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INDONESIA
GANESHA MEDICINA
Published by Universitas Pendidikan Ganesha
ISSN : -     EISSN : 27978672     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Ganesha Medicina Journal is open access; double-blinded peer-reviewed journal aiming to communicate high-quality research articles, case report, reviews and general articles in the field. Ganesha Medicina Journal publish articles that encompass all aspects of basic research/clinical studies related to the field of medical sciences. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship, and to encourage a vigorous dialogue between medical scholars and practitioners.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 83 Documents
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Comparative Efficacy and Safety of Topical Calcineurin Inhibitors Versus Low-Potency Corticosteroids in Atopic Dermatitis: A Systematic Review and Meta-Analysis Putri Indrasuari
Ganesha Medicina Vol. 6 No. 2 (2026):
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/gm.v6i2.113924

Abstract

Atopic dermatitis is a chronic inflammatory skin disease commonly treated with topical corticosteroids, which are limited by adverse effects in sensitive areas. Topical calcineurin inhibitors have emerged as steroid-sparing alternatives. This study compares the efficacy and safety of topical calcineurin inhibitors versus low-potency topical corticosteroids in atopic dermatitis. A systematic review and meta-analysis of randomized controlled trials was conducted following PRISMA guidelines. PubMed, Cochrane Library, and ScienceDirect were searched. Outcomes included clinical efficacy and safety (skin atrophy and burning). Pooled risk ratios (RR) with 95% confidence intervals (CI) were calculated using a random-effects model. Six studies were included in this study. There was no significant difference in efficacy between groups (RR = 1.03, 95% CI: 0.80–1.32; p = 0.82; I² = 93%). Calcineurin inhibitors significantly reduced the risk of skin atrophy (RR = 0.12, 95% CI: 0.02–0.63; p = 0.01; I² = 0%). However, they were associated with a higher incidence of skin burning (RR = 3.08, 95% CI: 1.22–7.80; p = 0.02; I² = 97%). Calcineurin inhibitors provide similar efficacy with superior structural safety but lower tolerability due to increased local irritation. In conclusion, calcineurin inhibitors represent a safe and effective alternative to corticosteroids, particularly for sensitive areas and long-term management.
Development of the “SI KIMUL” Application (Oral and Dental Health System) for Elementary School Students Arisya Pramesti Putri; Putri Rejeki; Desak Ayu Dhyana Nitha Dewi; Eko Sri Yuni Astuti
Ganesha Medicina Vol. 6 No. 2 (2026):
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/gm.v6i2.113968

Abstract

Dental and oral health are essential components of overall health. In Bali Province, 46.5% of the population experiences oral and dental health problems, while Denpasar City ranks third among cities in Bali at 40.66%. This study aimed to develop the “Si Kimul” (Oral and Dental Health System) application as a health promotion medium for elementary school students and to evaluate its feasibility. The study was conducted at SD Negeri 12 Sesetan, Denpasar, Bali, using a Research and Development (R&D) approach consisting of eight stages. The sample consisted of 82 students from grades I–VI, selected using stratified random sampling. Data were collected using expert validation questionnaires, product trial questionnaires, and usability testing questionnaires, then analyzed quantitatively using Likert and Guttman scales. The results showed that material expert validation reached 92.25% and display expert validation reached 85.16%, both categorized as “Highly Feasible.” Product testing resulted in 88.86%, while usability testing reached 91.46%, also categorized as “Highly Feasible.” These findings indicate that the “Si Kimul” application is feasible as a digital health promotion medium to support oral and dental health education among elementary school students. Further development is recommended to improve cross-platform accessibility and broader implementation.  
Ogilvie’s Syndrome in A Young Adult with HIV Infection: A Case Report I Made Gede Dwipayana Putra; Ketut Suryana
Ganesha Medicina Vol. 6 No. 2 (2026):
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/gm.v6i2.114043

Abstract

Acute colonic pseudo-obstruction, known as Ogilvie’s syndrome, is a condition characterized by acute colonic dilation in the absence of mechanical obstruction. Primary clinical feature is abdominal distension. Abdominal pain is present in 80% of cases, followed by nausea and vomiting in approximately 60%. Diagnosis can be found from clinical symptoms, laboratory tests, and radiological imaging. Plain abdominal X-ray is a good diagnostic tool. A 27-year-old male patient was hospitalized at district hospital with complaints of fever for 2 days before admission, previously fever for 2 weeks, accompanied by abdominal pain, inability to fart and defecate in the last 4 days, abdominal distension previously existed. Laboratory examination found anemia, leukopenia, thrombocytopenia, hyponatremia and hypokalemia. Plain abdominal X-ray examination found a colonic dilatation with an impression of adynamic ileus. Ogilvie’s Syndrome is a clinical condition characterized by abdominal distension and dilation of the colon. This condition can occur at younger age, especially in those with serious medical conditions or a history of surgery. In this 27-year-old male patient, he had a serious medical condition, HIV, which caused a compromised immune system, which could be the reason of Ogilvie’s Syndrome. HIV/AIDS is a chronic immune system disorder that causes various multi-organ manifestations, has very serious consequences and can develop to Ogilvie’s Syndrome.

Page 9 of 9 | Total Record : 83

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