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Trends in Infection and Global Health
Published by Universitas Syiah Kuala
ISSN : 2806646x     EISSN : 2806646x     DOI : https://doi.org/10.24815/tigh.v1i2.23580
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
TIGH publishes primary research papers, review articles, short communications and letters on the following topics: Tropical diseases Microbiology Epidemiology Public health Population health One Health Immunology Chronic diseases Surgical disease and surgical care Chemotherapy and pharmacology Maternal and child health Clinical tropical medicine
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol 1, No 2 (2021): December 2021" : 5 Documents clear
The pandemic of COVID-19 decreased adherence to treatment among hypertension patients at Dr. Zainoel Abidin Hospital Ghina Salsabila Rahman; Muhammad Ridwan; Hilwah Nora; Maimun Syukri; Fitri Dewi Ismida
Trends in Infection and Global Health Vol 1, No 2 (2021): December 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i2.22418

Abstract

Hypertension is one of the leading causes of mortality and morbidity worldwide. Treatment adherence is an essential factor in controlling blood pressure among hypertensive patients. This study aimed to evaluate the effect of the Coronavirus disease 2019 (COVID-19) pandemic on treatment adherence among hypertensive patients at Dr. Zainoel Abidin Hospital, Aceh, Indonesia, as well as to determine its associated factors. A cross-sectional study was conducted at the Cardiac Center by utilizing medical records of hypertensive patients visiting during the period of April-July 2019 and December 2020-March 2021. Bivariate analysis using the Kruskal-Wallis test was employed to examine the effect of the COVID-19 pandemic on patients’ adherence. The results showed that the number of patients adhering to treatment significantly decreased (p=0.000) by 22.7%, from 179 patients in 2019 to 64 patients in 2020. The data also suggested a significant positive association between residential and patient adherence before the pandemic (p=0.006); however, no significant difference was observed between residential and patients’ adherence after the pandemic (p=0.282). Furthermore, our study found no association between age and adherence before and after the pandemic (p=0.690 in 2019 and p=0.125 in 2020). In conclusion, the pandemic of COVID-19 significantly affected treatment adherence among patients with hypertension at Aceh provincial hospital, with a decreased number in patient visits up to 22.7%.  
Irrational use of azithromycin in typhoid endemic areas: A challenge on multidrug-resistant typhoid treatment Irfan Ullah; Kiran Shafiq Khan; Qasim Mehmood; Muhammad Junaid Tahir; Muhammad Irfan Malik; Ali Ahmed; Muhammad Usman Munir
Trends in Infection and Global Health Vol 1, No 2 (2021): December 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i2.23580

Abstract

Typhoid is a food-borne fatal disease caused by Salmonella typhi. It causes inflammation of the intestine, resulting in diarrhoea, fever, headache, cough, and muscle pain. Improved hygiene has resulted in a marked decline in typhoid fever cases in many developed countries. However, significant typhoid cases emerge in low and middle-income countries annually, including Pakistan. Typhoid fever accounts for a larger percentage of acute febrile illnesses in Pakistan. Azithromycin is the only effective drug used in multidrug-resistant typhoid. The emergence of drug resistance typhoid has been of more significant concern in recent years due to its irrational use of azithromycin. It is considered the last antibiotic to eradicate multidrug-resistant typhoid fever from Pakistan. In this article, we express our concern of the irrational use of azithromycin in Pakistan and its effect on typhoid in the country.
Coinciding SARS-CoV-2 infection in HIV patients with cerebral toxoplasma Dika Chandra Bintari; Paulus Sugianto
Trends in Infection and Global Health Vol 1, No 2 (2021): December 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i2.23478

Abstract

A massive and notorious impact of coronavirus disease 2019 (COVID-19) pandemic has affected communities worldwide, urging extra preventive measure, especially for individuals with comorbidities including those who are suffering from human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). We reported a case of a 45-year-old man with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and HIV infection as well as toxoplasmosis. The patient presented to the hospital with decreased consciousness and stiffness on both hands and feet accompanied with loss of appetite, fever, and coughing. Since 2014, he had been diagnosed with HIV and undergone combined antiretroviral therapies. Toxoplasmosis was revealed by multislice computed tomography (MSCT) showing multiple rim-like lesion in cortex-subcortex of left temporal lobe along with surrounding perifocal oedema. Furthermore, the finding was corroborated by the contrasted image exhibiting rim enhancement patterns. The patient was also RT-PCR confirmed Covid-19. Following examinations, the patient received pyrimethamine with a loading dose of 200 mg. The management was continued with oral intake of pyrimethamine, clindamycin, folic acid, and vitamin B6 for maintenance dose. This case report suggests that HIV patient suffering from COVID-19 can be treated with antiretroviral therapies since the specific antivirus for SARS-CoV-2 has not yet available. We believe that this case report could contribute to more understanding on the development of clinical management for COVID-19 in HIV-positive patients.
Chronic lymphocytic leukemia in a farmer and vegetable seller: Associated with exposure of multiple work-related hazards? Dewi S. Soemarko; firly ratsmita
Trends in Infection and Global Health Vol 1, No 2 (2021): December 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i2.21582

Abstract

There are several risk factors associated with the incidence of chronic lymphocytic leukaemia (CLL), namely genetic factors, smoking, and occupational exposure to chemicals. We highlight a possible association of a CLL case and the occupational. We reported a case of CLL patient, a 69-year-old man, who had been working as a vegetable seller and a chili farmer since 15 and 4 years ago, respectively. The patient was diagnosed with CLL three months prior to admission and had a history of three times blood transfusions. The patient only complained of paleness and weakness without any specific symptoms. No swelling of the lymph nodes, hepatomegaly, or splenomegaly was found. As a vegetable seller and chili farmer, the patient was exposed to five hazards, physical, chemical, biological, ergonomic to psychosocial. Therefore, it is necessary to analyse whether there was an association between the patient's work and the current CLL. To diagnose occupational diseases, several steps are needed. In this patient, one of the risk factors that could lead to CLL was exposure to chemicals such as pesticides. However, information regarding the content of pesticides used was unclear and there were no results obtained from pesticides biomarker examination that might cause the disease, making it difficult to establish a definitive diagnosis of work-related cause. The patient could be advised to have biomarkers of pesticide substances checked, which requires control of farmers and vegetable sellers who might have been exposed to pesticides. The control mechanism might be started from elimination, substitution, engineering, administration, and use of personal protective equipment. A control mechanism is necessary to prevent the entry of contaminants into the body, especially through inhalation, oral, and dermal pathways. It is recommended to examine for biomarkers of pesticides containing organophosphates, organochlorines, or carbamates to determine the chronic effects on the accumulation of these chemicals that might cause CLL.
Pregnancy in a patient with dilated cardiomyopathy (DCM) Aulia Mustika; Aruman Yudantho
Trends in Infection and Global Health Vol 1, No 2 (2021): December 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i2.23285

Abstract

Pregnancy in dilated cardiomyopathy (DCM) has an extremely high risk. However, DCM is usually asymptomatic at a young age. In pregnancy with DCM, it appears progressive and becomes symptomatic. and mimicking with peripartum cardiomyopathy (PPCM). We reported a case of a 23-year-old woman who was 20 weeks pregnant with her first child complained of chest palpitations and severe faintness. These progressive symptoms have happened and started during pregnancy. This case report suggests that physiological and emotional burdens are greater during pregnancy, especially for dilated cardiomyopathy (DCM) patients. This condition often leads to the progression of the DCM. The DCM often headways from the asymptomatic phase upturn to the symptomatic stage.

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