcer and 20 without foot ulcer. Blood samples were taken to measure serum PAI-1 level, complete blood count and hemostasis screening test. Results: Statistical analysis showed there are significant differences in hemoglobin, trombosit, Fibrinogen and D-dimer levels in the ulcer and non-ulcer groups but no significant difference in PAI-1 level. Conclusions: No higher PAI – 1 level were found in diabetic foot ulcer group than those without diabetic foot ulcer. There was no significant difference between PAI-1 level and grade of diabetic foot ulcer.

Correlation between Breastfeeding Duration and Motor Development in Children Siregar, Gurnal Rai Gandra; Lubis, Munar; Fujiati, Isti Ilmiati
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

World Health Organization (WHO) recommends to continue breastfeeding until two years of age. There are few studies assessing the correlation between breastfeeding duration and motor development. A cross-sectional study was conducted in April 2016 in Muara Batang Gadis District. The sample were children 3-6 years of age. Breastfeeding duration was obtained by interview, and motor development was assessed using Denver Developmental Screening Test II. Chi-square test was used to evaluate the correlation between breastfeeding duration and motor development, with P-value <0.05 and 95% Confidence Interval (CI). Among 204 children, 5.4% had the fine motor delay, and 1% had the gross motor delay. Children with breastfeeding duration for at least for two years had better fine motor development compared to breastfeeding duration for less than two years (P<0.001, PR=1.139, 95% CI=1.055-1.231) and there is no difference in gross motor development (P=0.193, PR=1.023, 95% CI=0.991-1.055). There is a correlation between breastfeeding duration and fine motor development.

Identification of Candida Species on The Skin of Diabetes Mellitus Patients Al Hafiz, OK. Muhammad; Amelia, Rina; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Intertriginous candidiasis is a type of candidiasis which the lesion lies in the folds of the armpit, groin, intergluteal, folding of the breast, between the fingers or the toes, glans penis, and the umbilicus. One of the risk factors for intertriginous candidiasis is diabetes mellitus (DM). DM is a typical clinical syndrome characterized by the presence of hyperglycemia which is caused by deficiency or the decrease of insulin effectivity. Fungal infection of the skin with Candida species becomes easier in patients with immunocompromised conditions such as DM patients. Objective: To identify the Candida species in DM patient's skin. Method: This research is an observational descriptive study with cross sectional design. This research identifies Candida species from 30 DM patients at The Public Health Center Sentosa Baru Medan who met the inclusion and exclusion criteria by skin scraping with KOH 10% and slide culture. Results: The location of the rash was found in the crotch folds 63.3% and in the intergluteal 36.7%. All samples (100%) showed positive fungus structure with KOH 10% examination. On the examination of slide culture with Saboraoud Dextrose Agar media and identification of slide colony with Corn Meal Agar medium as many as 60% Candida spesies was found with overall species are Candida albicans.

Correlation of Depression Symptoms and Interleukin-6 in Chronic Renal Disease with Regular Hemodialysis Patients Damayanti, Indah; Nasution, Habibah Hanum; Lubis, Wika Hanida
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Depression is psychosomatic disorder are common in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD). Correlated with morbidity and mortality associated with chronic inflammation in patients, that characterized by elevated levels of plasma cytokines, especially interleukin (IL)-6. Objective: To investigate the correlation of depressive symptoms with IL-6 levels in patients with CKD who underwent regular HD. Methods: One hundred and 29 CKD patients were enrolled in this cross- sectional study. All eligible patients were screened for IL-6 level. Beck Depression Inventory (BDI) II questioner were then given to determine the presence of depression. Level of IL-6 was then correlated with BDI score using Spearman test. Result: The mean BDI score was 19,32 ± 6,18 indicating the level of mild depression symptoms, and the mean IL-6 level (8,697 ± 6,947 pg/mL) was still within normal range. There was a moderate positive correlation (r = 0.417) between the level of depressive symptoms and IL- 6 levels. Conclusion: There was a moderate positive correlation (r = 0.417) between IL-6 levels and depressive symptoms in patient with HD. However, mean IL-6 levels in depressive patients are still within normal limits indicating that the cause of depression is multifactorial.

Quality of Life Assessment in Skin Tag Patients Putra, Imam Budi; Jusuf, Nelva Karmila; Kartayana, Johan
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Patients with skin disease may experience clinical symptoms, such as itching, pain, and discomfort, that can have a negative impact on quality of life (QOL). Skin tag is a common benign tumor of the skin with small, soft pedunculated protrusion, it commonly occures in axilla, neck and major flexura area, despitethe lesion usually asimptomatic, sometimes patients complain about cosmetics appereances, itching or discomfort experienced. Objective: The aim of our study was to assess the impact of skin tag lesion on quality of life of patients. Method: This is a descriptive study with a cross sectional design, involving 50 patients with skin tag lesion who visited the Dermatology outpatient clinic Adam Malik General Hospital, Medan from September 2016 to October 2016. The patients were filled Indonesian version of skindex-29 questionnaire to measures the effects of skin disorders on their QOL. Result: In this study QOL in skin tag patient was fairly good, 38(76%) subjects had a skindex-29 category score<5, and 12(24%) subjects had a skindex-29 score 6-17. We didn’t findimpaired QOL in all skin tag patients. Conclusion: In this study’s we concluded skin tag does not affect the quality of life of the patients.

Quality of Life in Vitiligo Patients at H. Adam Malik General Hospital Medan, Indonesia Jusuf, Nelva Karmila; Putra, Imam Budi; Utami, Dina Rizki
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Abstract. Background: Vitiligo is an acquired depigmenting skin disorder that can affect the patients’ quality of life (QOL). Objectives: The aim of this study was to evaluate the QOL in patients with vitiligo. Methods: This study included 30 patients with vitiligo. All the patients filled out questionnaires Skindex- 29. Data were compiled and analyzed statistically. Results: Among the 30 vitiligo patients, 73,3 % were women and 26,7 % were men. Mean age of patients were 40.53 ± 12. 91 years old. The mean duration of vitiligo was 9.07 ± 7.643 years. The mean total Skindex-29 score of the subjects was 24.68 ± 7,72. There was significant difference according to age’s group (p = 0,035) and sex (p = 0,01) but there is no significant difference according to duration of disease’s group (p = 0,582). Conclusions: The study findings showed that vitiligo has a significant effect on the patients’ QOL. It seems counselling is needed as part of treatment in vitiligo patients.

The Difference of Olfactory Functions in The Workers of The Gas Station by Using Sniffin’ Stickstest in Medan City Sagala, Irwan Pernandi; Munir, Delfitri; Rambe, Andriana Yunita Murni; Ashar, Taufik
Sumatera Medical Journal Vol. 1 No. 1 (2018): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Introduction: Chronic exposure of volatile substances can cause the impaired olfactory function. Objectives: In order to identify the difference of olfactory function in the workers of the Gas Station in Medan city. Methods: Analytical research with cross- sectional approach. The research subjects were 80 persons consisting of 40 gas station operators and 40 non-operators who fulfilled the inclusion and exclusion criteria. The applied statistical analysis was Mann Whitney, Fisher's Exact, Chi Square, T independent, Spearman with 95% confidence level. Results: Proportion of the impaired olfactory function in the gas station operator group by 77.5% and non-operator group by 0%. Significant correlation was obtained between age, duration of work with the impaired olfactory function (p = 0,047, p = 0,001). The gas station operators will suffer the impaired olfactory function if they work for  3.89 years. Conclusions: There were differences of olfactory functions in the gas station workers by using Sniffin 'Sticks Test in Medan city.

Difference in Total Serum Immunoglobulin E Level Among Patients With and Without Intravenous Contrast Media Adverse Reaction on Computed Tomography Scan Examination Ikhmawati, Yulikha; Zubir, Zuhrial; Daulay, Elvita Rahmi
Sumatera Medical Journal Vol. 2 No. 1 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

The adverse reaction (AR) to intravenous contrast media (ICM) are relatively common. Various opinions pro-posed in the mechanism of the incidence of ICM AR. Suspected that the role of Immunoglobulin E (IgE) me-diates allergic conditions that are part of the AR. Objective:To determine the difference in total serum IgE level among subjects with and without ICM AR on computed tomography (CT) scan examination. To ob-serve difference in total serum IgE levels in subjects undergoing ICM adverse reaction based on the degree of severity. Method: An analytical study with cross-sectional design of 104 subjects undergoing CT scans with ICM, examined IgE levels before and after ICM was administered, then measured the severity of adverse re-actions of contrast media. Result: In this study, subjects undergoing adverse reactions, prior to administration Iopamidol had a higher mean IgE 1270.79 mg / dl compared with those who having AR 1174.90 mg / dl and after administration of Iopamidol a mean of Ig E is still higher in subjects having AR 1507.96 mg/dl com-pared with those having negative AR that is 1325.88 mg/dl, p = 0.696, statistically, not significant. Mild reac-tions in 40 subjects (38.5%) with cough, nausea, dizziness, itching, and sweating. Conclusion: Increase in total IgE levels in subjects with positive adverse reactions are independent(p=0.696).

The Comparison of Er α Expression Between Endometriosis with No Endometriosis Syafardi, D. Irsat; Siregar, Hendry Salim; Kaban, Yostoto B; Ardiansyah, Edy
Sumatera Medical Journal Vol. 2 No. 1 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Estrogen receptors (ER) play an important role in mediating action. The ER α has a higher affinity for estrogen and the dominant form of the normal endometrium. A cross-sectional study from an ectopic tissue of endo-metriosis and normal was examined for immunohistochemistry. This research was conducted from November 2015 until the sample complete. The analysis was performed using Fisher Exact test, p <0.05 was considered to any difference of estrogen alpha receptor expression between endometriosis patients with no endometriosis. REα is more dominant in normal endometrium, whereas in the case of endometriosis in the presence of many negative expression of REα then the assumption that REβ is a receptor that many encountered. There is a dif-ference in the expression of REα between endometriosis with no endometriosis.

Relationship of Advanced Paternal Age and Onset of Schizophrenia Widyastuty, Arsusy; Gultom, Dapot P; Husada, Muhammad Surya
Sumatera Medical Journal Vol. 2 No. 1 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Background: Increased paternal age has been associated with an increased risk of spontaneous abortion, premature birth, infant mortality, congenital malformations, childhood cancer, epilepsy, autism, bipolar and schizophrenia in offspring. The biological mechanisms behind this relationship are not known but may be associated with de novo mutations and epigenetic changes in male cells with short and long term health consequences for their offspring. Males are responsible for most of the new mutations in the gene group, to the permanent distribution of reproductive cells and the number of mutations increases significantly with age. Objective: The aim of the study to determine the correlation between paternal age and onset of schizophrenia. Method: This study was correlation analysis with cross sectional approach with The subject is 92 schizophrenia patient. Analysis of the data using statistical test that is chi-square. Result: the study findings showed there was significant correlation between paternal age with schizophrenic aged onset of 0.001 (p <0.05).

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Dina Keumala Sari

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+6281397177693

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sumej@usu.ac.id

Editorial Address
Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia

Location
Kota medan,

Sumatera utara

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Dina Keumala Sari

Contact Email dina@usu.ac.id

Phone +6281397177693

Journal Mail Official sumej@usu.ac.id

Editorial Address Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia

Location Kota medan, Sumatera utara INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Dina Keumala Sari

Contact Email
dina@usu.ac.id

Phone
+6281397177693

Journal Mail Official
sumej@usu.ac.id

Editorial Address
Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia

Location
Kota medan,

Sumatera utara

INDONESIA