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Contact Name
Dr. dr. Puspa Wardhani, SpPK
Contact Email
admin@indonesianjournalofclinicalpathology.org
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+6285733220600
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majalah.jicp@yahoo.com
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Laboratorium Patologi Klinik RSUD Dr. Soetomo Jl. Mayjend. Prof. Dr. Moestopo 6-8 Surabaya
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Kota adm. jakarta selatan,
Dki jakarta
INDONESIA
Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
ISSN : 08544263     EISSN : 24774685     DOI : https://dx.doi.org/10.24293
Core Subject : Health, Science,
Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) is a journal published by “Association of Clinical Pathologist” professional association. This journal displays articles in the Clinical Pathology and Medical Laboratory scope. Clinical Pathology has a couple of subdivisions, namely: Clinical Chemistry, Hematology, Immunology and Serology, Microbiology and Infectious Disease, Hepatology, Cardiovascular, Endocrinology, Blood Transfusion, Nephrology, and Molecular Biology. Scientific articles of these topics, mainly emphasize on the laboratory examinations, pathophysiology, and pathogenesis in a disease.
Articles 24 Documents
Search results for , issue "Vol 24, No 3 (2018)" : 24 Documents clear
GALECTIN-3, MMP-9 AND ST-2: BIOCHEMICAL MARKERS IN CARDIOVASCULAR DISEASES Anak Agung Wiradewi Lestari
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 24, No 3 (2018)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v24i3.1421

Abstract

Galectin-3 is a reasonably stable biomarker. It can be detected even before the onset of heart failure occurs. Heart Failure (HF) is one of the complications of AMI as well as one of the major cardiovascular parameters. One study showed that elevated levels of Galectin-3 that persisted up to 3-6 months of the follow-up period in patients with heart failure were associated with a poorer prognosis. Many studies explain that the role of Galectin-3 is strong in cardiac remodeling/fibrosis and the occurrence of heart failure. Inhibition of Galectin-3 by pharmacological agents has been shown to be able to the prevent that cardiac fibrosis process, particularly in patients with advanced heart failure. Since its discovery as a gene product induced by cardiomyocyte stretch in vitro, ST2 has emerged as a powerful player with IL-33 in modulating ventricular function and remodeling via effects on apoptosis, inflammation and myocardial fibrosis. Clinically, measurement of sST2 appears promising as a biomarker for remodeling and outcome across the AHA HF Stages. Circulating levels of sST2 are strongly related to short and long-term post-discharge mortality in acute coronary syndromes and HF, as well as markers of cardiac structure and function. Current pre-clinical and clinical documentation strongly support MMP-9 as a panel member in the biomarker list to diagnose or treat the pathophysiology of post-MI ventricular remodeling and congestive heart failure. Based on the evidence provided, further prospective studies are required to assess the prognostic value of MMP-9 for post-MI remodeling, particularly in comparison with traditional markers.  
THE CORRELATION OF OBESITY INDEX AND THE LEVEL OF TRIGLYCERIDE IN VILLAGERS Fenty Fenty; Lucia Wiwid Wijayanti; Aris Widayati
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 24, No 3 (2018)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v24i3.1337

Abstract

The obesity index is a parameter that describes general and central obesity. Obesity prevalence tends to increase in the rural areas of Indonesia. The increased prevalence of obesity is correlated with increased cardiovascular prevalence and diabetes. Dyslipidemia is also a risk factor for cardiovascular disease and is closely related to obesity. Obesity is an accumulation of excessive triglyceride levels and stored in adipose tissue that can contribute to the onset of coronary heart disease. This was an analytical observational study with a cross-sectional design. Research subjects were the rural community in Bonjoroyo village, Kulonprogo Regency, DIY which fulfilled the inclusion criteria. The data obtained were obesity index data (Body Mass Index/BMI, Waist Circle/LP, Waist Round/RLPP Ratio, Body Waist Ratio/RLPTB) and triglyceride levels which were then analyzed statistically with normality test and continued with correlation Spearman test with a 95% confidence level. The results showed that BMI, LP, and RLPTB measurements were significantly positively correlated with moderate-to-weak correlation strength in fasting blood triglyceride levels (r:0.435; p:0.000; r:0.362; p:0.002; r:0.347; p:0.004) in males. Measurements of BMI, LP, and RLPTB were positively correlated with a weak correlation strength against fasting blood triglyceride levels (r: 0.193; p: 0.028; r: 0.226; p: 0.010; r: 0.214; p: 0.014) in females. The RLPP obesity index did not show significant correlations to fasting triglyceride levels in rural communities.
Subjects and Authors Index Dian Wahyu Utami
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 24, No 3 (2018)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v24i3.1791

Abstract

Author Guideline and Subcribes Form Utami, Dian Wahyu
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 24, No 3 (2018)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v24i3.1792

Abstract

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