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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 65 Documents
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Search results for , issue "Volume 10 Issue 08: (2018) August 2018" : 65 Documents clear
The Effect of Special Visual Exercises in the Development of Visual Tracking and the Accuracy of Spike in the Volleyball for Young Players Bassem Hassan Ghazi
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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The Aims of Research to: Preparation of visual exercises, especially in the development of visual tracking and the accuracy of the spike of the volleyball young players. To identify the impact of exercise visual especially in the development of visual tracking and the accuracy of the spike of the volleyball of young players. The Hypothesis: Special visual exercises have a positive effect on the development of visual tracking and the accuracy of the volleyball spiking of young players. As for the research method, the researchers chose the experimental approach as the appropriate method to solve the research problem by designing the experimental and control groups with the tribal and remote tests as it fits the nature of the research problem. The sample of the research was chosen from the research community represented by the young players in the volleyball of the middle region (3 clubs) in Iraq at the age of 17-19 years and the number of (36) player has been selected two clubs, including the number of (20) player after the expulsion of the player prepared randomly by lot to represent the two groups Experimental and control of the sample of the search and the reality of (10) player for each group. The Researchers Concluded: An evolution in visual tracking and accuracy of the volleyball team's spike in volleyball skill, There is a preference for the experimental group in the tests of the dimension of visual tracking and the accuracy of spiking in the volleyball, The various special exercises developed by the researchers contributed to the development of visual tracking and the accuracy of the spiking skill. The Recommendations Were: The need to use special visual exercises to develop the visual tracking of players, especially young people, The need to use special visual exercises to increase the accuracy of the skill of spiking, The need to use special visual exercises to increase the excitement and excitement of young people and increase their motivation for training.Keywords: Visual exercises, Accuracy, Spike and volleyball.
Production and Preservation of Marian Plum (Bouea Macrophylla) Nectar Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Marian plum (Bouea macrophylla) belongs to the cashew family (Anacardiaceae). The ripe fruit is yellow-orange, mango-like in character, roundish, and juicy with a sour to sweet taste according to the variety, and has a faint turpentine smell. The endosperm is white and pinkish purple, and has a bitter and astringent taste. Ripe fruits are consumed fresh, but sometimes they are made of whole or pieces of fruit in sugar syrup. It has a lot of vitamins and nutrients that’s good for health. In order to enhance its added value, this study focused on production and preservation of marian plum nectar. The effect of pH, sugar supplementation, temperature and time of pasteurization to sensory score of marian plum nectar; changes of total soluble solid, acidity and microbial load in marian plum nectar during storage were examined. Results showed that marian plum nectar had the best quality by adjusting at pH 4.2, sugar supplementation 6%, 95oC in 2.5 minutes, storage at 4 ± 2 ºC in glass bottle.Keywords: Bouea macrophylla, Supplementation, Pasteurization, Storage, Nectar, Acidity
GC/MS Analysis of Terpenes of Boswellia Serrata Resin Found in Iraq Noor S Jaafar
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Objective: The aim of this work was to detect terpenes other than boswellic acid derivatives in olibanum of Boswellia Serrata found in Iraq. Methods: The olibanum of Boswellia Serrata was macerated in methanol for one day, then filtration.  Filter at was concentrated till reddish brown syrupy residue was gained, (3%) potassium hydroxide was added till basification. This basic solution was stirred continuously until a uniform emulsion was formed, then extracted with chloroform in a separatory funnel; the chloroform fraction was analyzed by GC /MS spectrometry. Results: GC /MS analysis reveal the presence of terpenes and non-terpenes constituents.  Conclusion: Most of the detected terpenes were sesquiterpenes and the least one was di-terpenes.Keywords: Boswellia Serrata, Olibanm, Terpenes, Gas Chromatography- Mass Spectrometry.
Confirmatory Detection of Escherichia Coli O157:H7 in Diarrheic and Non-Diarrheic Calves by using Real Time PCR with Studying the Antimicrobial Susceptibility of these Bacteria Mustafa Salah Hasan
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Shiga toxigenic E. coliO157:H7 is one of the Shiga-toxin producing types of E. coli, which can produce disease in man and animals. The aims of this study were to detect O gene (rfbO157) and H gene (fliCH7) and determine the pattern of antimicrobial susceptibility of 32 E. coli O157:H7 isolates. The isolates isolated by conventional culture methods and latex test from faecal samples of 4 calves suffering from diarrhoea and 28 calves’ apparent normal. DNA was extracted from these isolates and the real time PCR was applied on the extract of DNA for confirming the diagnosis ofrfbO157 and flic H7 genes. Seven antimicrobial discs were used in this study. The result presented that all the (32) isolates were possessed the rfbO157 and flics H7 genes. The susceptibility test of the isolates revealed that all isolates were highly resistant to Erythromycin (100%) and Cephalothin (96.87 %). Less resistance to Tetracycline, Trimethoprim-Sulfamethoxazole and Chloramphenicol at different percentage (31.25%), (12.5%) and (9.37%) respectively and all isolates showed high sensitivity to Gentamicin (100 %), Enrofloxacin (100 %). In conclusion, the real time PCR can be used as a sensitive and reliable tool for diagnosis of E. coli O157:H7 and these bacteria showed high resistance to antibiotic.Keywords: E. coli O157:H7, real time PCR, rfbO157, flic H7, antibiotic susceptibility.
The Addition of Caffeine in EBSS Media by Sperm Swim-up Washing Method Increased the Human Sperm Motility and Acrosomal Reaction Bagus Komang Satriyasa; J. Alex Pangkahila
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Background: Caffeine, a methylxanthine derivate, had a role as a phosphodiesterase inhibitor, thereby inhibiting the break down of cAMP and increasing its concentration inside the cell. Aim: This study aimed to assess the effect of caffeine in EBSS and evaluated the increase in motility and the acrosomal reaction of spermatozoa using the swim-up method. Method: This was an experimental study using a pre-post test control group design. This study was carried out at the Sexology and Andrology Clinic, Sanglah Hospital in Denpasar Bali. The samples were sperm specimens of eighteen infertile male or volunteers aged 20-40 years. They were divided into two groups: treatment group (caffeine + EBSS) and control group (EBSS). The data were analyzed statistically by normality test (Kolmogorov – Smirnov Goodness of Fit Test), homogeneity test and paired student’s t test. Result: The caffeine addition in EBSS medium increased the sperm motility significantly from 71.94% to 80.28% (p<0.05) and the acrosomal reaction from 83.33% to 88.89% (p<0.05). Conclusion: The addition of caffeine in EBSS medium increased the motility and the acrosomal reaction of the human sperm.Keywords: Caffeine, EBSS, Sperm motility, Acrosomal reaction, Spermatozoa.
Technical Factors Affecting to the Dried Mango (Mangifera Indica) Leaf Tea Production Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Abstract

Mango (Mangifera indica L.) was a juicy stone fruit belongs to the family of Anacardiaceae. Mango fruits were an important source of micronutrients, vitamins and other phytochemicals. Mango (Mangifera indica) leaf was used as astringent, refrigerant styptic, vulnerary and constipating. They are also useful in vitiated conditions of cough, hiccup, hyperdipsia, burning sensation, hemorrhages, haemoptysis, haemorrhoids, wounds, ulcers, diarrhoea, dysentery, pharyngopathy, scorpion string and stomachopathy. The ash of burnt leaves was useful in burns and scalds. The smoke from burning leaves was inhaled for relief of throat diseases. Tea is among the most consumed natural beverages worldwide due to its great benefits. Young leaves of mango (Mangifera indica) could be dried into herbal tea for aqueous extraction. Mangiferin is a major constituent of the leaves and stem bark of Mangifera indica. Objective of this search focused on investigating different processing aspects regarding to mango leaf tea while maintaining the most mangiferin content. Results were shown that the dried mango leaf would preserve mangiferin content by blanching the fresh mango leaf at 95oC, 4 seconds at size 2cm, then drying at 30oC by heat pump, and finally packing in PET/AL/PE bag at 4oC. By this approach, the dried mango leaf tea could be kept until 12 months without significant deterioration of mangiferin content.Keywords: Mango leaf, Mangiferin, Blanching, Drying, Packing, Tea.
The Removal of Pharmaceuticals and Personal Care Products (PPCPs) as Mixture from Water Stream by Ozonation: The Effect of pH and Retention Time on PPCPs Removal Hind M. Ewadh
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Pharmaceuticals and personal care products (PPCPs) can be found in waste water and even sometimes in drinking water with increasing in the concentration especially within this last decade due to the high usage of medicines in daily life. Ketoprofen (KET) and Ibuprofen (IBU), as an anti-inflammatory drug, 17α- ethinylestradiol (EE2) as synthetic estrogen and Galaxolide (HHCB) as personal care products are found in many water sources with different concentration and they are unremovable by the conventional wastewater treatment and can be found in tap or drinking water. In this research, ozonation was used as removal technique to remove these PPCPs as a mixture by varying the ozonation contact between 15, 22.5 and 30 min and changing in pH value between 6, 7.5 and 9. After ozonation, the removal was recorded between (75-100%) for the selected PPCPs. During the ozonation pH was monitored decreasing in value and degradation occurred and transformed products were detected by GC/MS. Thus, ozonation can be used to remove the PPCPs from the water stream and the highest removal was conducted at pH= 9.Keywords: Pharmaceuticals and personal care products, Ibuprofen, Ketoprofen, 17α-ethinylestradiol, Galaxolide, Ozonation.
Effect of Thyroxine Tablets Treatment on the Oxidative Stress in Hypothyroid Women Al-Shimaysawee Sadeq
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Objective: Although some researches informed increased oxidative stress (OS) in hypothyroidism, the influence of treatment with levothyroxine is did not considered widely. Hence, we directed this article to examine the influence of levothyroxine therapy on oxidative stress in hypothyroid women. Methods: The current study included 42 women hypothyroid patients treated with thyroxine& 25 untreated in addition to 40, age matched healthy females used as a control group. The thyroid function test, serum reduced glutathione (GSH), catalase (CAT) and glutathione-S-transferases (GST) levels were measured. Results: The results showed that serum GSH level revealed significant increases in hypothyroid untreated patients. In contrast, GSH treated level showed nonsignificant increases when compared with those of the control group, but the results of CAT levels failed to indicate significant variation in the two groups while the serum GST level revealed significant decreases in hypothyroid untreated patients in contrast, GST treated level showed nonsignificant increases when compared with those of the control group. Highly significant (p<0.01) positive correlation was obtained for GSH levels with thyroxine in treated hypothyroid women whereas CAT levels failed to exhibit significant correlation with throxine tablets treatment also Significant (p<0.05) positive correlation was obtained for GST levels with thyroxine in treated hypothyroid women. Conclusions: Hypothyroidism is associated with elevated oxidative stress and thyroxine tablets are modulate the oxidative stress in treated hypothyroid women patients. Keywords: Thyroxine Tablets, Oxidative Stress, Hypothyroid Women.
The Impact of the Educational Program Using Teaching Aids in Teaching the Skills of Service Receiving and Court Defending for the Students the Volleyball Majid Hameed Merzah
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Abstract

The coaches and experts interested in preparing the volleyball teams from the physical, skill, planning and psychological aspects of their teams, on a set of bases, the most important of which are the basic skills which vary in level of complexity and complexity from one game to another .Based on this sense of importance of these skills, which reduces efforts, shortens time and material possibilities, and makes early learning processes a little more erroneous because errors at these stages, if developed, are difficult to correct. And through the researcher's practice of this game found that these skills are still taught in traditional ways, and educational curricula in the general sphere of volleyball lacks the use of aids and devices that help to accelerate and stabilize the processes of education and consolidate the differences between these skills, the use of traditional methods of learning, which It is not possible to arrive at a precise description or measurement of learning, and non-objective evaluation is accompanied by many errors in accurate monitoring of the movement parts.The Research ObjectsFind educational aids to teach students the skills of service receiving and paying volleyball students.Learning about the impact of the learning program using some educational aids in teaching the skills of service receiving and paying students with volleyball.The researchers used the experimental method in the style of equal groups to suit the problem. The research society determines the students of the second stage in the Faculty of Physical Education and Sports Sciences at the University of Karbala for the academic year 2016-2017 Division (A, B, C) and the number of (82) (24) students, divided into two groups of each group (12) students.The Most Important Conclusions WereThe proposed learning program using innovative teaching methods has a positive impact on teaching service receiving skills.The proposed learning program using innovative teaching aids has a positive impact on the teaching of court defending skill.Keywords: Educational program, Teaching aids, Receiver service and defending of pitch skills.
Preparation, Characterization and Study Antibacterial Activity of Schiff Base and O-(Carboxyl) Chitosan Derivatives Biopolymer Mahmood M. Ahmed
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Thiadiazole, Schiff bases are very important compounds used in the biological and industrial field and for this reason, chitosan has been modified with these compounds. Vehicles are prepared in the following ways. Initially, 2-amino-5-mercapto-4,3,1 tahiadiazole [1] were introduced according to the lectures through the thiosemcarbazide interaction with carbon disulphide in the presence of anhydrous sodium carbonate in absolute ethanol.2-amino-5-mercapto-4,3,1-tahiadiazole was activated with Salicylaldehyde in the presence of ethanol and a compound was obtained [2]. The compound [2] was then reacted with chloroacetic acid in the presence of anhydrous sodium carbonate in the distilled water Obtain the compound [3] .Schiff bases compounds [4-5] Attended with an Anthranilic acid reaction, 4-amino benzoic acid with benzaldehyde derivatives with absolute ethanol .The compounds [3-4], [6] were treated with chitosan (CS) for modulation and compounds [7-9].  The synthesized compounds were characterized by FTIR, 1HNMR, melting point.Keywords: Schiff base, Biopolymer, O-(carboxyl) chitosan derivatives, Antibacterial activity.

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