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Journal of Pharmaceutical and Sciences.

jps
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Published by Universitas Tjut Nyak Dhien

ISSN : - EISSN : 26563088 DOI : https://doi.org/10.36490/journal-jps.com

Core Subject : Health, Science, Agriculture, Engineering,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 68 Documents

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Search results for , issue "JPS Volume 6 Nomor 2 (2023)" : 68 Documents clear

Efektivitas Minyak Jintan Hitam (Nigella Savita Linn) Terhadap Bakteri Staphylococcus epidermidis yang Terdapat Pada Ulkus Diabetik Indah Armaya Ningrum; Rena Meutia
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia (increased blood sugar levels) that occurs due to defects in insulin secretion, insulin action, or both. Black cumin oil (Nigella Savita Linn) is a species in the genus Nigella, which includes about 14 species of plants that contain oily solids, namely unsaturated fatty acids, arachidic acids and eicosadienoic acids, proteins, alkaloids, saponins, essential oil. The aim of this study was to determine the antibiotic activity of black cumin oil (Nigella Savita Linn) on Staphylococcus epidermidis bacteria and to determine the concentration of black cumin oil (Nigella Savita Linn) which can inhibit the growth of Staphylococcus epidermidis bacteria. The results obtained at concentrations with concentrations of 1 mg/mL, 0.75%, 0.5%, and 0.25% have an antibiotic effect on the growth of Staphylococcus epidermidis bacteria found in diabetic ulcers. The differences in the antibiotic effects of black cumin extract (Nigella Savita linn), namely concentrations of 1%, 0.75%, 0.5%, and 0.25%, have significant differences in inhibition so that it can be concluded that black cumin oil (Nigella sativa linn), significantly statistically significant (p and <0.05) inhibited the growth of Staphylococcus cholermidis in diabetic ulcers. The higher the concentration of black seed oil (Nigella sativa) the greater the inhibition zone formation.

Review Artikel: Formulasi Lipstik Dengan Menggunakan Bahan Alam Sebagai Pewarna Alami Nia Yuniarsih; Amelia Putriana; Dyah Kharisma Ariyanti; Ina Nurunnisa; Muhammad Gilang; Sahrul Setiawan; Tasya Putri; Tia Laelasari
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Lipstick is a cosmetic product used to color lips, giving an artistic effect on the face that can enhance the aesthetics of facial make-up. Besides being able to provide attractive colors, this lipstick must also contain dyes that are safe to use. As a natural ingredient in making lipstick, various natural ingredients can be used in the form of extracts such as leaves, flowers, fruit and others. The method used in this study consisted of database searches through Pubmed, Science Direct and Google Scholar for various scientific articles published between 2013 and 2023. And the purpose of this study was to determine the composition of lipsticks that use natural ingredients as natural dyes. Literature search results that meet these criteria yield up to 20 references. Based on a review of various scientific literature, extracts from natural ingredients can act as natural dyes.

Review Artikel: Validasi Metode Analisis Penetapan Kadar Parasetamol Dalam Sampel Biologis Dengan Berbagai Metode Tiwi Ambarati; Najla Yusiana Wahyudi; Saarah Hamidah Asmara Indratno; lina Nurfadhila; Marsah Rahmawati Utami
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Paracetamol is one of the most widely used pain relievers and analgesic drugs by the public. Examination of drug concentrations in biological samples using appropriate methods is necessary to ensure drug quality and optimize drug therapy. Therefore, this literature study was conducted with the aim of determining paracetamol levels in biological samples and testing its validity with various methods. Literature research was carried out by searching for several research journal articles that had been published in 2013-2023, which were selected according to the inclusion and exclusion criteria. Six journals were obtained regarding the validation of analytical methods for determining paracetamol levels in biological samples using various methods such as Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS), Mass Spectrometry-High Performance Liquid Chromatography (HPLC- MS), and Mass Spectrometry Ultra High-Performance Liquid Chromatography (UHPLC-MS). From the above review it can be concluded that the method of analyzing paracetamol compounds in biological samples can be carried out with these four methods where the results of the analytical methods namely accuracy, selectivity, linearity, precision, LOD, and LOQ all meet the requirements or set criteria.

Analisis Kualitatif Senyawa Parasetamol Pada Sampel Biologis Menggunakan Metode Gas Chromatography - Mass Spectrometry (GC-MS) Siti Nuriah; Mutia Desvi Putri; Sri Rahayu; Chalisya Vanya Advaita; Lina Nurfadhila; Marsah Rahmawati Utami
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

In this review article, an analysis was carried out regarding the use of the Gas Chromatography - Mass Spectrometry (GC-MS) method in the qualitative analysis of paracetamol compounds in various biological samples such as blood, serum, hair, and urine. Paracetamol is a non-opioid analgesic drug used to relieve mild to moderate pain. The method used in writing this article is a literature study using primary data in the form of national journals from the Google Scholar and Sinta databases. The search was carried out using keywords related to the qualitative analysis of paracetamol compounds using the GC-MS method on biological samples. The purpose of reviewing this article is to compare the treatment and preparation processes of various biological samples used in the qualitative analysis of paracetamol compounds using the Gas Chromatography - Mass Spectrometry (GC-MS) method, such as blood, serum, hair, and urine. The results of the study of several journals showed that there were several biological samples used in the qualitative analysis of paracetamol using the GC-MS method, namely blood, serum, hair and urine. Each biological sample has different preparation and extraction procedures according to the characteristics of the matrix. It can be concluded that of the four samples, hair samples can show positive results in a longer period of time while blood and urine samples can only provide drug information for a few days.

Review artikel: Metode Analisis obat Tuberkulosis Dalam Plasma Darah Datu Muhammad Cordova; Shiyami Aulia Nur Darmawan; Mutiara Alfiyah; Marsah Rahmawati Utami; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Tuberculosis is a respiratory disorder that is contagious and is caused by an infection with the bacterium Mycobacterium tuberculosis (aerobic bacteria). Treatment of tuberculosis usually uses first-line drugs, namely isoniazid, rifampicin, ethambutol and pyrazinamide. The purpose of this study was to review the effectiveness of developing HPLC or UPLC methods with UV and MS detectors to review tuberculosis drug concentrations in biological blood plasma samples. The author's search method in compiling the results of a journal review regarding the development of methods for analyzing anti-tuberculosis drugs (OAT) in biological blood samples using databases from Google Scholar and Pubmed®. A total of 26 relevant journals will be used for discussion in the journal review. The results obtained are the most widely used method in the analysis of OAT using HPLC/UPLC mass and ultraviolet detectors in a biological sample, blood plasma. It has been reported in several studies that the UPLC method has increased sensitivity as indicated by a decrease in LOD and LOQ values compared to the HPLC method.

Perbandingan Metode Analisis Kadar Senyawa dan Toksisitas Merkuri (Hg) dalam Sampel Biologis Priscinya Christiana Debora; Sofianti Hidayat; Mochamad Galuh Ryandha; Marsah Rahmawati Utami; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Mercury or mercury (Hg) is a type of metal as an organic and inorganic compound that can be found in nature and is spread in rocks, ores, soil, water and air. Mercury in the body can be detected in biological materials such as urine, blood, breast milk and hair. This study aims to analyze the content and toxicity of mercury (Hg) in biological samples such as blood, hair, urine and breast milk with various analytical methods including CV-AAS, AAS, CV-AFS, ICP-MS, FI-CV-AAS, and Mercury Analyzers. Data collection was based on the Literature Review by collecting several published research journals both at national and international levels which were filtered according to inclusion and exclusion criteria using the PRISMA method (Preferred Reporting Item for Systematic Review and Meta-Analysis). The method used depends on the needs of the analysis, its sensitivity and availability. Of the several methods used, AAS or atomic absorption spectrophotometry is the most commonly used method, because this method is simple and considered fast for analyzing mercury levels in biological samples.

Artikel Review: Analisis Obat Metamfetamin Dalam Sampel Rambut Dengan Berbagai Metode Syifa Khairunnisa; Eka Wulan Galuh Pratiwi; Anggi Ayu Pratama; Marsah Rahmawati; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Methamphetamine is a narcotic substance commonly known as shabu - shabu, which can damage the central nervous system and even cause death so that its distribution is restricted in Indonesia. The content of methamphetamine in the body can be analyzed using biological samples, one of which is hair. Hair is a part of the body that is commonly used to prove the presence of methamphetamine in the body because in the hair a drug can last for a long time, up to months. Writing a review of this article aims to make it easier for readers and researchers. The method of writing a review of this article is by conducting a literature search of research related to the analysis of methamphetamine in biological hair samples. Based on the results of a review of the journal, analysis of methamphetamine in hair samples can be carried out qualitatively and quantitatively with several methods that can be used to detect methamphetamine, including the marquis method, Gas Chromatography Mass Spectroscopy (GC-MS), Graphene Oxide Assisted Membrane Electron Extraction (EME) with Chromatography Gas (GC), and FE-GC/MS.

Validasi Metode Analisis Senyawa Obat Dalam Sampel Biologis (Urine) Shinta Puspa Dwiyanti; Diva Afiah Hanifa Irawan; Zuyyinna Alya Abbas; Marsah Rahmawati Utami; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Urine is one of the selected specimens because the content of metabolites and drugs in urine is relatively high. In addition, the easiest and most stable sample to examine is a urine sample. The aim of this study was to determine a valid analytical method for analyzing drug compounds in biological samples of urine. The research method used was to conduct a literature study on several credible journals with journal criteria for the last 10 years regarding determining drug levels in human urine. The final results were obtained from five different analytes, namely Trimethoprim (TMP), ciprofloxacin, acetaminophen, methanol, and opiates which have been validated using several validation methods namely; HPLC with Photodiode Array Detector (PDA), HPLC with fluorescence detector, capillary electrophoresis with UV detector, spectrofluorometric, Gas Chromatography-Mass Spectrometry (GC-MS), GC-FID, and Spectro photo densitometry using human samples urine, all have met the validation requirements. So, it can be concluded that the biological sample of human urine is quite accurate as the sample used in the analytical validation method.

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Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Salman

Contact Email salman.kimia@gmail.com

Phone +6285277011177

Journal Mail Official admin@journal-jps.com

Editorial Address Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location Kota medan, Sumatera utara INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Salman

Contact Email
salman.kimia@gmail.com

Phone
+6285277011177

Journal Mail Official
admin@journal-jps.com

Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location
Kota medan,

Sumatera utara

INDONESIA