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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 106 Documents
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Search results for , issue "Volume 12 Issue 06 (2020) June 2020" : 106 Documents clear
Application of the Mamdani Fuzzy Logic Multi Output Method to Maintain Electrical Conductivity in Hydroponic Media for Lettuce (Lactuca sativa L.) and Bok Choy (Brassica rapa L.) Nyi Mekar Saptarini; Mohamad Nurkamal Fauzan
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

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Abstract

Nutrition in hydroponic cultivation affects the electrical conductivity (EC) that must be controlled to fulfill the plant’s requirement. The aim of this study was to determine the application of the Mamdani fuzzy logic with multi output to maintain the EC value, mixed volume in the tank and real time monitoring the current condition of the system. Case studies on lettuce (Lactuca sativa L.) and bok choy (Brassica rapa L.). The controlled system was NodeMCU and Arduino nano with analog pH, EC meter as input and pumps as an actuator. The results show that this application maintains an average EC value of 1.96 mS/cm and an average mixed volume of 53.4%. Plant conditions were sent to Android device in real time monitoring. The comparison data of manual and automatic (Mamdani fuzzy logic) monitoring were similar. Keywords: Lactuca sativa L., Brassica rapa L., Mamdani, multi output, real time monitoring
Effects of DHA-Enriched Fish Oil Supplements on Dopamine Receptor Gene Expression in the Cerebral Cortex and Hippocampus Related to the Male Rat’s Weight Gain Fifi Veronica
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

Background: Docosahexaenoic acid (DHA) can penetrate through the barrier between the blood and the brain through simple diffusion and obtains benefits for neurons. Supplementation of DHA-enriched fish oil for seven weeks in young male Wistar rat could alter dopamine (DA) receptor modulation, and it may be related to the increased weight gain. Aim: This present study aims to explore the alteration of the dopamine receptors (D1DR and D2DR) gene expression in the cerebral cortex and hippocampal area, as a top-down circuit control, related to the role of body weight gain as an indicator of food intake. Methods: Twenty samples of Rattus novergicus, aged 7-8 weeks, were randomly grouped into two groups as follows: 10 rats as the control group (CG) and 10 rats in the group that received treatment with fish oil -omega 3 capsules (FOG). CG and FOG were fed with standard laboratory food and received water ad libitum. The treated group (FOG) received 0.2 ml added supplementation of DHA-enrich fish oil (FO) capsules with the daily dose of 30 mg EPA and 45 mg of DHA for 7 weeks via gavage every morning. The body weight of each rat was weighed and recorded every 2 weeks. Results: The weight had increased significantly in the FOG during the first 4 weeks of treatment and continued to grow until the end of the 7 weeks of treatment (p=0.036). The relative D1DR gene expression in the cerebral cortex was significantly higher compared to the relative expression mRNA in the hippocampus region (D1DR 1.6 fold, p
Risk Behavior of Tiom Community Related with Helminthiasis at Lanny Jaya District, Papua Province, Indonesia Gurendro Putro
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

Background: Helminthiasis is an infectious disease which is one of the severe health problems in Indonesia. The worm can reduce intelligence, inhibit the growth of children, and even cause death. The behavior of a clean and healthy life is expected to be able to encourage the community to improve the quality of daily health behaviors to cope with helminthiasis. Objective: to assess risk factors in healthy hygiene behaviors that has the potential to cause helminthiasis. Method: A descriptive retrospective research. The material is interviews form and library data assessment. Data collection is done by listening, direct recording, recording audio, and video provided. Data retrieval is done by the time-limited sampling method. The data obtained were processed and analyzed descriptively. Results: It was found that the community consisted of local communities and migrants. The risk factors for clean and healthy living that have the potential to cause helminthiasis are divided into two, namely: (1) Hygiene and living environment sanitation (2) Personal hygiene and sanitation which includes; the habit of washing hands is still low, not wearing footwear, the practice of cutting nails that are still weak, open defecation habits, bathing habits that are very rarely done, drinking water and eating raw food (3) Risk of eating pork at a "barapen" stone grilling ceremony. Conclusion: Risk factors in healthy hygiene behavior that have the potential to cause helminthiasis are health sanitation of residential, inadequate personal hygiene, and cooking pork at a "barapen" stone grilling ceremony, which is considered insufficient to kill worms. Keywords: Clean and healthy lifestyle, Helminthiasis, Tiom, “Barapen” Ceremony, Tiom, Papua Indonesia.
Human Sperm Chromatin Maturation: A Study of Prolactin Supplementation in Sperm Preparation Silvia W Lestari
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

One of the management of infertile couples is assisted reproduction through the Intra Uterine Insemination (IUI). Paternal factor has been known to influence the success of IUI, such as sperm selection on preparation. Prolactin (PRL) is reported to select sperm with better DNA fragmentation on the preparation process. This study aimed to investigate sperm selection with better chromatin maturation quality, by the supplementation of PRL. Semen samples were obtained from 10 infertile men who experienced sperm preparation for IUI. Prepared sperm were incubated at 1000 ng/ml of PRL, followed by chromatin maturation test. Its index was determined as mature sperms in 100 sperms. The differences in sperm chromatin maturation showed a significant difference (p
Changes of Phytochemical, Antioxidant Characteristics of Sunflower Seed Roasting Minh Phuoc Nguyen
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

Sunflower seeds have various target specific biological activities. There has been an increase of awareness and interest in this valuable medicinal plant in recent times. Roasting is the key process in the production of value-added nuts having better taste, aroma, and a crunchy texture and exhibit enhanced crispiness. However changes of phytochemical, antioxidant characteristics of sunflower seeds during roasting have not been well understood. This research evaluated the roasing method affecting the phytochemical and antioxidant characteristics of sunflower seeds. The total polyphenol, flavonoid contents, the antioxidant activity characteristics in sunflower seeds were examined thoroughly. It may be desirable to use roasting at 200oC in 15 minutes to minimize the loss of total polyphenol, total flavonoid contents; maintain the most antioxidant activity. Keywords: Sunflower seed, Roasting, Total polyphenol, Total flavonoid, Antioxidant.
The Study of Morbidity Structure in Children Using Automated Computer Technology Dmitriy Karlov
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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The combination of new computer and electronic technologies with methodologies for analysing large databases is considered efficient for increasing the effectiveness of screening methods for detecting diseases. Aim of the research is to study the effectiveness of using an automated complex of dispensary examination (ACDE) for detecting pre-nosology conditions and pathologies of organs and systems in children compering to traditional medical examinations. 948 children aged 6 to 17 years were examined. There were 437 (46.1%) boys and 511 (53.9%) girls. The average age of children was (11.36 ± 1.25) years. First, all children underwent a traditional preventive medical examination, and then a programmed medical examination for all organs and systems using an automated complex of dispensary examinations. The following diseases predominated according to the structure of pathology among the children examined: the musculoskeletal system (in 74.3% of children), cardiac pathology (in 52.5% of children), dental diseases (in 51.4% of children), and diseases of the nervous system (in 48.6% of children) and ophthalmic pathology (in 46.5% of children). The detection frequency of pre-nosology conditions / pathology of organs and systems using the automated complex of dispensary examinations is significantly higher (p

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