Wiwit Agung Sri Nur Cahyawati
Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran, Universitas Lambung Mangkurat

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Literature Review: Perbandingan Mobilitas Fungsional Pasien DM Tipe 2 dan Non-DM pada Lansia Rahmimi Azmi; Wiwit Agung Sri Nur Cahyawati; Roselina Panghiyangani
Homeostasis Vol 4, No 2 (2021)
Publisher : Homeostasis

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Abstract: Elderly, someone aged 60 years and over. The aging process is accompanied by a progressive loss of skeletal muscle mass and function. Elderly people often experience non-communicable diseases caused by decreased physiological functions that take place during the aging process. These non-communicable diseases include Diabetes Mellitus (DM). This paper aims to determine the differences in functional mobility of type 2 DM and non-DM patients in the elderly. Analyzes of related literature obtained from search results on medical journal databases, namely Pubmed-MEDLINE and Google Scholar. Articles included in English and published in 2008 to 2020. A total of 13 articles were included in this literature review. Functional mobility in the elderly with type 2 diabetes is worse than in the elderly without diabetes. The risk of falling is greater in the elderly with type 2 diabetes than in the elderly without diabetes. Keywords: elderly, mobility functional, diabetes mellitus type 2, timed up go,gait performance Abstrak: Lansia adalah seseorang yang berusia 60 tahun keatas. Proses penuaan disertai dengan hilangnya massa dan fungsi otot rangka secara progresif. Lanjut usia sering mengalami penyakit tidak menular yang disebabkan oleh penurunan fungsi fisiologis yang berlangsung selama proses menua. Penyakit tidak menular tersebut diantaranya Diabetes Mellitus (DM) Tulisan ini bertujuan untuk mengetahui perbedaan mobilitas fungsional pasien DM tipe 2 dan non DM pada lansia. Dilakukan analisis literatur terkait yang didapat dari hasil pencarian pada database jurnal kedokteran, yaitu Pubmed-MEDLINE dan Google Scholar. Artikel yang disertakan menggunakan bahasa inggris dan dipublikasikan pada tahun 2008 hingga 2020. Sebanyak 13 artikel disertakan pada literature review ini. Mobilitas fungsional pada lansia dengan DM tipe 2 lebih buruk dibandingkan lansia non DM. Risiko jatuh lebih besar pada lansia dengan DM tipe 2 dibanding dengan lansia non DM.  Kata-kata kunci: Lansia, mobilitas fungsional, diabetes mellitus tipe 2, timed up go, gaya berjalan
Literatur Review : Hubungan Indeks Massa Tubuh (IMT) dengan Massa Otot pada Lansia Dina Niswatin; Wiwit Agung Sri Nur Cahyawati; Lena Rosida
Homeostasis Vol 4, No 1 (2021)
Publisher : Homeostasis

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Abstract: Elderly are individuals aged 60 years and over. The nutritional status of elderly can be assessed by body mass index (BMI). BMI is related to muscle mass. BMI describes the overall body composition such as muscle, bone and fat. This paper aims to determine the relationship between BMI and muscle mass in the elderly. The writing is done by analyzing literature from medical journal database search results, namely PubMed – MEDLINE and Google Scholar. Articles included in English and published 2010-2020. A total of 20 articles are included in this literature review. BMI in the elderly is quite diverse, the elderly can have an abnormal BMI, namely underweight, overweight, and obese. The muscle mass of elderly men is greater than elderly women. The muscle mass of sarcopeni elderly has decreased compared to non-sarcopeni elderly. The relationship between BMI and muscle mass in the elderly showed mixed results, including a positive correlation between BMI and muscle mass and BMI as a risk factor and an important factor for sarcopeni. Keywords: elderly, body mass index, muscle mass, sarcopeni, bioelectrical impedance analysis Abstrak: Lansia adalah individu yang berusia 60 tahun ke atas. Status gizi lansia dapat dinilai dengan indeks massa tubuh (IMT). IMT berhubungan dengan massa otot. IMT menggambarkan komposisi tubuh secara keseluruhan seperti otot, tulang, dan lemak. Tulisan ini bertujuan untuk mengetahui hubungan IMT dengan massa otot pada lansia.  Penulisan dilakukan dengan menganalisis literatur dari hasil pencarian database jurnal kedokteran, yaitu PubMed–MEDLINE dan Google Scholar. Artikel yang disertakan menggunakan bahasa Inggris dan dipublikasikan tahun 2010-2020. Sebanyak 20 artikel disertakan pada literature review ini. IMT pada lansia cukup beragam, lansia dapat memiliki IMT abnormal yaitu underweight, overweight, dan obesitas. Massa otot lansia laki-laki rata-rata lebih besar dari lansia wanita. Massa otot lansia sarcopeni lebih rendah dari lansia non-sarcopeni. Hubungan IMT dengan massa otot pada lansia menunjukkan adanya korelasi positif IMT dengan massa otot, serta terkait IMT sebagai faktor risiko dan faktor penting terjadinya sarcopeni. Kata-kata kunci:  lansia, indeks massa tubuh, massa otot, sarcopeni,  bioelectrical impedance analysis
Literature Review: Perbandingan Massa Otot Pasien DM Tipe 2 dan Non-DM pada Lansia Nurfadilah Nurfadilah; Wiwit Agung Sri Nur Cahyawati; Roselina Panghiyangani
Homeostasis Vol 4, No 3 (2021)
Publisher : Homeostasis

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Abstract: Elderly are individuals aged 60 years and over. The aging process will result in a decrease in the function of pancreatic β cells which results in the incidence of Diabetes Mellitus (DM). This review aims to determine the differences in muscle mass of type 2 diabetes mellitus patients and non-diabetic in the elderly and to understand the pathophysiology of the causes of decreased muscle mass in patients with type 2 diabetes mellitus and non-diabetic elderly. The writing was conducted by analyzing the related literature obtained from search results on medical journal databases, such as PubMed - MEDLINE, Garuda and Google Scholar. The articles included in this literature review study were 15 articles between 2005-2020. The prevalence of decreased muscle mass increases with age. Reduced physical activity, nutritional status, immunology and changes in hormonal causes a decrease in muscle mass in the elderly. Elderly with type 2 diabetes have lower muscle mass than elderly non-diabetic. Keywords: Elderly, muscle mass, diabetes mellitus type 2, bioimpedance analysis, dual-energy x-ray absorptiometry Abstrak: Lansia adalah  individu berusia 60 tahun keatas. Proses penuaan akan mengakibatkan penurunan fungsi sel β pancreas yang berakibat terjadinya penyakit Diabetes Mellitus (DM). Penulisan literature review ini bertujuan untuk mengetahui perbedaan massa otot pasien DM tipe 2 dan non-DM pada lansia, dan untuk memahami patofisiologi penyebab penurunan massa otot pasien DM tipe 2 dan non-DM pada lansia. Penulisan dilakukan dengan menganalisis literature terkait yang didapatkan dari hasil pencarian pada database jurnal kedokteran, yaitu PubMed – MEDLINE, Garuda dan Google Scholar. Artikel yang disertakan sebanyak 15 artikel antara tahun 2005-2020. Prevalensi penurunan massa otot meningkat seiring dengan bertambahnya usia. Berkurangnya aktivitas fisik, status nutrisi, imunologi dan perubahan pada hormonal menyebabkan penurunan massa otot pada lansia.Lansia dengan DM tipe 2 memiliki massa otot yang lebih rendah dibandingkan dengan lansia non-DM. Kata-kata kunci: Lansia, massa otot, diabetes mellitus tipe 2, bioimpedance analysis, dual-energy x-ray absorptiometry
Hubungan Kadar Albumin, Limfosit, dan Komorbiditas dengan Lama Rawat Inap Aisy Samara Istiqomah; Wiwit Agung Sri Nur Cahyawati; Roselina Panghiyangani
Homeostasis Vol 5, No 2 (2022)
Publisher : Homeostasis

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Abstract: Hypoalbuminemia is common in the elderly patients. Along with aging there is a decrease in physiological functions including the immune system which causes lymphopenia. Comorbidities also increase significantly with age. This research is analytic observational with cross-sectional method aimed to analyze the correlation of albumin, lymphocytes, and comorbidities with the length of stay of elderly patients. The research sample of 31 elderly people was obtained using a total sampling technique according to the inclusion and exclusion criteria. The mean albumin level was 3.07±0.61 gr/dl. The mean lymphocyte value was 17.84±9.68 %. The median comorbidity score was 2 with a minimum was 0 and the maximum was 4. The average length of stay for elderly patients was 7±3.84 days. There is a significant correlation between lymphocytes and LOS in elderly patients (r=-0,45;p=0,011). There is a significant correlation between comorbidities and LOS in elderly patients (r=0,368;p=0,042). There is no correlation between albumin and LOS of elderly patients (p>0.05) in the Internal Medicine Ward at Ulin Hospital Banjarmasin. Keywords: albumin levels, lymphocyte, comorbidity, length of stay, elderly Abstrak: Hipoalbuminemia umum ditemukan pada lansia. Seiring dengan peningkatan usia terjadi penurunan fungsi fisiologis termasuk pada sistem imunitas yang pada akhirnya menyebabkan limfopenia. Komorbiditas pun meningkat secara signifikan seiring bertambahnya usia. Penelitian ini bersifat observasional analitik dengan metode cross-sectional dan bertujuan untuk menganalisis korelasi albumin, limfosit, dan komorbiditas dengan lama rawat inap pasien lansia. Sampel penelitian sejumlah 31 lansia diperoleh menggunakan teknik total sampling sesuai kriteria inklusi dan eksklusi. Rerata kadar albumin 3,07 gr/dl±0,61. Rerata nilai limfosit 17,84%±9,68. Median skor komorbiditas didapatkan skor 2 dengan minimal 0 dan maksimal 4. Rerata lama rawat inap pasien lansia adalah 7±3,84 hari. Terdapat korelasi signifikan antara limfosit dan lama rawat pasien lansia (r=-0,45; p=0,011). Terdapat korelasi signifikan antara komorbiditas dan lama rawat pasien lansia (r=0,368; p=0,042). Tidak terdapat korelasi antara albumin dengan lama rawat pasien lansia (p>0,05) di Ruang Rawat Penyakit Dalam RSUD Ulin Banjarmasin. Kata-kata kunci: kadar albumin, limfosit, komorbiditas, lama rawat inap, lansia
Literature Review: Perbandingan Kekuatan Otot Pasien DM Tipe 2 dan Non-DM pada Lansia Asmah Aulia; Wiwit Agung Sri Nur Cahyawati; Roselina Panghiyangani
Homeostasis Vol 4, No 2 (2021)
Publisher : Homeostasis

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Abstract: Elderly is someone over 60 years of age who experiences a natural aging process characterized by decreased physical ability due to changes in the function of organs and body systems which results in various diseases, one of which is type 2 diabetes. Aging is related to a progressive decrease in skeletal muscle strength. The purpose of this review literature is to determine the differences in muscle strength in patients with type 2 diabetes and non-DM patients in the elderly by analyzing the related literature obtained from search results in medical journal databases, namely Pubmed-MEDLINE and Google Scholar. There are 20 articles included in English and published in 2004-2020. Decreased muscle strength in the elderly due to increased visceral fat and intramuscular fat while subcutaneous fat, the number and size of muscle fibers decreased. The decrease in muscle strength in DM is due to insulin resistance resulting in a decrease in protein synthesis and an increase in protein degradation. So it can be concluded that the elderly with type 2 DM have lower muscle strength than non-DM. Keywords: elderly, muscle strength, diabetes mellitus type 2, non DM, hand grip strength. Abstrak: Lansia adalah seseorang berusia diatas 60 tahun yang mengalami proses penuaan alami ditandai menurunnya kemampuan fisik akibat perubahan fungsi organ dan sistem tubuh yang berakibat pada berbagai penyakit salah satunya DM tipe 2. Penuaan berkaitan dengan menurunnya kekuatan otot rangka secara progresif. Tujuan literatur review ini untuk mengetahui perbedaan kekuatan otot pasien DM tipe 2 dan non DM pada lansia dengan menganalisis literatur terkait yang didapatkan dari hasil pencarian pada database jurnal kedokteran, yaitu Pubmed-MEDLINE dan Google Scholar. Artikel yang disertakan sebanyak 20 menggunakan bahasa inggris dan dipublikasikan pada tahun 2004-2020. Penurunan kekuatan otot pada lansia karena lemak visceral dan lemak intramuscular meningkat sedangkan lemak subkutan, jumlah dan ukuran serat otot menurun. Penurunan kekuatan otot pada DM disebabkan resistensi insulin  sehingga terjadi penurunan sintesis protein dan peningkatan degradasi protein. Sehingga dapat disimpulkan lansia dengan DM tipe 2 memiliki kekuatan otot yang lebih rendah dibandingkan non DM. Kata-kata kunci:  lansia, kekuatan otot, diabetes melitus tipe 2, non DM, hand grip strength.Abstract:Elderly is someone over 60 years of age who experiences a natural aging process characterized by decreased physical ability due to changes in the function of organs and body systems which results in various diseases, one of which is type 2 diabetes. Aging is related to a progressive decrease in skeletal muscle strength. The purpose of this review literature is to determine the differences in muscle strength in patients with type 2 diabetes and non-DM patients in the elderly by analyzing the related literature obtained from search results in medical journal databases, namely Pubmed-MEDLINE and Google Scholar. There are 20 articles included in English and published in 2004-2020. Decreased muscle strength in the elderly due to increased visceral fat and intramuscular fat while subcutaneous fat, the number and size of muscle fibers decreased. The decrease in muscle strength in DM is due to insulin resistance resulting in a decrease in protein synthesis and an increase in protein degradation. So it can be concluded that the elderly with type 2 DM have lower muscle strength than non-DM. Keywords: elderly, muscle strength, diabetes mellitus type 2, non DM, hand grip strength. Abstrak: Lansia adalah seseorang berusia diatas 60 tahun yang mengalami proses penuaan alami ditandai menurunnya kemampuan fisik akibat perubahan fungsi organ dan sistem tubuh yang berakibat pada berbagai penyakit salah satunya DM tipe 2. Penuaan berkaitan dengan menurunnya kekuatan otot rangka secara progresif. Tujuan literatur review ini untuk mengetahui perbedaan kekuatan otot pasien DM tipe 2 dan non DM pada lansia dengan menganalisis literatur terkait yang didapatkan dari hasil pencarian pada database jurnal kedokteran, yaitu Pubmed-MEDLINE dan Google Scholar. Artikel yang disertakan sebanyak 20 menggunakan bahasa inggris dan dipublikasikan pada tahun 2004-2020. Penurunan kekuatan otot pada lansia karena lemak visceral dan lemak intramuscular meningkat sedangkan lemak subkutan, jumlah dan ukuran serat otot menurun. Penurunan kekuatan otot pada DM disebabkan resistensi insulin  sehingga terjadi penurunan sintesis protein dan peningkatan degradasi protein. Sehingga dapat disimpulkan lansia dengan DM tipe 2 memiliki kekuatan otot yang lebih rendah dibandingkan non DM. Kata-kata kunci:  lansia, kekuatan otot, diabetes melitus tipe 2, non DM, hand grip strength.
Korelasi Rasio Neutrofil Limfosit dengan Lama Rawat Inap Diah Ayu Wikan Nastiti; Wiwit Agung Sri Nur Cahyawati; Roselina Panghiyangani
Homeostasis Vol 5, No 1 (2022)
Publisher : Homeostasis

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Abstrack: Systemic inflammation can be characterized by an increased NLR. Systemic inflammation induce physiological changes, vulnerability, and even death. Elderly often experience various health complaints that cause prolonged hospitalization. Increased NLR is clinical marker that can be a preventive measure to predict length of stay. This study aims to analize correlation of NLR and length of stay of elderly. An analytical observasional with cross-sectional method using secondary data from medical records at RSUD Ulin Banjarmasin period July-November 2021.  Total 44 samples using total sampling technique. Data analysis used non-parametric correlation Spearman. Median NLR 7.7 (1,3-73,3). Median length of stay 5.5 (1-16) days, average age of the elderly 66±4.65 years. There is a significant relationship between NLR and length of stay with a weak correlation and positive direction (r=0.392; p=0.008). The conclution is there is a relationship between NLR and length of stay of elderly in Internal Room at RSUD Ulin Banjarmasin. Keywords: elderly, neutrophil lymphocyte ratio, length of stay. Abstrak: Inflamasi sistemik dapat ditandai dengan peningkatan RNL Inflamasi sistemik mengakibatkan perubahan fisiologis tubuh, kerentanan, bahkan kematian. Lansia sering mengalami berbagai keluhan yang menyebabkan rawat inap memanjang. Peningkatan RNL merupakan penanda klinis yang dapat menjadi upaya preventif untuk memprediksi lama rawat. Penelitian ini bertujuan menganalisis korelasi RNL dengan lama rawat inap pasien lansia. Penelitian observasional analitik dengan metode cross-sectional menggunakan data sekunder rekam medik RSUD Ulin Banjarmasin periode Juli-November 2021. Sampel sejumlah 44 menggunakan teknik total sampling. Analisis data menggunakan uji korelasi non-parametrik Spearman. Median RNL 7,7 (1,3-73,3). Median lama rawat inap 5,5 (1-16) hari, rerata umur lansia 66±4,65 tahun. Terdapat hubungan bermakna antara RNL terhadap lama rawat inap berupa korelasi lemah serta arah hubungan positif (r=0,392; p=0.008). Kesimpulan terdapat hubungan antara RNL dengan lama rawat inap pasien lansia di Ruang Rawat Penyakit Dalam RSUD Ulin Banjarmasin. Kata-kata kunci: lansia, rasio neutrofil limfosit, lama rawat inap. 
Impact of E2 and FSH levels on the severity of Stress Urinary Incontinence (SUI) in menopausal women Leny Suardi; Pribakti Budinurdjaja; Wiwit Agung Sri Nurcahyawati; Meitria Syahadatina Noor
Majalah Obstetri & Ginekologi Vol. 30 No. 2 (2022): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I22022.92-100

Abstract

HIGHLIGHTS 1. E2 and FSH levels in menopausal women are thought to have relationship with stress urinary incontinensia (SUI).2. It was found that E2 and FSH levels had no significant relationship with SUI severity in menopausal women.   ABSTRACT Objectives: This study aimed to analyze the relationship between E2 and FSH levels in menopausal women with the severity of Stress Urinary Incontinence (SUI) at Ulin Hospital, Banjarmasin, Indonesia. Materials and Methods: This study used an analytic observational method with cross-sectional design in menopausal women diagnosed with Urinary Incontinence (UI) from October 2020 - March 2021. The independent variables were E2 and FSH levels. The dependent variable was the severity of SUI in menopausal women. The severity of SUI was determined by the Incontinence Severity Index (ISI) scoring. Data were analyzed by Spearman correlation. Results: The subjects who met the criteria were 25 women. The results showed the prevalence rate of SUI was 5.8% with E2 and FSH levels of mild SUI (14.25 pg/mL and 49.70 mIU/mL), moderate (7.91 pg/mL and 54.13 mIU/mL), and severe (9.14 pg/mL) and 70.97 mIU/mL). The number of severity levels of mild SUI was 44%, moderate SUI was 48%, and severe SUI was 8%. Most patients with SUI aged >60 years, multipara, normal body mass index (BMI), duration of menopause <10 years, menarche <15 years, Intrauterine Device (IUD) contraception, and delivered with spontaneous vaginal delivery. There was no significant relationship between E2 levels and the severity of SUI with a p-value of 0.084 and a correlation coefficient of -0.353. There was no significant relationship between FSH level and severity of SUI with a p-value of 0.367 and a correlation coefficient of 0.189. Conclusion: There was no significant relationship between E2 and FSH levels and the severity of SUI in menopausal women. It is necessary to do research on other factors that influence the high severity of SUI in menopausal women.  
Relationship between Nutritional Status, Frailty, and Cognitive Function among Elderly at Dr. H. Moch. Ansari Saleh General Hospital Banjarmasin Wiwit Agung Sri Nur Cahyawati; Roselina Panghiyangani; Muhammad Syauqi Abid Muslim; Novia Belinda Rahman
Jurnal Kedokteran Brawijaya Vol. 32 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.01.10

Abstract

The elderly often have nutritional problems. The risk of malnutrition can stimulate the prevalence of frailty and declining cognitive function in the elderly. The study aimed to analyze the relationship between nutritional status, frailty, and cognitive function in the elderly at Dr. H. Moch. Ansari Saleh Hospital Banjarmasin. This study was analytic observational using a cross-sectional method. A sample of 93 elderly was obtained using a total sampling technique according to the inclusion and exclusion criteria. The nutritional status assessment was done using the Mini Nutritional Assessment-Short Form (MNA-SF), the Edmonton Frailty Scale (EFS), and the Mini-Mental State Examination (MMSE). The results showed that the mean of Mini Nutritional Assessment score was 12.00±2.126, the average frailty score was 4.41±1.872, and the average value of cognitive function was 25.98±2.923. Data were analyzed using the Spearman's non-parametric correlation test with a 95% confidence level. The correlation test results between nutritional status and frailty obtained p=0.000 and r=-0.490. The correlation test results between nutritional status and cognitive function obtained p=0.000 and r=0.595. In short, there is a relationship between nutritional status on frailty and cognitive function in the elderly at Dr. H. Moch. Ansari Saleh General Hospital Banjarmasin, it means that the good nutritional status in the elderly, the risk of frailty syndrome will decrease and improve cognitive function.
HUBUNGAN NILAI MINI NUTRITIONAL ASSESSMENT (MNA) DENGAN LAMA RAWAT INAP Siti Hafizhah Fatimah; Wiwit Agung Sri Nur Cahyawati; Roselina Panghiyangani
Homeostasis Vol 5, No 3 (2022)
Publisher : Homeostasis

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Mini Nutritional Assessment (MNA) is an instrument for assessing and screening specific nutritional in the elderly. Elderly are vulnerable to malnutrition because of physiological and functional changes that contribute to increase length of stay. The purpose of this study was to determine the correlation between Mini Nutritional Assessment value with length of stay of elderly patients at RSUD Ulin Banjarmasin. This research is analytic observational with cross-sectional method. A sample of 32 elderly patients was analysis used Spearman correlation test. The  median MNA value was 20.00 points and the median length of stay was 8.00 days. The results of the correlation test showed that the value of p = 0.002 and value of r = -0.532 which means there is a significant correlation and a strong correlation with a negative direction. It can be concluded that there is a correlation between the Mini Nutritional Assessment (MNA) value with length of stay of elderly patients in internal medicine ward at RSUD Ulin Banjarmasin.
HUBUNGAN ANTARA USIA DAN JENIS KELAMIN DENGAN KEJADIAN STROKE PADA PASIEN DIABETES MELITUS DI RSUD ULIN BANJARMASIN Theresa Tyra Sertani; Nanang Miftah Fajari; Mohammad Bakhriansyah; Wiwit Agung Sri Nur Cahyawati; Dona Marisa
Homeostasis Vol 6, No 1 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i1.8802

Abstract

Diabetes melitus (DM) merupakan penyakit kronis yang ditandai dengan terjadinya peningkatan kadar glukosa darah melebihi normal atau hiperglikemia, salah satu penyakit kardiovaskuler yang berisiko besar terjadi pada penderita DM adalah stroke. Usia dan jenis kelamin merupakan faktor yang diduga berpengaruh terhadap terjadinya risiko stroke pada pasien DM. Tujuan penelitian ini untuk mengetahui hubungan antara usia dan jenis kelamin dengan kejadian stroke pada pasien DM. Penelitian observasional analitik ini menggunakan pendekatan potong lintang pada 108 pasien yang tercatat di pangkalan data milik Poliklinik Endokrin RSUD Ulin Banjarmasin yaitu BEST DIAB 2 (Borneo Wetland Study on Diabetes 2). Pengambilan sampel secara total sampling untuk pasien stroke dan simple random sampling untuk pasien tidak stroke dengan perbandingan 1:1. Data dianalisis dengan uji Fisher’s exact dan Chi-square menggunakan perangkat lunak statistik SPSS versi 26. Penelitian ini menunjukkan tidak ada hubungan antara usia (p=0,205) dan jenis kelamin (p=1,00) terhadap kejadian stroke pada pasien DM di RSUD Ulin Banjarmasin.