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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 70 Documents
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Search results for , issue "Volume 10 Issue 05: (2018) May2018" : 70 Documents clear
The Effect of Focus and Attention and Its Correlation with the Accuracy of Spike Performance with the Rotation and Deception in Volleyball Majid Hameed Merzah
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

The current study aimed to identify the relationship of statistical research to the effect of concentration and attention and their relation to the accuracy of the performance of the spike and rotation of the volleyball of the sample of the research, which was subjected to the test of the impact of concentration and attention to volleyball and the skill test dealt with the study. The researchers used the experimental method to suit the nature of the research, where the study was conducted on a sample of students of the second stage in the Faculty of Physical Education / Karbala University for the academic year 2017 (2018) and represent the age group (20 - 22) years, the number of (60) students, (80%) of the original research community were selected by random method. The researcher used the following statistical means (Percentage, mean, standard deviation, and correlation coefficient - Pearson). The researchers concluded that the concentration and attention test showed a significant correlation in the spike test and the volleyball deception.Keywords: Focus and attention, He spike of rotation, The spike of deceit and volleyball.
OCT Angiography in the Diagnosis of Small Choroidal Tumors Elena Myakoshina
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Introduction small choroidal melanoma is a malignant tumor with early metastasis. It is similar to delimited hemangioma, choroidal nevus and choroidal metastatic carcinoma. The main sign of tumors is their own vessels diagnosed with various methods. However, optical coherence tomography angiography (OCT-A) was not used before. Purpose of this research is to study and compare the OCT-A criteria in the cases of small melanoma, delimited hemangioma, choroidal nevus and choroidal metastatic carcinoma cases. Methods in small melanoma, delimited hemangioma, choroidal nevus and choroidal metastatic carcinoma cases, there was performed a prospective and non-randomized OCT-A with a NIDEK RS-3000 Advance Optical Coherent Tomography (Japan). Results this method was used to examine 120 patients with small choroidal melanoma (41), delimited choroidal hemangioma (32), choroidal nevus (37) and choroidal metastatic carcinoma (10). Tumors thickness: degree – 2.2 ± 0.3 mm, diameter – 8.1 ± 0.6 mm. In the case of small melanoma, vascular network is loop-shaped with elements interweaving under the retinal vessels. In the case of delimited hemangioma, we have pictured a rich tree-like vasculature organized as a large trunk with branches (20) and diffuse scattered one organized as many small convoluted vascular branches (12). In the case of choroidal nevus, we have detected a capillary-free zone with dilated choriocapillarises around the periphery. In the case of choroidal metastatic carcinoma, vascular system was organized as a web of small vessels. Conclusion OCT-A allows diagnosing the features of angioarchitectonics in small melanoma, delimited hemangioma, choroidal nevus and choroidal metastatic carcinoma cases to provide further adequate eye-preserving treatment.Keywords: Small Choroidal Melanoma, Choroidal Delimited Hemangioma, Choroidal Nevus, Choroidal Metastatic Carcinoma, Optical Coherence Tomography Angiography (Oct-A). 
Calcium Status with Some Inflammatory Markers in the Blood of Pregnant Women with Diabetic in Al-Samawa City/Iraq Habiba Khdair
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Background: Diabetes mellitus (DM) is a group of metabolic diseases regarded as by hyperglycemia resulting from defects in insulin action, insulin secretion or both. The chronic hyperglycemia of DM is related with dysfunction of Kidneys and long-term damage, heart, blood vessels, and nerves. Menstruation in Women with Diabetes: Menstrual abnormalities, especially irregular rotations, are common in diabetic women, particularly in those with obesity and poor diabetic control. Many women with DM type 1 diabetes have ovulatory rotations, with secondary or oligo amenorrhea although oligo menorrhea is more common among diabetic women than general population Materials &Methods:  colorimetric analysis for Glucose concentration; had been applied for Erythrocyte Sedimentation Rate (ESR), Alkaline Phosphatase (ALP), Ca+2, and serum C-reactive protein (CRP) test *. Results & Conclusions : In this study There is a significant increase in (ESR, glucose, ALP,  Ca+2  level in pregnant patients as comparison the control group (P < 0.0383- 0.0002),  but  no significant in ( CRP level) in  pregnant patients as comparison the control group ,  there is  no significant difference between (ESR, Glucose, ALP,CRP , Ca+2) level in  pregnant patients with duration of the disease between patients ( duration  <12 weak) & (( duration  12-24) weak )  .There is a significant difference between ( Ca+2 ,CRP level ) level in  pregnant patients  with duration of the disease between patients ( duration  <12 weak) &( duration  > 24 weak). There is no significant difference between (ESR ,Glucose , ALP ) level in  pregnant patients  with duration of the disease between patients ( duration  <12 weak) &( duration  > 24 weak) There is a significant difference between (Ca+2,Glucose  ,CRP  ) level in  pregnant patients  with duration of the disease between patients ( duration  12-24 weak) &( duration  > 24 weak) . There is no significant difference between (ESR, ALP) level in pregnant patients with duration of the disease between patients (duration 12- 24 weak) & (duration > 24 weak).Key words: Glucose, Alkaline phosphatase (ALP), and Calcium (Ca) ;titer ELISA method for C-reactive protein (CRP) and vertical 20cm Western tube for erythrocyte sedimentation rate ( ESR).
Relationship between STK39 Genotype and Vitamin D3 in Hypertension Zahraa Sabbar Omran
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

Vitamin D is a lip soluble molecule obtained through exposure to sunlight and intake of foods containing this nutrient naturally. A diet deficient in vitamin D3 in conjunction with inadequate sun exposure causes osteomalacia, the study was designed to relation between STK39 genotype and vitamin D3 in hypertensive, In study included 70 hypertensive patients with no signs and symptoms of renal impairment and another 30 control subjects .The links between genotype and vitamin D3 in hypertension were examined. The results showed that there were Vitamin D3 deficiency is present in 82.2% of the female hypertension group compared with 17.8% in control group, and There is a significant association between STK39 genotype and 25 (OH)D3 at (p=0.02) particularly in males .
New Turbidity Method to Determine of Calcium Ion in Pharmaceutical Preparations Samples Shaymaa Ibrahim Saeed
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

A new turbidity method was used to determination of calcium ion in the pharmaceutical preparation samples. The proposed method was supported reagent and sodium dodecyl sulfate (SDS) as anionic surfactant. The main factors affecting was study such as  order addition effect,  pH  solution, concentration of reagent, concentration of surfactant, effect of equilibrium temperature and incubation time, effect of interferences. The calibration curve was linear in the range of 0.3-30.0 µg /ml with a correlation coefficient r2 = 0.9996 at pH 4.42. The relative standard deviation obtained 0.0656, and the limit of detection was 1.0 µg /ml. The method used in this research has been successfully utilized in the estimation of Ca (II) in pharmaceutical preparations samples.Keywords: Calcium ion, Turbidity, Cloud point extraction, Sodium dodecyl sulfate.
Effect of Edible Coating and Storage to Shelf Life of Orange Fruit during Storage Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

Orange fruit has high moisture content and nutrient composition make this fruit more susceptible to sofening, browning, or color change and microbial contaminations. It rapidly deteriorates during handling, transport and storage. Edible coatings are widely used for extension of shelf life of fruits and vegetables by reduction of moisture loss and gas exchange as well as reduction of the physiological disorders. The objective of the present study was to identify the effect of different CMC concentrations (1%, 2%, 3%, 4%, 5%) and storage temperature (8 o C, 12 o C, 16 o C, 20 o C) to the weight loss, firmness, total soluble sugar and ascorbic acid in orange fruits during preservation. Moreover, shelf life (0 day, 7 days, 14 days, 21 days and 28 days) of orange fruit in storage also clarified. Results demonstrated that CMC 4% and storage temperature 8 o C could maintain orange fruit quality for 28 days without any deterioration.Keywords: Edible Coating, Orange Fruit, Shelf Life
Comparative Study for Measurement the Diameter of Red and White Muscle Fibers in two Iraqi Fish Species Barbus Grypus (Heckel, 1843) and Barbus Sharpeyi (Gunter, 1874) Mohammed W. H. AL-Muhanna
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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The present study conducted to study the measurement of red and white muscle fibers in two Iraqi fish species (Barbus grypus and Barbus sharpeyi) belonging to the cyprinidae family specimens of fish collected from AL-Hindyiah river at Kerbala province using gill net and cast net. The results declare clear differences in the mean values for the different studying length groups of both species under investigation. The mean diameters of red muscle fibers were less than that of white muscle fibers diameter at different regions of the the body and studying length groups.  The results revealed that the diameter of red muscle fibers ranged from (40.68 - 73.32 microns) in comparison with (69.58 – 102.41 microns) for white muscle fibers for both species. On the other hands the results revealed that diameter of both red and white muscle fibers decrease toward the posterior region of the body, which is perhaps related to the mechanism of movement or swimming of the fish.Keywords: Barbus grypus, Barbus sharpeyi, Red muscle fibers, White muscle fibers.
Evalution of the Effect of Gigaspora Margarita and Glomus Desriticola Fungi in Stimulating the Resistance of the Capsicum Annuum L. plant towards Chromium and Lead Thamer A. A. Muhsen
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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The present study was conducted to evaluate the effect of fungi Gigaspora margarita and Glomus desriticola in stimulating the resistance of the capsicum annuum L. towards the chromium and lead after 60 days, planting and using the pots in the glass house. The highest concentration of chromium and lead in the root was found in the presence of the mycorrhizal mixture (194.93, 150.40) μg / g, respectively, compared to the lowest concentration (90.69, 79.37) μg / g respectively, while the highest concentration of chromium and lead in the shoot was found in the presence of the mycorrhizal mixture (94.63, 79.33) μg / g respectively, compared with the lowest concentration in the control treatment (72.58, 60.70) μg / g respectively. The results showed the highest uptake efficiency and low translocation and phytoextraction efficiency of chromium and lead (179.73, 0.49 and 19.56) μg / g respectively for chromium and (144.63, 0.53 and 15.29) μg / g respectively for lead. The highest percentage of mycorrhizal mixture was recorded in the Intensity of the Mycorrhizal Colonization in the root System and root Fragments reached to (23.61, 26.50) % respectively, while the lowest percentage in mixing (chromium+lead) was (13.22, 13.47) % respectively. The highest percentage of mycorrhizal dependency was found in the mycorrhizal mixture with mixing (chromium+lead) which was 193.16% compared with the least of mycorrhizal dependency in Gigaspora margarita reached 98.34%. The lowest magnesium content in the control treatment was 28.36 mg / dry weight while the mycorrhizal mixture recorded the highest content of 33.41 mg / dry weight. The highest activity of guaiacol peroxidase and glutathione reductas in the treatment of the mycorrhizal mixture and mixing to heavy metals was (50.93, 10.11) absorption unit / gw fresh roots respectively compared with the lowest activity of the enzyme in the control was (31.48, 3.55) absorption unit / gw fresh roots respectively, all the tables showed significant differences.Key words: Pepper plant, AM fungi, Heavy metals, Magnesium, Antioxidants enzymes.
The Efficacy of Vinegar against Contaminated Bacterial Isolates from the Hospital Environmental Ashwaq MS Al-Jbouri
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Objective Hospital environment can represent an important source of pathogens which high risk for patients. Acquired antimicrobial resistances is the major problem .Aims of this study to detection the common contaminant bacteria among the hospital environment and determine the antimicrobials activity of agents (Apple vinegar, Garlic vinegar, Dates vinegar, Raisin vinegar) against pathogenic bacteria isolated from hospital environment. Method In the study 172 samples were taken by swabs from three hospitals in Hilla city, from October 2016 to march 2017.Antimicrobial activity test of (apple, palm, garlic and black raisins) vinegar was determined by  MIC and Agar-well diffusion assay, alsoantibiofilm Formation and ant adherence activity of vinegar against microbes were determined. Result In this study, 172 samples were taken from three Hospitals in Hilla city the result showed that 73 (42.44%) samples were positive cultured and 99 (57.55%) negative cultured from total samples. Staphylococcus aureus37 (33%) was highly isolated from other microbes followed by Bacillus anthrax. Conclusion Staphylococcus aureus is more common in Hospitals in Babylon Provence, vinegar is the most effective substance that killing bacteria that contaminate hospital environment.Keyword: Hospital environment, Vinegar, Antimicrobial agents, Adhesion, Biofilm production.
Increased Risk of Multibacillary Leprosy among Patient with Low Plasma Vitamin D Level Luh Made Mas Rusyati
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Introduction: Leprosy is an emerging transmitted disease that still prevalent enough in Indonesia. Although its treatment modalities have proved to be effective, an effective preventive measure is still needed especially to prevent the development of the severe form of Leprosy. Several studies found that Vitamin D had a significant influence on the immune system and thus could potentially alter the susceptibility to Leprosy or its manifestation. Thus, this study aimed to evaluate whether the plasma vitamin D level had a significant effect on the manifestation of Leprosy. Methods: A case-control study was conducted from July to August 2016 at Dermatology and Venerology Department of Sanglah General Hospital. The leprosy was categorized into Paucibacillary (PB) and Multibacillary (MB) while plasma vitamin D level was classified into normal/high and low. Subjects with MB were included in the case group while those with PB act as acontrol.Results:50 subjects, 25 per group, were enrolled in this study in which no significant differences were found in baseline characteristics of both groups. Bivariate analysis showed that plasma vitamin D level was significantly higher in PB than in MB (24.4272 ng/ml vs. 20.1488ng/ml). In accordance to mean difference, it revealed that low plasma vitamin D significantly increase the risk of MB type leprosy (OR: 12.667; 95% CI: 3.308-48.504). Conclusion: Low plasma vitamin D level significantly increased the risk of MB type leprosy as much as 12.667 times higher than normal.Keywords: Paucibacillary Leprosy, Multibacillary Leprosy, Plasma vitamin D level.

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