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Nailis Syifa
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Farmasains : Jurnal Farmasi dan Ilmu Kesehatan
Published by Universitas Muhammadiyah Malang
ISSN : 20863373     EISSN : 2620987X     DOI : 10.22219
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Farmasains publishes articles that cover textual and fieldwork studies with various perspectives of pharmacy science including: Pharmaceutical Technology Pharmaceutical Chemistry Biology Pharmacy and Natural Products Pharmacology and Toxicology Clinical Pharmacy Community Pharmacy Pharmacoepidemiology Pharmacogenomic and Pharmacogenetic Pharmacoeconomic Health-related topics
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
 1 
Search results for , issue "Vol. 6 No. 2 (2021)" : 6 Documents clear
Analysis precision of joint pain in Apotek Kimia Farma Mejasem Tegal Shellma Noor Aida; Heru Nurcahyo; Joko Santoso
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 6 No. 2 (2021)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v6i2.15957

Abstract

This research aims to find out and analyze the accuracy of self-medication for joint pain in the community, especially those who buy drugs at the Apotek Kimia Farma, Mejasem, Tegal. The sampling technique in this study uses the purposive sampling method, which determines sampling by determining specific characteristics according to the research objectives so that it is expected to answer the research problem. This research is classified into descriptive research, namely research with a method to make a systematic description of the accuracy of self-medication for joint pain in the community who visited the Apotek Kimia Farma Mejasem. The instruments used in this study were demographic data and questionnaires. The work steps used in data collection in this study used interview techniques guided by the questionnaire. The results of the study were as follows, community self-medication in joint pain showed the correct percentage of people with an indication of 85%, the percentage of people who were right in the group of 85%, the percentage of people who had the correct dose of 71%, and the percentage of people who were alert to drug side effects was 27%. In conclusion, most people who buy drugs at the Apotek Kimia Farma Mejasem were correct in self-medication for joint pain, except for the awareness of drug side effects. The percentage of people who had the correct dose was 71%, and the percentage of people alert to drug side effects was 27%.
A method validation and analysis of lead content in lipstick products sold in e-commerce using atomic absorption spectrophotometer (AAS) Dian Prasasti; Divanda Liling Sasanti
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 6 No. 2 (2021)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v6i2.17250

Abstract

Lipstick is the most widely cosmetic that used to beautify the appearance of the face. Lipstick that safe to use has an amount of lead metal less than 20 ppm. This study aims to ensure that the analytical method used has been validated, to determine the metal content of lead in lipsticks that sold in e-commerce, to determine the average metal content of lead using an Atomic Absorption Spectrophotometer (AAS) and to determine the safety of the lipstick. The methods used to validation are determine linearity, accuracy, precision, LoD, and LoQ. Samples were obtained from e-commerce with criteria that had price less than IDR 17,500, had sales history at least 10,000 units and had shipments from within the country. Sample preparation was carried out by wet digestion method, then analyzed qualitatively by tube test and analyzed quantitatively by measuring its absorption using AAS. The results obtained from this study are the linearity of validation parameter is 0.9959, the percent accuracy is entirely in the range 80-110%, the percent precision is less than 11% and the LoD and LoQ numbers are 0.630 ppm and 1.908 ppm. The average levels of lead contained in lipsticks that sold in e-commerce for brands A to F are 33.285±0.918 ppm; 33.576±0.918 ppm; 35.029±0.918 ppm; 38.372±1.836 ppm; 39.390±0.918 ppm; and 32.994±0.918 ppm. Lipstick brands A, B, C, D, E, and F contain more than 20 ppm lead metal so they are not safe for daily use.
Cost-effectiveness analysis of cefazolin and clindamycin in postpartum patients at PKU Muhammadiyah Hospital Yogyakarta Anggita Esa Putri Fitrichia; Susan Fitria Candradewi; Dewi Inggit Karnasi; Adnan Adnan
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 6 No. 2 (2021)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v6i2.17289

Abstract

Postpartum infections can occur after normal or cesarean delivery. Proper administration of antibiotics can reduce the risk of postpartum infection The occurrence of postpartum infections can increase the cost of childbirth. The purpose of this study is to find out the cost-effectiveness of antibiotic therapy at PKU Muhammadiyah Hospital Yogyakarta.  This study was retrospective observational and was conducted during October to December 2020. The inclusion criteria in this study were postpartum patients who received cefazolin and clindamycin therapy and were over 20 years old, while the exclusion criteria in this study were patients who died, had incomplete data, and had complications of the disease. The effectiveness of antibiotic therapy was measured from the clinical outside of body temperature and length of hospitalization. Cost-effectiveness were assessed from ACER (Average Cost-effectiveness Ratio) and ICER (Incremental Cost-effectiveness Ratio). The results showed that the effectiveness of antibiotics based on the clinical outcome temperature and length of  cefazolin of 81.3% and 2.7 days while in clindamycin by 18.8% and 1.8 days. The ACER (Average cost effectiveness ratio) based on the clinical output of body temperature in both groups was IDR 64,348 (cefazolin) and IDR 98,319 (clindamycin). ACER values based on long of stay (LOS) clinical discharge in both groups amounted to IDR 19,375 (cefazolin) and IDR 10,268 (clindamycin). The value of ICER (Incremental Cost- effectiveness Ratio) cefazolin against clindamycin based on the clinical output of temperature and length of hospitalization (LOS) respectively is IDR 54,129 and IDR 37,590 for each effectiveness achieved. The conclusion of this study is that the use of cefeazoline is more therapeutically effective than clindamycin with greater therapeutic costs.
Comparison of physical properties and effectiveness of facial wash gel nipah shell (Nypa fruticans Wurmb.) activated charcoal with palm shell (Elaeis guineensis Jacq.) activated charcoal as a facial cleanser Uce Lestari; Eugenia Griselta; Muhaimin Muhaimin
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 6 No. 2 (2021)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v6i2.17328

Abstract

Activated charcoal is an amorphous carbon that has a high absorption capacity and can be made using plantation waste such as nipah shell and palm shell. Activated charcoal from nipah shell and palm shell have high absorption when used to absorb dirt and oil on the face by being formulated as a facial wash in the form of a gel. This study was conducted to compare the physical properties and effectiveness of facial wash gel with activated charcoal nipah shell and activated charcoal palm shell with a concentration of 4% of each activated charcoal and determine which facial wash gel has better physical properties and effectiveness than the control positive namely Biore Men Charcoal. The physical properties tested included: organoleptic observation, homogeneity, spreadability, pH, foaming ability, cycling test, irritation test, moisture and oil test using a skin analyzer and dirt absorption effectiveness test using a digital microscope. The results showed that facial wash gel activated charcoal palm shell had physical properties closer to control (+) and better effectiveness, with an average oil reduction percentage of 17% compared to facial wash gel activated charcoal nipah shell, which was 15%. From these results, it can be concluded that facial wash gel activated charcoal palm shell has better physical properties and is more effective in cleaning oil and dirt on the face compared to facial wash gel activated charcoal nipah shell.
Bioactive Compounds Content and Pharmacological Activities of Chili Pepper (Capsicum Sp.) Swastiari Dwi Yanti; Warsi Warsi
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 6 No. 2 (2021)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v6i2.17401

Abstract

Chili pepper (Capsicum sp.) is an essential spice belonging to the Solanaceae family. Chili pepper is consumed as a food source, additive in the food industry, and necessary medicine. Chili pepper is rich in nutrients and secondary metabolites to generate new bioactive compounds. Chili pepper fruit contains bioactive compounds including alkaloids, capsaicinoid, carotenoids (anteraxanthin, β-carotene, capsanthin, violaxanthin, β-cryptoxanthin, zeaxanthin, lutein epoxide, capsorubin, and neoxanthin), peptides (defensin, thionin-like peptide), phytol, fatty acids (myristic acid, methyl stearic, methyl linoleic), phenolic (chlorogenic acid) and flavonoids (quercetin, luteolin, rutin). The compounds in chili pepper constitute a bioactive source that acts as an antioxidant, antimicrobial, antifungal, anti-inflammatory, anti-obesity, anti-diabetic, and dyslipidemia. This review intends to describe the content of bioactive compounds that are very beneficial for health. This review is expected to increase chili consumption and its application in the food industry
Comparison of Antioxidant Activities of Ethyl Acetate Extracts of Two Varieties of Sweet Potato Tuber [Ipomoea Batatas (L.)] Using Two Extraction Methodsomoea batatas (L.)] MENGGUNAKAN DUA METODE EKSTRAKSI Hendy Suhendy; Defri Risviana; Imas Ratnasari
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 6 No. 2 (2021)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v6i2.18069

Abstract

The decrease in antioxidant activity can be caused by the destruction of antioxidant compounds due to heating. Several studies stated that there was no significant difference between the antioxidant activity of extracts from cold extraction and hot extraction. This study compares the antioxidant activity of the ethyl acetate extract of two varieties of sweet potato using two different extraction methods. Simplicia was extracted by hot extraction using reflux and cold extraction using maceration. The antioxidant activity of the extracts was tested by the DPPH method using UV-Vis spectrophotometry. There are two types of sweet potato used in this research; firstly, the outer skin of the tuber is purple, the inside is purple (UU), and, secondly, the outer skin is purple, the inside is orange (UO). The IC50 UUR (Purple-Purple Refluxed), UOR (Purple-Orange Refluxed), UUM (Purple-Purple Macerated), UOM (Purple-Orange Macerated) , and ascorbic acid values were 4.583, 4.614, 0.755, 18.142, and 2.680 g/ml; thus, the extraction method and sweet potato varieties affect the antioxidant activity of the extract. Maceration is the best method for UU, while reflux is the best method for UO.

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