cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 3 Documents
 1 
Search results for , issue "Volume 12 Issue 12 (2020) Dec. 2020" : 3 Documents clear
Empagliflozin Managed Type 2 Diabetes Mellitus in Insulin induced Hypertension: A case report Raja A; Sadagoban GK; Jemi Rachel Shaji; Renita Castelino; Swathi Swaroopa Borra
Journal of Global Pharma Technology Volume 12 Issue 12 (2020) Dec. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (400.555 KB)

Abstract

Insulin is an essential hormone and has been the cornerstone in the therapy of Diabetes Mellitus. This case highlights insulin-induced hypertension in a type 2 DM patient, managed adequately with empagliflozin. A 60-year female with Diabetic Nephropathy & Hypothyroidism presented with elevated blood pressure after a week of insulin administration. An elevation in the patient’s blood pressure corresponding to the administration of insulin was observed. De-challenge and re-challenge of insulin with dose adjustment, resulted in sudden spike & decrease of blood pressure, thereby pointing a suspicion towards a relation between insulin and hypertension. Discontinuation of insulin and replacement with oral hypoglycemics has resulted in controlled blood pressure levels.
Cefazolin as a Prophylactic Antibiotic in Laparoscopic Cholecystectomy: A Systematic Review Tjokorda Gde Agung Senapathi
Journal of Global Pharma Technology Volume 12 Issue 12 (2020) Dec. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (449.66 KB)

Abstract

Background: Cefazolin is a first-generation cephalosporin prophylactic antibiotic which recommended for open cholecystectomy. Laparoscopic cholecystectomy is a clean contaminated surgery that does not require prophylactic antibiotics. Some surgeons still have the habit of giving prophylactic antibiotics for laparoscopic cholecystectomy. This systematic review aimed to examine evidence from randomized controlled trials comparing the incidence of surgical wound infection with cefazoline use. Methods: We collected randomized controlled trials (RCTs) throughout the years 2010-2020 from the Cochrane Library and PubMed in English language, which examined the incidence of surgical wound infection between the cefazolin prophylactic antibiotic groups versus placebo on laparoscopic cholecystectomy. Results: Six RCTs were included in the final analysis for a qualitative assessment using the Jadad scale, with four articles in the high category and the other two in the good category. The incidence of surgical wound infection in the cefazolin group was 1.09-4.8% (mean 2.63%) and did not differ significantly from the placebo group. Old age (> 60 years), obesity, timing of antibiotics, as well as tissue trauma and billiard spill during laparoscopic cholecystectomy were not significant factors. Conclusion: The prophylactic antibiotic cefazolin was not significant in reducing the incidence of surgical wound infection in lapaoscopic cholecystectomy. It is necessary to review the guidelines for prophylactic antibiotics in each health service place. Keywords: Cefazolin, Prophylactic antibiotics, Laparoscopic cholecystectomy, Surgical wound infection.
Investigation of Binding Efficacy of Pectin Isolated from Solanum betaceum Cav using Tabletting Technology Benedict Jose C
Journal of Global Pharma Technology Volume 12 Issue 12 (2020) Dec. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pectin’s are widely used in food industry and Pharmaceutical industry. It is also a natural part of the human diet. The current research work deals with the isolation and preliminary characterization of pectin from tree tomato (Solanum betaceaum Cav) and further to evaluate its binding property with starch and Poly Vinyl Pyrollidone (PVP). The pectin was subjected to phytochemical and physicochemical characterization and its suitability to use as binding agent. FT-IR spectroscopy, DSC studies were performed for drug, Solanum betaceaum Cav pectin (SBP) powder and the tablets were prepared with isolated pectin and other binders. Paracetamol tablets were prepared by wet granulation method containing mannitol and microcrystalline cellulose as diluents, using 4%, 8% and 12 %w/w of SBP, starch and PVP as binding agents in the tablet formulation. Precompressional properties of granules and tablets such as Carr’s index, Hausner’s ratio and angle of repose and quality control tests like weight variation, thickness, friability, hardness and disintegration time were determine and found satisfactory. The in vitro release studies shows that release rate of drug is decreased with increase in the SBP percentage in the formulation. Solanum betaceaum Cav pectin powder showed good binding. The binding efficiency of Solanum betaceaum Cav pectin was comparable with binding character of starch 12% and PVP 8%. The pectin isolated from Solanum betaceaum Cav can be used as binder in the formulation of tablets. Keywords: Solanum betaceaum Cav pectin, Fruit pectin, Tree tomato, Tamarillo pectin, Natural binder, Natural excipients.

Page 1 of 1 | Total Record : 3

 1 

Filter by Year

2020 2020


Reset
Filter By Issues
All Issue Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue