cover
Contact Name
Adinda Putra Pradhana
Contact Email
-
Phone
+628113601619
Journal Mail Official
nsmconline@gmail.com
Editorial Address
Jl. P.B. Sudirman, Dangin Puri Klod, Kec. Denpasar Bar., Kota Denpasar, Bali
Location
Kota denpasar,
Bali
INDONESIA
Neurologico Spinale Medico Chirurgico
Published by Universitas Udayana
ISSN : -     EISSN : 26212064     DOI : https://doi.org/10.36444/nsmc
Core Subject : Health, Science,
Neurologico Spinale Medico Chirurgico (NSMC) is an open-access, single-blind peer-reviewed journal, published by Indonesian Neurospine Society (INSS) under the flag of Indonesian Neurosurgery Society (INS) and Faculty of Medicine, Udayana University. NSMC publishes articles which encompass all aspects of basic research/clinical studies. The journal facilitates, bridge and integrate the intellectual, methodological, and substantive diversity of medical knowledge, especially in the field of surgery, neurology, neurosurgery, spine, neuroanesthesia, medicine, and health. The journal appreciates any contributions which promote the exchange of ideas between practising educators and medical researchers all over the world.
Articles 134 Documents
Optimizing microsurgery training for plastic surgery resident: A systematic review Gede Wara Samsarga; Agus Roy Rusly Hariantana Hamid; I Gusti Putu Hendra Sanjaya; I Gusti Ayu Putri Purwanthi; Ni Made Ratih Purnama Dewi
Neurologico Spinale Medico Chirurgico Vol 5 No 1 (2022)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36444/nsmc.v5i1.196

Abstract

Background: Microsurgery for plastic surgery residents is complex and requires a long learning curve, psychomotor capabilities, and repeated practices. Microsurgery training for plastic surgical residents must be optimized due to the heavy workload during residency and the limited time available to master microsurgery skills. Methods: Electronic literature searching of the MEDLINE (PubMed), Cochrane, and Google Scholar databases was conducted. Studies that were eligible and published between January 2015 and September 2019 were chosen. Results: Surgical simulation platforms have been implemented as a result of new training methods to learn microsurgery. Plastic surgery residents can practice microsurgery in virtual, animal models, non-living models, and indirect patient practice. Resident’s competency scores and surgical performance improve as a result of simulation-based training. The demand for simulation-based training in plastic surgery residency programs is expected to rise as a result of its usefulness. A microsurgical skill evaluation is also a mandatory aspect of enhancing microsurgical skills for plastic surgery residents. Conclusion: Because there is limited time for formal microsurgery training in the operating room, plastic surgery residents must optimize their microsurgery skills outside of the operating room. Implementation of living and non-living models for microsurgery training and standardized objective assessment tools will further advance microsurgical skills in plastic surgery resident.
Role of Rho-kinase Inhibitor and hrsACE2 in COVID-19 Patients Management Wilson Halim; Bryan Gervais de Liyis; Cokorda Istri Intan Dalem Sukawati
Neurologico Spinale Medico Chirurgico Vol 5 No 1 (2022)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36444/nsmc.v5i1.201

Abstract

The Renin-angiotensin system (RAS) plays an important role in the SARS-CoV-2 infection through Angiotensin-converting enzyme 2 (ACE2). Human recombinant soluble ACE2 (hrsACE2) has been shown to act as a competitive interceptor for SARS-CoV-2 by preventing the binding of viral particles to the ACE2. In addition, Rho-kinase inhibitors have been proven to suppress SARS-CoV-2 infection through inhibition of the Rho-associated protein kinase (ROCK) pathway. The combined effect of hrsACE2 and Rho-kinase inhibitor increases the activity and levels of ACE2 in protection through the Ang1-7 MasR, Ang1-9, and other mechanisms of protection. This literature review is done by searching journals with “COVID-19”, “ACE2”, “hrsACE2”, “Rho- kinase inhibitor”, and “ROCK pathway” as well as Boolean logic “AND” and “OR”. Relevant journals are used as references to compile systematic writing. Based on research results, hrsACE2 and Rho-kinase inhibitors have been clinically proven to protect tissue through the elevated level of ACE2 by the mechanism of Rho-kinase inhibitor, which increased Ang1-7 MasR concentration that gives vasodilatation, anti-proliferative, anti-inflammation, and anti-fibrotic effect. Rho-kinase inhibitors significantly reduce the number of infected cells by SARS-CoV-2 in COVID-19 patients. The potential of the combination therapy of Rho-kinase inhibitor and hrsACE2 therapy can be an efficient therapeutic solution for COVID-19 patients so that further research can be carried out in the future.
Comparison of Alvarado scores, Tzanakis scores, and RIPASA scores in the diagnosis of acute appendicitis in Sanglah Hospital I Made Maha Satya Dwi Palguna; Made Agus Dwianthara Sueta; Tjokorda Gde Bagus Mahadewa
Neurologico Spinale Medico Chirurgico Vol 5 No 1 (2022)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36444/nsmc.v5i1.204

Abstract

Background: Acute appendicitis (AA) is the most common cause of gastrointestinal emergency surgery worldwide. However, to confirm the diagnosis of acute appendicitis, it is largely dependent on clinical judgment, causing the rate of negative appendectomy or misdiagnosis reach 20 – 40%. Several scoring systems have been developed to identify patients who did not require surgery, thereby reducing the burden of negative appendectomy. Methods This study is a cross-sectional observational study with diagnostic tests. The study was conducted at the Surgical Department of Sanglah Hospital, Denpasar from January 1st, 2020 to December 31st, 2020. All patients enrolled in this study were calculated with Alvarado, Tzanakis, and RIPASA scores to determine the need for appendectomy. In patients undergoing surgery, the diagnosis of AA was confirmed by histopathological examination. Descriptive analysis, receiver operating characteristics (ROC) analysis, and diagnostic tests were used to assess the effectiveness of the three scoring systems. Results: The total respondents in this study who met the inclusion and exclusion criteria were 103 people. This study found that acute appendicitis was more common in male patients with a mean age of 28.26 years. The RIPASA scoring system has better sensitivity and accuracy than the Alvarado and Tzanakis scores, so it is recommended to use the RIPASA score as a diagnosis of acute appendicitis. However, if an ultrasound facility is available, the Tzanakis score can be used. Conclusion: RIPASA score is the best score to diagnose acute appendicitis.
Validity of predictive score of mortality in peptic ulcer perforation (POMPP) in predicting perforated peptic ulcer mortality operated in Sanglah General Hospital, Denpasar, Bali I Gusti Putu Agung Pratama Putra; Ketut Sudiasa; Tjokorda Gde Bagus Mahadewa
Neurologico Spinale Medico Chirurgico Vol 5 No 1 (2022)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36444/nsmc.v5i1.210

Abstract

Introduction: Peptic ulcer perforation is a non-traumatic emergency that is often encountered and gives a mortality rate of up to 70%. The need for a system that is easy and simple in predicting and screening patients in the initial triage to predict the incidence of mortality after surgery is important. This study aim to test the validity of predictive score of mortality in peptic ulcer perforation (POMPP) in predicting mortality in patients with perforated peptic ulcer surgery. Methods: This study was a diagnostic study with 50 peptic ulcer perforation patients operated between February 2019 to February 2020, and collected with consecutive sampling method. All patients who were operated was calculated for the preoperative POMPP scores, with parameters of age, blood urea nitrogen, and albumin. Patients who were deceased or refused to participate were excluded. The best cut-off point was calculated, then sensitivity, specificity, positive and negative predictive value (PPV/NPV), accuracy of score and POMPP score validity were calculated in predicting post-operative patient mortality. Results: The best cut-off value obtained from receiver operating characteristic (ROC) curve was ≥1.5, where patients with POMPP ≥1 were exposed to a high risk of postoperative mortality (80.8%), and POMPP <1.5 had a low risk of postoperative mortality (19.2%). Other scores were calculated as follow: sensitivity 80.7%, specificity 91.6%, PPV 91.3%, NPV 81.4%, accuracy 86% and the validity test score of 50 patients reached 100%. Conclusion: POMPP has good validity and can be used as a screening tool for patients with perforated peptic ulcer surgery.