cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 106 Documents
 1   2   3   4   5 
Search results for , issue "Volume 12 Issue 06 (2020) June 2020" : 106 Documents clear
Semiautomated On-line for the Determination of Sitagliptin Phosphate using UV-low Pressure Mercury Lamp at 184.9 nm and 253.7 nm at ISNAG-fluorimeter Analyzer Nagam S. Turkey Al-Awadie
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (919.039 KB)

Abstract

New methodology for sitagliptin phosphate determination via on-line continuous flow injection manifold design of sitagliptin phosphate-phosphomolybdic acid (PMA) system. The method was applied using continuous flow injection system of a new homemade ISANG -fluorimeter with turbidity measurements at 900 via 2×4 solar cell. Chemical and physical parameters were studied and optimized. The calibration graph was the linear dynamic in the range of (0.1-4.5 mmol.L-1) which was better representation, with correlation coefficient r=0.9965 .The limit of detection (LOD) 35.999µg/sample from the stepwise dilution for the minimum concentration in the linear dynamic ranged of the calibration graph. The method was successfully applied for the determination of sitagliptin phosphate (STP) in two pharmaceuticals preparation of different companies. A comparison was made between the newly developed method analysis with the classical method (UV- spectrophotometry at λ max =267 nm) using the standard addition method via the use of individual and paired t-test and F-test. It was noticed that there was a significant difference between two methods at 95 % confidence level. Keywords: Sitagliptin phosphate, Turbidity, Flow injection analysis. Introduction
Food Poisoning and Its Prevention on the Example of Listeria Monocytogenes Ekaterina Savelyeva
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.395 KB)

Abstract

Listeriosis is one of the most serious and severe foodborne diseases characterized by a high mortality rate of 20% to 44%. The purpose of the research is to study the age-related features of the clinical symptoms of listeriosis in adults, as well as the influence of comorbid conditions on its course. The study included 73 patients with listeriosis (43 (58.9%) men and 30 (41.1%) women; average age (48.83 ± 6.29) years). They were divided into 2 groups: group 1 (n = 29) - patients aged 18-49 years, group 2 (n = 44) - patients aged over 50 years. Septicemia is most common clinical syndrome in patients with listeriosis, presented in 46 (63%) patients. It’s followed by damages of the central nervous system, namely meningitis and meningoencephalitis in 26 (35.6%) patients; gastroenteritis in 10 (13.7%) patients; and skin lesions in 3 (4.1%) patients. Septicemia was a typical clinical syndrome for patients over 50 years old - in 33 (75%) patients compering to 13 (44.8%) in the younger age group (OR = 3.69, 95% CI [1.36-10.04]). The damages of the central nervous system, namely meningitis and meningoencephalitis were typical for younger age group - 16 (55.2%) patients while 10 (22.7%) cases among the older age group (OR = 4.18, 95% CI [1, 51-11.56]). The mortality rate was 27.4% (of which 80% of deaths occurred in the older age group). Listeriosis is characterized by a severe course and a high mortality rate from septicemia and CNS damages. It is the cause of concomitant pathology development in immunocompromised individuals. Keywords: Adult listeriosis, Age-related features of listeriosis, mortality in listeriosis, Comorbid conditions and listeriosis, Prevention of listeriosis.
The Potential Healing Properties of Systemic Probiotic-Prebiotic Supplement on Angular Cheilitis Malath Nabil Jafar
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (505.062 KB)

Abstract

Background: Angular Cheilitis frequently caused by anemia and malnutrition such as iron, B12, folate and zinc deffiency, but can also be caused by fungi. Probiotics are live organisms thought to benefit human health. Aim of the study: to test the efficacy of probiotics in the healing process of angular Cheilitis in elderly individuals. Materials & Methods: The sample included 58 individuals (both genders) with clinically apparent angular Cheilitis. The duration of the disease was between 8-10 days. The age ranged between (55-65) years. Probiotic-prebiotic food supplement selected to be used is (max biotic XL) sachets. Results: the majority of recovery cases recorded during the 2nd week in both genders, females showed better response as compared to males. The recovery potential declines with age. Conclusion: The main conclusions that have obtained in this research that the treatment is effective 89.5% for both genders. And it is more effective for females than males, the healing time for most patients is two weeks, and the treatment is more effective on age 60 for both genders. Keywords: Probiotics, Prebiotics, Cheillitis, Supplement, Healing.
Breast cancer awareness and breast screening practice among women in Yogyakarta Susi Ari Kristina; Nada Nisrina Salsabila
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.615 KB)

Abstract

Background: Low public knowledge and understanding, contributing to late diagnosis, has identified cancer morbidity and mortality from breast cancer. This study was designed to describe breast cancer knowledge and awareness and evaluate breast screening practice among Yogyakarta women. Methods: A cross-sectional study of 350 low socioeconomic women in rural and urban Yogyakarta areas was conducted using a validated self-designed structured questionnaire. Analyzing data using descriptive statistics. Results: A vast majority of respondents knew that breast cancer is a severe disease (85.14%) and can be detected as early as possible (60.00%). Genetic and family cancer history was the best accepted risk factor for breast cancer (61.43%), followed by oral contraception (44.57%), radiation (31.43%), smoking (28.86%) and alcohol intake (21.71%). Over half of respondents (65.14%) correctly identified niple and color discharge as one of the symptoms of breast cancer, followed by breast lump (60.00%), breast swelling (56.29%) and breast fluid (44.57%). While 56.57 percent of respondents had heard of breast self-examination ( BSE) and mammography, only 26.86 percent of respondents had regularly performed BSE, and only 28.00 percent of respondents reported daily mammography. A large proportion of respondents (72.86%) never diagnosed breast cancer. Conclusion: In Yogyakarta, the study reported inadequate breast cancer awareness and poor breast screening practice among women with low socioeconomic status aged 20-50 years. Health care professionals are fairly required to educate women about breast cancer and promote early detection and breast cancer screening programs to prevent and reduce breast cancer incidence and mortality.
Effect of Topical Serratiopeptidase on Facial Wound Healing in Rabbit Faehaa A. Al-Mashhadanee
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (774.015 KB)

Abstract

Abstract Objective: Serratiopeptidase (SRP), an enzyme with great effect in opposing inflammation. Applications of enzyme topically provide advantage of direct entery to the location of action. This study examined the possibility of using topical SRP preparations in the formula of ointments and to assess the topical effect of SRP in facial wound management in rabbits. Material and Method: healthy male rabbits weight,1.25 ± 0.25kg divided into four groups: group one animals received no treatment, group two animals treated with Vaseline only, group three and four were treated by SRP (0.5% and 1%) respectively. Standard incisions were done on submandibular region of all rabbits. Wound healing assessment was determined by histological method. Results: group one and two showed incomplete closure of the wound with poor re-epithelization, while other groups (three and four) demonstrated complete closure of the wound with good re-epithelization. Conclusion: topical application of SRP has ability to improve facial wound healing in rabbits. Keywords: Serratiopeptidase, Facial wound, Rabbit.
The Effect of Extract Ciplukan (Physalis angulata L.) to Placental Vessels, Placental Weight and Fetal Birth Weight in Preeclampsia Rat Model Nur Permatasari
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (490.464 KB)

Abstract

Background: Preeclampsia, which is one of the specific diseases of pregnancy at the age of 20 weeks. Preeclampsia is due to the vascular abnormalities of placenta that can cause chronic hypoxia of the placenta and the fetus's nutritional disorder, causing impaired function of the placenta, and fetal development during pregnancy. Physalis angulata L. contains antioxidants, and anti-inflammatory effects in improving placental function and preventing nutritional disorders in the fetus. The study aims to determine the effect of Physalis angulata L. against the number of placental blood vessels (capillaries), the weight of placenta and birth weight fetus on the preeclampsia rat model. Methods: The research is an experimental laboratory study conducted in vivo design consisting of five groups; Negative control group, positive control group (preeclampsia rat model), preeclampsia rat treatment group with therapeutic dose 1, dose 2, and dose 3 (500mg/kg/BB; 1500mg/kg/BB; 2500mg/kg/BB). Counting the number of capillaries with the H&E stain method, the placenta weight and the fetus weight is measured immediately using analytical balances. Data analysis using One-way Annova test. Result: The results showed significant difference of capillaries p value < 0.05 (p = 0,000), the placenta weight p value < 0.05 (0.025), and the birth fetal weight p value < 0.05 (0.002). Conclusion: Physalis angulata L. can be a potential antioxidant in preeclampsia through increased eNOS and NO level which can improve the function of the placenta in preeclampsia rats so that the number of placenta capillaries increased, while the placenta weight and the fetal weight increased. Keyword: Preeclampsia, Placenta Vessels (capillaries), Placenta Weight, Fetal Weight, eNOS, NO
Theater Performing Art: a Strategy to Improve Self-efficacy and Social Support in Patient with Type 2 diabetes Mellitus (T2DM) Mahendro Prasetyo Kusumo
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (465.589 KB)

Abstract

Background: The lacks of self-efficacy and social support are two neglected issues in patients with type 2 diabetes mellitus (T2DM). One of the popular methods to enhance those factors is theater performance art education (TPA), but its evidence in T2DM is lacking. Therefore, this study was aimed to measure the effectiveness of TPA toward social support and self-efficacy in T2DM. Methods: This study used quantitative methods with a quasi-experimental non-equivalent pre post-test control group design. The two variables measured were self-efficacy and social support. The subjects of this study were Prolanist member of patients with T2DM in the four primary health care centers in Sleman Yogyakarta Indonesia. Pre-test and post-test measurement were taken and compared to determine the efficacy of the TPA. Results: 102 subjects were used in this study (32 in control and 70 in intervention group) with women and 45-60 years old age group comprised the majority of the subject population. Mann-Whitney test showed that the self-efficacy score increased more pronouncedly in intervention group compared to control group (Δ mean intervention: 3.34±4.74; Δ mean control: -0.75±3.98; p: 0.000). Same result was also observed in social-support variable (Δ mean intervention: 1.63±1.84; Δ Mean control: 0.38±1.84; p: 0.002). Multiple logistic regression revealed that TPA only significantly affected self-sufficiency (Adjusted OR: 0.173; p: 0.001; 95%CI: 0.062 - 0.479) while barely influenced social support. Conclusion: The implementation of theater performing art-based community empowerment as part of social education helps in improving self-efficacy in patients with T2DM. Keywords: T2DM, Theater performing art, Self-efficacy, Social support.
Electronic Cigarettes Use Characteristics Among Smokers in Indonesia Susi Ari Kristina
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.116 KB)

Abstract

Background: Vape also known as an electronic cigarette that included a set of battery-operated equipment that smoker used to breathe an aerosol, typically conceiving nicotine, flavorings, and other chemicals, and becoming one of the types of a developed cigarette. This study aims to explore the risks and benefits of using electronic cigarettes and investigate factors affecting smokers' use of electronic cigarettes. Methods: This research was a cross-sectional model for Yogyakarta adults using a validated self-administered questionnaire. The questionnaire is divided into three parts: sociodemographic characteristics, smoking, perception of risk-benefit. Data were descriptively and inferentially analyzed using the Chi-square test to investigate factors affecting risk and benefit perception of smokers using electronic cigarettes. Results: Results showed that 133 (66.5 percent) were vape users, and 67 (33.5 percent) were tobacco smokers. Most tobacco smokers and vape users in Yogyakarta province have a high perception of electronic cigarette risk-benefit. Respondent characteristics (age, last education, smoking status) significantly influenced the benefit perception of electronic cigarettes, and smoking status on respondent characteristics also significantly influenced the risk perception among smokers of electronic cigarettes (p
Health Coaching to Improve Mother’s Self Efficacy in the Implementation of Prevention Malnutrition in Children Yuni Sufyanti Arief
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (481.651 KB)

Abstract

Introduction. One of the factors causing nutritional problems that can be modified and has an influence on the nutritional status of children under five is the pattern of parenting or child care by the mother, because the mother is a personal preference in fulfilling family nutrition. The family will play an important role in preventing nutritional deficiencies in each member of the family. The purpose of this study was to examine the effect of health coaching on maternal self-efficacy in preventing malnutrition. Method. Quasy-experimental design with pre-post control group was used as a method in this study. A total of 30 parents were used as respondents, divided into 15 for the treatment group and 15 for the control group. The sampling method used was purposive sampling based on inclusion criteria. Self-efficacy as the dependent variable and health coaching as the independent variable. The data were collected by means of a questionnaire and analyzed using the Wilcoxon rank sign test and the Mann Whitney U test with a significance level of ≤ 0.05. Results. The results showed the wilcoxon results for the treatment group p 0.008, the control group showed a p score of 1,000. Mann Whitney test showed a p score of 0.003. Conclusion. Health coaching is effective in increasing maternal self-efficacy in preventing malnutrition. The mechanism of change is by changing the Health inhibiting Thinking (HIT) in the mother to become Health enhancement Thinking (HET). The results of this study can be used as an alternative health promotion method.
Physico-Chemical Attributes of Soursop Fruits during Storage under Treatment of 1-Methylcyclopropene (1-MCP) Minh Phuoc Nguyen
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (433.348 KB)

Abstract

Owing to high moisture content, soursop (Annona muricata) fruit has a short shelf-life by turning soft and bruised easily after harvesting. It quickly becomes unacceptable for fresh consumption. This valuable fruit should be preserved for a long shelf life. However, the lack of improved postharvest technology limits it on domestic and foreign markets. This research evaluated the effectiveness of 1-methylcyclopropene in different concentration (0, 50, 100, 150, 200 ppm) to shelf-life of soursop fruits during 12 days at ambient temperature storage. The use of this ethylene inhibitor at 150 ppm improved the shelf-life and quality of soursop fruit, including lower weight loss, maintain firmness, retent ascorbic acid and soluble solid during preservation Keywords: Soursop, 1-methylcyclopropene, Preservation, Firmness, Weight loss, Soluble solid, Ascorbic acid, Post-harvest.

Page 2 of 11 | Total Record : 106

 1   2   3   4   5 

Filter by Year

2020 2020


Reset
Filter By Issues
All Issue Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue