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Muammar Fawwaz
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Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy Universitas Muslim Indonesia, Jl. Urip Sumohardjo KM 5 Kampus II, Makassar 90231, Indonesia
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Pharmaceutical Reports
Published by Universitas Muslim Indonesia
ISSN : 28286030     EISSN : 28288734     DOI : https://doi.org/10.33096/pharm%20rep.v1i2
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
Pharmaceutical Reports is a peer-reviewed journal published by the Pharmaceutical Chemistry Laboratory of the Faculty of Pharmacy, Universitas Muslim Indonesia, which was first published in 2022. We published two times a year in January-June and July-December. Our mission is to advance the science and practice of pharmaceutical research by working to develop and maintain competence, ethics, and integrity, and the highest professional standards in the specialty for the benefit of the public. Pharmaceutical Reports publishes studies that contribute to an understanding of some specific areas in pharmaceutical sciences including the following: - Analytical chemistry of organic and natural product compounds using instrumental analysis in pharmaceutical sciences including spectroscopy and chromatography method. - Design, synthesis, and biological evaluation of biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools. - Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). - Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds. - Pharmaceutics & Biopharmaceutics - Novel & Targeted Drug Delivery - Pharmacology & Toxicology - Pharmaceutical Biotechnology & Microbiology - Pharmacy Practice & Hospital Pharmacy - Drug Regulatory Affairs
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 7 Documents
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Search results for , issue "Vol 3, No 1 (2024): (March) Pharmaceutical Reports" : 7 Documents clear
Identification of Formalin in Raw Tofu from Sidenreng Rappang District Traditional Markets Hasrianti, Hasrianti; Suhaenah, Asriani; Pratama, Mamat
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.290

Abstract

Formalin (Formaldehyde) is a chemical compound whose use is prohibited as a preservative in food additives. This study aims to analyze the content of formalin (Formaldehyde) in raw tofu circulating in Sidenreng Rappang district. The test method used was by qualitative analysis using Schiff reagent and KMnO4. The quantitative analysis using the UV-Vis spectrophotometry method. The test results used Schiff reagent and KMnO4, the four tofu samples contained formalin. Test results on the UV-Vis Spectrophotometry method at a wavelength of 555 nm, obtained formalin levels in sample with sample code A = 1.130%, sample code B = 1.826%, sample code C = 1.84%. It can be concluded that in the formaldehyde qualitative analysis test on raw tofu, the three samples positively contained formaldehyde. As well as the results of the measurement of the three positive samples containing formaldehyde using a UV-Vis spectrophotometer.
Antioxidant Activity of Dechlorophyllation of Kejibeling Leaf (Strobilanthes crispu L.) Extract Using the Free Radical Reduction Method Marda, Marda; Naid, Tadjuddin; Rahmawati, Rahmawati
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.285

Abstract

Kejibeling leaves (Strobilanthes crispus L.) from the Acanthaceae family is a medicinal plant that has medicinal properties. This research aims to determine and determine the antioxidant activity of the dechlorophyllation ethanol extract of kejibeling leaves (Strobilanthes crispus L.) based on the IC50 value with the DPPH method. Kejibeling leaf extract (Strobilanthes crispus L.) extracted by soxhletation method, wherein the extraction process uses two types of solvents of different polarity, to attract chlorophyll compounds and antioxidant compounds, the percent yield of chlorophyll extract is obtained 0.0352% and percent yield of dechlorophyllation ethanol extract 9.604%. Then tested the antioxidant activity using the DPPH method. The results showed that there was antioxidant activity with an IC50 value of 106.375 µg/mL, that is, the result shows moderate antioxidant activity, while quercetin as a comparison has very strong antioxidant activity with a value of 1.391 µg/mL.
Formulation and Evaluation of Anti-Acne Activity of Gel Pineapple Peel (Ananas comosus L.) Extract on the Growth of Propionibacterium acnes Latu, Saparuddin; Firman, Imran; Yaqkin-P, Andi Muh.; Musliani, Musliani
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.286

Abstract

Pineapple peel contains many compounds, namely flavonoids, tannins, saponins, phenolics, steroids, alkaloids and bromelin enzymes. Acne is a chronic inflammatory disease of the pilosebaceous glands. One of the bacteria that causes acne is Propionibacterium acne. Preparations that can be made for anti-acne are gel preparations. This study aims to determine whether the ethanol extract of pineapple peel (Ananas comosus L.) can be made into an anti-acne gel preparation and to find out at what concentration the ethanol extract of pineapple peel (Ananas comosus L.) in an anti-acne gel preparation can provide inhibitory activity on the development of Propionibacterium acne bacteria. This research method is true experimental by making anti-acne gel preparations of pineapple peel extract (Ananas Comosus L.) with various concentrations of 2%, 3%, 5% and testing the activity of the preparation against Propionibacterium acne using the agar well method. The results of the gel preparation formula showed that there were significant differences before and after the cycling test in both organoleptic, homogeneity, pH, viscosity, spreadability and adhesion tests. The activity test results obtained were that the largest inhibition zone was the 5% concentration, namely 12.7 mm, which was in the strong category, while the 3% concentration, which was 11.03 mm, and the 2% concentration, which was 8.8 mm, was included in the moderate category.
UV-Protection Activities of Labu Siam (Sechium edule) Extract Based on Sun Protection Factor (SPF) Anggraeni, Bella; Aminah, Aminah; Fawwaz, Muammar
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.287

Abstract

Exposure to sunlight has a negative effect on the skin. Sunscreens are used to protect the skin from the harmful effects caused by UV radiation. The ability of a sunscreen to protect the skin by delaying erythema is expressed by the value of the Sun Protection Factor (SPF). The purpose of this study was to analyze the UV protection activity of chayote (Sechium edule) based on the Sun Protection Factor (SPF) value, which was measured using UV-Vis spectrophotometry and calculated using the Mansyur equation. Based on the results of the study, it can be concluded that the SPF value of chayote (Sechium edule) extract has UV protection activity. At concentrations of 1%, 2%, and 3% there is activity as UV protection with SPF values of 7.487; 11.817; and 16,889. From the results obtained, it can be seen that the higher the concentration, the greater the SPF value obtained.UV-Protection Activities of Labu Siam (Sechium edule) Extract Based on Sun Protection Factor (SPF)
Antioxidant Activity Test of Ethyl Acetate Extract of Avocado Seeds (Persea americana Mill.) Using the 1,1-Diphenyl-2-Picrylhdrazyl Method Rahmat, Sri Rahayu; Pratama, Mamat
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.288

Abstract

Avocado is a plant that can thrive in tropical areas such as Indonesia and is one of the types of fruit that is popular with the public, however, avocado seeds have not been used optimally so that they are wasted as waste. Based on phytochemical experiments, avocados also contain phenolics, tannins and flavanoids which have antioxidant activity. Antioxidants are compounds that can be used to counteract free radicals. Dietary fiber and antioxidants are two types of components that are very useful in improving health and being able to prevent various diseases. The extraction method used in this study is reflux where the sample is heated for 6 hours with the solvent used to evaporate at high temperatures, but it will be cooled by the condenser so that the solvent which was in the form of vapor will condense in the condenser and fall again into the reaction vessel so that the solvent will still be there during the reaction. This study aims to analyze the antioxidant activity of the ethyl acetate extract of avocado seeds using the DPPH method. Quantitatively, the ethyl acetate extract of avocado seeds (Persea americana Mill.) was measured at a maximum wavelength of 516 nm using quercetin as a reference standard. The research results showed that the value was 903.08 μ/mL. Quantitatively, the ethyl acetate extract of avocado seeds (Persea americana Mill.) was measured at a maximum wavelength of 516 nm using quercetin as a reference standard. The research results showed that the value was 903.08 μ/mL. Quantitatively, the ethyl acetate extract of avocado seeds (Persea americana Mill.) was measured at a maximum wavelength of 516 nm using quercetin as a reference standard. The research results showed that the value was 903.08 μ/mL.
Antioxidant Activity of Ethanol Extract on Qust Al Hindi (Saussurea lappa) Roots Using the FRAP Method Putry, Dhevy Try; Syarif, Sukmawati; Rahmawati, Rahmawati
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.289

Abstract

Qust al hindi (Saussurea lappa) is a plant that has antioxidant activity, especially in the roots. Qust al hindi contains several chemical compounds including flavonoids, steroids, terpenes, alkaloids, sesquiterpenes, costunolide, dehydrococtus lactones, cynaropicrin, and chlorogenic acid. This study aims to determine the antioxidant activity of the ethanol extract of qust al hindi root using the FRAP method. Samples that had become powder were extracted using the soxhletation method with 96% ethanol and obtained a % rendition of 5.302%. The extract obtained was measured using a UV-Vis spectrophotometer at a maximum wavelength of 718 nm after being mixed with several FRAP reagents, using a quercetin standard. The results of the antioxidant analysis showed that the average antioxidant activity of the ethanol extract of the qust al hindi root (Saussurea lappa) using the Frap method was 10.3671 mgQE/g extract. Which means that the antioxidant activity of each g of extract is equivalent to the antioxidant activity of 10.3671 mg of quercetin.
Modulation Imaging Contrast Agent for Cancer Fawwaz, Muammar
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.283

Abstract

Molecular imaging, also known as molecular imaging, is a medical technique used to visualize and analyze biological molecules in the human or animal body. According to the Society of Nuclear Medicine and Molecular Imaging's website, "Molecular Imaging" is a type of medical imaging that provides a detailed picture of what is happening in the body at the molecular and cellular levels. This definition refers to the significant advancements researchers have made over the past two decades in applying the principles of molecular imaging in various areas, from basic and translational science to advanced patient diagnosis and therapy. Essentially, molecular imaging allows us to visualize biochemical processes and target localization patterns that are invisible at the level of anatomical imaging. The goal of molecular imaging is to obtain information about molecular activity and function in living tissue. The technologies commonly used in imaging modulation are Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Magnetic Resonance Imaging (MRI).

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