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Science Get Journal
Published by CV. Get Press Indonesia
ISSN : -     EISSN : 30626595     DOI :  http://doi.org/10.69855/science
Core Subject : Science, Education,
Biochemistry, Genetics & Molecular Biology Chemistry Mathematics Physics
A Peer Reviewed Research Science Get Journal e-ISSN: 3062-6595 Science Get Journal is an Open Access and Anonymous Reviewer/Anonymous Author journal. The field of Science is a vehicle for scientific communication in the field of Science which covers the cross-fields of Mathematics, Physics, Chemistry, Biology, Geography and Mathematics,  Natural Sciences Education and Social Sciences. Science Get Journal is published by Get Press Indonesia. Science Get Journal is used to publish research published every month January, April, July, and October. The Science Get Journal template can be downloaded here (Click). Information about article submission: Articles sent by the author (author) will be seen and read by the editor, if there are still discrepancies with the applicable template and do not comply with the scope of Science Get Journal then the article will be returned to the author. If it is appropriate, the article will be forwarded to the Science Get Journal reviewer for a review process carried out by the Science Get Journal reviewer. A total of two reviewers within a two week period of evaluating the article.
Arjuna Subject : Matematika - Matematika (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol 3 No 2 (2026): April, 2026" : 5 Documents clear
Zeolite Nanocomposites from Coal Fly Ash for Arsenic Removal in Wastewater Erlinda Ningsih; Hanifah Sriamelia; Salsabilla
Science Journal Get Press Vol 3 No 2 (2026): April, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i2.575

Abstract

Arsenic contamination in wastewater poses serious environmental and public health risks because of its toxicity, persistence, and bioaccumulation potential. This study investigated the synthesis and performance of magnetic zeolite nanocomposites (MZN) derived from coal fly ash (CFA) for efficient As(V) removal from wastewater. CFA obtained from the PT PLN Ombilin Power Plant, West Sumatra, Indonesia, was converted into zeolite NaA/NaX through an alkaline hydrothermal method and subsequently modified with Fe₃O₄ nanoparticles to enhance adsorption capacity and magnetic separability. The synthesized MZN was characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy with energy dispersive X-ray analysis (SEM-EDX), Brunauer–Emmett–Teller (BET), and vibrating sample magnetometer (VSM) analyses. Batch adsorption experiments were conducted to evaluate the effects of pH, contact time, adsorbent dosage, initial arsenic concentration, and temperature on adsorption performance. The maximum As(V) removal efficiency reached 97.4% under optimum conditions of pH 6, adsorbent dosage of 2 g/L, and contact time of 120 min. Adsorption behavior followed the Langmuir isotherm and pseudo-second-order kinetic models, indicating monolayer chemisorption. Thermodynamic analysis confirmed a spontaneous and endothermic process. Regeneration tests showed that MZN maintained over 85% removal efficiency after five adsorption–desorption cycles, demonstrating its potential as an effective, reusable, and low-cost adsorbent for industrial wastewater treatment.
Metabolite Profiling of Bryophyte Endophytes: Novel Antioxidants from Indonesian Mosses Ferdinand Susilo; Ilyas Fakhrizal
Science Journal Get Press Vol 3 No 2 (2026): April, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i2.580

Abstract

Indonesian bryophytes harbor diverse endophytic microorganisms that are promising sources of novel bioactive compounds with potential pharmaceutical and antioxidant applications. This study investigated the secondary metabolite profiles of endophytic fungi isolated from Indonesian moss species using liquid chromatography–tandem mass spectrometry (LC–MS/MS) and nuclear magnetic resonance (NMR) spectroscopy. A total of 47 fungal isolates belonging to five genera were obtained from mosses collected in Java and Sumatra, Indonesia. Metabolomic profiling detected 312 molecular features, indicating high chemical diversity among the isolates. Antioxidant screening using DPPH and ABTS assays identified 23 compounds with significant free radical scavenging activity. Principal component analysis (PCA) revealed clustering patterns based on host species, with endophytes from Leucobryum aduncum forming a distinct metabolomic group enriched in chromene-glycoside derivatives. Molecular networking analysis through the Global Natural Products Social Molecular Networking (GNPS) platform revealed a putative novel polyketide cluster absent from existing databases. Bioassay-guided fractionation and structural elucidation led to the discovery of four new compounds, leucobryosides A–D. Among them, leucobryoside A showed the strongest antioxidant activity with an IC₅₀ value of 12.3 ± 1.8 μg/mL, comparable to ascorbic acid. These findings highlight Indonesian bryophyte endophytes as valuable sources of natural antioxidant compounds for future pharmaceutical and biotechnological applications.
Green-Synthesized Carbon Quantum Dots from Banana Peel Waste for Sustainable Label-Free Fluorescent Biosensing of Prostate Cancer Biomarker Nor Pana Yupa; Dian Putri Mustika
Science Journal Get Press Vol 3 No 2 (2026): April, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i2.602

Abstract

A novel fluorescent biosensing platform for the label-free, sustainable detection of prostate-specific antigen (PSA) was developed using green-synthesized carbon quantum dots (CQDs) derived from banana peel (Musa acuminata) agricultural waste. CQDs were fabricated via a one-step hydrothermal carbonization at 200°C for 8 hours, yielding quasi-spherical nanoparticles with an average diameter of 3.2 ± 0.5 nm, a quantum yield of 18.4%, and characteristic blue emission at 460 nm (λex = 360 nm). Rich surface functionalization with hydroxyl (–OH), carboxyl (–COOH), and amino (–NH₂) groups enabled covalent conjugation of a PSA-specific aptamer via EDC/NHS coupling chemistry. The resulting CQD-aptamer biosensor exhibited a broad linear detection range of 0.01–50 ng/mL with an ultralow limit of detection (LOD) of 0.008 ng/mL (S/N = 3), well within the clinical diagnostic threshold of 4 ng/mL for PSA monitoring. Selectivity studies demonstrated negligible cross-reactivity (<3.5%) against common serum interferents including CEA, AFP, albumin, and glucose. Spike-and-recovery experiments in diluted human serum yielded recovery values of 96.8–103.2% with RSDs below 2.5%, confirming robust performance in complex biological matrices. Estimated material costs (~$0.12/mg CQD) and the waste-valorization approach align with green chemistry principles and circular economy objectives. This work establishes banana peel-derived CQDs as cost-effective, eco-friendly, and analytically competitive nanoprobes for point-of-care cancer biomarker detection.
Extracellular Vesicles Derived from Fermented Soybean (Glycine max) as a Platform for Targeted Drug Delivery in Colorectal Cancer: Isolation, Characterization, and In Vitro/In Vivo Evaluation Rolef Rumondor; Abid Indra; Sonya Afrilla
Science Journal Get Press Vol 3 No 2 (2026): April, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i2.603

Abstract

Plant-derived extracellular vesicles (PDEVs) are promising nanocarriers for drug delivery, but their therapeutic performance is often limited by low bioactivity and targeting efficiency. This study developed a fermentation-engineered strategy to enhance soybean-derived extracellular vesicles using Lactobacillus plantarum. Fermented soybean EVs (FSE-EVs) were isolated and characterized through nanoparticle tracking analysis, transmission electron microscopy, and high-performance liquid chromatography (HPLC). Drug loading efficiency, pH-responsive release, and anticancer activity were evaluated in colorectal cancer (CRC) cell lines and xenograft mouse models. FSE-EVs showed smaller particle size, improved stability, and a 78% increase in miRNA cargo diversity compared to non-fermented EVs. HPLC analysis demonstrated high 5-fluorouracil (5-FU) encapsulation efficiency (78.3%) and controlled drug release under acidic conditions. Functionally, FSE-EVs loaded with 5-FU significantly enhanced anticancer activity, reducing IC50 values and increasing apoptosis in CRC cells. In vivo, the treatment achieved 83% tumor suppression with minimal systemic toxicity. These findings demonstrate that fermentation can transform PDEVs into an effective, scalable, and food-grade nanoplatform for gastrointestinal cancer therapy.
Microbial Fuel Cells Powered by Tempeh Wastewater: Electricity Generation and COD Removal Alfiah Alif
Science Journal Get Press Vol 3 No 2 (2026): April, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i2.605

Abstract

Tempeh, a traditional fermented soybean food product widely consumed in Indonesia and Southeast Asia, is produced through a solid-state fermentation process using Rhizopus oligosporus mold. Its production generates large volumes of organic-rich wastewater with Chemical Oxygen Demand (COD) reaching up to 5,000 mg/L, posing significant environmental challenges if discharged without treatment. This study investigates the application of Microbial Fuel Cells (MFCs) to simultaneously treat tempeh wastewater and generate bioelectricity. Three MFC configurations were evaluated: single-chamber, double-chamber (with Nafion 117 proton exchange membrane), and stacked systems, inoculated with mixed microbial consortia enriched from tempeh wastewater sludge. The stacked MFC achieved the highest electricity generation performance, with a maximum open-circuit voltage of 1,248.6 ± 28.3 mV and a maximum power density of 498.2 ± 19.6 mW/m², alongside the highest COD removal efficiency of 88.9 ± 2.1% and Coulombic Efficiency of 31.4%. Electrochemical characterization confirmed effective biofilm formation and electron transfer, while microbial community analysis identified Geobacter sulfurreducens and Pseudomonas aeruginosa as dominant exoelectrogenic species. These results demonstrate that MFC technology powered by tempeh wastewater offers a promising green approach for simultaneous wastewater treatment and energy recovery in food processing industries.

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