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Contact Name
Novena Yety Lindawati
Contact Email
novena_yl@yahoo.com
Phone
+62271-572339
Journal Mail Official
ojs.stikesnas@stikesnas.ac.id
Editorial Address
LPPM STIKES Nasional Jl. Raya Solo-Baki, Kwarasan, Grogol, Sukoharjo, Jawa Tengah 57552
Location
Kab. sukoharjo,
Jawa tengah
INDONESIA
Jurnal Farmasi
ISSN : 23027436     EISSN : 26568950     DOI : https://doi.org/10.37013/jf
Core Subject : Health,
JURNAL FARMASI (Journal Of Pharmacy) adalah jurnal ilmiah resmi yang dikeluarkan oleh Sekolah Tinggi Ilmu Kesehatan Nasional dengan nomor p-ISSN 2302-7436 e-ISSN 2656-8950. JURNAL FARMASI (Journal Of Pharmacy) berisikan jurnal-jurnal ilmiah dalam semua aspek ilmu pengetahuan dan teknologi di bidang Farmasi dan kesehatan antara lain: Farmakognosi dan Fitokimia meliputi Pengembangan Simplisia, Budidaya Tanaman Obat, Isolasi, Skrining Fitokimia, dan Identifikasi Obat Bahan Alam Indonesia. Biologi meliputi Biologi Molekuler, Bioteknologi, Mikrobiologi, Immunologi, Parasitologi, Biomedisinal Teknologi Farmasi meliputi Farmasetika, Teknologi dan Formulasi Sediaan Obat, Teknologi dan Formulasi Sediaan Obat Bahan Alam Indonesia. Ilmu Kimia meliputi Kimia Analisa, Kimia Organik, Sintesa Obat, Kimia Medisinal, Pemodelan Molekul, Biokimia, dan Kimia Lingkungan. Farmakologi meliputi Farmakologi, Farmakokinetik, Farmakoterapi, dan Toksikologi. Farmasi Klinik dan Komunitas meliputi Farmakoekonomi, Farmakovigilan, Analisis dan Evaluasi Penggunaan Obat, Monitoring Efek Samping Obat, Analisa Kebijakan Kefarmasian, Evaluasi kegiatan Kefarmasian, Evaluasi Efektifitas Penggunaan Obat, Evaluasi Kualitas Hidup Pasien.
Articles 5 Documents
Search results for , issue "Vol 2, No 1 (2021): PROCEEDINGS ICHC" : 5 Documents clear
The Effect Of Different Solvent Extraction On Chemical Content And Quercetin Levels Of Ketapang (Terminalia cattapa L.) Erma Yunita; Erlinda Mula Destasary; Fa’iz Helmi Wicaksana
Jurnal Farmasi (Journal of Pharmacy) Vol 2, No 1 (2021): PROCEEDINGS ICHC
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v2i1.157

Abstract

Ketapang has flavonoid content that is quercetin. The appropriate solvent can attract the active compound of quercetin on ketapang. The selection of solvents adjusts different levels of polarity with the aim of obtaining the best solvent. This study aims to determine the difference between extraction solvents to the quercetin levels of ketapang leaves.Simplisia leaves of ketapang made by winding. Maceration is carried out on ketapang leaves using 3 different solvents namely n-hexane, ethyl acetate, and ethanol 90%. The viscous extract obtained was analyzed for yield value and the phytochemical screening test was do qualitatively. Quercetin level measured by UV-Vis Spectrophotometry at a maximum wavelength of 375.6 nm. The absorbance value obtained is entered into the standard quercetin curve equation with the equation y=0.0885x+0.0037.The results of the yield value of ketapang leaf extracts with each different type of solvent resulted in different yield values, as well as the results of phytochemical screening and percent quenching levels obtained.Keywords: Terminalia cattapa L., Yield Extract, Phytochemical, Quercetin
The Effect of Pare (Momordica Charantia) L. Ethanol Extract on The Formation of Cataracts in Wistar White Rats Nur Rahayuningsih; Desi Agni Mutia; Tita Nofianti
Jurnal Farmasi (Journal of Pharmacy) Vol 2, No 1 (2021): PROCEEDINGS ICHC
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v2i1.158

Abstract

Cataract is a clouding of the lens of the eye that reduces the amount of light entering and results in impaired vision. Cataracts remain the leading cause of visual impairment and blindness worldwide. Bitter melon fruit contain flavonoids and polyphenols which have antioxidant activities. Thirty of 9 days age wistar rats was divided into six group. Normal and negative group were given 2 ml/200 g BW rats 1% of PGA orally. Positive control was given 0,0009 g/200 g BW rat of vitamin C. Test group 1, 2, and 3 (were given 0,025 g/200 g BW rats; 0,051 g/200 g BW rats; and 0,1 g/200 g BW rats bitter melon fruit ethanol extract orally, respectivelly). All of the group except Normal were inducted with 0,25 mg/200 g BW rats sodium selenit subcutaneously. Treatment was given until the rat open the eyes for the first time (± 18 days). Eyes were observed macroscopic and microscopically in all group. The ethanol extract of bitter melon (Momordica charantia L.) has preventive activity against the formation of cataracts. The negative control group and dose I included in stage IV, positive control included in stage I, dose II included in stage III and dose III included in stage II. The most effective dose which prevent the formation of eye cataracts was 0,1 g/200 g BW rats bitter melon fruit (Momordica charantia L.) ethanol extract.Keywords : Cataract, Bitter melon fruit, flavonoids
Bacterial Cell Wall Synthesis Inhibition Of Clerodendrum Squamatum Vahl. Phytoconstituents: A Molecular Insight Marko Jeremia Kalalo; Elly Juliana Suoth; Irma Antasionasti; Sri Sudewi; Billy Johnson Kepe; Fatimawali Fatimawali
Jurnal Farmasi (Journal of Pharmacy) Vol 2, No 1 (2021): PROCEEDINGS ICHC
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v2i1.159

Abstract

Bacterial Cell Wall (BCW) is an essential part of bacteria. Defects in BCW may lead to bacterial death due to failure in maintaining pressure and cell integrity or shape. Penicillin-Binding Protein (PBP) 2a, 1, 2, 3, and 4 are proteins responsible for Methicillin-Resistant Staphylococcus aureus (MRSA) cell wall synthesis. MRSA is a hard-to-treat bacteria due to its antibiotic resistance. Clerodendrum squamatum Vahl. leaves (CSVL) are used by North Sulawesi-Indonesian people as a medicinal plant to treat inflammation and to heal wounds. So, the present study aims to explore CSVL potential as inhibitors of MRSA cell wall synthesis using in silico approach. CSVL phytoconstituents were analyzed using Gas Chromatography-Mass Spectroscopy (GC- MS), and the chemical structures were retrieved from PubChem and docked to PBP2a, PBP1, PBP2, PBP3, and PBP4 using Pyrx-Vina. The toxicity profile of the phytoconstituents was also calculated. The results showed that CSVL interacts with PBPs with a variety of types of bonding, dominated by hydrogen bonds. The toxicity prediction showed that CSVL has a safe toxicity profile. CSVL can be a good anti-MRSA candidate due to its molecular interactions with BCW synthesis proteins.Keywords: MRSA, antibiotic resistance, medicinal plant, PBPs 
The Influence of Education with Audio-Visual Media on Adolescent Knowledge Level in Kaligentong Village, Gladagsari, Boyolali, Central Java About Preventing of COVID-19 Transmission Eka Pratiwi; Lusia Murtisiwi
Jurnal Farmasi (Journal of Pharmacy) Vol 2, No 1 (2021): PROCEEDINGS ICHC
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v2i1.160

Abstract

In early 2020, the World Health Organization announced Corona Virus Disease-19 (COVID-19) had become a global pandemic. The spread of COVID-19 is very fast and widespread because it is transmitted human to human. Knowledge about preventing the transmission of COVID-19 is very important to reduce the increase in spread of COVID-19, including among adolescents. This study aims to analyse the influence of education with audio-visual media on the level of knowledge of adolescents in Kaligentong Village, Gladagsari, Boyolali regency, Central Java about preventing the transmission of COVID-19. This is a quasi-experimental study with a non-randomized pretest-posttest design with control group. Sampling was done by purposive sampling. The data collection technique was carried out using a questionnaire that was given online using Google form. Respondents in this study were adolescents aged 15-24 years and unmarried, as many as 82 respondents who were divided into two groups, namely the control group and the intervention group. Data were analysed by Wilcoxon, Mann Whitney and intervention effect tests. The results on this study indicate the influence of education through audio-visual media on the level of knowledge of adolescents in Kaligentong Village, Gladagsari, Boyolali about preventing the transmission of COVID-19 with an effect size of 72,3% and shows a significant difference between the experimental group and the control group.Keywords: COVID-19 prevention, adolescents, education, audio-visual media, level of knowledge
Activities Formulation of Jackfruit (Artocarpus Heterophyllus Lamk) and Moringa (Moringa Oleifera) Leaf on Antidiabetic in Vivo Joko Santoso; Atiek Murhayati; Irma Erinda Nur Pratiwi
Jurnal Farmasi (Journal of Pharmacy) Vol 2, No 1 (2021): PROCEEDINGS ICHC
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v2i1.161

Abstract

Indonesia ranks sixth in the world for the highest prevalence of diabetes after China, India, the United States, Brazil, and Mexico. The prevalence of people with diabetes in Indonesia tends to increase, where in 2007 it was 5.7% and in 2013 it was 6.9%. In 2045, the number is estimated to be 16.7 million people with diabetes aged 20-79 years. Jackfruit leaves (Artocarpus heterophyllus Lamk) contain phytochemical compounds, active compounds of flavonoids, tannins, saponins, alkaloids, polyphenols, steroids, where these compounds can reduce blood glucose levels. Jackfruit leaves and Moringa leaves contain flavonoids, tannins, alkaloids, triterpenoids, saponins, and reducing sugars showed that flavonoids have a hypoglycemic effect. Objective To evaluate the activity of the jackfruit and moringa leaf formulations against antidiabetic in vivo. Methods The research used experimental methods with a post test design laboratory research approach where this study was divided into 5 experimental groups, each group consisting of 5 test animals. Results: Tests for blood sugar levels in rats were Group I (ENK 200mg/kgBW) of 110.30 mg/dL, Group II (ENK 400mg/kgBW) of 100.50 mg/dL, Group III (ENK 800mg/KgBW) of 95.50 mg/dL, Group IV (Glibenclamide 150mg/KgBW) of 120, 30 mg/dL and Group V (Aquadest) of 190.30 mg/dL. Conclusion: The effective dose and activity as antidiabetic is group III ( ENK 800mg) because it can reduce blood sugar levels by 95.50 mg/dL compared to other groups.Keywords: Jackfruit leaves, Moringa and Antidiabetes

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