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Academia Open
ISSN : -     EISSN : 27147444     DOI : https://doi.org/10.21070/acopen
Academia Open is published by Universitas Muhammadiyah Sidoarjo published 2 (two) issues per year (June and December). This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. This journal aims is to provide a place for academics and practitioners to publish original research and review articles. The articles basically contains any topics research or review. Academia Open is available in online version. Language used in this journal is Indonesia or English. Academia Open is an open access journal publishing scientifically accurate and valuable research across life, physical, social, and medical sciences.
Arjuna Subject : Umum - Umum
Articles 161 Documents
Search results for , issue "Vol 9 No 2 (2024): December" : 161 Documents clear
Assessing Nurses' Knowledge on Medication to Reduce Errors in Iraq Ali, Wasfi Dhahir Abid; Hashoosh, Dhuha Radhi; Mishet, Husain Sameer; Sabri, Samahir Hameed; Atiyah, Maher A.
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10045

Abstract

General background: Administering and preparing medications are fundamental aspects of nursing practice that significantly influence patient outcomes. Specific background: Medication errors during preparation or administration can lead to adverse effects, and assessing nurses' knowledge in this area is crucial for improving patient safety. Knowledge gap: Limited studies have examined the specific knowledge of nurses in Iraq, particularly in Basra hospitals, regarding these practices. Aims: This study aims to assess the knowledge of nurses in Basra Governorate hospitals concerning medication preparation and administration, identifying areas for improvement to enhance patient care. Results: The study surveyed 70 nurses (55.71% female and 44.28% male), with 47.1% holding a BSc in nursing sciences, 28.57% with a diploma, and 24.28% from secondary nursing schools. Regarding experience, 31.42% had less than one year, and 30% had 1-5 years of experience. Participants worked across emergency, internal medicine, surgery, and other departments. Nurses demonstrated a significant mean score of 1.84 in knowledge regarding drug preparation practices and a score of 1.74 in knowledge regarding drug administration, both indicating satisfactory understanding but with variability across departments. Novelty: This study provides specific data on nurses' knowledge in Basra hospitals, a region that has not been extensively studied in the context of medication management errors. Implications: These findings suggest that while nurses possess adequate knowledge of drug preparation and administration, continued education and training, especially for less experienced nurses, may further enhance patient safety. The study highlights the need for targeted interventions in Basra to address gaps in clinical practice and reduce medication errors. Highlights: Medication errors directly affect patient outcomes and treatment effectiveness. Nurses’ knowledge varies by experience and department in Basra hospitals. Continuous training improves medication safety and patient care quality. Keywords: Nursing knowledge, medication errors, drug preparation, drug administration, Basra hospitals.
Rising Cases of Hb H Disease in Iraq Highlight the Urgent Need for Pre-Pregnancy Screening Zaidi, Afak Rasheed Salman
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10066

Abstract

General background: Hemoglobin H (Hb H) disease results from mutations in three of the four α-globin genes, leading to α-thalassemia. Specific background: In Iraq, this condition is rare among alpha-thalassemia cases. The disease presents significant hematological abnormalities, impacting quality of life. Knowledge gap: Despite its rarity, few studies have characterized the hematopathological features and prevalence of Hb H disease in specific Iraqi regions. Aims: This study aimed to assess the hematological parameters and prevalence of Hb H disease among patients in Diyala province, Iraq. Results: A total of 81 patients with Hb H disease (53.18% male, 46.91% female) were registered at the Baqubah Teaching Hospital in 2023. Median patient age was 21.8 years (range 4-48). Hematological analysis revealed consistently low levels of hemoglobin (Hb) and hematocrit (HCT) compared to standard values. Mean corpuscular volume (MCV) was also significantly reduced, with 58.02% of patients presenting Hb levels below 10 g/dL. The 21-40 age group had the highest incidence (46.91%). Novelty: This study is among the few to investigate Hb H disease prevalence and hematopathological characteristics in Diyala province, revealing an unexpectedly high incidence in the 21-40 age group. Implications: These findings suggest that hematological parameters, including MCV and Hb levels, should be considered in thalassemia screening programs, particularly in pre-pregnancy assessments, to prevent the birth of children with severe forms of alpha-thalassemia and reduce Hb H disease prevalence. Highlights: Hb H disease shows low hemoglobin and MCV abnormalities. Highest incidence occurs in patients aged 21-40 years. Pre-pregnancy screening reduces severe alpha-thalassemia risk. Keywords: Hb H disease, alpha-thalassemia, hematological parameters, Diyala province, prevalence
Environmental and Health Impacts Resulting From Burning Solid Waste Near Residential Areas in Diyala Governorate, Iraq Jbara , Abdulwahab Abdulrazaq
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10088

Abstract

General Background: Rapid development, population growth, and improper disposal of municipal solid waste are prevalent issues in developing countries, leading to significant environmental and health challenges. Specific Background: In Iraq’s Diyala Governorate, the absence of integrated waste management exacerbates pollution through waste burning and heavy metal contamination, posing risks to nearby residential areas. Knowledge Gap: While previous studies have addressed waste management in developing countries, there is limited research on how local waste disposal practices impact air, soil, and water quality in specific areas of Diyala. Aims: This study evaluates the air quality and levels of heavy metals in soil and water near five landfill sites in Diyala Governorate: Kanaan, Al-Khalis, Baladruz, Khanaqin, and Hamrin, aiming to assess the pollution levels and the potential health risks to nearby communities. Results: The findings reveal significant differences across the sites, with the highest pollutant concentrations in Kanaan for air (40±445.8), soil (22.18±35.64), and water (3.037±3.146), while Hamrin recorded the lowest concentrations. All sites demonstrated statistically significant differences (P < 0.05). Novelty: This study provides the first comprehensive analysis of the environmental impact of waste disposal practices in Diyala, linking pollutant concentrations with specific landfill sites. Implications: The results underscore the need for improved waste management strategies, including monitoring, waste sorting, and recycling initiatives, to mitigate the negative effects on public health and the environment, particularly in areas near waste dumps. Highlights: Pollution levels vary significantly across Diyala's landfill sites. Kanaan site has the highest air, soil, and water contamination. Better waste management is needed to reduce environmental and health risks. Keywords: Municipal waste, environmental pollution, heavy metals, Diyala Governorate, landfill impact
Protection Effect of Soy Isoflavones (Genistein and Daidzein) on Hematologic Parameters in Acute Kidney Injury Mohammed, Hawraa; Abdullah, Asia S.; AL‑Mozie'l, Muhsin S.G.
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10106

Abstract

Background: Acute kidney injury (AKI) is a severe, high-morbidity condition with limited effective preventative and therapeutic strategies despite advancements in understanding and treatment. Specific Background: Rhabdomyolysis-induced acute kidney injury (AKI) presents significant challenges in renal research, but soy isoflavones, particularly GN and DZ, have shown potential in mitigating oxidative stress and inflammation. Knowledge Gap: Soy isoflavones, while potentially providing renal protection, their impact on renal and hematologic parameters in glycerol-induced AKI models has not been thoroughly studied. Aims: The study evaluated the effectiveness of soy isoflavones in regulating renal and hematologic parameters in a glycerol-induced AKI rat model, assessing their potential as therapeutic agents. Results: The study involving adult female Wistar rats showed that pretreatment with glycerol or dihydroxystilbene significantly reduced urinary β2-microglobulin, albumin, BUN, and serum creatinine levels in the AKI-induced group, reversing hematological changes. Novelty: The study explores the protective effects of soy isoflavones on renal function and hematologic parameters in AKI, highlighting GN's superior efficacy over DZ. Implications: Soy isoflavones, particularly GN, may be potential preventive or therapeutic strategies for AKI caused by rhabdomyolysis, warranting further research for clinical applications. Highlights: GN and DZ reduce kidney damage in glycerol-induced AKI. GN is more effective than DZ in kidney and blood parameters. Soy isoflavones could treat or prevent AKI. Keywords: Acute kidney injury, soy isoflavones, glycerol-induced AKI, renal protection, hematologic parameters
Magnetic Nanocomposites Revolutionize Heavy Metal Adsorption for Environmental Cleanup Waly, Zaynah Salih; Merdas, Samia Mezhr
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10207

Abstract

General background: Magnetic nanocomposites have garnered significant attention due to their multifunctional properties, particularly in environmental remediation, where they can be used for the removal of heavy metals from aqueous solutions. Specific background: Polypyrrole (PPy) and poly(p-hydroxyaniline) (P(p-OH An)) are conductive polymers known for their adsorption capabilities, while Fe3O4 nanoparticles exhibit magnetic properties, facilitating separation and recovery. Knowledge gap: Despite the potential of Fe3O4-based composites, few studies have systematically explored the synergistic adsorption properties of PPy and P(p-OH An) in Fe3O4-based nanocomposites under varying environmental conditions. Aims: This study aimed to synthesize and characterize Fe3O4/PPy/P(p-OH An) magnetic nanocomposites and evaluate their adsorption performance under different temperatures and isotherm models. Results: The nanocomposite was synthesized through chemical oxidation polymerization and characterized using FTIR, TEM, AFM, and TGA, confirming its successful formation and nanoscale structure. Adsorption studies indicated an exothermic process, with a decrease in adsorption capacity at higher temperatures. The adsorption data fit the Freundlich isotherm better than the Langmuir model, suggesting heterogeneous surface adsorption. Novelty: This study demonstrates a novel Fe3O4/PPy/P(p-OH An) nanocomposite with superior adsorption properties, showing its potential in heavy metal ion removal and offering an improved understanding of temperature effects on adsorption performance. Implications: The findings underscore the composite's promise for environmental remediation applications, particularly in water treatment, and suggest further optimization of the adsorption conditions and evaluation of the composite's reusability for industrial-scale applications. Highlights: Enhanced Adsorption: Fe3O4/PPy nanocomposites offer combined magnetic and polymer adsorption properties. Temperature Sensitivity: Adsorption decreases as temperature rises, indicating exothermic behavior. Surface Interaction: Freundlich isotherm shows adsorption occurs on heterogeneous surfaces. Keywords: Magnetic nanocomposite, Fe3O4, Polypyrrole, Adsorption, Environmental remediation.
Critical Knowledge Gap in Blood Transfusion Among University Students in Iraq Mohammad, Noor J.
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10250

Abstract

Background: Blood transfusion, a crucial part of modern medical treatment, is believed to be the first successful organ transplant and plays a vital role in modern healthcare interventions. Knowledge gap: Despite its importance, awareness and knowledge about blood transfusion and donation are insufficient, particularly among university students. Aims: This study aims to assess student knowledge regarding blood transfusion and to raise awareness about blood donation. Methods: A cross-sectional study at Bab Al-Zubair University involved 200 students, assessing blood transfusion knowledge using a questionnaire and SPSS version 16, with statistical analysis. Results: The study revealed that 46% of students had no knowledge of blood transfusion, while only 31% had information on transfusion and donation. Social media was the primary information source for 32% of students, with only 9% undergoing regular blood tests. Moreover, 82.5% of students had never attended a seminar on blood donation. Novelty: This study highlights a significant gap in knowledge and awareness among students regarding blood transfusion and donation, emphasizing the role of social media as a key information source. Implications: The study emphasizes the need for targeted educational interventions in university curricula to enhance student awareness and knowledge about blood donation and transfusion. Highlights: Knowledge Gap: 46% of students lack information on blood transfusion. Seminar Absence: 82.5% never attended blood donation seminars. Educational Need: More training and seminars required to increase awareness. Keywords: Blood transfusion, Student knowledge, Blood donation, Awareness, Cross-sectional study
A Review of Hidradenitis Suppurativa (HS) Kadhum, Eftikhaar Hasan
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10256

Abstract

Background: Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease of the hair follicle, affecting intertriginous areas such as the axillae, perianal, and inguinal regions. It is more prevalent in females, with peak onset between ages 18 and 29. Specific Background: HS, characterized by nodules, abscesses, and sinus tract scarring, uses the Hurley staging system for disease severity classification, but its limitations exist due to its static clinical features. Knowledge Gap: Although several treatment modalities exist, ranging from antibiotics to surgery, there is no definitive therapy, and the pathogenesis remains poorly understood, complicating early diagnosis and management. Moreover, international diagnostic delays of 8-12 years further hinder patient outcomes. Aims: This study aims to explore the limitations of current classification and treatment approaches, while emphasizing the importance of prevention strategies and timely diagnosis to mitigate HS severity. Results: The Hurley classification, though widely used, fails to account for disease progression or quality of life. Current treatment options depend on disease severity, including topical and systemic antibiotics, hormonal therapies, biologics, and surgical interventions. Prevention strategies, such as laser hair removal and lifestyle modifications (e.g., smoking cessation, weight management), are essential to reducing disease impact. Novelty: This research highlights the under-explored role of early prevention and lifestyle interventions in managing HS and reducing progression through Hurley stages. Implications: Enhanced diagnostic tools, combined with early intervention strategies and a holistic approach to patient care, are necessary to improve clinical outcomes, reduce diagnostic delays, and minimize HS-related morbidity. Further research is needed to better understand the genetic and environmental factors contributing to HS pathogenesis. Highlights: HS peaks in females aged 18-29 with chronic skin inflammation. 8-12 years diagnostic delay worsens disease severity and treatment. Prevention: laser hair removal, lifestyle changes reduce HS progression. Keywords: Hidradenitis suppurativa, Hurley staging, inflammatory skin disease, prevention, diagnostic delays
Development of Tetracycline by AgO Nanoparticles and Studying its Activity on Antibiotic-Resistant Bacteria Majeed, Wafaa; Ahmed , Hiba Shihab; Hamed , Zaineb Abd_Alkhalq
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10275

Abstract

General background: Antibiotic resistance in bacteria has become a critical global health issue, necessitating the development of new strategies to enhance antibiotic efficacy. Specific background: Nanoparticles, particularly silver nanoparticles (AgNPs), have emerged as potential enhancers of antibiotics due to their unique properties and interactions with bacterial cells. Knowledge gap: However, the combination of nanoparticles with existing antibiotics, such as tetracycline, and their impact on bacterial inhibition and safety has not been fully explored. Aims: This study aims to investigate the antibacterial activity of silver oxide nanoparticles (AgO NPs) combined with tetracycline (TCS) and evaluate their effectiveness against resistant bacterial strains. Results: AgO NPs were synthesized using a photodeposition method, yielding nanoparticles with an average diameter of 2.24 nm. The AgO NPs + TCS combination demonstrated superior antibacterial activity, with a minimum inhibitory concentration (MIC) of 16 μg/mL against Staphylococci and 32 μg/mL against Pseudomonas aeruginosa, significantly outperforming standard tetracycline. Hemolysis assays confirmed the safety of the synthesized compound at all concentrations. Novelty: Silver oxide nanoparticles and tetracycline exhibit a unique synergistic interaction, enhancing antimicrobial effects by increasing bacterial membrane permeability, facilitating greater antibiotic infiltration. Implications: These findings suggest that AgO NPs combined with tetracycline offer a promising solution to overcome bacterial resistance, providing a potent and safe alternative to conventional antibiotic treatments. Highlights: AgO NPs and tetracycline show enhanced antibacterial effects. More effective than standard tetracycline against resistant bacteria. Safe with no toxicity observed in hemolysis tests. Keywords: Antibiotic resistance, silver nanoparticles, tetracycline, photodeposition, antibacterial activity
Quality of Life in Patients with Knee Osteoarthritis: A Cross-Sectional Study in Baaquba City Najim , Akram Abd Alsalam; Faleh , Ali Husain; Noaman , Aqeel Abbas
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.10279

Abstract

Background: Knee osteoarthritis (KOA) is a common degenerative joint disease that significantly impacts the quality of life (QoL) of elderly individuals, often leading to severe disability. Specific Background: KOA, a prevalent condition primarily affecting middle-aged women, is exacerbated by risk factors like obesity, genetics, and reduced physical activity. Knowledge Gap: Despite existing studies on KOA, there is limited research on its impact on QoL in the Iraqi context, particularly in Baqubah City. Aims: The study evaluated the quality of life (QoL) of KOA patients in Baqubah, Iraq, considering physical, psychological, social, and functional aspects, and identifying influencing factors. Results: Data were collected from 374 patients at Baqubah Teaching Hospital, using a structured and validated HRQOL questionnaire. The study revealed that KOA patients experienced a significantly reduced QoL, especially in the physical and functional domains. Females and those with a longer illness duration reported worse outcomes. Obesity and overweight were found to be common among patients, further exacerbating the disease. Novelty: This study evaluates KOA's impact on QoL in Baqubah, revealing high prevalence and significant negative effects on daily activities. Implications: The study highlights the need for targeted interventions to enhance the quality of life for KOA patients in Baqubah, focusing on weight management, physiotherapy, and improved public health strategies. Highlights: KOA severely impairs physical and functional quality of life in patients. Obesity and inactivity are key modifiable risk factors for KOA. Women and long-term sufferers face greater QoL challenges. Keywords: Knee Osteoarthritis, Quality of Life, Risk Factors, Obesity, Baqubah
Tonsillectomy in Children: Review Article Awad, Kadhim Jawad
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.10.2025.10602

Abstract

One of the most frequent surgical operations on children in Australasia is tonsillectomy. For a non-surgical audience, this study attempts to give a current evaluation of the procedure's indications (and the evidence basis for each of these indications), together with a discussion of the surgical technique, perioperative care, and risks. Recurrent pharyngotonsillitis and obstructive sleep apnea (OSA) are the main causes of tonsillectomy; tonsillectomy is typically done in combination with adenoidectomy for both conditions. Tonsillectomy has been shown to enhance quality of life, child behavior, and objective measurements of OSA in sleep studies. It is less clear how surgery affects cognitive function. Highlights: Common pediatric surgery: Tonsillectomy for recurrent pharyngotonsillitis & obstructive sleep apnea. Benefits: Improves quality of life, behavior, and OSA measurements. Uncertainty: Cognitive effects of surgery remain unclear. Keywords: Tonsillectomy, Children, Review