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INDONESIA
Indonesian Journal Health Science and Medicine
Published by Universitas Muhammadiyah Sidoarjo
ISSN : -     EISSN : 30638186     DOI : https://doi.org/10.21070/ijhsm
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health Veterinary
Focus: The Indonesian Journal on Health Science and Medicine (IJHSM) focus to advance the field of health science and medicine by publishing high-quality, peer-reviewed research articles, reviews, and case studies. Our journal serves as a platform for researchers, clinicians, and healthcare professionals to share innovative findings, critical insights, and emerging trends in the broad domain of health science and medicine. Scope: Clinical Research and Practice Studies on the diagnosis, treatment, and prevention of diseases. Clinical trials and evidence-based practices. Advances in medical technology and therapeutics. Public Health Epidemiology and health statistics. Health policy and management. Community health initiatives and health education. Biomedical Science Research on cellular and molecular biology. Genetics and genomics. Pharmacology and toxicology. Health Care Systems and Services Health care delivery and management. Quality improvement in health care services. Health economics and health informatics. Global Health Health issues affecting populations worldwide. International health regulations and practices. Global health governance and diplomacy. Health Promotion and Disease Prevention Lifestyle and behavioral interventions. Preventive medicine and early detection. Nutritional science and physical activity. Mental Health Research on mental health disorders and treatments. Psychological well-being and mental health promotion. Integration of mental health services in primary care. Innovations in Health Education and Training Medical and health science education methodologies. Training programs for health professionals. Continuing education and professional development.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 87 Documents
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Search results for , issue "Vol. 2 No. 1 (2025): July" : 87 Documents clear
Evaluation of Lipid Profile and Thyroid Hormones in Breast Cancer Women: Evaluasi Profil Lipid dan Hormon Tiroid pada Wanita Kanker Payudara Al-Husseinawi, Hadeel Ali Shamkhi; Mohammed, Anwar Shati; Kamil, Azhar Abdul adheem
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.34

Abstract

Background: Breast cancer is the foremost cause of cancer-related mortality among women globally and the second most prevalent cause of cancer death among women in the United States Aim of the Study: The study aimed to determine the association between lipid and thyroid dysregulation with breast cancer. Material and Method: A total of hundred individuals were participate in this case-control study (50 women had a breast cancer, and 50 women without disease as a control group). The study was done at Al-habobi Teaching Hospital during the period from February to June 2024. The parameters were evaluated by using Cobas 111 for biochemical tests and Cobas 411 for hormones. The Results: The study showed all level of lipid profile increased significantly in cancer patients than control group, with except the level of HDL decreased significantly in breast cancer patient. With regard thyroid hormones the study noted only the T4 decreased significantly in breast cancer patient than control group, while the other hormones not effected by disease. Conclusion: The present study concluded that lipid levels are significantly affected in women with breast cancer, while thyroid hormones are not affected by the disease Highlights: Breast cancer is a leading cause of global female mortality. Assess lipid and thyroid dysregulation association with breast cancer. Lipid levels significantly altered; thyroid hormones mostly unaffected in breast cancer. Keywords: Breast Cancer, Lipid Profile, Thyroid Hormones
Molecular Characterization of Proton-Pumping NADH Family in Hydatids Isolated From Cattle: Karakterisasi Molekuler Keluarga NADH Pemompa Proton pada Hidatid yang Diisolasi dari Sapi Challoob, Maysoon Khazail; AL-Asadi , Sarmad Awad Mozan
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.54

Abstract

Echinococcus granulosus mainly causes cystic echinococcosis and its energy from complex VI depends on NAD families. The study aimed to characterize and investigate these families in the E.granulosus G1 strain, as well as to genotype hydrophobic dehydrogenases. The results revealed the G1 strain has 21 subunits of proton-pumping NADH dehydrogenases distributed between the nuclear and mitochondrial genomes. Fifteen subunits (71.43%) were in the mitochondrial genome, and six subunits (28.57%) were in the nuclear genome. The hydrophobic NADI to NAD4L subunits were amplified using specifically designed primers and were 100% present in the protoscoleces and germinal layers of hydatids. They had 98.1-100% identities with their counterparts from the reference G1 strain. Phylogeny showed that hydrophobic subunits clustered with their counterparts in the G1 strain and were distant from their counterparts in G6 and G7 strains. The hydrophobic subunits were conserved between the protoscoleces and germinal layer of hydatids, as well as between individuals of the G1 strain. Additionally, all proton-pumping NADH dehydrogenases can be used in the diagnosis of the closely related strains G1 and G3. Highlights: granulosus G1 Strain: 21 NADH dehydrogenase subunits identified. Gene Location: 71.43% mitochondrial, 28.57% nuclear genomes. Diagnostic Use: Hydrophobic subunits differentiate G1/G3 strains from G6/G7. Keywords: E. granulosus, G1 strain, NADH family, hydatids, hydrophobic
The Prevalence of Dyslipidemia in Pediatric Obesity and its relation to Life Style of Obese Children: Prevalensi Dislipidemia pada Obesitas Anak dan Hubungannya dengan Gaya Hidup Anak Obesitas Altaan, Esraa Azzam; Alsarraf, Zahraa; Abow, Frdoos Hameed
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.63

Abstract

Background: Pediatric overweight contributes to adulthood obesity, leading to increased mortality and morbidity. There are a number of environmental and genetic factors that can have an effect on one's weight, including nutrition and physical activity. It is important to note that the prevalence of dyslipidemia in children and adolescents serves as a warning signal at both the individual and population levels. This is because having an excessive amount of body weight might lead to health concerns associated with dyslipidemia. Aim: To evaluate the prevalence of dyslipidemia and the relationship between metabolic health and dietary and physical activity habits in obese children and adolescents. Methodology: A cross-sectional and case control study was conducted on 62 children aged 4-14 years at Ibn-Sena Taching Hospital and and Alwafaa center for endocrine and diabetes mellitus from 1st February 2024 to 1st November 2024. The sample consisted of 22 obese children and 40 normal weight children without dyslipidemia. Data was collected through questionnaires, height, weight, BMI, waist circumference, and blood samples. Independent t-test and Fisher Exact test. Results: The study revealed that obese children have a mean age of 10.97 years, higher cholesterol, triglyceride, and LDL levels, and lower HDL levels. Only 4 of these children with higher waist circumference and BMI had dyslipidemia, a prevalence of 18.2%. These children had a family history of obesity. Playing video game was 75.0% in dyslipidemic obese children, and no significant differences was found in snacks. Conclusion: Children with a BMI over normal were frequently affected by dyslipidemia. Children with dyslipidemia were older and had elevated fundamental anthropometric measurements, such as waist circumference and BMI, compared to overweight and obese children without lipid abnormalities. Highlights: ediatric obesity links to adult dyslipidemia, morbidity, and genetic factors. Cross-sectional study of 62 children; BMI, waist, and lipid tests. Dyslipidemia in 18.2% obese children; high BMI, cholesterol, triglycerides. Keywords: Dyslipidemia, Life style , Pediatric obesity, Prevalence
Bacteria Isolated From Respiratory Tract and Abscesses in Livestock: Bakteri yang Diisolasi dari Saluran Pernafasan dan Abses pada Ternak Dawoud, Salma Abd Al-Hussein; Abbas , Ismail Juma
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.76

Abstract

This research aims to identify the types of bacteria that have been isolated from various body fluids, including the abscess secretions and nasal secretions of sheep and cows. Cotton swabs were used togather isolates from animals suffering from respiratory ailments and abscesses. The specimens were subsequently transferred to the microbiological laboratory. They were cultured on blood agar media and incubated for a duration of 24 to 48 hours at a temperature of 37°C. Following the purification of the samples, traditional diagnostic methods, including biochemical tests, were conducted. Polymerase chain reaction, Its foundation is the utilization of the 16SrRNA gene which depends genetic material to diagnose bacteria .The 16SrRNA gene, found in all bacterial species, contains nine heterogeneous regions that facilitate the identification of various types of bacteria.. The sequence of the samples is then compared with the sequence found in GenBank, each bacteria has an international number by which it can be identified. The results of isolates obtained from the nasal secretions is Acinetobacter baumannii and from abscess secretions is Staphylococcus agnetis The study revealed that rare specimens were obtained and registered in the gene bank bearing the following numbers , PP809047.1 , PP809049.1. The results of the study also confirmed that some isolates, especially bacteria, are pathogenic and pose a danger to animals, but when transmitted to humans, they are deadly due to their opportunistic nature. Highlights: Bacteria isolated from sheep and cow secretions: Acinetobacter baumannii, Staphylococcus agnetis. Diagnostic methods: blood agar, biochemical tests, PCR using 16SrRNA gene. Rare specimens registered in GenBank, potentially pathogenic to animals and humans. Keywords: Respiratory tract infection , Body fluids ,Livestock.
MrKD Gene in Environmental Isolates of Biofilm Producing Klebsiella Pneumoniae: Gen MrKD pada Isolat Lingkungan Penghasil Biofilm Klebsiella pneumoniae Hamady, Sabah Raheem; Abas, Ismaal Jmia
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.77

Abstract

Biofilm This concept includes cell aggregates that are not attached to an interface but share traits with biofilms, such as flocs (floating biofilms) and sludge.K. pneumonia is a member of the Enterobactericeae family and is Gram-negative, non-motile, facultatively anaerobic, lactose fermentation, and is present in the environment in places like soil, vegetation, and water. It is also easily isolated from the mucosal surfaces of mammals. K. pneumoniae has at least two variants of type 3 fimbriae, with the most diversified form being the mrkD gene. Materials and Methods: Biochemical and Api20E assays were used to identify K. pneumoniae isolated from different environmental samples in Basra Governorate, Iraq, from 1/11/2021 to 1/1/2022. The Kirby-Bauer assay was performed, and biofilm phenotype formation was evaluated. Finally, the mrkD gene was detected by the PCR method. Results: results showed that the number of K.pneumoniae bacteria was 23 out of 122 samples, and then it was revealed that its ability to form biofilm was used in this study, where the two methods of Congo red were used. The presence of the mrkD gene, which is thought to be responsible for biofilm production, was investigated using a polymerase chain reaction device, and the mrkD gene was found in 34.78% of the samples. Conclusion: This research highlights that the presence of the mrkD gene in K.pneumoniae bacteria, which was isolated from different environmental samples, has a relationship with biofilm formation and shows the extent of biofilm resistance to antibiotics Highlights: Biofilm & K. pneumoniae: Forms biofilms, contains mrkD gene, resists antibiotics. Methods: Identified via biochemical tests, Kirby-Bauer assay, and PCR analysis. Results: 34.78% of isolates carried mrkD gene, linked to biofilm formation.. Keywords: Klebsiella pneumoniae, biofilms, mrkD gene.
Influence of Food Quality and Quantity on Cannibalistic Behavior in Tribolium Castaneum Adults Towards Larvae and Their Attraction to Preferred Food Sources: Pengaruh Kualitas dan Kuantitas Makanan terhadap Perilaku Kanibalisme pada Tribolium Castaneum Dewasa terhadap Larva dan Ketertarikannya pada Sumber Makanan yang Disukai Khudhier, Hasnaa Talib; Jawad, Huda Noori; Jabbar, Hussain Ali
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.78

Abstract

The current study aims to scrutinize the qualitative and quantitative impacts of three essential food types which are wheat flour, dry milk, and mays starch on the cannibalism process of the adult Tribolium castaneum and their larvae, and to identify the food type that is preferable for trapping and attracting adults during different periods of time. The results of the main effects showed that there are significant differences between the three food types in regard to their impact on the average survival rate. The average of surviving larvae is ranged from 9.3 larvae for wheat flour to 2.6 and 2.3 larvae for dry milk and mays starch treatments, respectively. The highest larval survival was at a concentration of 5 grams of wheat flour, while the lowest survival appeared to be at a concentration of 0.2 grams of dry milk and mays starch. During the first week, the highest number of surviving larvae was recorded, whereas the lowest one was observed in the fourth week; the survival rates were 7.0 and 2.0 respectively. In respect with the findings of the trapping and attraction of adult insects, wheat flour appeared to be the most attractive food type for adults, with an average of 50.2 insects if compared to 5.0 and 2.7 insects for dry milk and mays starch treatments, respectively. As for the average effect of time periods, the highest attraction took place on day five, with an average of 25.7 insects, while the lowest was recorded on day one, with an average of 10.6 insects. It was noticed that there was variation of the interaction effect; the highest average was observed on day five, while wheat flour treatment attracted 70.3 insects. On the contrary, the lowest effect for mays starch and dry milk treatments were recorded on the 4th and 5th days, with only an average of 2.5 insects attracted. Such findings highlight the significance of food type and food quantity in modifying predation behavior and adult attraction of Tribolium castaneum. Highlights: Survival: Wheat flour supports highest larval survival; dry milk and starch lowest. Attraction: Wheat flour attracts most adults, peaking at 70.3 insects on day five. Impact: Food type and quantity influence predation and adult attraction behavior. Keywords: E Cannibalism, Tribolium castaneum, Flour condition.
Study of Biologically Active Compounds and Inhibitory Activity of Bay Leaves Laurus nobilis L.: Studi Senyawa Aktif Biologis dan Aktivitas Penghambatan Daun Salam Laurus nobilis L. Ali, Zainab A.; Musa, Raghad Saad Al; Ethafa, Esraa S.; Hannosh, Widad S.
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.79

Abstract

The global demand for medicinal plants has increased recently as food source for functional, healthy and sensory properties. This study allows the identification of active compounds found in alcoholic bay leaf extracts by GC-MS technique that give the plant functional properties. The inhibitory activity of extracts at concentrations of 0.25, 0.50, 0.75 and 1 mg/ml were tested against four types of bacteria: Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa. The results found the emergence of a number of active compounds, volatile oils and flavor compounds with a retention time (RT) ranging between 4.861-40.551 minutes, including compounds that gave the highest area of 24.96% such as Eucalyptol and alpha.-Terpinyl acetate compound by Area 10.87%. The results also showed that S. aureus recorded the highest inhibitory diameter at a concentration of 1 mg / ml was 10.7 mm, while E. coli recorded the lowest inhibitory diameter compared to the rest bacteria at the same concentration was 9.5 mm. B. cereus and P. aeruginosa, showed the highest inhibitory diameter were 10.4 and 9.8 mm at a concentration of 1 mg / ml. Which indicates the possibility of introducing bay leaves in many diets, improving its health and functional properties and prolonging the storage period due to rich in biologically active compounds Highlights: Active Compounds Identified: Eucalyptol (24.96%), α-Terpinyl Acetate (10.87%) via GC-MS. Antibacterial Activity: S. aureus (10.7 mm), E. coli (9.5 mm) at 1 mg/ml. Potential Applications: Functional food ingredient, health benefits, extended shelf life.. Keywords: active compounds, Bay leaves, GC-MS, extracts, Laurus nobilis L
Evaluation of The Effect of Aqueous Garlic Extract Against Candida Albicans and Candida Krusei Isolated From The Vagina: Evaluasi Pengaruh Ekstrak Bawang Putih Berair Terhadap Candida Albicans dan Candida Krusei yang Diisolasi Dari Vagina Abdullah, Afrah Talib; Al-Hawash , Adnan B.; Dhari, Furdos Mashari
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.80

Abstract

The research sought to identify a plant-based antifungal alternative that demonstrates an anti-candida effect. The study focused on isolating and identifying vaginal candida while also testing garlic aqueous extracts for their effectiveness against the pathogenesis of Candida infections. Twenty Candida isolates were collected from 25 vaginal swabs taken at private clinics. The diagnostic results indicated a 60% infection rate for Candida albicans and 40% for Candida krusei. The garlic aqueous extracts demonstrated varying levels of inhibition that rose with higher concentrations (100, 500, 1000 µg/ml), with the maximum inhibition diameter observed at 1000 µg/ml, measuring 33mm for C. albicans and 29mm for C. krusei. The inhibitory effective concentrations of the aqueous extracts were similar to those of widely used antifungals (fluconazole and nystatin). Highlights: Identified Candida albicans (60%) and Candida krusei (40%) from vaginal swabs. Garlic aqueous extract showed dose-dependent antifungal activity against Candida species. 1000 µg/ml extract had inhibition comparable to fluconazole and nystatin. Keywords: Aqueous garlic extract, vaginal candida, antifungal
External Parasites of Acanthopagrus Latus in Bahr Al-Najaf, Iraq: Parasit Eksternal Acanthopagrus Latus di Bahr Al-Najaf, Irak Kareef, Haki Abdulabas Issa
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.94

Abstract

Abstract. 112 shank fish (Acamthopagruslatus) from Bahr Al-Najaf water in ALNajaf province were examined. 15.1% was the overall percentage of external parasite infection and intensity. Tetrahymenapyriformis infection rate was 3.5%, Chloromyxumdubinm infection rate was 12.5% with intensity 4.0, Argulus foliacus infection rate was 14.2% with intensity 3.4, and Ergassilusmosulens 9.8% with intensity 4.2. The percentage of infections with the parasites under investigation varied by month.   Highlights: Parasite Diversity: Four external parasite species were identified in Acanthopagrus latus, affecting different body parts. Monthly Variations: Infection rates fluctuated across months, with environmental factors likely influencing prevalence. Statistical Analysis: No significant monthly differences in infection rates were found, suggesting stable environmental or host-parasite dynamics.
Assessment of Cardiac Effect of Preeclampsia. Right Ventricular Function Analysis Using Speckle Tracking Echocardiography: Penilaian Efek Jantung dari Preeklampsia. Analisis Fungsi Ventrikel Kanan Menggunakan Ekokardiografi Pelacakan Spekel AL- Muhana , Manal Yahya I.; Dujeli , Amina A B AL
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.95

Abstract

Introduction, Preeclampsia is a hypertensive disorder of pregnancy that has significant implications for cardiac function, particularly on the right ventricle (RV). Research has shown that speckle tracking echocardiography (STE) is a valuable tool in evaluating subtle RV dysfunction that might not be detected by traditional methods. Method: Pregnant ladies with preeclampsia (n= 50) compare to normotensive pregnant women (n= 50) regarded as control. Echocardiography done for them by speckle tracking to evaluate function of right ventricle. Result: There was significant difference in right ventricular function, in right ventricular longitudinal strain from normotensive pregnant women by speckle tracking echo cardio graph (-16.1±2.05 vs -17.3±1.9). Conclusion: Hypertensive disease of pregnancy including preeclampsia affect the myocardial performance, this can be diagnosed by decrease in global longitudinal strain of right ventricle by speckle tracking echocardiography. Highlights: Preeclampsia affects right ventricular function, detectable via speckle tracking echocardiography. Compared 50 preeclamptic and 50 normotensive pregnant women using echocardiography. Reduced right ventricular longitudinal strain in preeclampsia (-16.1±2.05 vs -17.3±1.9). Keywords: preeclampsia, speckle tracking echocardiography, right ventricle, global longitudinal strain

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