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Urecol Journal. Part C: Health Sciences
Published by Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
ISSN : -     EISSN : 27971791     DOI : -
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Urecol Journal. Part C: Health Sciences is a peer-reviewed journal published by Konsorsium LPPM Perguruan Tinggi Muhammadiyah Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY. This scientific journal specifically discusses the findings, new methods, and research experiences in health sciences from the University Research Colloquium (URECOL) which is held twice a year.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 6 Documents
 1 
Search results for , issue "Vol. 2 No. 2 (2022): August-Dec" : 6 Documents clear
Characterization and Modification of Corn Starch (Zea mays [L.]) and HPMC with Sodium Tripolyphosphate as Crosslinking Agent Muhammad Abdillah; Suprapto
Urecol Journal. Part C: Health Sciences Vol. 2 No. 2 (2022): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.170

Abstract

Corn starch is one type of starch that has the potential to be developed as an excipient in the manufacture of pharmaceutical preparations. However, this corn starch still has shortcomings in its flowability and compactibility. Based on this, corn starch needs to be modified physically and chemically by using the crosslinking method, namely changing the hydroxy group (OH-) with a phosphate group with sodium tripolyphosphate as the crosslink agent and HPMC as the polymer. The purpose of this study was to determine the physical and chemical characterization in the modification of corn starch-HPMC to various concentrations of sodium tripolyphosphate as a crosslinking agent. This study made 4 formulas with HPMC 10% and various concentrations of STPP (without treatment, 0.5%, 1%, and 2%). The modified starch will be characterized including FTIR test, SEM, swelling test, flow properties, and angle of repose. The results obtained in the FTIR test that the crosslink formed was at a concentration of 1% and 2% STPP which was indicated by the presence of an absorption band of the P-O-C group in the 1018cm-1 wave. The SEM test results showed that the addition of HPMC and STPP affected the physical form of starch with a rough and tight surface. In the swelling test, the modified starch increased with increasing STPP. In the flow properties test and the angle of repose, the modified starch has good flow properties and meets the requirements for a good angle of repose.
The Role of Public Health Workers in Facing the Challenges of Health Development Post-Covid-19 Pandemic: A Review Nona Carolina; Chalda Bhakti Jelika; Ivani Kartika Cahyani Putri; Anjani Betty Afriani; Trinita Agustia Lasmana
Urecol Journal. Part C: Health Sciences Vol. 2 No. 2 (2022): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.171

Abstract

The Covid-19 pandemic is an outbreak of an infectious disease caused by the SARS-CoV-2 virus. This virus can be easily transmitted through direct contact with infected people or by touching objects that have been contaminated. This virus has spread in various countries, one of which is Indonesia. With the spread of this virus, health development in Indonesia is critical. Therefore, to face the challenges of health development after the Covid-19 pandemic, the role of public health workers is very necessary. This study uses a literature review method by collecting data from various journals that discuss the role of public health. This study produced several findings related to the role of public health workers in facing the challenges of health development after the Covid-19 pandemic. These roles include health promotion, environmental health, occupational health and safety, and health care systems.
The Easiness in silico Drug Development against SARS-CoV-2 Protease using JAMDA Broto Santoso; Ratna Yuliani
Urecol Journal. Part C: Health Sciences Vol. 2 No. 2 (2022): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.172

Abstract

Drug development can be accelerated and facilitated through the method of in silico by utilising a browser-based application. Universität Hamburg through the ZBH Centre for Bioinformatics has been giving full access to its applications until now. One of them is JAMDA. Forty-five flavonoids have been used as case studies of ligand binding affinity screening for five SARS-CoV-2 proteases. The 3D conformations of ligands and proteins were downloaded from the PubChem and RCSB databases, respectively. OpenBabel was used to combine multiple ligands to speed up the computation. It took at least 7.5 hours to complete the whole process using a single browser tab. Molecules of GC376 non-sulphonate, R8H, and 6”-O-acetylastragalin have top best scores than all investigated ligands. Their average scores ratio is 1.239, 1.234 and 1.188 respectively. PLIP predictions indicate that water molecules are actively involved in protein ligand interactions for four crystals of native and 6”-O-acetylstragalin on several proteins. This browser-based application is fast and easy to use but it is not recommended to use for novel compounds due to data privacy which is not guaranteed by the owner.
Optimation of Red Ginger (Zingiberofficinale Roxb) Extract Lozenges with Various Concentrations of Binding and Disintegrant Materials Dwi Bagus Pambudi; St. Rahmatullah; Novel Umarella; Hilda Fitria Wulandari; Dewi Safitri
Urecol Journal. Part C: Health Sciences Vol. 2 No. 2 (2022): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.173

Abstract

The red ginger plant through several studies is known to have potential as a medicinal plant because it contains oleoresin and flavonoid that can relieve symptoms of coughs and are also effective in curing symptoms of sore throat, especially sore throat. The use of medicinal plants are active ingredients in herbal medicinal preparations has been widely used, especially in tablet preparations. In this study, tablets were formulated in 3 formulations with varying concentrations of binder and disintegrant. The method used in the wet granulation’s method because the selection of the method is adjusted to the nature of the extract and excipients to be used. Based on the tablet evaluation results, it was shown that the 3 formulas only met the requirements for the size uniformity test and the disintegration time test.
Interferon-? Expression in Histopathological specimens with Invasive Breast Carcinoma of No Special Type at Menopause and Reproductive age Yuni Prastyo Kurniati; Syafira Anggraini Khusna; Elisna Dwi Anggraeni
Urecol Journal. Part C: Health Sciences Vol. 2 No. 2 (2022): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.174

Abstract

Invasive breast carcinoma of No special type is the most common type of breast cancer with a prevalence of 50% to 80%. Breast cancer is an important threat in women of menopausal age, and only 5-7% are diagnosed under the age of 40 years. The most common risk factor for cancer is immune system disorders. There is a decrease sex hormone during menopause that results disruption of the body's immune system in the elderly. Women of reproductive age have elevated levels of T CD4+ and immunoglobulins in the circulation. Naïve CD4+ cells produce more IFN-?. IFN-? is a cytokine at innate and adaptive immunity that has proven important in antitumor immune response. Purpose: This study proves IFN-? expression in NST histopathology based on reproductive and menopause age. Method: Research is observational analytic with a cross sectional approach. NST parafin blocks specimens as many as 16 samples from the menopause age and 15 samples from the reproductive age. Then, the painting and examination of Immunohistochemistry IFN-?. Results: Fisher tests get a value of p = 0.5 at the age of menopause and the Mann Whitney test with a value of p = 0.823 at reproductive age. Conclusion: There is no association between menopausal age and reproductive age with IFN-? expression in the histopathology specimen of Invasive breast carcinoma of No special type patients. However, there was an increase in IFN-? expression in the specimen of reproductive age by 60%.
Nurse Workload Against Burnout Syndrome in the Emergency Room Endah Setianingsih; Nur Wiji Lestari; Barkah Waladani
Urecol Journal. Part C: Health Sciences Vol. 2 No. 2 (2022): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.200

Abstract

The Emergency Room is a first aid unit to save lives and prevent death. The high number of visits and the unpredictable condition of patients in the emergency department is one of the stressors. Emergency room nurses have a high risk of fatigue due to work demands and workloads that cause fatigue and boredom. The workload received by nurses is closely related to the level of burnout syndrome. To determine the relationship between workload and burnout syndrome of nurses in the Emergency Room. This study is a quantitative study. The research population was nurses in the emergency room at PKU Muhammadiyah Gombong Hospital. The number of samples used were 27 nurses. Nurses with a heavy workload were 78%, while those with severe burnout were 48%. From the results of the Chi Square test, it was found that the P value of 0.020 workload with burnout syndrome had a significant relationship. There is a significant relationship between workload and burnout syndrome of nurses in the Emergency Room.

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