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Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga.
Published by Universitas Muhammadiyah Malang
ISSN : 0216759X     EISSN : 2614476     DOI : https://doi.org/10.22219/
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Journal of Saintika Medika is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Letters and commentaries of our published articles are welcome.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 10 Documents
 1 
Search results for , issue "Vol. 17 No. 1 (2021): June 2021" : 10 Documents clear
Hypoxic Status Is Associated With The Intensity Of Hypoxia Inducible Factor (Hif)-1α Expression In A Premature Placenta Kartini Edwin
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.11685

Abstract

Prematurity refers to live births before 37 weeks of gestation and associated with infant morbidity/mortality. Activation of HIF during the final pregnancy phase is believed to play a critical role in the pathogenesis of premature birth and other pregnancy disorders. This study aimed to analyze the relationship between hypoxicstatus and the intensity of HIF-1α expression in a premature placenta.Stored biological materials premature placenta (paraffin blocks) was used in this study. Thirtyone samples of placental hypoxia (H) and 28 samples of premature placental non-hypoxia (N) as controls, were selected non-random consecutively. Subsequently, immunohistochemistry was performed to analyze HIF-1α expression. TheChi-square testwas used to analyze the data and a p-value <0.05 was considered statistically significant.Moderate to strong intensity of HIF-1α expressionwas observed in 58% of hypoxic placenta samples, whereas most of non-hypoxic placental samples(86%) did not expressed or expressed weaklyHIF-1α.There was a significant correlation between the intensity of HIF-1α expression and placental hypoxia (p <0.05) and Odds Ratio (OR) value was 8.31 with a 95% confidence interval (2.32-29.77). The conclusion shows that hypoxic status is associated with intensity of hypoxia inducible factor (HIF)-1α expression in a premature placenta.
Effect Of Recovery Time After Match On Muscle Explosive Power On Football Athletes Adelia Handoko; Cahyo Bagaskoro
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.12092

Abstract

Football is one of the most prestigious forms of sports that are in great demand by the public. Many football clubs that take part in the competition have a tight match schedule. This causes the recovery time for athletes to be short and lead to fatigue. The purpose of this study was to determine the effect of recovery time after the match on the explosive power of leg muscles in soccer athletes. This study was an experimental study with a pretest-posttest group design. The sampling method used was simple random sampling to get 40 research subjects divided into 2 groups, namely groups with recovery time of 2 days and groups with recovery time of 5 days. The assessment used is measurement of explosive limb muscle power using the vertical jump technique before and after receiving the recovery period. To test the normality of data using Shapiro-Wilk continued with the comparative data test in the form of an unpaired t test. The results of the study in groups with a recovery time of 2 days were worth -3.7cm and the group with a recovery time of 5 days was 2.9cm. These results were analyzed using unpaired t-test showing p value = 0,000 (p<0.05) which showed there were significant differences between the two groups. The conclusion of this study is that there is an effect of recovery time after the game on the leg muscle explosive power in soccer athletes. Recovery time of 5 days is better than 2 day after competition. It is very important to pay attention to recovery time in athletes, the recommendation of this study is a minimum of 5 days.
Kebar Grass Extract (Biophitum Petersianum) Increases Diameter Of The Seminiferous Tubules Of Diabetic Mice Faraida Arvilla
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.12150

Abstract

Diabetes is a metabolic disease that can affect the male reproductive system. The condition of hyperglycemia will increase the production of ROS, causing oxidative stress. Oxidative stress causes microangiopathy, triggers cell apoptosis, interferes with spermatogenesis, thereby affecting the diameter of the seminiferous tubules. Kebar grass contains of flavonoid and vitamin E which can be used to reduce ROS reactions and inhibit oxidative stress. This research was to prove that kebar grass extract can increase diameter of the seminiferous tubules of diabetic mice. Total of 30 samples were divided into 5 groups: negative control group (K-) was given CMC-Na, positive control group (K+) was given metformin 2mg/kg, groups P1, P2 and P3 received 2mg/kg metformin and kebar grass extract with different dosages (67.5mg/kg, 135mg/kg and 270mg/kg). The treatment lasted for 35 days. On the 36th day the mice were sacrificed and the testes were taken, then histological observations were made with HE staining to measure the diameter of tubules. The result showed that there was a significant difference in the diameter of seminiferous tubules with p value=0,000. Kebar grass extract can increase the diameter of seminiferous tubules of diabetic mice.
Correlation : Anatomical Variations of Nasal Cavity and Paranasal Sinuses and the Quality of Life Based on SNOTT-22 Score Rani Rahmawati
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.13763

Abstract

This study aims to determine the correlation between the anatomical variations of nasal cavity and paranasal sinuses and the quality of life based on SNOT-22 score in the patients who underwent paranasal sinuses CT scan. The samples are 36 patients with age ≥ 18 years. The method is Chi Square test / Fisher's test and Spearman’s rho test. The results showed that anatomical variations of the nasal cavity and paranasal sinuses from most of the patients who underwent paranasal sinuses CT scan had septal deviation n = 29, p = 0.007 (p <0.05) and concha bullosa n = 15, p = 0.029 (p <0.05). There was a significant correlation between total anatomical variation and quality of life based on SNOT-22 score in the patients who underwent paranasal sinuses CT scan p = 0.025 (p <0.05). There was no correlation between the anatomical variations of frontal cells, agger nasi cells, ethmoid bulla, uncinate process and haller cells and the quality of life based on SNOT-22 score in the patients who underwent paranasal sinuses CT scan.  
Body Mass Index and HbA1c Are Associated with Renal and Hepatic Function Yoga Mulia Pratama; Falah Faniyah; Imam Nafiyana Saputra
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.15102

Abstract

Hypertension and diabetes may have implications for damage to other organs such as the kidneys and liver which are evaluated by serum creatinine and ALT, respectively. This study aims to delineate the association between body mass index and hbA1c with renal and hepatic function, respectively. This is a cross-sectional study involving 32 subjects. The research subjects consisted of diabetics and hypertension who were registered in the Muhammadiyah Primary Health Care, Kebanaran, Purwokerto. It was found that in diabetics, there were significant results between serum creatinine and HbA1c values (p <0.01, r = 0.855). Systolic blood pressure was correlated with body mass index (BMI) (p <0.01, r = 0.649). In patients with hypertension, serum creatinine was correlated with the length of time a person has hypertension (p <0.01, r = 0.475). Meanwhile, the ALT value was correlated with body mass index (p <0.05, r = 0.422) and waist circumference (p <0.001, r = 0.528). We found that a decreased HbA1c levels significantly reduces serum creatinine levels so it may also reduce kidney damage. A decrease in the value of BMI and waist circumference significantly reduces ALT enzyme levels which may have the potential for reducing liver damage.
Analisis AIDS Stigmation of Adolescents In Medan City Putra Apriadi Siregar
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.15213

Abstract

AIDS is a disease that is still high in all parts of the world, including Indonesia. Gender is a factor in the occurrence of stigmatization in adolescents. This study aimed to determine the stigma factor for HIV/ AIDS among adolescents in Medan City. This research is a quantitative descriptive study using a cross-sectional study design with a quantitative approach. This research was conducted in Medan City conducted from August to December 2020. The data source in this study was primary data obtained from interviews. Collecting data by direct interviews using a structured questionnaire. Analysis of the data in this study using descriptive analysis and crosstab using the SPSS version 22 program. The results showed that as much54 girls do not want to swim in the same swimming pool as HIV/ AIDS, 55 girls do not want to eat/drink a plate with HIV/ AIDS, 46 girls do not want to use the toilet with HIV/ AIDS, 36 girls do not want to touch their skin with HIV/ AIDS. HIV/ AIDS, 52 teenagers do not want to sleep together with HIV/ AIDS, and 57 young women do not want to wear the same clothes as HIV/ AIDS. It was concluded that female adolescents are more likely to stigma on people living with HIV/ AIDS than male adolescents. It is necessary to carry out socialization and health education to adolescents to eliminate the stigmatization of HIV/ AIDS.
Cardioprotectant Effect Of Bay Leaf Extract (Syzygiumpolyanthum) On Myocardium Thickness Of Rat Heart Dian Yuliartha Lestari; Rizky Trimaulidia
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.15803

Abstract

High salt diet and prednisone administration will increase blood pressure which chronically causes heart muscle remodeling so that it appears macroscopically as left ventricular hypertrophy. Bay leaf extract contains flavonoids which can lower blood pressure and decrease left ventricular thickening. To determine the effect of bay leaf extract (Syzygiumpolyanthum) on the left ventricle thickening of rat heart (Rattus norvegicus wistar strain) in hypertensive model.  True experimental post-test only controls group design with simple random sampling technique. The subjects of this study were 25 male Wistar rats aged 2-3 months weighing 150-200 grams. Rats were induced with prednisone 1.5 mg/ KgBW / day in 2% NaCl for 6 weeks followed by administration of bay leaf extract at a dose of 70 mg/ KgBW, a dose of 140 mg/ KgBW, and a dose of 280 mg/ KgBW. Data analyzed by One Way ANOVA, Post Hoc Bonferroni, followed by Linear: One Way ANOVA test showed significant differences between treatments (p = 0.000). The Bonferroni Post Hoc test concluded that there were significant differences in the treatment of the P2 and P3 groups. Linear regression test obtained R square 0.663 and obtained the equation Y = 1965.838 - 1.275X. The extract of bay leaf (Syzygiumpolyanthum) has an effect on decreasing the left ventricle thickening of the white male rat heart (Rattus norvegicus wistar strain) hypertension model.
Relationship Of Nutritional Components In Toddlers Aged 25-59 Months To Stunting And Short Stature Incidents In Pragaan District, Sumenep Regency Pertiwi Febriana Chandrawati; Conita Walida Sabrina
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.15872

Abstract

Stunting and short stature are height per-age <-2SD for specific age and gender. The process of stunting and short stature starts from the womb until the beginning of life. The direct cause of stunting is the lack of nutritional intake in the first 1000 days of life, which can inhibit height growth. Study aimed to investigate the association between the relationship of nutritional components in toddlers to stunting and short stature incidents in Pragaan District, Sumenep Regency. Observational analytic with a case-control approach, using the Purposive-Sampling method. The research sample consisted of 76 toddlers aged 25-59 months. The statistical analysis used was the chi-square test and logistic regression test. The result of chi-square test and logistic regression for stunting on nutrient intake variable ( p = 0.000, OR = 26,3, CI 95% (4,630-153,573), history of breastfeeding (p=0,000, OR=72,6,CI95% (7,63-690,78), iodized salt (p=0,000, OR=8,5,CI 95% (1,833-39,421), FE tablet (p=0,000,OR=37,00, CI 95%(3,762-363,91). The result of chi-square test and logistic regression for short stature on nutrient intake variable (p=0.001, OR=7,2,CI 95% (2,260-23,400), history of breast feeding (p=0,007, OR=4,500,CI 95% (1,210-16,742), iodized salt (p=0,007, OR=19,125, CI 95% (5,062-72,259), FE tablet (p=0,149). There is a relationship between nutritional components intakes such as breastfeeding history and iodine salt consumption with stunting and short stature in Pragaan District, Sumenep Regency.
Maxillary Rhinosinusitis Profil In General Hospital Of Haji Surabaya On January-December 2017 Indra Setiawan
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.16009

Abstract

Chronic rhinosinusitis in various countries in the world and Indonesia shows an increase from time to time. At General Hospital of Haji Surabaya, the prevalence of chronic rhinosinusitis has increased from 10.13% in 2016 to 10.26% in 2017. Various factors are thought to cause chronic rhinosinusitis. Chronic rhinosinusitis can interfere with the quality of life and lead to serious complications if left untreated. To determine the profile of chronic rhinosinusitis in General Hospital of Haji Surabaya for January-December 2017 Period. Analytic observational with cross-sectional study approach. Used the total sampling method. Based on patients diagnosed with chronic rhinosinusitis with complete medical record data. The sample in this study were 132 patients. Most chronic rhinosinusitis patients were aged 36-45 years as many as 26 patients (19.69%) and the least number of patients was more than 65 years old as many as 6 patients, women (67.40%) and 43 patients in men (32, 60%). Symptoms of nasal congestion in 79 patients (59.84%), cough as many as 25 patients (18.93%), septal deviation as many as 51 patients (38.63%) and at least 4 patients (3.03%) of nasal polyps. Most rhinosinusitis patients in this study were aged 36-45 years, women with symptoms of nasal congestion and septal deviation as the most comorbidities.
Risk Factors for Incidence of Intrauterine Fetal Distress in Hospital of Pamekasan Mochamad Ma'roef
Saintika Medika Vol. 17 No. 1 (2021): June 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM1.16452

Abstract

Fetal distress during intrauterine is related to many factors. Knowing the risk factors will provide an effort to prevent and detect early fetal distress cases. The objective was to determine the risk factors for fetal distress during intrauterine treatment at dr. H. Slamet Martodirdjo Pamekasan. The method used is analytic observational with a cross-sectional method and the sample is simple random sampling. Samples taken were 184 patients in the delivery room dr. H. Slamet Martodirdjo general hospital Pamekasan. Data was taken by observation from patient medical records during 2018. Through this study, 92 patients experienced intrauterine fetal distress. The main risk factors for fetal distress was umbilical cord twists (p: 0.003, OR: 6,857, 95% CI: 1,914-24,572) and protective factors were maternal anemia (p: 0.018, OR: 0.141, 95% CI : 0.028-0.714). There are several risk factors for fetal distress during the intrauterine process at dr. H. Slamet Martodirdjo Pamekasan, the main factor was umbilical cord twisting where pregnant women with umbilical cord twists have a 6 times risk of experiencing fetal distress compared to those who do not.

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