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Jurnal Anestesiologi dan Terapi Intensif
Published by Universitas Udayana
ISSN : 30903580     EISSN : 30903580     DOI : https://doi.org/10.24843
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Anestesiologi dan Terapi Intensif (JATI) is the official publication of the Department of Anesthesiology and Intensive Care, Udayana University, Indonesia. The journal is dedicated to advancing knowledge, research, and clinical practice in the fields of anesthesiology, intensive care, pain medicine, and perioperative medicine. Aims The primary aim of JATI is to serve as a platform for disseminating high-quality, peer-reviewed scientific work that contributes to the improvement of patient care, education, and research in anesthesiology and intensive care. The journal seeks to: - Promote the integration of clinical practice, research, and education in perioperative and critical care medicine. - Encourage the publication of innovative research, case-based learning, and evidence-based reviews. - Provide opportunities for academic exchange among clinicians, researchers, and educators at the national and international levels. - Uphold ethical publishing standards and support the development of early-career researchers and clinicians. Scope JATI publishes original articles, review articles, case reports, study protocols, editorials, and commentaries covering a broad range of topics, including but not limited to: - General anesthesia and regional anesthesia - Perioperative medicine and patient safety - Critical care and intensive care medicine - Pain medicine, pain management, and interventional procedures - Resuscitation, trauma, and emergency medicine - Basic and translational anesthesia sciences - Clinical pharmacology and therapeutics - Ethics, professionalism, and medical law in anesthesiology - Simulation, education, and training in anesthesiology and critical care The journal operates on an open access model under the Creative Commons Attribution (CC BY 4.0) license, ensuring that all published articles are freely available to readers worldwide. Manuscripts are subject to rigorous double-blind peer review to ensure scientific quality and integrity.
Arjuna Subject : Kedokteran - Anesthesiology and Pain Medicine
Articles 44 Documents
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Efficacy of Pregabalin Versus Gabapentin as Preemptive Analgesia in Patients Undergoing Modified Radical Mastectomy: a Randomized Controlled Trial Yolanda Jenny Yolanda Jenny; Made Septyana Parama Adi; I Putu Kurniyanta; I Putu Pramana Suarjaya
Jurnal Anestesiologi dan Terapi Intensif Vol. 2 No. 2 (2026): JATI AUGUST
Publisher : Udayana University and Indonesian Society of Anesthesiologists (PERDATIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/7btvrm40

Abstract

Introduction: Postoperative pain after modified radical mastectomy (MRM) increases morbidity, opioid use, and recovery time. Gabapentinoids may reduce central sensitization when administered before surgical injury. This study compared pregabalin and gabapentin as preemptive analgesics in patients undergoing MRM. Patients and Methods: This double-blind randomized controlled trial was conducted at Ngoerah Hospital, Denpasar. Forty-two patients scheduled for elective MRM were allocated to oral pregabalin 150 mg (n = 21) or oral gabapentin 900 mg (n = 21), administered two hours before surgery. The primary outcome was Visual Analogue Scale (VAS) pain score at 12, 24, and 48 hours postoperatively. Secondary outcomes were time to first rescue analgesia and cumulative opioid consumption during the first 24 postoperative hours. Between-group comparisons used the independent t-test or Mann-Whitney U test, as appropriate. Results: Pregabalin produced lower VAS scores than gabapentin at 12 hours (2.18 +/- 0.65 vs 2.65 +/- 0.74; p = 0.034), 24 hours (2.27 +/- 0.66 vs 2.71 +/- 0.63; p = 0.030), and 48 hours (1.90 +/- 0.65 vs 2.36 +/- 0.71; p = 0.033). Time to first rescue analgesia was longer with pregabalin (232.69 +/- 19.88 vs 219.88 +/- 17.81 minutes; p = 0.034), and 24-hour opioid consumption was lower (240 [145] vs 360 [155] micrograms fentanyl equivalent; p = 0.034). No adverse hemodynamic. Conclusion: Preoperative oral pregabalin 150 mg provided statistically superior analgesia and reduced opioid consumption compared with gabapentin 900 mg after MRM. However, the absolute differences in pain scores and rescueanalgesia time were modest; therefore, safety monitoring and larger studies are warranted
Faster Induction, Lower Consumption, and Quicker Recovery: A Comparison of Eleveld and Schnider TCI Models for Sedation in Outpatient Colonoscopy Aditya Wangsa; I Gusti Agung Made Wibisana Kurniajaya; Tjahya Aryasa EM Tjahya; I Made Gede Widnyana Widnyana
Jurnal Anestesiologi dan Terapi Intensif Vol. 2 No. 2 (2026): JATI AUGUST
Publisher : Udayana University and Indonesian Society of Anesthesiologists (PERDATIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/76rd7r30

Abstract

Introduction: Outpatient colonoscopy is commonly performed under sedation, and propofol is frequently selected because of its rapid onset and short recovery profile. Target-controlled infusion (TCI) may improve dosing precision, but the comparative performance of the Eleveld and Schnider models during outpatient colonoscopy remains insufficiently defined. This study compared the Eleveld and Schnider TCI models for propofol sedation in patients undergoing outpatient colonoscopy. Patients and Methods: This randomized, participant- and assessor-blinded, parallel-group controlled trial included 36 adults aged 20-65 years with ASA physical status I-III and BMI <30 kg/m2 who underwent elective outpatient colonoscopy. Participants were allocated to receive propofol using either the Eleveld or Schnider TCI model. The initial effect-site concentration was 2 µg/mL and was titrated by 0.5 µg/mL until a BIS value of 70 was achieved. The primary outcome was induction time, defined as the time from propofol infusion initiation to BIS 70. Secondary outcomes were mean propofol consumption, number of effect-site concentration adjustments, post-procedural agitation assessed using RASS, and recovery time to GCS 15. Results: The Eleveld model was associated with shorter induction time than the Schnider model (4.03 ± 0.81 vs 5.32 ± 0.98 minutes; p <0.001) and lower propofol consumption (92.47 ± 28.29 vs 119.24 ± 31.56 µg/kg/min; p = 0.011). Recovery time was also shorter in the Eleveld group (5.27 ± 1.71 vs 7.88 ± 1.94 minutes; p <0.001). The number of effect-site concentration adjustments and postprocedural agitation did not differ significantly between groups. Conclusion: The Eleveld TCI model was associated with faster induction, lower propofol consumption, and faster recovery than the Schnider model during outpatient colonoscopy, with comparable sedation adjustment requirements and post-procedural agitation. These findings suggest that the Eleveld model may improve sedation efficiency in this setting, although larger studies are needed to confirm its clinical and safety advantages.
Comparison of Continuous and Intermittent Bolus Enteral Nutrition in Patients with Severe Traumatic Brain Injury: A Randomized Controlled Trial Agiel Fahlevie Choirunanda; I Wayan Aryabiantara; Ida Bagus Krisna Jaya Sutawan; I Gusti Putu Sukrana Sidemen
Jurnal Anestesiologi dan Terapi Intensif Vol. 2 No. 2 (2026): JATI AUGUST
Publisher : Udayana University and Indonesian Society of Anesthesiologists (PERDATIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/mp322r75

Abstract

Introduction: Severe traumatic brain injury (TBI) is associated with impaired gastric motility and dysregulated glucose homeostasis, making optimal enteral nutrition challenging. This study compared continuous and intermittent bolus enteral nutrition in terms of gastric residual volume (GRV), glycemic variability, and gastrointestinal tolerance in patients with severe TBI. Patients and Methods: An assessor-blinded, randomized controlled trial was conducted in 60 adult patients with severe TBI admitted to the intensive care unit. Participants were randomly assigned to continuous (n = 30) or intermittent bolus enteral nutrition (n = 30) during the first 24 hours after ICU admission. GRV was measured every 4 hours using gastric ultrasonography. Glycemic variability was assessed using the coefficient of variation (CV), and diarrhea was recorded as a marker of gastrointestinal tolerance. GRV was analyzed using repeatedmeasures analysis of variance (ANOVA), while glycemic fluctuation and diarrhea incidence were analyzed using Fisher’s exact and chi-square tests. Results: Sixty patients were analyzed, with comparable baseline characteristics between groups. Repeated-measures ANOVA demonstrated a significant overall effect of feeding method on GRV (F(1,58) = 158.235, p < 0.001) and a significant time × group interaction (Greenhouse–Geisser corrected F(3.980,230.814) = 3.437, p = 0.010). During the 24-hour observation period, continuous feeding resulted in a lower overall GRV than intermittent bolus feeding (mean difference 18.9 mL; 95% CI 15.9–21.9). Glycemic fluctuation was similar between groups (p = 0.500), whereas diarrhea occurred less frequently with continuous feeding (20.0% vs 50.0%, p = 0.008).  Conclusion: During the first 24 hours of ICU admission, continuous enteral nutrition was associated with lower overall GRV and a lower incidence of diarrhea than intermittent bolus feeding, while glycemic fluctuation was comparable between groups. Further studies are warranted to evaluate long-term clinical outcomes.
Anesthesia Management in Aneurysm Clipping Surgery with Chilaiditi Sign : a Case Report Wisnu Wardhana; I Putu Pramana Suarjaya
Jurnal Anestesiologi dan Terapi Intensif Vol. 2 No. 2 (2026): JATI AUGUST
Publisher : Udayana University and Indonesian Society of Anesthesiologists (PERDATIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/x59n1t02

Abstract

Chilaiditi sign is the asymptomatic interposition of the colon between the liver and diaphragm; when accompanied by gastrointestinal symptoms, it is termed Chilaiditi syndrome. Its coexistence with aneurysmal subarachnoid haemorrhage creates competing anaesthetic priorities, including aspiration prevention, lung protection, and control of cerebral haemodynamics. We report a 79-year-old woman who presented with sudden severe headache and transient loss of consciousness. Imaging demonstrated subarachnoid haemorrhage from a ruptured left posterior communicating artery aneurysm, together with incidental colonic interposition beneath an elevated right hemidiaphragm, bilateral pleural effusions, and partial right-lower-lobe collapse. After 10 hours of fasting and pharmacological aspiration-risk mitigation, general anaesthesia was induced with thiopental, remifentanil, and rocuronium using a modified rapid-sequence approach that included preoxygenation, cricoid pressure, gentle mask ventilation, and video laryngoscopy. Pressure-controlled ventilation and close haemodynamic control were maintained throughout aneurysm clipping. No intraoperative rupture, aspiration, haemodynamic instability, or respiratory deterioration occurred. The patient was extubated 36 hours after surgery and discharged on postoperative day 8 with a modified Rankin Scale score of 1. This case highlights the need to individualise induction and ventilation when Chilaiditi sign coexists with urgent intracranial surgery. The uneventful outcome of a single case should not be interpreted as evidence that modified induction is generally safer than classical rapid-sequence induction.

Page 5 of 5 | Total Record : 44

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