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INDONESIA
Atom Indonesia Journal
Published by Badan Tenaga Nuklir Nasional
ISSN : -     EISSN : -     DOI : -
Core Subject : Science,
Materials Science & Nanotechnology
Exist for publishing the results of research and development in nuclear science and technology Starting for 2010 Atom Indonesia published three times a year in April, August, and December The scope of this journal covers experimental and analytical research in all areas of nuclear science and technology. including nuclear physics, reactor physics, radioactive waste treatment, fuel element development, radioisotopes and radio pharmaceutical engineering, nuclear and radiation safety, neutron scattering, material science and technology, as well as utilization of isotopes and radiation in agriculture, industry, health and environment.
Arjuna Subject : -
Articles 452 Documents
 19   20   21   22   23 
Radiolabeling Technique of Silver Nanoparticles (AgNPs) with Iodine-131 Radionuclide U.N. Sholikhah; R.R. Syahdi; S.E. Permatasari; E. Sarmini; S Sriyono; T. Widyaningrum
Atom Indonesia Vol 46, No 2 (2020): August 2020
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2020.745

Abstract

 Radiotherapy is an effective cancer therapy, where a certain dose of radiation is aimed specifically at target and is unaffecting to normal tissue. A selectiveradionuclide must be attached to the specific targeted organ. In this research, silver nanoparticles (AgNPs) were labeled with radionuclide of iodine-131 (131I) to be used in radiotherapy. Silver nanoparticles were synthesized using silver nitrate 0.0005 M, sodium borohydride 0.002 M, polyvinylpyrrolidone 0.3 % (w/v) and natrium chloride 1.5 M, and then followed by purification by centrifugation. Characterization was carried out with UV-Vis spectrophotometer, transmission electron microscope, particle size analyzer, and zeta-sizer. The results show that the maximum absorbance is on a wavelength of 398 nm, spherical shape with a diameter of 10 nm, polydispersity index of 0.455, and zeta potential value of –8 mV. The radiolabeling was done by adding sodium iodide-131 which had been oxidized by chloramine-T and immobilized in AgNPs colloidal solution, and the activity was then measured using a dose calibrator. The identification of radionuclide showed that the sample was free of impurities. The optimum system of radiochemical purity was obtained using Whatman 1 paper strip as the stationary phase and a mixture of methanol: water: ammonium acetate (1:1:1) as the mobile phase, which gave 96 % purity. This method is suitable for radiolabeling AgNPs with 131I to be used for radiotherapy.
Molecular and in silico Study of TP53 Codon 72 Polymorphism (rs1042522) in a Population Exposed to High Background Radiation in Mamuju-West Sulawesi D. Tetriana; S. Purnami; T. Rahardjo; W. Mailana; S. Nurhayati; E. Pudjadi; S. Tri Widyaningtyas; T. Ishida; D. Ramadhani
Atom Indonesia Vol 46, No 3 (2020): December 2020
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2020.984

Abstract

The evaluation of the tumor protein p53 (TP53) codon 72 polymorphism (rs1042522) status in a population exposed to high background radiation was performed in this study. Real-time polymerase chain reaction (Q-PCR) was used to genotype the rs1042522 polymorphism in 100 subjects from Takandeang, Salleto, and Ahu villages in Mamuju district, West Sulawesi. An in silico study was then conducted to identify the potential effects of the proline substitution associated with this polymorphism on protein stability. The in silico analysis was performed using three different computational tools, namely I-Mutant Suite, iStable, and Protein Variation Effect Analyzer (PROVEAN). Secondary and three-dimensional (3D) structural models for wild-type (WT) and variant TP53 were generated to predict potential structural changes in the protein. Electrostatic surface charge calculations were also performed to identify changes in the electrostatic charge of codon 72. The Pro72 and Arg72 frequencies among the inhabitants in the Takandeang, Salleto, and Ahu villages, who are Mandarese Austronesian-speaking ethnic group members, were 0.56 and 0.44, respectively. The in silico analysis revealed no negative effects on protein stability due to the proline substitution at codon 72, although molecular modeling showed several differences in the secondary and 3D structures of the TP53 variant compared with the structure of WT TP53. To determine the impact of the proline-coding allele on individual sensitivity to radiation exposure, we compared the micronucleus (MN) frequencies of each genotype. The results showed that the MN frequencies in individuals harboring the proline-coding allele were not significantly higher than those expressing the arginine-coding allele. In conclusion, this study revealed that the proline-coding allele for codon 72 of the TP53 gene represented the predominant genotype among Takandeang, Salleto, and Ahu villages inhabitants. The present study also demonstrated that individuals who carried the proline-coding allele were not more sensitive to radiation compared with those expressing the arginine-coding allele for codon 72 of the TP53 gene.
Cover Atom Indonesia Vol 47 No 1 cover47 cover47
Atom Indonesia Vol 47, No 1 (2021): April 2021
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2021.1142

Abstract

The Use of Image Processing and Analysis in Automated Biological Dosimetry D. Ramadhani; M. Syaifudin; S. Purnami; A. Naroeni
Atom Indonesia Vol 46, No 3 (2020): December 2020
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2020.960

Abstract

Biological dosimetry based on cytogenetic markers such as dicentric chromosome (DC) and micronuclei (MN) is, until now, the most frequently used method to estimate the radiation dose in the radiological accident event. Another biomarker that recently gains popularity in biodosimetry is γH2AX. All these three assays are microscope-based biodosimetry techniques, and therefore need manual scoring to estimate the radiation dose. Unfortunately, the manual scoring of these assays is time-consuming and labor-intensive. In the case of a large-scale radiological accident when many people are exposed to radiation, it is very useful to use image processing and analysis in the scoring process to obtain a faster result. Several commercial systems or open-source image processing software packages already developed automated scoring of DC, MN, and γH2AX assays. This article describes how image processing and analysis were applied in automated biodosimetry based on the DC, MN, and γH2AX assays.
Safety Investigation of Hazardous Materials Released from the Combined High Temperature Gas Cooled Reactor – Hydrogen Production Plant Using ALOHA Software D. Priambodo; S Sunarko; W. W. Purwanto
Atom Indonesia Vol 47, No 1 (2021): April 2021
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2021.939

Abstract

Safety Investigation of Hazardous Materials Released from The Combined High Temperature Gas Cooled Reactor (HTGR) – Hydrogen Production Plant Using ALOHA software has been carried out. Currently, most of studies for HTGR-hydrogen plant are focused only on the impact of hydrogen presence to the HTGR plant safety. Therefore, the objective of this study was to investigate the effect of the presence of natural gas and synthetic gas from Steam Methane Reforming hydrogen plant on the combine HTGR-Hydrogen production system using ALOHA software. Three selected hazardous materials: CH4, CO and H2 were analyzed. The selected potential hazards of the hazardous materials after leaking from the pipe were downwind suffocation/toxication, flammable area and blast area from vapor cloud explosion. Two types of parameter, i.e., meteorological dispersion (including wind speed, temperature, humidity, nuclear building air changes for day and night) and source release parameters (including pipeline length, and distance from the reactor building to the hydrogen plant), were selected for this study. The effects of the parameters on the hazard distance were then analyzed. The study shows that hydrogen detector needs to be installed at the plant to ensure safety of field operator. Furthermore, CO adsorber and H2 recombiner should be installed at the Reactor HVAC system for CO poisoning and H2 fire protection. Provision of a separation distance of more than 250 meters or construction of a blast barrier between the reactor building and the hydrogen plant is also recommended to protect the reactor from H2 explosion hazard.
Characterization of Fe-Chitosan-Succinate- NN’-Methylene Bis-Acrylamide as Ion Imprinted Polymer M. Suhartini; S. Anwar; A. Saefumillah; S. Prayitno; S Sudirman
Atom Indonesia Vol 46, No 2 (2020): August 2020
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2020.869

Abstract

High level of phosphate in the aquatic environment can reduce the amount of dissolved oxygen in the water which is harmful to the preservation of aquatic ecosystems. However, ion-imprinted polymer (IIP) is available to adsorp tripolyphosphate (TPP). In this study, Fe (III)-chitosan-succinate-tripolyphosphate complex was synthesized with NN’-Methylene Bis-Acrylamide (MBA) as a crosslinking  agent and gamma-ray as reaction initiator. The aim of the study is to observe the physical and chemical characteristics of radiation-induced crosslinking of IIP in the present of MBA. The results show that tripolyphosphate ion adsorption capacity on the Fe-chitosan-succinate-MBA ion-imprinted polymer improved by 75.62 % than that of the non-imprinted polymer.The Differential Scanning Calorimetry (DSC) analysis shows a significant difference in the endothermic, exothermic and glass transitions of chitosan, chitosan-succinate when compared to their complex salts. The Fourier Transform Infra-Red (FTIR)  analysis shows the presence of tripolyphosphate groups bonded by Fe-Chitosan-succinate-MBA ion imprinted polymer. Scanning Electron Microscope (SEM) analysis of IIP exhibits a significantly difference surface shapes between IIP with template still within the polymer matrix and after removal.
Radon Concentrations in Canned Liquid Juice A. A. Abojassim
Atom Indonesia Vol 47, No 1 (2021): April 2021
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2020.1030

Abstract

This study was performed at University of  Kufa, Iraq, using canned liquid juice samples found in Iraqi markets due to the absence of environmental contamination from radionuclides emitting 222Rn concentrations using RAD-7 detectors. The annual effective dose (AED) of 222Rn was estimated for children and adults from the ingestion of canned liquid juice samples. The estimated concentrations of 222Rn in unit (mBq/L) ranged from 35.4 to 249.1, with an average of  77.880.24 ± 15.42. It also shows that the AED values for children and adults in (nSv/y) ranged from 19.11 to 134.48 with an average of 43.31 ± 8.32 and from 22.67 to 159.55 with an average of 51.39 ± 9.88, respectively. All estimated results of 222Rn concentrations for juice samples were lower than the natural limits provided by the WHO and the European Union Commission to the public (0.5 and  1 Bq/L, respectively). Therefore, there are no health hazards from drinking juice sold in Iraq markets.
Construction and Evaluation of a Multipurpose Performance Check Phantom for Computed Tomography L.E. Lubis; I. Hariyati; D. Ryangga; I.A.S. Mu'minah; T. Mart; D.S. Soejoko
Atom Indonesia Vol 46, No 2 (2020): August 2020
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2020.1004

Abstract

The use of computed tomography (CT) has become a common practice in medical diagnosis in Indonesia. Its number, however, is not matched by the availability of dedicated-performance-check phantoms. This paper aims to describe the design, construction, and evaluation of an in-house phantom for CT performance check that accommodates both radiation dose measurement and image quality performance checks. The phantom is designed as laser-cut polymethyl methacrylate (PMMA) slabs glued together to form a standard cylindrical shape, with spaces to place dose measurement and image quality modules. In this paper, measurement results on both aspects are discussed and compared with standard phantoms and other works. For dose measurement, the constructed phantom exhibited the greatest absolute discrepancy against the reference standard phantom of 8.89 %. Measurement of the CT number linearity and modulation transfer function (MTF) yielded, at most, 7.51 % and 5.07 % discrepancies against Catphan 604, respectively. Meanwhile, although found to be more linear in the phantom-based contrast linearity test, the use of the in-house phantom for clinical image contrast threshold determination requires further study. For noise power spectrum (NPS) measurement, accurate results were obtained within a limited range of spatial frequency.
Finite-Difference Time-Domain Simulations of Radon Transport in Porous Media A. Tayebi; H. Bezzout; M. El Maghraoui; H. El Faylali
Atom Indonesia Vol 46, No 3 (2020): December 2020
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2020.902

Abstract

In this work, an efficient algorithm, using a finite-difference time-domain (FDTD) technique, is proposed for modeling the variation of radon concentration as a function of soil structure parameters and vice versa. The development of the FDTD model is based on the simultaneous resolution of the radon transport equation in a porous, homogeneous medium, namely the soil. This equation describes the concentration of radon per pore volume unit. The numerical results are compared with those of the literature or with the theoretical ones.
Preface Atom Indonesia Vol 47 No 1 preface471 preface471
Atom Indonesia Vol 47, No 1 (2021): April 2021
Publisher : PPIKSN-BATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/aij.2021.1143

Abstract

Page 21 of 46 | Total Record : 452

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