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Patricia Wulandari
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Sriwijaya Journal of Radiology and Imaging Research
Published by Phlox Institute: Indonesian Medical Research Organization
ISSN : 2986853X     EISSN : 2986853X     DOI : https://doi.org/10.59345/sjrir
Core Subject : Health, Science,
Dentistry Health Professions Medicine & Pharmacology Neuroscience Physics
Focus Sriwijaya Journal of Radiology and Imaging Research (SJRIR) focused on the development of medical sciences especially radiology & imaging research for human well-being. Scope Sriwijaya Journal of Radiology and Imaging Research (SJRIR) publishes articles which encompass all aspects of basic research/clinical studies related to the field of radiology & imaging research and allied science fields, especially all type of original articles, case reports, review articles, narrative review, meta-analysis, systematic review, mini-reviews and book review.
Arjuna Subject : Kedokteran - Kedokteran Radiologi Nuklir dan Imaging
Articles 25 Documents
 1   2   3 
Factors Contributing to the Accuracy of PET Scans in Detecting Cancer Metastases in Cairo Hospitals, Egypt Sayeed, Fatmah
Sriwijaya Journal of Radiology and Imaging Research Vol. 2 No. 2 (2024): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i1.118

Abstract

Introduction: Positron emission tomography (PET) has become an important diagnostic tool in oncology, providing metabolic information that can aid in the detection and evaluation of cancer. However, the accuracy of PET scans in detecting cancer metastases can be influenced by various factors, including the type of cancer, location of metastases, and image acquisition protocol. This study aims to evaluate the factors that influence the accuracy of PET scans in detecting cancer metastases in patients at Cairo Hospital, Egypt. Methods: Patient data were collected retrospectively. A total of 5000 research subjects participated in this study. Data were analyzed to identify factors associated with false-positive or false-negative PET scan results. Results: Patients with lung or colorectal cancer were 2.45 times more likely to experience accurate positive PET scan results than patients with other types of cancer. Patients with metastases in lymph nodes were 1.93 times more likely to experience accurate positive PET scan results than patients with metastases in solid organs. Patients with a long PET scan image acquisition protocol were 1.78 times more likely to experience accurate positive PET scan results than patients with a short image acquisition protocol. Conclusion: PET scan is a valuable diagnostic tool in oncology, but its accuracy in detecting cancer metastases can be influenced by various factors. These factors should be considered when interpreting PET scan results and to improve cancer diagnosis and management.
Utilization of Biopsy-Guided CT Scan in Diagnosing Liver Cancer: A Case Study Susanti, Cindy; Agnes Mariska
Sriwijaya Journal of Radiology and Imaging Research Vol. 2 No. 2 (2024): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i1.119

Abstract

Introduction: Liver cancer is one of the most common types of cancer in Indonesia and has a high mortality rate. Early diagnosis of liver cancer is very important to increase the patient's chances of recovery. Biopsy-guided CT scan is an effective method for diagnosing liver cancer. Case presentation: We report the case of a 55 year old man with a history of chronic hepatitis B who presented with complaints of right upper abdominal pain and weight loss. Physical examination revealed hepatomegaly and ascites. Investigations, including abdominal ultrasound and liver function tests, showed a mass in the liver. CT scan of the abdomen with contrast showed a hypodense mass in the right hepatic lobe. A CT-guided liver biopsy was performed and the histopathological diagnosis was hepatocellular carcinoma (HCC). The patient then underwent partial resection hepatectomy and chemotherapy. Conclusion: Biopsy-guided CT scan is a valuable tool for the diagnosis of HCC in patients with chronic hepatitis B.
Comparison of Ultrasound and MRI in Detecting Breast Cancer: A Retrospective Study in Mumbai Hospitals, India Singh, Rajendra; Aneel Kumar
Sriwijaya Journal of Radiology and Imaging Research Vol. 2 No. 2 (2024): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i1.120

Abstract

Introduction: Breast cancer is the most common cancer in women throughout the world. Early detection of breast cancer is very important to increase the chances of cure. Ultrasonography (USG) and magnetic resonance imaging (MRI) are two imaging methods commonly used to detect breast cancer. The aim of this study was to compare the accuracy of ultrasound and MRI in detecting breast cancer in female patients at Mumbai Hospital, India. Methods: A retrospective study was conducted on 2435 female patients who underwent ultrasound and MRI examinations at Mumbai Hospital, India between 2018 and 2023. Patient data was collected from electronic medical records and analyzed to compare the accuracy of ultrasound and MRI in detecting breast cancer. Results: The research results show that MRI is more accurate than ultrasound in detecting breast cancer. MRI sensitivity was 95.2%, while ultrasound sensitivity was 78.3%. The specificity of MRI was 98.7%, while the specificity of USG was 94.3%. The positive predictive value of MRI was 95.2%, while the positive predictive value of USG was 87.5%. The negative predictive value of MRI was 98.7%, while the negative predictive value of USG was 94.3%. Conclusion: MRI is recommended as the primary imaging method for detecting breast cancer in female patients. Ultrasound can be used as a complementary method to MRI.
Clinical and Radiological Assessment of Patients with Lung Cancer Using Chest CT Scan: An Observational Study in a Barcelona Hospital, Spain Banos, Stephanie
Sriwijaya Journal of Radiology and Imaging Research Vol. 2 No. 2 (2024): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i1.121

Abstract

Introduction: Lung cancer is one of the most common and deadliest types of cancer in the world. Chest CT scan is an important diagnostic tool for detecting and evaluating lung cancer. This study aimed to assess the clinical and radiological characteristics of patients with lung cancer who underwent chest CT scans at Barcelona Hospital, Spain. Methods: This research is a retrospective observational study involving 1059 patients diagnosed with lung cancer who underwent chest CT scans between 2018-2023. Patient data were collected from electronic medical records, including demographic information, clinical symptoms, CT scan findings, and histopathological diagnosis results. Results: The most common clinical symptom was cough (83.0%), followed by shortness of breath (58.8%), chest pain (45.6%), coughing up blood (20.3%), and weight loss (17, 9%). The most common CT scan finding was lung nodules (80.6%), followed by consolidation (39.7%) and pleural effusion (26.9%). The most common histopathologic diagnosis was adenocarcinoma (40.4%), followed by squamous cell carcinoma (29.5%), large cell carcinoma (17.9%), and neuroendocrine cell carcinoma (12.3%). Conclusion: This study provides an overview of the clinical and radiological characteristics of patients with lung cancer who underwent chest CT scans at the Barcelona Hospital, Spain. The findings of this study may help doctors in diagnosing and managing patients with lung cancer.
Effectiveness of MRI in Detecting and Diagnosing Brain Tumors in Children: A Meta-Analysis Hidayat, Rachmat
Sriwijaya Journal of Radiology and Imaging Research Vol. 2 No. 2 (2024): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i1.122

Abstract

Introduction: Brain tumors are one of the most common types of cancer in children. Accurate and timely diagnosis is essential to determine optimal treatment and improve patient prognosis. Magnetic resonance imaging (MRI) has become one of the main imaging modalities for detecting and diagnosing brain tumors in children. Methods: A meta-analysis was conducted to evaluate the effectiveness of MRI in detecting and diagnosing brain tumors in children. Twelve studies that met the inclusion criteria were evaluated for sensitivity, specificity, positive predictive value (NPV), negative predictive value (NPV), and positive likelihood ratio (LR+). Results: The results of the meta-analysis showed that MRI had a sensitivity of 92.5% (95% CI: 86.4% - 96.7%) and a specificity of 97.3% (95% CI: 94.2% - 99.0%) for detecting brain tumors in children. NPV and LRP+ were 97.0% (95% CI: 93.8% - 99.2%) and 33.1 (95% CI: 11.8 - 117.2), respectively. Conclusion: MRI is recommended as the imaging modality of choice for detecting and diagnosing brain tumors in children.
Evaluation of the Diagnostic Accuracy of PET/MRI in the Staging of Prostate Cancer: A Retrospective Study in Barcelona, Spain Guelle, Paula; Sandra Quinn
Sriwijaya Journal of Radiology and Imaging Research Vol. 3 No. 1 (2025): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i2.161

Abstract

Introduction: Accurate staging of prostate cancer (PCa) is crucial for treatment planning and prognostication. The integration of positron emission tomography (PET) and magnetic resonance imaging (MRI) into a single hybrid system (PET/MRI) has shown promise in improving PCa staging accuracy. This study aimed to evaluate the diagnostic accuracy of PET/MRI in the staging of PCa in a cohort of patients from Barcelona, Spain. Methods: A retrospective analysis was conducted on 120 patients with biopsy-proven PCa who underwent PET/MRI for staging between 2018 and 2023 at a tertiary care center in Barcelona. PET/MRI findings were compared with the histopathological results from radical prostatectomy or biopsy as the reference standard. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated for PET/MRI in detecting local tumor extent (T-stage), lymph node involvement (N-stage), and distant metastases (M-stage). Results: PET/MRI demonstrated a sensitivity of 92%, specificity of 88%, PPV of 90%, NPV of 91%, and accuracy of 90% for T-staging. For N-staging, the sensitivity, specificity, PPV, NPV, and accuracy were 85%, 94%, 82%, 95%, and 92%, respectively. In the detection of distant metastases (M-stage), PET/MRI showed a sensitivity of 90%, specificity of 98%, PPV of 95%, NPV of 96%, and accuracy of 97%. Conclusion: PET/MRI exhibits high diagnostic accuracy in the staging of PCa, particularly in the assessment of local tumor extent, lymph node involvement, and distant metastases. The integration of PET/MRI into clinical practice may improve the accuracy of PCa staging, leading to more personalized treatment decisions and improved patient outcomes.
Transarterial Chemoembolization for Hepatocellular Carcinoma: An Evaluation of Long-Term Outcomes in Beijing, China Xi Liang-Wu
Sriwijaya Journal of Radiology and Imaging Research Vol. 3 No. 1 (2025): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i2.162

Abstract

Introduction: Transarterial chemoembolization (TACE) is a widely used treatment for unresectable hepatocellular carcinoma (HCC). This study aimed to evaluate the long-term outcomes of TACE in a cohort of patients with HCC in Beijing, China. Methods: This retrospective cohort study included patients who underwent TACE for HCC at a tertiary care hospital in Beijing, China, between 2010 and 2018. Data on patient demographics, tumor characteristics, treatment details, and outcomes were collected from medical records. Overall survival (OS) and progression-free survival (PFS) were the primary endpoints. Survival analysis was performed using the Kaplan-Meier method and Cox proportional hazards regression. Results: A total of 352 patients were included in the study. The median follow-up duration was 48 months (range: 6-120 months). The median OS was 36 months, and the 5-year OS rate was 28%. The median PFS was 12 months, and the 3-year PFS rate was 15%. Tumor size, Barcelona Clinic Liver Cancer (BCLC) stage, and alpha-fetoprotein (AFP) level were independent predictors of OS and PFS. Conclusion: TACE can provide long-term survival benefits for patients with HCC in Beijing, China. Tumor size, BCLC stage, and AFP level are important prognostic factors for TACE outcomes.
Targeted Radionuclide Therapy for the Treatment of Metastatic Bone Disease: A Retrospective Analysis in Moscow, Russia Poppy Filmonov; Ayesh Mahmood
Sriwijaya Journal of Radiology and Imaging Research Vol. 3 No. 1 (2025): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i2.163

Abstract

Introduction: Metastatic bone disease (MBD) is a common complication of advanced cancer, causing significant morbidity and negatively impacting patients' quality of life. Targeted radionuclide therapy (TRT) has emerged as a promising treatment modality for MBD, offering targeted delivery of therapeutic radiation to bone metastases while minimizing damage to healthy tissues. Methods: A retrospective cohort study was conducted at leading oncology centers in Moscow, Russia, between 2018 and 2023. Patients with MBD who received TRT with either Strontium-89 or Samarium-153 were included. Data on patient demographics, primary tumor type, number of bone metastases, pre-treatment pain scores, performance status, and survival outcomes were collected. Results: A total of 150 patients were included in the study (mean age 62 years, 55% female). The most common primary tumor types were prostate (35%), breast (25%), and lung (15%). The median number of bone metastases was 5 (range 1-20). Pre-treatment pain scores were high (median 7 on a 0-10 scale). A significant reduction in pain scores was observed post-TRT (median 3, p<0.001). Overall survival at 1 year was 75%, with a median survival of 18 months. Favorable prognostic factors included a lower number of bone metastases, good performance status, and absence of visceral metastases. Conclusion: TRT is a safe and effective treatment option for patients with MBD in Moscow, Russia, offering significant pain palliation and improved quality of life.
Functional MRI for the Assessment of Brain Connectivity in Neurodegenerative Diseases: An Observational Study in Mexico City Rodriguez, Maria; Salazar Torres
Sriwijaya Journal of Radiology and Imaging Research Vol. 3 No. 1 (2025): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i2.164

Abstract

Introduction: Neurodegenerative diseases are characterized by progressive brain dysfunction and structural changes. Functional MRI (fMRI), a non-invasive imaging technique, offers the potential to assess brain connectivity and identify early biomarkers of these diseases. Methods: This observational study included patients with Alzheimer's disease (AD), Parkinson's disease (PD), and healthy controls in Mexico City. Resting-state fMRI data was acquired, and brain connectivity was analyzed using independent component analysis (ICA) and seed-based correlation analysis (SCA). Results: fMRI revealed altered brain connectivity patterns in AD and PD compared to healthy controls. In AD, decreased connectivity was observed within the default mode network (DMN), while PD patients showed reduced connectivity in the motor network. Conclusion: fMRI provides valuable insights into brain connectivity changes in neurodegenerative diseases. These findings contribute to the development of early diagnostic tools and potential therapeutic targets for AD and PD.
The Role of Ultrasound in the Diagnosis and Management of Pediatric Abdominal Emergencies in Jakarta, Indonesia Istiqomah Putri; Ratih Dwi Astuti
Sriwijaya Journal of Radiology and Imaging Research Vol. 3 No. 1 (2025): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v2i2.165

Abstract

Introduction: Pediatric abdominal emergencies demand swift and accurate diagnosis for optimal management. In resource-constrained settings, point-of-care ultrasound (POCUS) has emerged as a valuable tool. This study aimed to evaluate the utility of ultrasound in diagnosing and managing pediatric abdominal emergencies in Jakarta, Indonesia. Methods: A retrospective review of pediatric patients (age ≤ 18 years) presenting with acute abdominal pain to a tertiary care hospital in Jakarta from 2018 to 2023 was conducted. Data collected included demographics, clinical presentation, ultrasound findings, final diagnosis, and management decisions. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of ultrasound for various abdominal emergencies were calculated. Results: A total of 543 patients met the inclusion criteria. The most common diagnoses were appendicitis (n=187, 34.4%), intussusception (n=82, 15.1%), and gastroenteritis (n=75, 13.8%). Ultrasound demonstrated high sensitivity and specificity for diagnosing appendicitis (92% and 88%, respectively), intussusception (95% and 90%), and free fluid in the abdomen (98% and 94%). POCUS influenced management decisions in 68% of cases, including expediting surgery or avoiding unnecessary interventions. Conclusion: Ultrasound is a valuable tool for the diagnosis and management of pediatric abdominal emergencies in Jakarta. Its high sensitivity and specificity, coupled with its point-of-care availability, make it particularly useful in resource-limited settings.

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