cover
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2 Documents
Search results for , issue "Volume 13 Issue 04 (2021) April 2021" : 2 Documents clear
Discovery of Potential Inhibitors against Mainprotease of Sars Cov2 from Centella Asiatica by in Silico Study Kavitha K; Mohan S; Umarani G; Soundara Rajan D K; Subra Manian S; Sakila Ban U S
Journal of Global Pharma Technology Volume 13 Issue 04 (2021) April 2021
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (472.683 KB)

Abstract

Centella asiatica encompass be utilize towards healing a set of affliction of humans. Legendary mechanism exemplify to its existence of plenteous genetic activities. In this explore revise be projected to make out the phytoderived antiviral moieties from Centella asiatica against Covid-19 Mpro protein as well as comprehend the Insilico study foundation of molecular activity and during in current examine five isolate molecules in Centella asiatica retrieve as of the PubMed database and be subjected towards docking investigation. Dock analysis were done by using Auto dock vina and PyRx software and followed by admet SAR in addition to pkCSM servers, were used for analyse the drug-likeness prediction. Among 5 Phyto-Molecules, 4 moieties of Centella asiatica are very probable aligned with the Mpro protein of Sars Co V 2. Further, the selected Phyto-molecules on the natural source strength launch consistent prescription and bear frontage discovery. Acknowledged beat molecules could be further in use for in vitro, in vivo evaluation and to investigate their efficiency opposed to COVID-19. Keywords: SARS Co V-2, Main Protease, Centella asiatica, Insilico study, Drug likeness.
Reconstruction of A Huge Soft Tissue Deffect in Flank Region Using Rectus Femoris Flap Meirizal Hasan; Rahadyan Magetsari; Rezky Saraswaty
Journal of Global Pharma Technology Volume 13 Issue 04 (2021) April 2021
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction:Coverage of full-thickness large flank defect is a challenging procedure for surgeons. The rectus femoris (RF) muscle flap is an excellent donor muscle for many reconstructions. The vascularized rectus femoris (RF) muscle flap has been proved to be effective to cover infected vascular grafts in the flank region. Outcome of the treatment can be evaluated by evaluating the patient daily activity. Case Report:This was a case report conducted on patient with huge soft tissue deffect in flank region. A 62 years old male with large defect of the right flank region due to infection of the abdominal cavity after appendectomy 2 months ago. The wound size 15 x 7 x 7 cm, with the base is bowel, with serohemoragic discharge. Then perform debridement and rectus femoris flap. A month after operation, the patient came to the Sardjito General Hospital with defect of the right hypogastric region and then VAC was performing in this patient. Two month after VAC, the wound was covered by granulating tissue and then the patient underwent FTSG. A month after the second operation, the patient came to outpatient clinic, able to walk, with the condition of the wound was good, no visible sign of infection. Conclusion:From this case report shows that rectus femoris flap has a good result to coverage the huge soft tissue defect in flank region. The patient can perform a simple daily living. Keywords: Rectus femoris, Flank defect, Flap.

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