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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 3 Documents
 1 
Search results for , issue "Volume 12 Issue 07 (2020) July 2020" : 3 Documents clear
Nanogels as Next Generation Drug Delivery Systems Sri Sruthi K; Satya Lakshmi S; Srinivasa Rao Y; Kamala Kumari P.V
Journal of Global Pharma Technology Volume 12 Issue 07 (2020) July 2020
Publisher : Journal of Global Pharma Technology

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Abstract

Nanogels are the innovative drug delivery systems which plays an integral part in pointing out many issues related to old and modern courses of treatment, such as nonspecific effects and poor stability. Nanogels are the highly cross linked nanosized hydrogels ranges from 20-200 nm. These can also be administered through various routes, including oral, pulmonary, nasal, parenteral, intraocular etc. Nanogels have high degree of drug loading capacity and it also shows better permeation capabilities due to a smaller size. These are also release the drug by pH responsive, thermosensitive, volume transition, photochemical internalization and photo-isomerization mechanism.Withemerging field of polymer sciences it has now become an inevitable to prepare smart nanosystems which can prove effective for treatment as well asclinical trials progress. The present review providing the comprehensive illustrations on novel applications, drug loading technique, mechanism of the drug release from nanogels. Further, current status, clinical trial status, and future perspective of the nanogels have been summarized.
Model of Physical Activity (Gambo Rasa) on Type-2 Diabetes Mellitus Glucose Level in Working Area of Bolo Health Center Abdul Haris
Journal of Global Pharma Technology Volume 12 Issue 07 (2020) July 2020
Publisher : Journal of Global Pharma Technology

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Abstract

Introduction: The principle of managing diabetes mellitus consists in setting management goals, modifying diet and exercise, medication, monitoring blood glucose levels, monitoring complications regularly, and evaluating laboratories. In addition to these principles, four main pillars of diabetes mellitus management were more concise to understand, which include education, diet, exercise, and medicine. Exercise was considered important for diabetes mellitus management because it can cause physiological effects such as lowering blood glucose levels, lowering fat levels the body, decreases blood lipid levels, lowers blood pressure, and improves fitness. Methods: The research design used was "one group pretest-posttest design", researchers examined changes that occur after an intervention. Data were analyzed using paired sample t-test. Results: The results showed that there was an influence of the physical activity model (Gambo Rasa) on blood glucose levels of type-2 diabetes mellitus. Keywords: Model of Physical Activity, Gambo Rasa; Type-2 Diabetes Mellitus; Blood Glucose
Pharmacoepidemiology of Antiretroviral Drugs in a Tertiary Care Teaching Hospital Pragna Malavika Malavika B; Saravana Kumar RT; Lakshmi BVS
Journal of Global Pharma Technology Volume 12 Issue 07 (2020) July 2020
Publisher : Journal of Global Pharma Technology

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Abstract

Background: India has a large population using antiretroviral drugs (ARV) which has potential therapeutic efficacy and high toxic properties resulting in diverse adverse drug reactions (ADRs). Adherence to the ART is a crucial challenge to be addressed as it plays a major role in the success of HIV management. Aim: To determine the prescribing pattern of antiretroviral drugs uses at an ART center and the levels of adherence to the drugs and the associated adverse effects. Materials and methods: It is a retrospective analysis of the clinical records related to HIV-infected adults who were receiving treatment at an ART Center in Andhra Pradesh state. The main outcomes of the study are demographic details of the patients, the pattern of ART combinations prescribed, adherence to the given ART, and analysis of reported ADRs. Simple descriptive statistics and chi-square tests are the statistics used to measure the outcomes. Results: A total of 430 HIV patients’ records were selected and assessed. Tenofovir (TAF)+ Lamivudine (3TC) +Efavirenz (EFV) (66.5%) was the most prescribed ARV combination. The majority of 348 patients (80.9%) were good adherence and showed a significant association with therapeutic outcomes. The most common clinical ADRs found in this study were gastrointestinal disturbances (30.9%) followed by dermatological problems (20.4 %). Conclusion: Despite drug toxicity, ART treatment bears potential therapeutic efficacy and is considered as the only means to increase life expectancy in HIV infected patients. Detailed patient counseling and monitoring improve therapeutic outcomes and patients adherence.

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