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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 4 Documents
 1 
Search results for , issue "Volume 16 Issue 04 (2024) April 2024" : 4 Documents clear
AGE-STRATIFIED PREVALENCE AND ANTIBIOTIC RESISTANCE PATTERNS OF HELICOBACTER PYLORI INFECTION AMONG PATIENTS UNDERGOING UPPER GASTROINTESTINAL ENDOSCOPY IN A TERTIARY CARE HOSPITAL, INDIA Ahmad, Imtiyaz; Hassan, Syed Belal; Mustaqueem, Syed Fiza; Ahmad, Ausaf
Journal of Global Pharma Technology Volume 16 Issue 04 (2024) April 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The infection rate of H. pylori varies significantly between developing and developed nations, with rates approximately four to five times higher in developing countries. Antibiotic misuse has contributed to resistance issues, complicating eradication efforts. Study aimed to assess age-specific H. pylori prevalence and antibiotic resistance among patients undergoing Upper Gastrointestinal Endoscopy at a tertiary care hospital in India. Study included patients aged 14 to 86 presenting with symptoms like dyspepsia and epigastric pain. Demographic data and treatment history were collected, excluding recent antibiotic or proton pump inhibitor users. Statistical analysis was performed using SPSS version 16.0. Results indicated an overall prevalence of 61.1%, with similar rates across genders. Infection rates peaked at 73.7% in patients above 70 years. Positive endoscopic findings correlated significantly with H. pylori infection, underlining the importance of endoscopic evaluations. Notably, symptoms like epigastric pain were linked to H. pylori positivity. The study concluded that H. pylori prevalence is notably high in individuals above 70 years old. Additionally, it shed light on gender-specific prevalence patterns and highlighted metronidazole resistance as the most common, followed by levofloxacin and amoxicillin resistance. Furthermore, the study stressed the importance of endoscopic examinations in diagnosing H. pylori infection. Keywords: Antibiotic Resistance, Dyspepsia, Epigastric pain, H. pylori, Prevalence.
BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF OXACEPROL IN HUMAN PLASMA BY USING UV-VISIBLE SPECTROPHOTOMETER Sri, K. Bhavya; Banu, Shaheen; Sumakanth, Mogili
Journal of Global Pharma Technology Volume 16 Issue 04 (2024) April 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Osteoarthritis is commonly treated with oxaceprol. An easy, quick, accurate, and exact technique for estimating oxaceprol is required since 1 billion people worldwide suffer from rheumatoid arthritis each year. Utilizing a UV-visible spectrophotometer, procedures are developed and then validated. Only a few techniques for estimating oxaceprol have been described, but after reviewing the literature, we developed a method with a wide linearity range and low DL and QL values. Methanol: ACN was used as the solvent in the development of this procedure. The chosen wavelength for examination in this approach was discovered to be 215nm. To do the spectrum study, a double beam spectrophotometer with UV and visible light was employed.In the UV spectrophotometer, the absorbance of several series of dilutions was measured at a wavelength of 215 nm. Oxaceprol concentration was plotted on x-axis & absorbance was taken on y-axis to plot Calibration curve. All the validation parameters were validated as per ICHQ2 (R1) guidelines. Keywords: Osteoarthritis, UV-visible spectrophotometer, linearity, calibration curve, methanol.
AGE-STRATIFIED PREVALENCE AND ANTIBIOTIC RESISTANCE PATTERNS OF HELICOBACTER PYLORI INFECTION AMONG PATIENTS UNDERGOING UPPER GASTROINTESTINAL ENDOSCOPY IN A TERTIARY CARE HOSPITAL, INDIA Ahmad, Imtiyaz; Hassan, Syed Belal; Mustaqueem, Syed Fiza; Ahmad, Ausaf
Journal of Global Pharma Technology Volume 16 Issue 04 (2024) April 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The infection rate of H. pylori varies significantly between developing and developed nations, with rates approximately four to five times higher in developing countries. Antibiotic misuse has contributed to resistance issues, complicating eradication efforts. Study aimed to assess age-specific H. pylori prevalence and antibiotic resistance among patients undergoing Upper Gastrointestinal Endoscopy at a tertiary care hospital in India. Study included patients aged 14 to 86 presenting with symptoms like dyspepsia and epigastric pain. Demographic data and treatment history were collected, excluding recent antibiotic or proton pump inhibitor users. Statistical analysis was performed using SPSS version 16.0. Results indicated an overall prevalence of 61.1%, with similar rates across genders. Infection rates peaked at 73.7% in patients above 70 years. Positive endoscopic findings correlated significantly with H. pylori infection, underlining the importance of endoscopic evaluations. Notably, symptoms like epigastric pain were linked to H. pylori positivity. The study concluded that H. pylori prevalence is notably high in individuals above 70 years old. Additionally, it shed light on gender-specific prevalence patterns and highlighted metronidazole resistance as the most common, followed by levofloxacin and amoxicillin resistance. Furthermore, the study stressed the importance of endoscopic examinations in diagnosing H. pylori infection. Keywords: Antibiotic Resistance, Dyspepsia, Epigastric pain, H. pylori, Prevalence.
BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF OXACEPROL IN HUMAN PLASMA BY USING UV-VISIBLE SPECTROPHOTOMETER Sri, K. Bhavya; Banu, Shaheen; Sumakanth, Mogili
Journal of Global Pharma Technology Volume 16 Issue 04 (2024) April 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Osteoarthritis is commonly treated with oxaceprol. An easy, quick, accurate, and exact technique for estimating oxaceprol is required since 1 billion people worldwide suffer from rheumatoid arthritis each year. Utilizing a UV-visible spectrophotometer, procedures are developed and then validated. Only a few techniques for estimating oxaceprol have been described, but after reviewing the literature, we developed a method with a wide linearity range and low DL and QL values. Methanol: ACN was used as the solvent in the development of this procedure. The chosen wavelength for examination in this approach was discovered to be 215nm. To do the spectrum study, a double beam spectrophotometer with UV and visible light was employed.In the UV spectrophotometer, the absorbance of several series of dilutions was measured at a wavelength of 215 nm. Oxaceprol concentration was plotted on x-axis & absorbance was taken on y-axis to plot Calibration curve. All the validation parameters were validated as per ICHQ2 (R1) guidelines. Keywords: Osteoarthritis, UV-visible spectrophotometer, linearity, calibration curve, methanol.

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