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Jurnal Kedokteran Brawijaya
Published by Universitas Brawijaya
ISSN : 02169347     EISSN : 23380772     DOI : http://dx.doi.org/10.21776/ub.jkb
Core Subject : Health,
Medicine & Pharmacology
JKB contains articles from research that focus on basic medicine, clinical medicine, epidemiology, and preventive medicine (social medicine).
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 14 Documents
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Search results for , issue "Vol. 32 No. 1 (2022)" : 14 Documents clear
Relationship between Nutritional Status, Frailty, and Cognitive Function among Elderly at Dr. H. Moch. Ansari Saleh General Hospital Banjarmasin Wiwit Agung Sri Nur Cahyawati; Roselina Panghiyangani; Muhammad Syauqi Abid Muslim; Novia Belinda Rahman
Jurnal Kedokteran Brawijaya Vol. 32 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.01.10

Abstract

The elderly often have nutritional problems. The risk of malnutrition can stimulate the prevalence of frailty and declining cognitive function in the elderly. The study aimed to analyze the relationship between nutritional status, frailty, and cognitive function in the elderly at Dr. H. Moch. Ansari Saleh Hospital Banjarmasin. This study was analytic observational using a cross-sectional method. A sample of 93 elderly was obtained using a total sampling technique according to the inclusion and exclusion criteria. The nutritional status assessment was done using the Mini Nutritional Assessment-Short Form (MNA-SF), the Edmonton Frailty Scale (EFS), and the Mini-Mental State Examination (MMSE). The results showed that the mean of Mini Nutritional Assessment score was 12.00±2.126, the average frailty score was 4.41±1.872, and the average value of cognitive function was 25.98±2.923. Data were analyzed using the Spearman's non-parametric correlation test with a 95% confidence level. The correlation test results between nutritional status and frailty obtained p=0.000 and r=-0.490. The correlation test results between nutritional status and cognitive function obtained p=0.000 and r=0.595. In short, there is a relationship between nutritional status on frailty and cognitive function in the elderly at Dr. H. Moch. Ansari Saleh General Hospital Banjarmasin, it means that the good nutritional status in the elderly, the risk of frailty syndrome will decrease and improve cognitive function.
Effectiveness of Hyaluronic Acid Nasal Drops in Post Functional Endoscopic Sinus Surgery Dian Yusnita; Anna Mailasari Kusuma Dewi; Riece Hariyati
Jurnal Kedokteran Brawijaya Vol. 32 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.01.5

Abstract

Functional Endoscopic Sinus Surgery (FESS) is commonly performed on patients with chronic rhinosinusitis (CRS) that has not improved through medical treatment. Hyaluronic acid (HA) has a vital role in wound healing and mucosa repair. This study aimed to determine the effectiveness of nasal drops using HA on clinical symptom scores, quality of life, and endoscopic features in post-FESS patients. This study was conducted with a pre- and post-test randomized control group design in 50 CRS patients undergoing FESS (25 males, 25 females, aged 18 to 55 years) at Dr. Kariadi General Hospital Medical Center Semarang from May to November 2019. The treatment group received additional HA therapy, while the control group only received standard therapy. Subjects were assessed with clinical symptom scores, quality of life, and endoscopic features before and after treatment. The statistical analysis was performed between the control and treatment groups using the Mann-Whitney test. There were significant differences between the control and treatment groups on clinical symptom scores (nasal congestion p = 0.001, runny nose p = 0.027) and endoscopic features (edema p = 0.001, secret p = 0.001, crusts p = 0.001). The therapy in post-FESS patients was using nasal drops, the treatment group was given HA, and the control group was given a placebo. Nasal drops using HA in the treatment group show improvement in clinical symptom scores of nasal congestion and runny nose, as well as the endoscopic appearance of edema, secret, and crusts.
Relationship of Depression and Sleep Quality among North Jakarta Medical Students during the COVID-19 Pandemic Annabella Naida Tanusetiawan; Surilena Surilena; Nelly Tina Widjaja; Dharmady Agus
Jurnal Kedokteran Brawijaya Vol. 32 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.01.9

Abstract

Medical students with high academic load have had elevated baseline rates of depression and poor sleep quality. During the COVID-19 pandemic, medical students are more susceptible to depression and poor sleep quality. This study aimed to analyze depression and sleep quality among medical students at the School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia (FKIK UAJ) during the COVID-19 pandemic. A cross-sectional study was conducted among pre-clinical and clinical students of FKIK UAJ academic year 2020/2021. Respondents were selected through proportional systematic random sampling to fulfill the Patient Health Questionnaire-9 (PHQ-9) and Pittsburgh Sleep Quality Index (PSQI) for depression and sleep quality. The data were analyzed using Mann Whitney U-Test. There were 63.3% of 635 respondents with depression, in which 39.4% respondents had mild depression, 14.2% respondents with moderate depression, and 9.8% respondents with severe depression. There were 59,2% of respondents with poor sleep quality. Depression was highest in females (67.2%) and pre-clinical stage of 2020 intake year (74.6%), and among clinical level students of 2018 (56%) and 2019 (53.9%) intake year. Poor sleep quality was also highest in females (62.8%) and pre-clinical 2020 intake year (69.8%), and among clinical level students of 2018 (53%) and 2019 (51.9%) intake year. The Mann-Whitney U-test showed a significant difference between depression level and sleep quality in pre-clinical and clinical students of FKIK UAJ during the COVID-19 pandemic (p value=0.000). Depression and sleep quality among medical students of FKIK UAJ during the COVID-19 pandemic were significantly associated.
Evaluation of the Antifertility Effect and Toxicity of Areca nut as Oral Contraceptive: Study on Male Rats Ave Olivia Rahman; Hasna Dewi; Billi Brian Geniro; Easti Vishiara Amdely
Jurnal Kedokteran Brawijaya Vol. 32 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.01.3

Abstract

Currently, very few male contraceptive methods are available. Areca nuts are known to have an antifertility effect, but the effective, safe dose is not certainly known. Data on its effectiveness and safety are needed to develop the potential of the areca nuts as an herbal contraceptive in men. This study determines the antifertility effect of areca nut administration at doses of 40, 30, and 20 mg/kgBW and their safety on the kidneys and liver. The green-colored raw areca nuts were used. The treatment groups were male rats whose fertility status was known before treatment. The control group were given distilled water. The treatment were given one dose a daily dissolved for 28 days of treatment, then male rats were bred again. Rats were terminated for histopathological examination of liver, kidneys, testes, and for analysis of spermatozoa. The administration of areca nuts caused a decreasing number of litters, but only the group given 40 mg/kgBW dose had a significant decrease (p<0.05). There were a damaged testes, a decreasing number and motility of spermatozoa as well as increasing spermatozoa abnormalities. There were no changes in liver tissue, but there was a mild grade cast in kidney tissue. Areca nut have antifertility effect in male rats with dose dependent manner, histopathological examination revealed cast nephotoxic but not hepatotoxic.

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