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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 74 Documents
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Search results for , issue "Volume 11 Issue 04." : 74 Documents clear
Clinical Applications of Doppler Ultrasound in Obstetrics Rowshan Jawad Azeez
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

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Abstract

Ultrasound images of flow, whether color flow or spectral Doppler, are essentially obtained from measurements of movement. In ultrasound scanners, a series of pulses is transmitted to detect movement of blood. Echoes from stationary tissue are the same from pulse to pulse. Echoes from moving scatters exhibit slight differences in the time for the signal to be returned to the receiver. These differences can be measured as a direct time difference or, more usually, in terms of a phase shift from which the ‘Doppler frequency’ is obtained. They are then processed to produce either a color flow display or a Doppler sonogram.
Effects of Soursop (Annona muricata ) Lea f Water Extract (SLWE) on Body Weight, Leptin and TNF α Plasma Levels of Rats with High Fat and High Fructose (HFHF) Diet. Dini Sri Damayanti
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

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Abstract

Abstract Background: Soursop leaves believed to be able to lose weight. The aim of the study was to prove that SLWE had an effect on body weight, leptin and TNF α plasma level in mice with the HFHF diet . Methods:The study used post test group design only. Male Wistar rats aged 8-10 weeks weighing 175-200g, healthy, 25 were divided into 5 groups by simple random sampling. Normal groups (N) , Positive groups (P) were given a HFHF 10% diet, treatment group  (T1), T2, and T3 ( HFHF diet + SLWE at dose of 100 mg / kg bw, 200 mg / kg bw, and 400 mg / kg bw). The diet and extract were given for 10 weeks. Measurement of body weight and weighing the amount of food consumed were carried out every week. Measurement of plasma leptin and TNF α levels using the ELISA method. Statistical analysis using ANOVA and Kruskal Wallis test with a confidence level p <0.05. Results : SLWE at all doses increased the amount of intake compared to P and N groups (p <0.05).Giving SLWE at dose of 400 mg/kgbw causes a slowdown in weight gain (p> 0.05),  increase levels of plasma leptin than P group. There was a tendency to decrease TNF α plasma levels with an increase in the dose of the extract (p>0.05). Conclution : Giving SLWE in HFHF diet-induced mice increased appetite, increased Leptin levels, and tendency to decreased weight gain and TNF α levels.Keyword : Soursop leaf, Weight gain, Leptin, TNF α, High Fat-High Fructose Diet
Hematologic and Clinical Features of Thalassemia Patients with Early or Late Onset Transfusion in East Java, Indonesia Retno Dwi Wulandari
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

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Abstract

Thalassemia is a genetic disorder of hemoglobin production which causes chronic anemia. Complete blood count showed lower HbA, MCV, MCH, increase RDW-CV and increase HbA2 (>3,5%) and HbF (>1,5%). Thalassemia major patients need regular and lifelong blood transfusion which started early in life. Thalassemia intermedia, usually with milder symptoms, require blood transfusion at later age, with lower transfusion rate. This study aims to compare hematologic, HbA2 and HbF profiles as well as height, weight, Body Mass Index and spleen size in thalassemia patients grouped based on transfusion start whether in early or later age (before or after 10 yo). Results showed that the hematologic, HbA2 and HbF profiles were not significantly different in both groups. The clinical profiles i.e. Height and weight were below 3rd percentile in both groups; low BMI and more patients underwent splenectomy in group of those with early onset blood transfusion.Keywords: Thalassemia, Transfusion, Hematologic, Height, Weight, BMI.
Effect of Edible Film Glazing to Physico-Chemical, Microbial and Sensory Attributes of Frozen Pangasius Fillet N. P. Minh
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

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Abstract

Pangasius is a type of catfish that is endemic to the waters of Mekong basin in south-east Asia, belongs to the family Pangasiidae. It is generally processed to frozen fillets for domestic consumption and also exported to Europe and USA. Freezing and cold storage is an efficient method which preserves taste and nutritional value. Glazing is a process used to reduce undesirable drying or dehydration of fish during frozen or cold storage. Objective of the current research studied the feasibility of edible coating in maintaing and preserving the chemical, microbial and sensory attributes of frozen Pangasius fillet. The frozen Pangagius fillets were glazed by different formulas (N0: control or glazing with clean water; N1: 3% w/w chitosan and glycerol; N2: 3% w/w whey protein concentrate and glycerol; N3: 3% w/w alginate an glycerol; N4: 3% w/w carrageenan). The chemical quality was based on the analyzed results of ammonia (µNH3/g) and pH; biogenic amines such as putrescine (mg/kg), cadaverine (mg/kg), histamine (mg/kg), spermine (mg/kg), spermidine (mg/kg); lipid oxidation or malondialdehyde value (mg/kg); microorganism such as Total plate count (cfu/g), Enterobacteriaceae (cfu/g), Coliform (cfu/g), E. coli (cfu/g), Staphylococus (cfu/g), Listeria (cfu/g), Salmonella (cfu/g), Vibrio (cfu/g); sensory score. All treated frozen Pangagius fillets were tested after 12 months of storage. Results revealed that the incorporation of 3% w/w chitosan and glycerol in ice‐glazing could inhibit microbial spoilage and lipid oxidation and therefore maintain the freshness of Pangasius fillet during frozen storage. Under the optimal conditions, the shelf‐life of Pangasius fillet could be extended up to 12 months at −18 °C. The study indicated that the combination treatment with edible coating could be commercially utilized to maintain the freshness and prolong the shelf‐life of frozen Pangasius fillet.Keywords: Frozen, Pangasius fillet, Glazing, chitosan, Glycerol, Whey protein concentrate, Alginate, carrageenan.

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