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Contact Name
Mochamad Nashrullah
Contact Email
Nashrul.id@gmail.com
Phone
+6285745063538
Journal Mail Official
Nashrul.id@gmail.com
Editorial Address
Kavling banar, Pilang, Wonoayu, Sidoarjo
Location
Kab. sidoarjo,
Jawa timur
INDONESIA
JMGCB
Published by Antis Publisher
ISSN : -     EISSN : 30321085     DOI : https://doi.org/10.61796/jmgcb.v1i1
Core Subject : Health, Science,
The European Journal of Medical Genetics and Clinical Biology is a peer-reviewed journal that publishes articles in English on various aspects of human and medical genetics, the genetics of experimental models, and developmental anomalies. Original clinical and experimental research articles, short clinical reports and review articles are welcome on topics such as: Clinical genetics and genomics, including neurodevelopmental disorders and single or multiple malformations syndromes and dysmorphology; Inherited predisposition to cancer: rare inherited cancer predisposition syndromes and biology and pathophysiology of inherited cancers; Fetal medicine and prenatal diagnosis, including prenatal diagnosis, prenatal screening, fetal therapies and teratology; Diagnostic methods including sequencing studies (gene level), transcriptome studies, methylome and other Omics technologies, variant interpretation and functional validation; Bioinformatics and statistical methods in genetics; Personalized Medicine and therapies, including gene therapy and gene editing, non-genetic treatment of genetic disease, pharmacogenetics and genomics, theranostics and clinical trials; Molecular biology and pathophysiology of genetic and genomic diseases: biology of cell, pathways and systems, epigenetics and gene regulation, biology and pathophysiology of specific genes and non-coding DNA; Genetics and variants in populations: carrier screening, population genetics, evolutionary genetics, genetic epidemiology of diseases, genome variation and architecture in normal population;
Articles 223 Documents
Production of alpha-amylase enzyme from grain sprouting Saeed Khalif Salman; Ahmed Farhoud Ktub; Ali Taaman Nayef
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.424

Abstract

Alpha-amylase is considered to be one of the primary enzymes responsible for starch degradation in cereals. During grain germination, α-amylase initiates the conversion of starch into simple sugars to fuel embryo and coleoptile growth in the first few days of germination. The present study involves the estimation of Alpha amylase content in four different grains varieties, namely, wheat grain and barley up to 8 days after germination. It was observed that, alpha amylase content steadily increased, and found to be saturated after reaching the peak values. In all the samples, the peak values were observed in 7th day of germination. The enzymatic assay were done by estimation of maltose content by Spectrophotometry as starch degraded to maltose by alpha amylase enzyme.
ISOLATION OF BACTERIA CAUSING DENTAL CARIES FROM THE CLINICS OF THE COLLEGE OF BILAD AL-RAFIDAYN UNIVERSITY Ahmed Qasim Abdulmahdi; Dumoua Latif Haram; Rasha Hadi Hassoun; Layla Salal Maktof; Hussein Ali Jassim; Ali Hussain Abd Alamir; Haneen Jumaa Ajeel; Hussein Abdelhassan Talab; Zahraa Ali Naji
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.426

Abstract

This study deals with Isolation of bacteria causing dental caries from the Forty samples (male and female) were collected from patients attending the clinics of the Department of Dentistry at Bilad Al-Rafidayn University College for the period 7/11/2022 to 4/5/2023. The total of (58) isolates before and after cleaning and tooth extraction collected from male and female samples .After diagnosing these isolates, it was found that. Streptococcus (42.5%) and gram-negative (20%) before dental work and cleaning . The Percentage of Streptococcus after cleaning (30%) and the gram-negative rod (7.5%). The percentage of Streptococcus isolated from tooth extraction (20%) and staphylococcus (2.5%) and gram-negative rod(2.5%). The spacemen were collected from the oral cavity and the culture was on mitis salivarius(Himedia/India) agar base, that was determined by biochemical tests by use of blood agar to detect hemolysis, the results revealed the samples were positive.
STUDY OF THE PREVALENCE OF INTESTINAL PARASITIC INFECTIONS AMONG CHILDREN IN SHATRAH DISTRICT / THI-QAR PROVINCE - SOUTH OF IRAQ Amal F. AL-Gorani
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.427

Abstract

The current study aimed to determine the prevalence of intestinal parasites among children from newborns to ten years of age in different areas affiliated with the Shatra district in Dhi Qar Governorate in southern Iraq, as these areas suffer from poor health and living services in addition to a lack of awareness and interest in personal and health hygiene. The study was designed by taking 100 A random sample from different areas. The results were 25% of healthy children, while 75% were infected. The widespread infections were with the parasites Giardia lamblia and Entamoeba histolytica. The results confirmed that most of the infected children were between two and four years of age, in addition to the fact that the most common infections were the combined infections of the Entamoeba parasite and Giardia for the same infected people, with a very high rate of up to 56%, while the infection of children with the Entamoeba parasite alone was 18.7% and Giardia alone was 25.3% in addition. The percentage of females is 65% while the percentage of males is 35% in parasitic infections and The infection rate in the countryside was higher than the infection rate in cities, as the infection rate in the countryside was (55%) and in the cities (45%).
BIOLOGICAL PRODUCT - BIOINSECTICIDE Pulotov F.S; Sayfiddinov K.F
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.428

Abstract

In this article Bacillus thuringiensis var.thuringiensis on the bacterial strain thuringiensis Uzviti М №1, data are presented on the research work on the study of the insecticidal properties being carried out at the same time on the experimental series of the biological drug bioinsecticid, which was first prepared in a laboratory setting
THE SIGNIFICANCE OF ECHINOCOCCOSIS IN VETERINARY MEDICINE AND HUMAN LIFE Kamalova A.I.,
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.434

Abstract

This article provides information on the history, prevalence, veterinary and human significance of echinococcosis, as well as preventive measures.
Study Of Cows Of The Golshtin Breed By Comparing Generally Known Indicators During The Second Lactation Mirsaidova Zukhra Shukhrat daughter; Khujamov Zhurabek Nayimovich
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.448

Abstract

This article examines and compares the milk production of Holstein cows from Dutch, German, and Danish selection based on their constitution. The study focuses on milk yield, milk fat, milk protein yield, and 4% milk yield per 100 kg of live weight. Data was provided.
LEUKOCYTE VIRUS AND IMMUNOLOGICAL RESPONSE OF THE BODY Butaev Makhmud Qarshievich; Salimov Khait Salimovich; Ruziev Zohid Egamberdievich
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.449

Abstract

This study examined the immunological condition of cattle infected with spontaneous leukosis. Specifically, it compared the levels of immunoglobulins in cattle infected with leukosis viruses from three different genera to those in healthy cattle. The moles in the experiment were vaccinated against protein illness to artificially stimulate their immune response. Significant alterations were noted in IgG2, and it was discovered that the distinction between breeds was hindered
DIAGNOSIS OF INFECTIOUS NECROTIC HEPATITIS DISEASE Salimov Ilkhom Khaitovich; Hakimov Shorasul
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.450

Abstract

The article outlines laboratory techniques for diagnosing infectious necrotic hepatitis in sheep using pathological material. It also provides guidance on how to properly choose, package, and transmit the pathological material from deceased sheep to the laboratory. The process of isolating the causative agent of the disease and examining its cultural, morphological, and biological features. Additionally, a biological research method for studying this infection is also available
DETERMINATION OF THE EFFECTIVENESS AND USE OF SOME ANTHELMINTIC DRUGS IN THE TREATMENT OF FASCIOLOSIS IN GOATS Hazratqulov I.A; Usmanov I.G; Raximberganov B.Sh
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.451

Abstract

In this article, the effectiveness of the newest anthelmintic drugs in the treatment of fasciolosis in goats in the irrigated areas of Surkhandarya region was determined
Harnessing CRISPR-Cas for Targeted Epigenetic Manipulations: a physiological study of Gene Regulation Qammar Shaker Hmood
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 5 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i5.453

Abstract

Genome engineering, epigenome editing, as one of the prominent research techniques, has also become instrumental in discovering the gene expression regulation mechanisms and exploring their physiological correlates in health and pathology. This review summarizes the state-of-the-art CRISPR-Cas strategies that focus on epigenetics modification and projects its utility in molecular physiology of gene regulation. In this course we will delve into how CRISPR-Cas systems interact with epigenetic signals through DNA methylation, histone modifications and accessibility to chromatin. Then we look at the physiological effects of epigenetic modulations in cellular differentiation and development, cellular signal and homeostasis, disease pathogenesis, and therapeutic for application. Issues and perspectives on how epigenome manipulations can revolutionize therapeutics are also emphasized exploring the potential of precision medicine and individualized therapies. Overall, the review stresses the pivotal role of epigenetic modulation in the development of our understanding of gene expressions/mediation and cellular physiology. It also provides some inputs on the potential directions that the field of genetic engineering might take in the future.

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