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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 1,092 Documents
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Strategies, Management of Urban Transport and its Solutions, with Sustainable Development Approach (Case Study: Tehran) Maryam Esmaeili
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

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Abstract

Sustainable transport concepts that are always changing the type of fuel and reduce fuel consumption car or use public transportation to the mind.In the meantime, pay attention to issues relating to sustainable development can be explained by causes instability and factors affecting transport in cities with a sustainable approach examined.In addition, it can transport needs and requirements to achieve sustainable urban design and planning presented. But in the meantime, variables such as dimensions of sustainable development and its axis can specify various aspects of this process.Therefore, the aim of the present study provide urban transport management strategies and solutions with a sustainable development approach, the analytical method.To achieve this goal, first to experience the world of transportation was different cities of the world, then transport axes Paydarmvrd was investigated. As well as transport and traffic studies Tehran was assessed, finally, urban transport planning and management strategies and solutions that were presented.The results show that most interest is the urban management policies, teaching and development of traffic culture as the main solution to the traffic problem in Tehran, which will help to urban planning.Keywords: Urban transportation, Transportation management, Sustainable development, Tehran city.
Knowledge on Cervical Cancer Prevention and Attitude towards Pap smear and HPV Vaccination among Women Attending a Health Clinic in IPOH, Malaysia Sandheep Sugathan
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

Objectives: Cervical cancer is the second most common cancer among women in Malaysia and is one of the leading causes of cancer mortality in women worldwide. This study was carried out to study the knowledge level regarding cervical cancer prevention and attitude towards Pap smear and HPV vaccination among women attending Greentown outpatient clinic in Ipoh, Malaysia. Methods: Data were collected using a structured questionnaire which included socio-demographic characteristics, knowledge of cervical cancer, Pap smear and HPV vaccination and attitude towards Pap smear and HPV vaccination from a sample of 100 women of age between 16 and 65 years, who were attending the Greentown outpatient clinic in Ipoh, Perak from 21st July to 8th August 2014.Results: Most of the participants were of the age group of 26 to 45 years (44%). Majority of the respondents had good knowledge of cervical cancer, Pap smear and HPV vaccination and showed good attitude towards Pap smear and HPV vaccination. Knowledge levels were significantly different in the different age groups. Attitude on Pap smear and HPV vaccination was significantly higher among higher education groups and employed groups. Conclusion: Age was significantly associated with knowledge levels on cervical cancer prevention and HPV vaccination. Education and occupation levels were significantly influencing the attitude of women regarding cervical cancer, Pap smear and HPV vaccination.
Simultaneous Determination of Furosemide, Carbamazepine, Diazepam and Carvedilol in Quaternary Mixture via Derivative Spectrophotometry Nahla. A. Alassaf
Journal of Global Pharma Technology Volume 11 Issue 05.
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Abstract

Quick and accurate quaternary mixture resolution of furosemide (FURO), carbamazepine (CARB), diazepam (DIAZ) and carvedilol (CARV) by using derivative spectrophotometric method was performed. FURO and CARV were determined by means of first (D1), second (D2), third (D3) and fourth (D4) derivative spectrophotometric methods,  CARB was determined by using D1, D2, D3 derivatives, while D1 and D2 were used for the determination of DIAZ. The recommended methods were verified using laboratory prepared mixtures and then successfully applied for the pharmaceutical formulations analysis of the cited drugs. The results obtained revealed the efficiency of the proposed methods as quantitative tool of analysis of the quaternary mixture with no requirements for sample neither pretreatment nor preliminary separation of analytes from the pharmaceutical preparations.Keywords: Derivative spectrophotometry; Furosemide; Carbamazepine; Diazepam; Carvedilol.
Chemistry in Forensics and Crime Solving: Review Dina B. Abbas AL-Saedi
Journal of Global Pharma Technology .
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Abstract

Chemistry is one of the most important forensic sciences beside of the other evidence sciences, and it is focus on the chemical examination of chemical waste by different methods of analytical chemistry and instrumental analytical methods. In addition to the quantitative and qualitative analyzes, it is possible to perform a comparative and comparison between the different samples and the connection between them in different fields associated with crimes. Forensic chemistry includes organic and inorganic analysis, toxicology, arson investigation, and serology. Each method of analysis uses specialized techniques and instrumentation. The process may be as simple as setting up a density gradient column to compare soil samples or as complicated as using a mass spectrometer or neutron activation analysis to characterize an unknown substance.Keywords: Analytical chemistry, Forensic sciences, Toxicology, Finger print.
Several Parameters of Blanching and Drying Influencing to Quality of Dried Pumpkin Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 11 Issue 01.
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Abstract

Is one such plant that is frequently being used as food as well as traditional medicine for long days. It is a large climbing herb, annual or perennial, for use as vegetable as well as medicine. It contains several phytochemicals including alkaloids, flavanoids, phenols, carbohydrates, tannins, saponins, terpenoids and proteins.  The presence of these phytochemicals has been found to possess various medicinal functional functions which are essential in the management of various diverse ailments.  Pumpkin has gained a considerable attention in recent years for its nutritional and health promoting values. Drying is a relatively simple process in which water activity in food is reduced, minimizing or inhibiting the chemical and enzymatic reactions and microbial growth that are responsible for its deterioration. Therefore, objective of this study focused on the effect of blanching temperature and time; heat pump drying temperature and storage condition to β-caroten (mg/100), vitamin C (mg/100g), rehydration capacity (kg moisture/kg d.s.), sensory score of the dried pumpkin (Cucurbita spp.). Results showed that pumpkin (Cucurbita spp.) should be blanched in hot water 95oC at 10 seconds in the present of citric acid 4g/l and then beeing dried by heat pump dryer at 50oC until 12% moisture. Blanching is carried out to improve food quality by inactivating enzymes, reducing microorganisms and preserve the natural color when pumpkin after blanching is subjected to drying. The final dried pumpkin was shelf-stable for a period of 12 weeks at ambient temperature without any appreciable adverse changes in physico-chemical as well as sensory quality characteristics of the dried products.Keywords: Pumpkin, Blanching, Drying, β-caroten, Vitamin C, Rehydration capacity.
Synthesis Conditions of AgCore@Au Shell System by Laser Ablation with (1064, 532, 355) nm Wave lengths Ghaleb Al-Dahash
Journal of Global Pharma Technology .
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Laser ablation in liquid technique (PLA) has become a more important for the preparation of NPs. Metal targets were laser ablated in liquid for preparation of spherical Ag @ Au core @ shell NPS colloidal solution for refractive index sensing. In our research was prepared Core-shell Nano colloid system of Ag @ Au by using pulses of Nd-YAG laser with (1064, 532, 355) nm wavelength and (80 @ 60) mJ energy in ethanol liquid. The Surface texture, topography and morphology studied by Transmission Electron Microscopy (TEM) and Scanning Electron Microscope (SEM).Our structural analysis indicated the grains show spherical shape, where TEM images showed formation of Core-Shell clearly, UV-Visible spectroscopy has been employed for the optical properties measurements, Absorption peaks shifted to lower wavelength (blue shift) (UV). The effect of (Ag -core) was more effective than the (Ag - shell), and so by the sliver core effect (Ag -Core), and this confirms clear evidence that the effect of the (Core) influential, which dominates the effect of (shell).
Lack of Association between Hypercholesterolemia and Obesity Status with the Gallstones type among Cholelithiasis Patients at Sanglah General Hospital, Bali, Indonesia Heru Sutanto Koerniawan
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

Introduction: Gallstone disease is still one of the major health problems in the world. It is one of the most common diseases in developed countries associated with many factors. Increased total blood cholesterol, free cholesterol, LDL, triacylglycerol, obesity, and decreased HDL cholesterol levels also play an important role in the pathogenesis of gallstone formation. This study aimed to determine the relationship between hypercholesterolemia and obesity to types of gallstones. Methods: An observational cross-sectional study was conducted at Sanglah General Hospital from January-December 2017. The sample was obtained using consecutive sampling of patients with cholelithiasis that met inclusion and exclusion criteria. Data analysis was done with univariate and bivariate analysis using SPSS version 23 software. The confidence interval was set to 95% and p-value < 0.05 was considered statistically significant. Result: Twenty-six samples were included in this study. Majority of the sample was suffered from gall stone type cholesterol and was performed open cholecystectomy. There was no association found between gall stone type and obesity (p=0.618). In addition, recent findings also suggest no significant differences between gall stone type and total cholesterol status (p=0.211).Conclusion: There is no association between obesity and hypercholesterolemia with gall stone type in cholelithiasis patients.Keywords: Cholelithiasis, Gallstone, Hypercholesterolemia, Obesity.
Effect of Self Efficacy Training on Diet and Blood Glucose Compliance in Diabetes Type 2 Mellitus Patients Hariyono Hariyono
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Background: Self-efficacy training is an effective way for people with diabetes mellitus to get improved blood glucose compliance and control. The purpose of this study was to analyze the effect of self-efficacy training on diet compliance and blood glucose. Methods: This study used a quasi-experimental pre-post-test with a control group. The population of this study was all Diabetes Mellitus patients in the Public Health Center area with 17 sample respondents for each group. The sampling technique was purposive sampling. The variables of this study were: self-efficacy training, diet compliance, and blood glucose. The way to collect data was by using questionnaires and laboratory examinations. Result:  The results showed that self efficacy training did not affect the adherence of diabetic patients in either the intervention group or the control group with the Wilcoxon test results showing the intervention group (p = 0.863 (p <0.05)), the control group (p = 0.677 (p < 0.05)) and the Mann-Whitney test (p = 0.909 (p> 0.05)). The second result showed that self-efficacy training had an effect on blood glucose in patients with Diabetes Mellitus in the intervention group but did not affect the control group, according to the Wilcoxon test results showed for the intervention group (p = 0.003 (p <0.05), the control group (p = 0.163 (p> 0.05) and the Mann-Whitney test (p = 0.080 (p> 0.05). Discussion: self-efficacy training can improve blood glucose control quite well, but still requires integration with other components related to the pillars of Diabetes Mellitus management. Self-efficacy training is not significant enough to improve the adherence of diabetic patients but with increased knowledge and behavior, it is hoped that they will be able to increase their motivation to support increased self-care abilities, change behavior and carry out activities to maintain glycemic control.Keyword: Self Efficacy Training, Diet Compliance, Blood Glucose, Glycemic Control, Diabetes Mellitus.
Study of the Psychosocial Aspects of Epileptic Patient Attending the Middle Euphrates Neurological Sciences Center in AL-Najaf AL-Ashraf Province in Iraq Salma KJ
Journal of Global Pharma Technology .
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The findings of the present study indicated that the overall domains have an effect on patients with epilepsy among those domains social isolation which was the highest. Objectives: are to identify the demographic characteristics of the sample, also find out the impact of the epilepsy on patient psychosocial aspects, and Find out the relationship between the demographic characteristics of the patient and the impact of the epilepsy. Methodology: A descriptive Cross-sectional study was conducted on a non probability (purposive sampling) which consists of (100) patients with epilepsy who attending the Middle Euphrates Neurological Sciences Center in AL-Najaf AL-Ashraf Province, from September 16th 2016 to October 20th 2017.Results: The results of the study found that majority of participants are males and aged between (20-30) years old, most of them are married, high percentage of the sample was illiterate and regarding sample monthly income, it was found that patients were satisfied; age disease of onset found to be at (21-more) years old,  the majority them were non-smokers, the pathology of epilepsy is idiopathic more than symptomatic in clinical data. Finally there was no significant relationship between the overall patient’s psychosocial aspects and their clinical data also demographic data. Conclusion: The study concludes that social isolation is one of the psychosocial aspects that scored severs effect in many of the items, no significant relationship was found between the overall patient psychosocial aspects and the family and social support. Recommendations: Patients can be given more chances to share the health care providers with their experiences and all the issues related to the attack. It's better to provide the patients with an identification card clarifying some information about the particular patient.Keywords: Psychosocial aspects, Stigma, Epilepsy, Pathology of epilepsy.
Molecular Detection of Fungal Species in a Sample of Iraqi Patients with Meningitis Ahmed Sahib Abdulamir
Journal of Global Pharma Technology .
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Background: Infections of the central nervous system (CNS) with fungi can cause devastating consequences. Although, several fungi may result in infection of normal humans, most of them are opportunistic and influence immuno-compromised hosts. Invasion of the CNS with fungi can cause one or more the symptoms such as acute or chronic meningitis, abscesses or granuloma encephalitis, stroke, parenchymal brain, or myelopathy. Objective: To assess the frequency of fungal infection as causative agents of meningitis. Patients and methods: Two hundred patients with meningitis, who admitted to three hospitals (name hospitals) in Baghdad, were enrolled in this study from May 2016 to January 2017.The detection methods based on clinical and laboratory criteria and PCR using primers sequence for ITS gene for identification of fungus at species level. Results: The current study showed that, the percentage of aseptic meningitis among immune-compromised patients   was 31 samples. The age ranged between (1-78) years. The male to female ratio was 1:1.08. The prevalence of ITS gene was 15.5% detected by PCR, rRNA gene sequencing provides accurate identification information, with the best results obtained of ITS1, ITS4 sequencing. Candida albicans and Cryptococcus neoformans had the highest positive percentage among other species. Conclusion:  molecular technique by using PCR is sensitive and accurate tool for diagnosis fungal meningitis. ITS gene is important for detection of fungus in CSF sample. Candida albicans and Cryptococcus neoformans are most commen species caused fungal meningitis.Keywords: Cryptococcus, Candida, Aspergillus, molecular detection of fungal meningitis.

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