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Murdani Abdullah
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Divisi Gastroenterologi, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN Dr. Cipto Mangunkusumo, Jl. Diponegoro No. 71 Jakarta 10430 Indonesia
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INDONESIA
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Published by The Indonesian Society for Digestive Endoscopy
ISSN : 14114801     EISSN : 23028181     DOI : -
Core Subject : Health,
Medicine & Pharmacology
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive Endoscopy. The aim of our journal is to advance knowledge in Gastroenterology, Hepatology, and Digestive Endoscopy fields. We welcome authors for original articles, review articles, and case reports in the fields of Gastroenterology, Hepatology, and Digestive Endoscopy.
Arjuna Subject : Kedokteran - Ilmu Pencernaan
Articles 7 Documents
 1 
Search results for , issue "VOLUME 7, ISSUE 3, December 2006" : 7 Documents clear
Clinical Improvement of Dyspepsia Symptoms Following Eradication Treatment for Helicobacter pylori Khaira Utia Yusrie; Ari Fahrial Syam
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 3, December 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/73200672-78

Abstract

The prevalence of Helicobacter pylori in patients with peptic ulcer in Indonesia is very high. It ranges between 90-100%. In general, patients with gastritis and peptic ulcer usually have dyspepsia symptoms. The pathophysiology of dyspepsia symptoms caused by Helicobacter pylori has not been clearly understood. However, it is assumed that the symptoms are correlated to various factors including inflammation, apoptosis damage, and increased secretion of gastric acid, atrophy and non-atrophy gastritis as well as the development of peptic ulcer. The main objective of treatment for Helicobacter pylori infection is elimination of Helicobacter pylori bacteria. Triple therapy has 80% success rate with no significant adverse events and minimal effect in inducing resistance to antibiotics. The success rate of eradication treatment in patients with peptic ulcer is 90%; while an evaluation on improvement of duodenal ulcus following eradication treatment with one month proton pump inhibitor treatment reveals 90% success rate. Keywords: Helicobacter pylori, improvement, dispepsia
Portal Hypertensive Enteropathy in Liver Cirrhosis Marcellus Simadibrata; Vera Yuwono; FJW Ten Kate; GNJ Tytgat; Daldiyono Daldiyono; Laurentius Lesmana; Iwan Ariawan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 3, December 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/73200661-66

Abstract

Background/Aim: Some studies found that portal hypertension cause complication such as portal hypertensive gastroenterocolopathy. This study was done to find any abnormalities in the small intestinal mucosa and villi of the portal hypertensive patients. Method: Thirty patients with liver cirrhosis, portal hypertension and esophageal varices between 2000 - 2001 were included in this study. A duodenoscopic examination was performed to determine any abnormalities. Biopsy specimens were taken from the descending part of duodenum and the duodenal bulb for histopathological examination. The findings were compared to 37 functional dyspepsia patients. Result: In the duodenal bulb and descending part of duodenum: the width of the villous of the portal hypertensive group was larger than the control (p 0.001), the diameter of the mucosal villous vessel was larger than in the control (p 0.001) and the thickness of the mucosal villous vessel wall was thicker than in the control (p 0.001). Conclusion: There were abnormalities of the mucosa in portal hypertensive enteropathy patients including the mucosal vessel diameter, wall thickness, number of goblet cells. Keywords: portal hypertensive enteropathy, liver cirrhosis
Serum Biochemical Markers of Liver Fibrosis Irwan Setiabudi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 3, December 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/73200679-81

Abstract

Progressive liver fibrosis with development of cirrhosis is a feature of almost all chronic liver diseases. Carriers of hepatitis B and C virus are at increased risk of developing cirrhosis, hepatic decompensation/insufficiency, hemorrhage, and hepatocellular carcinoma (HCC). Therefore, periodic evaluations of these patients are necessary. Fibrosis is deleterious but variable consequence of chronic inflammation. It is characterized by deposition of extra cellular matrix component leading to distortion of hepatic architecture with impairment of liver microcirculation and liver cell function. Although liver biopsy is the gold standard for assessment of liver fibrosis, it has several disadvantages. Considering these limitations and patient redundancy to undergo liver biopsy, it is vital that non -invasive predictors/ Methods for assessment of liver fibrosis be developed and validated. Application of this Method could be used to evaluate the efficacy of treatment, which is a simple and meaningful way. Recently, clinical investigators have been searching for noninvasive serum markers of fibrosis, which have the following characteristics: they must be reliable, accurate, reproducible and easy to perform. Several markers or combination of several markers have shown promise for the detection of advanced fibrosis, although their sensitivities for detecting milder fibrosis are poor. Non -invasive laboratory bio-markers of liver fibrosis might be applied to patients who either have contra-indication or refuse liver biopsy for management of their chronic liver diseases. Keywords: hepatitis B virus, liver fibrosis, liver biopsy
Endoscopic Features of Patients with Bronchial Asthma and Gastroesophageal Reflux Symptoms Syafruddin AR Lelosutan; Agus Dwi Susanto; Ruswhandi M
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 3, December 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/73200667-71

Abstract

Background: Studies evaluating endoscopic results in patients with bronchial asthma and Gastroesophageal Reflux Disease (GERD) in Gatot Soebroto hospital have never been undertaken. It leads an idea to further study, in order to find a more accurate and rapid management as solution for anticipating asthma attack and complications of bronchial asthma to upper gastrointestinal tract. Methods: A retrospective study was aimed to evaluate endoscopic result of upper gastrointestinal tract in bronchial asthma patients who had GERD symptoms as appropriate to the criteria of 4 major GERD symptoms of Talley 2002. Data was collected in one year period starting from November 2004 to October 2005. Results: Subject characteristics in this study indicated that there were more female patients compared to male with a ratio approaching 3:1 who had such symptoms. Mean age was 38.5 years and ratio of body weight to body height indicated normal weight result and the mean value for duration of asthma was 27 years. Clinical symptoms of GERD found in the present study was in accordance with four majors symptoms of GERD i.e. 32 (100.00%) cases of regurgitation, 29 (90.63%) cases for each of heartburn and non-cardiac chest pain symptom, and 7 (21.88%) cases of difficult / painful swallowing or dys/odinophagia. The endoscopic result of upper gastrointestinal tract had figured of: (1) 4 (12.50%) cases of normal esophagus, (2) 11 (34.40%) cases of non-erosive esophagitis known as Non Erosive Reflux Disease (NERD), and (3) erosive esophagitis which regarding to Los Angeles classification: 15 (46.90%) cases of grade A and 2 (6.20%) cases of grade B. Conclusion: The incidence of esophagitis in accordance with LA classification is extremely high although no severe damage (grade C and grade D) was found. Early anticipation of reflux associated respiratory symptoms and anti-reflux treatment should be considered in order to shorten or to discontinue the asthma attack cycle. Keywords: bronchial asthma, GERD, endoscopy, NERD
Peutz Jeghers Syndrome M Purnomo Isnaeni; Marcellus Simadibrata; Murdani Abdullah; Ari Fahrial Syam; Achmad Fauzi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 3, December 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/73200682-85

Abstract

Peutz-Jeghers Syndrome (PJS) is a rare condition that tends to run in families. Diagnosis of PJS is made if a person has polyps in the gastrointestinal (GI) tract and at least two of the following: polyps in the small bowel, melanin spots, and/or a family history of PJS. The typical clinical manifestation of the disease is associated with complications secondary to intestinal polyps often requiring surgical treatment. A young woman, 29 years old with PJS had been hospitalized in Cipto Mangunkusumo hospital. She was suffering from GI complication secondary to her polyps such as abdominal pain, nausea, vomited every time she takes her meal and milk, anorexia, fatigue, weakness, chronic diarrhea with hematoschezia. Upper and lower endoscopy showed the multiple polyps along from esophagus, gaster, duodenum, and her colon. Histopathology examination confirmed the type of polyps is Peutz Jeghers with the unique morphology consisting of mucosa with interdigitating smooth muscle bundles that yield a characteristic branching tree appearance. We also found the family tree of this patient and it is a good evident how PJS can be inherited in a family. Keywords: Peutz-Jeghers syndrome, melanin spots, polypsry
Gastric Amyloidosis Achmad Fauzi; Fajar Raditya; Ari Fahrial Syam; Abdul Aziz Rani
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 3, December 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/73200686-89

Abstract

Amyloidosis occurs as secondary to rheumatoid arthritis, inflammatory bowel disease and other diseases and also associated with familial Mediterranean fever. Outcomes are worse if there are cardiac or gastrointestinal manifestations. A 57 year-old female was admitted to our hospital with clinical manifestations of nausea, vomiting, epigastric pain, odynophagia, dysphagia and chronic diarrhea. She has also history of rheumatoid arthritis for 10 years. Upper gastrointestinal endoscopy revealed hyperemia in the whole region of gastric mucosa and lower gastrointestinal endoscopy showed hyperemia with erosion in colonic and ileal mucosa. Histopathologic examination of the gastric biopsy showed the deposition of amyloid materials in the mucosa. We report a case of gastric amyloidosis secondary to rheumatoid arthritis. Keywords: gastric amyloidosis, rheumatoid arthritis, dyspepsia
The Prevalence of Hepatitis B Virus in Female Commercial Sex Workers Bradley Jimmy Waleleng; J Kairupan; Nelly Tendean Wenas
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 3, December 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/73200657-60

Abstract

Background: The prevalence of hepatitis B infection in Indonesia was about 2-20%. To date, incidence rate of Hepatitis B Virus (HBV) in female Commercial Sex Workers (CSW) in Manado was not known. Objective: To investigate the prevalence and risk factors associated with HBV in female CSW. Methods: This is a descriptive-analytic study with cross-sectional design. Target population was female CSW in Manado. Results: Of 177 subjects, age range 15-49 years (27.87 ± 7.629), the most frequent age were 20-24 years with 56 subjects (31.6%). Serum HBsAg was positive in 8 (4.5%) subjects. Serum HBsAg was positive in 8 of 143 (5.6%) subjects with intercourse frequency 5 times weekly, 8 of 142 (5.6%) subjects with sexual partner 5 per week, 1 of 41 (2.4%) subject worked as CSW 1 year, 7 of 136 (5.1%) subjects worked as CSW for more than a year, and 1 of 110 (0.9%) subjects who used condom. Conclusion: Prevalence rate of hepatitis B in female CSW in Manado was 4.5%. There was significant relationship between condom usage and the prevalence of hepatitis B virus infection. There was relationship with some other risk factors but statistically insignificant. Keywords: hepatitis B virus, prevalence, commercial sex worker, condom usage

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