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Journal for Technology and Science
Published by Antis Publisher
ISSN : -     EISSN : 30474337     DOI : https://doi.org/10.61796/ipteks.v1i1
Core Subject : Engineering,
Aerospace Engineering Automotive Engineering Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Electrical & Electronics Engineering
The Journal for Technology and Science published by Antis Publisher eISSN 3047-4337 is a scholarly journal that focuses on original research articles in natural science and technology relevant to industries and communities in developing countries. Released annually in March, August, and November, it is inclusive of scientists, researchers, educators, and scholars. The journals scope encompasses various topics addressing current challenges encountered by industries, governments, and communities in developing nations. With a commitment to advancing knowledge and fostering innovation, The Journal for Technology and Science welcomes submissions that contribute to the advancement of science, technology, and their applications in addressing societal needs and promoting sustainable development in emerging economies
Arjuna Subject : Teknik (semua kategori) - Teknik (Lain-Lain)
Articles 94 Documents
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INVESTIGATING THE ROLE OF FCER1A GENE (RS2251746) POLYMORPHISMS AND INTERLEUKIN-6 LEVELS IN ABORTION RISK AMONG WOMEN WITH BLOOD ALLERGIES Nawres Adnan Abdulameer; Ibtissem Ben Amara
Journal for Technology and Science Vol. 3 No. 4 (2026): Journal for Technology and Science
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ipteks.v3i4.587

Abstract

Objective: We examined the correlation between functional polymorphisms in the high-affinity IgE receptor alpha chain gene (FCER1A), serum interleukin-6 (IL-6) concentrations, and the risk of RSA. Method: This case-control research comprised 185 women with idiopathic recurrent pregnancy loss (≥2 successive pregnancy losses) and 190 ethnically matched controls who had successful pregnancies. Genotyping of FCER1A polymorphisms (rs2251746). Serum IL-6 concentrations were quantified using ELISA. Relationships among genotypes, IL-6 concentrations, and clinical attributes were examined. Results: The FCER1A rs2251746 T allele exhibited a significant association with heightened RSA risk (OR=2.37, 95% CI: 1.69-3.31, p<0.001). The heterozygous (CT) and homozygous (TT) genotypes gave a 2.40-fold and 4.80-fold higher risk, respectively. Serum IL-6 concentrations were markedly increased in RSA patients relative to controls (6.84±2.31 vs. 3.62±1.47 pg/mL, p<0.0015). Genotypes Rs2251746 exhibited a significant correlation with IL-6 levels, demonstrating a steady increase from CC to TT genotypes in both RSA patients (p<0.0019) and controls (p=0.0072). In RSA patients, the TT genotype correlated with an increased incidence of pregnancy losses (p=0.0063) and an earlier gestational age at loss (p=0.0012) relative to other genotypes. Novelty: This offers fresh insights into the immunogenetic foundation of RSA and may reveal potential targets for therapeutic intervention in at-risk women.
MOLECULAR IDENTIFICATION OF MICROSPORUM SPP. THAT CAUSES RINGWORM IN HUMAN AND SOME ANIMALS Laila Jasim Shaebth; Louhichi Nacim
Journal for Technology and Science Vol. 3 No. 4 (2026): Journal for Technology and Science
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ipteks.v3i4.588

Abstract

Objective: To molecularly identify and determine the prevalence of Microsporum species from clinical isolates of both human and animal populations. Method: A total of 427 isolates, comprising 248 from human populations and 179 from animal populations, were included in the study. The molecular identification of Microsporum species from the isolates was performed by conventional PCR using the Internal Transcribed Spacer (ITS) regions, followed by PCR-RFLP using the MvaI restriction enzyme. Results: In the present study, Microsporum canis was found to be the predominant species, responsible for causing dermatophytosis in both human populations, where it accounted for 58.9% (146/248) of the isolates, and animal populations, where it accounted for 82.1% (147/179) of the isolates. In the human population, the second most common species, after M. canis, were M. audouinii (22.2%), M. gypseum (12.5%), and M. ferrugineum (5.2%). In the animal populations, M. gypseum was found to account for 14.5%, with small percentages of M. nanum (2.2%). Novelty: The effectiveness of the PCR-RFLP method for species differentiation is evident from the results, where each species of Microsporum produced unique banding patterns. For instance, M. canis produced bands at 329bp, M. gypseum produced bands at 186bp, while M. audouinii produced bands at 125bp.
EXPANSION AND DIRECTION OF URBAN AREAS IN AL-DIWANIYAH CITY Sawsan A AL-Omrani; Hamsa Zubaidi
Journal for Technology and Science Vol. 3 No. 4 (2026): Journal for Technology and Science
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ipteks.v3i4.589

Abstract

Objective: Population growth and changes clearly impact any city's expansion and urban development, regardless of its natural and geographical characteristics. Despite the economic development and growth witnessed by Al-Diwaniyah after 2003, it suffers from many problems. Al-Diwaniyah experiences significant urban challenges, including traffic congestion, insufficient public services, the proliferation of informal settlements, and ongoing environmental degradation. The unregulated urban expansion has resulted in a significant increase in the built-up area over time, creating pressure on land use and existing infrastructure. Therefore, this study was conducted to determine the causes of these problems. Method: The use of Geographic Information Systems (GIS) was to explore the development in the urban areas to 2023, Results: the result shows that there is an expansion in the land used, as the area in 1958 was 1.5 03 km2, in 1972 the area reached 10.035 km2, while the area became 14.486 km2 in 2001, in 2008 the area became 17.4 38 km2. In 2014, the area increased to 26.1 111 km2, while the expansion of land use increased to 32.361 km2 in 2023, with expansion in the direction of the east of the city. This increase in land use is due to the population growth and economic growth in Iraq after the increase in oil revenues after 2003. Novelty: Among the most important reasons was that Diwaniyah is characterized by high population density and random expansion by encroaching on the lands adjacent to the city center.
EVALUATION OF NATURAL COUMARINS AS POTENTIAL INHIBITORS OF EFFLUX PUMP GENE EXPRESSION IN CARBAPENEM-RESISTANT ACINETOBACTER BAUMANNII FROM RESPIRATORY INFECTION PATIENTS Rami S. Owaid; Raghda S.M. Al-Omari; Masar J. Al-kurdy
Journal for Technology and Science Vol. 3 No. 4 (2026): Journal for Technology and Science
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ipteks.v3i4.590

Abstract

Objective: This study investigates the potential of natural coumarins to inhibit efflux pump gene expression in carbapenem-resistant strains of Acinetobacter baumannii isolated from respiratory infections. Carbapenem resistance is a growing public health threat, and A. baumannii is a notorious pathogen associated with nosocomial infections. Efflux pumps are one of the mechanisms bacteria employ to develop resistance by actively removing antibiotics from the cell. This study investigates the efficacy of coumarins against certain mechanisms of resistance in certain bacteria. Method: Microtiter plate dilution assays were used to determine the minimum inhibitory concentration (MIC) of the antibiotic meropenem, a member of the class of carbapenems, along with coumarins. The study started from January to June 2023, a total (100) sputum specimens were collected from the Intensive Care Units (ICUs) of hospitals in Diwaniyah. Carbapenem-resistant A. baumannii had four isolates used in the study, each of the six experimental groups. Group 1 was a control and was subjected to a sub-MIC (6.25 µg/mL) of the carbapenem active antibiotic. Group 2 was the control and was subjected to 50 µg/mL of ethidium bromide (EtBr) to confirm the presence of functional efflux pumps. Groups 3 to 6 investigated the interaction of coumarins at a sub-MIC (62.5, 125, 250, and 500 µg/mL) with meropenem. A unique experimental control was used in this study which was real-time quantitative PCR (qPCR) to measure the fold change and the relative expression of two efflux pump genes, adeR and adeB, in all groups. Statistical methods that used were Chi-square at (P < 0.01) and LSD in one way ANOVA method at (P< 0.05) as well as histograms analysis were performed by using GraphPad Prism 7 Statistics software for estimation the difference between means in all groups of the experiment were used. Results: Given both genes had the same fold change in the control group, that change was determined to be 1.0. The corresponding relative changes in control values of the coumarin groups were 0.06 to 0.32 for adeR and 0.25 to 0.66 for adeB which means that both groups in the study were highly over-expressing the genes, exhibiting at least a 2-fold increase in the baseline expression, while the other group (the control) was also exhibiting very high baseline expression. EtBr group’s increase was the most pronounced across the board and in tune with the most upregulation and the function of being an established efflux pump substrate. Statistical comparisons highlighted significant differences between ADEB gene expression in the sub-MIC control and all the coumarin treated groups. Interestingly, for the adeR gene, significant differences were observed only between the control and EtBr groups, not between the control and coumarin-treated groups themselves. Novelty: This study concludes that coumarin treatment at the tested concentrations significantly downregulates the expression of adeR and adeB efflux pump genes in carbapenem-resistant A. baumannii isolates. This downregulation potentially enhances the efficacy of meropenem against these multidrug-resistant bacteria.

Page 10 of 10 | Total Record : 94

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