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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 6 Documents
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Search results for , issue "Volume 08 Issue 10: (2016) October 2016" : 6 Documents clear
FUNCTIONALITY EVALUATION OF EXCIPIENTS MANUFACTURED BY DIFFERENT MANUFACTURERS BS Muddukrishna
Journal of Global Pharma Technology Volume 08 Issue 10: (2016) October 2016
Publisher : Journal of Global Pharma Technology

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Abstract

Purpose: The main aim of this article is to develop an alternate source for excipients manufactured bydifferent manufacturers. Methods: Four different excipients were selected for this study and evaluated based on theirfunctional characteristics. Results: From the results obtained, the both vendors of the materials were showingequivalent each other when we compared with the monograph specifications, analytical results and functionalitycharacteristics. Conclusion: Functionality evaluation of excipients were determined based on the specificationcomparison, analytical results comparison and finally with functionality characteristics of excipients and their impacton formulation.
Evaluation of Medical Error Status in Various Wards of Shohadaye Ashayer Hospital, Khorramabad, Iran Reza Masoudi
Journal of Global Pharma Technology Volume 08 Issue 10: (2016) October 2016
Publisher : Journal of Global Pharma Technology

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Abstract

Medical errors are known as the most important challenges that healthcare systems in all countries areencountered to them. To provide security and safety for patient is one of the major items in the health care systems. Confessing medical errors imposed on patient and education system is found to be an important aspect of medical ethics and care in turn lowers incidence of errors. Given the importance of identifying and reporting occurred medical errors, the present research aimed to assess medical errors in hospital wards of Shohadaye Ashayer Hospital Khorramabad so that findings of this research can inspire us to incorporate medical errors as a very important subject in the curriculum of medical students and finally physicians can do best examination and treatment with minimal or no errors and inaccuracies. The present research is descriptive in nature which lasted from April to March 2015. Statistical population (subjects) included employees and supervisors, nurses, staffs, lab safety facilitator, pharmacy safety facilitator, surgery room personnel, equipment and personnel in the hospital wards, including the emergency department, men surgery, women surgery, operating room, orthopedics, internal medicine ward, neurology, laboratory room, surgery, infectious, ophthalmic, reception, pharmacy and CCU hospital in Shohadaye Ashayer Hospital- Khorramabad. Keywords: Medical Error, Shohadaye - Ashayer Hospital, Khorramabad, Iran.
E-CADHERIN-A SURROGATE MARKER AND ITS RELATION TO OTHER BIOMARKERS IN EARLY STAGES OF DIABETIC NEPHROPATHY IN EASTERN PROVINCE OF SAUDI ARABIAN POPULATION Moattar Raza Rizvi
Journal of Global Pharma Technology Volume 08 Issue 10: (2016) October 2016
Publisher : Journal of Global Pharma Technology

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Background: At present, it is very arduous to reliably envisage which, and when, diabetic patients will developnephropathy and progress to kidney failure. Therefore, preventing diabetic nephropathy or delaying the disease progression bysearching for novel biomarkers is very important. Objective: Determination of diagnostic and prognostic significance of solubleE-cadherin (sE-cadherin) and cystatin C as novel biomarkers of diabetic nephropathy in type 2 diabetic (T2D) Saudi patients.Patients and Methods: Type 2 diabetic patients (n=50) with urinary albumin excretions (UAE) > 300 mg/day (n=16)macroalbuminuria, between 30-300 mg/day (n=14) microalbuminuria and without urinary albumin excretions (UAE < 30 mg/24h) (n=20) normoalbuminuria and 15 controls were enrolled in the study. sE-cadherin, Serum Cystatin C, beta2-microglobulin,urinary microalbumin levels, and creatinine clearances were determined in all groups. Results: There was significant increasein the values of fasting blood sugar(FBS), serum creatinine, NAG, b-microglobulin, Hb1Ac in different groups. There was nosignificant change of Hb1Ac and serum creatinine between diabetic mellitus (DM) with normalbuminuria and diabeticnephropathy with microalbuminuria. The diabetic control and DM group presented with no significant change in E-cadherin(p=ns), however there was significant change of E-cadherin between DM with normoalbuminuria and diabetic nephropathy withmicroalbuminuria (p<0,001) and diabetic nephropathy with macroalbuminuria. Serum creatinine, FBS, cystatin C and Hb1Acwere known predictors of E-cadherin as extracted from regression model [Y(E-cadherin)= -1792.2+ 0.51(S.Creatinine)+0.47(FBS)+0.30(Cystatin C)-0.24(HbA1c)]. Cystatin C was significantly increased in DM as compared to diabetic control (p<0,001),however there was no change between DM normoalbuminuria and diabetic nephropathy microalbuminuria (p=ns). Furtherthere was significant increase in the values of Cystatin C in diabetic nephropathy with macroalbuminuria as compared todiabetic nephropathy with microalbuminuria and normoalbuminuria. Linear regression model of cystatin showed only Ecadherinand b-microglobulin as independent variables [Y (cystatin C) = 0.301+0.559(E-cadherin) + 0.363(β-microglobulin)].Conclusion: In conclusion, this study demonstrated that E-cadherin and cystatin C might play an important role in thedevelopment of early diabetic nephropathy and their measurement might become a useful and noninvasive marker thancreatinine or β2-MG for early incipient diabetic nephropathy as well as for the evaluation of renal involvement of T2D patients.
Use of Iranian Medicinal Plants Effective on Male Fertility Indices Mahnaz Yavangi
Journal of Global Pharma Technology Volume 08 Issue 10: (2016) October 2016
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Abstract

This systematic review article was conducted to report medicinal plants that are effective on male fertility indices. To conduct this review, search terms fertility or pregnancy combined with medicinal plants, herb, and phyto were used to retrieve relevant publications indexed in ISI, PubMed, and Iranian scientific databases. Escanbil, Fumaria parviflora L., Apium graveolens L., Achillea millefolium inflorescence, Urtica dioica L., Withania somnifera L., Phaleria macrocarpa, Satureja khuzestanica, Achillea millefolium, Malva sylvestris, Humulus lupulus L., Allium cepa, Petroselinum crispum, Carthamus tinctorius, and Zingiber officinale were reported to be medicinal plants with fertility indices-promoting properties. Medicinal plants that are used in Iran affect hormonal compounds and other effective compounds on hormonal system as well as the proliferation and viability of sex cells due to their antioxidant properties, and therefore enhance fertility in human and animals. Keywords: Physiotherapy, Infertility, Pregnancy, Iran.
A Survey on Peroxide Content and Acidity level of Persian Doughnuts (Zoolbia and Bamieh) in Lorestan Province, West of Iran Abdolrahim Kazemi Vardanjani
Journal of Global Pharma Technology Volume 08 Issue 10: (2016) October 2016
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Introduction: There are different chemical food contamination that causes detrimental effects on human health. For example, presence of peroxide in fried foods causes free radical formation. Free radicals are not only responsible for food spoilage, but also cause damage to body tissues and cancer, inflammatory diseases, atherosclerosis, aging and so on. The aim of this study was to evaluate the peroxide content and acidity level in Zoolbia and Bamiehin Lorestan province, West of Iran.Materials and Methods: 120 samples of Zoolbia and Bamieh doughnuts were purchased of Lorestan province distribution centers, during March 2014 to March 2015 and handled to Laboratory for chemical analysis and determination of their peroxide value and acidity.Results: present descriptive study results showed 56.92 and 43.07 % of the samples were out of standard limit and not suitable for consumption due to high levels of peroxides and acidity, respectively. The lowest and highest peroxide value were 1.1 and 2.9 mEq/kg, respectively.  The minimum and maximum acidity of the samples were 0.7 and 2.9 wt%, respectively.Conclusion: Obtained results showed high peroxide contents in Persian doughnuts in Lorestan province than standard limit.Therefore, it seems educational programs about nutrition and using proper method for cooking and frying of foods is necessary. Continuous planning and surveillance, providing practical solutions by health authorities and regulatory organs, training of food staffs, using oils a few times and especial for food frying are recommended to reduce the peroxide content in Persian doughnuts (Zoolbia and Bamieh). Keywords: Zombie and Balmier, Acidity, Peroxide, Lorestan province, Iran
A Systematic Review of Iranian Medicinal Plants Effective on Female Infertility Mahnaz Yavangi
Journal of Global Pharma Technology Volume 08 Issue 10: (2016) October 2016
Publisher : Journal of Global Pharma Technology

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Abstract

Infertility is one of the common and rising problems of women. To treat female infertility, medicinal plants may be used in addition to chemical drugs and assisted reproductive technology. To conduct this review, the terms Fertility and Pregnancy in combination with Medicinal plants, Herb, and Phyto were used to search for and retrieve relevant publications indexed in international databases ISI and PubMed and domestic databases Iran Medex and ISC. The articles that fulfilled the inclusion criteria were analyzed. In this systematic review article, the medicinal plants that were found to be effective on female infertility indices were reported. These plants, according to this review article, are Nigella sativa, Panax ginseng, Phoenix dactylifera L., salep, Glycyrrhiza glabra, Apium graveolens L., and Foeniculum vulgare Mill. The medicinal plants used by Iranian people have been reported to exert optimal effects on female fertility in animal studies through antioxidant properties, increasing follicogenesis, hormonal compounds, and other effective compounds on hormonal system as well as enhancing sex cells viability. Keywords: Infertili1ty, Female, Medicinal plants, Iran.

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