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Journal of Biomedical Sciences and Health
Published by Universitas Karya Husada Semarang
ISSN : 30626854     EISSN : 30477182     DOI : https://doi.org/10.34310/
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health
The Journal of Biomedical Sciences and Health (JBSH) accepts manuscripts in basic sciences and applied clinical research. It covers various fields of biomedical sciences, but is not limited to Medical sciences. Our journal accepts and publishes original articles and review articles that significantly contribute to the understanding of biomedical sciences and health. The Journal of Biomedical Sciences and Health is published biannually in the months of February and August. This journal is available for download to anyone, including students, researchers, and lecturers. Authors are not charged for publication in JBSH. JBSH is a journal that disseminates, discusses, and presents scientific literature to support other communities on health developments, thereby increasing the knowledge of scientists and health workers and ultimately improving the health of the global population. JBSH covers a wide range of topics, including: 1. Biomedical Sciences: Molecular biology, microbiology, anatomy, physiology, biochemistry, etc. 2. Health: Medicine, Nursing, Obstetrics, Public Health, Pharmacy, Radiology, Administration of Community Health Centers, Hospitals, and Health Services, Health analyst. Journal of Biomedical Sciences and Health (JBSH) is published by Program Studi Ilmu Biomedis Fakultas Ilmu Keperawatan dan Kesehatan Universitas Karya Husada Semarang. JBSH is expected to increase its visibility through scientific studies and research findings accessible to academic circles and researchers.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol. 1 No. 1 (2024)" : 5 Documents clear
The Potential of Ethanol Extract from Langsat Leaves (Lansium Domesticum Var. Pubescent) In Controlling Aedes Aegypti Mosquitoes: A Study on The Effectiveness of Natural Substances as Mosquito Repellents Ukratalo, Abdul M; Ichsan, Muhammad Nurhidayat; Kaihena, Martha; Manery, Dodikrisno Ekaputra; Pangemanan, Victory Osvaldo; Moniharapon, Debby Dijola
Journal of Biomedical Sciences and Health Vol. 1 No. 1 (2024)
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/jbsh.v1.i1.1

Abstract

In recent decades, attention to the utilisation of natural materials as alternatives in vector control has increased. One potential source that needs to be explored is langsat leaves, which are known to have active compounds. Ethanol extracts of langsat leaves may contain compounds that can provide control effects against Aedes aegypti mosquito larvae. This study aims to assess the effectiveness of the ethanol extract of langsat leaves in controlling Aedes aegypti mosquitoes, the vector of Dengue Fever disease. The extraction method was carried out using the maceration technique with ethanol as the solvent. Bioactivity test was conducted through larvicidal bioassay against Aedes aegypti larvae. The results showed that the ethanol extract of langsat leaves has a larvicidal effect against Aedes aegypti mosquito larvae. The toxicity levels, both LC50 and LC90, indicate that the ethanol extract of langsat leaves has potential as a mosquito larva control agent.
Reproductive Health Optimization: Remarkable Benefits of Avocado Juice (Persea americana P. Mill) in Enhancing Production and Reducing Spermatozoal Abnormalities in Mice Exposed to Clove Cigarette Smoke Kaihena, Martha; Ukratalo, Abdul M; Pangemanan, Victory O; Manery, Dodikrisno E
Journal of Biomedical Sciences and Health Vol. 1 No. 1 (2024)
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/jbsh.v1.i1.2

Abstract

Background: Cigarette smoke has the potential to disrupt hormonal balance, affect spermatogenesis processes, damage spermatozoa viability, and create the presence of toxic substances in spermatozoa. On the other hand, avocados contain protein and various vitamins, such as A, B, B1, B2, E, and C, as well as other substances, such as beta-carotene, linoleic acid, lecithin, calcium, iron, pantothenic acid, potassium, phosphorus, niacin, and natural plant oils. Vitamins C and E in avocados are believed to increase the number of Leydig cells and spermatozoa. Objective: This study aims to evaluate the potential of avocado juice to improve reproductive health in mice exposed to kretek cigarette smoke. Methods: Male mice (Mus musculus) aged 2 months, weighing ±20g each, were divided into 5 randomly assigned groups: K- (control without treatment), K+ (positive control exposed to cigarette smoke), P1 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.5 ml/20 g BW), P2 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.7 ml/20 g BW), and P3 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.9 ml/20 g BW). Cigarette smoke exposure was conducted for 14 days. Results: The results showed that regular avocado juice consumption could increase sperm production and reduce spermatozoa abnormalities in mice exposed to kretek cigarette smoke. Conclusion: The clinical implications of these findings may contribute to a better understanding of avocado juice's potential as a supplement to improve reproductive health, especially in the context of kretek cigarette smoke exposure.
Ethnobotany and Potential of Suruhan (Peperomia pellucida) as a Herbal Medicine Ingredient Rovik, Anwar; Uly Andyra, Vania; Afifah, Laelatul; Rokhmalia, Nur
Journal of Biomedical Sciences and Health Vol. 1 No. 1 (2024)
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/jbsh.v1.i1.3

Abstract

People have long used various herbs for traditional medicine. One of the medicinal plants used by local people is suruhan or sirih cina (Peperomia pellucida). Peperomia pellucida has many local names, such as suruhan, sirih cina, rumput cacing, sirih bumi, pansit-pansitan, rumput gelas, and daing siheah cino. Suruhan plants are used in traditional medicine in various ways, depending on the type of disease. The most widely used part of the plant is the leaves. Suruhan contains many bioactive compounds, such as alkaloids, flavonoids, sterols, tannins, reducing sugars, amino acids, saponins, triterpenoids, carbohydrates, phenols, azulene, carotenoids, and quinones. Suruhan has the potential as an herbal medicinal, including antimicrobe, anticancer, and antifungal.
The Effect of Boiled Water Concentration of Red Betel Leaf (Piper crocatum) on the Kidney and Pancreas Histopathology of Diabetic Mice (Mus musculus) Surati; Dessy Armalina; Erika Wahyuningrum; Deva Alfira Cahayaning; Poppy Fransisca A
Journal of Biomedical Sciences and Health Vol. 1 No. 1 (2024)
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/jbsh.v1.i1.6

Abstract

Abstrak Kandungan yang dimiliki daun sirih merah adalah senyawa flavonoid yang baik untuk menurunkan kadar gula darah. Senyawa flavonoid bersifat antioksidan yang dapat meminimalisasi kerusakan jaringan dengan cara menurunkan peroksida lipid. Penelitian ini bertujuan untuk mengetahui adanya efek hasil rebusan dari daun sirih merah dengan konsentrasi 25%, 50%, 75n 100% terhadap histopatologi ginjal dan pankreas mencit diabetes dan mengetahui konsentrasi yang efektif. Metode yang digunakan merupakan jenis penelitian eksperimental dengan desain Rancangan Acak Lengkap (RAL) dengan 2 kelompok kontrol yaitu K+ dan K-, dan 4 kelompok perlakuan yaitu P1, P2, P3 dan P4, dengan populasi sampel sebanyak 18 ekor mencit yang dibuat preparat histopatologi ginjaldan pankreasnya dan diamati dengan mikroskop perbesaran 400x dan ulangan 3 lapang pandang. Hasil penelitian dilakukan uji statistik MANOVA (Multivariate Analisys Of Variable). Hewan coba ditretmen dengan pemberian sonde rebusan daun sirih merah dengan konsentrasi 25%, 50%, 75n 100ngan dosis 50 mg dan dosis sonde 0,13 ml kepada mencit diabetes menunjukkan gambaran mikroskopis sel yang mengalami perbaikan. Hasil pengamatan histopatologi pankreas dilakukan uji statistik menggunakan Kruskal Wallis dilanjutkan uji Mann Whitney menunjukkan nilai sig. 0,015 dimana nilai tersebut .   Kata Kunci: Diabetes, daun sirih merah, ginjal, pankreas. Abstract The content of red betel leaves is flavonoid compounds which are good for lowering blood sugar levels. Flavonoid compounds have antioxidant properties that can minimize tissue damage by reducing lipid peroxidation. This study aims to determine the effect of boiled red betel leaves with concentrations of 25%, 50%, and 75n 100% on the histopathology of the kidneys and pancreas of diabetic mice and to determine the effective concentration. The method used is a type of experimental research with a Completely Randomized Design (CRD) with 2 control groups, namely K+ and K-, and 4 treatment groups, namely P1, P2, P3, and P4, with a sample population of 18 mice for which kidney histopathology preparations were made and pancreas and observed with a microscope with 400x magnification and repeated 3 fields of view. The results of the research were carried out by MANOVA (Multivariate Analysis of Variables) statistical tests. Experimental animals were treated by administering a sonde of boiled red betel leaves with a concentration of 25%, 50%, 75n 100 with a dose of 50 mg, and a sonde dose of 0.13 ml to diabetic mice showing a microscopic picture of the cells experiencing improvement. The results of pancreatic histopathological observations were carried out through statistical tests using Kruskal Wallis followed by the Mann-Whitney test showing a sig value. 0.015 where the value is. Keywords: Diabetes; kidney;  pancreas; red betel leaf.
PROVIDING KB EDUCATIONAL INFORMATION COMMUNICATION (KIE) USING LEAFLET MEDIA IN DECISION-MAKING ON IUD CONTRACEPTION DEVICES Meika Jaya Rochkmana; Rohayati; Mariza Mustika Dewi
Journal of Biomedical Sciences and Health Vol. 1 No. 1 (2024)
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/jbsh.v1.i1.30

Abstract

Kebijakan pemerintah dalam bidang kependudukan, memiliki implikasi yang tinggi terhadap pembangunan kesehatan, oleh karena itu program KB memiliki posisi strategis dalam upaya pengendalian laju pertumbuhan penduduk. Secara umum faktor-faktor yang menyebabkan PUS tidak menjadi peserta KB adalah pelayanan KB yang masih kurang berkualitas, keterbatasan alat  kontrasepsi,  penyampaian informasi media leaflet maupun KIE serta minimnya informasi yang didapat oleh PUS untuk mendapatkan informasi dalam pengambilan keputusan. Tujuan Penelitian ini adalah untuk mengetahui pengaruh pemberian KIE KB dengan Media Leaflet dalam pengambilan keputusan alat kontrasepsi IUD. Metode Penelitian menggunakan rancangan pra eksperimen dengan posttest only design. Populasi di Puskesmas Gunungpati Semarang sebanyak 1648, sampel 50 diambil dengan proportional cluster random sampling. Data dianalisis dengan uji Independen T Test dengan hasil sig 0.002 < 0,05 Hasil penelitian ada pengaruh pemberian KIE KB dengan media leaflet dalam pengambilan keputusan alat kontrasepsi IUD dengan hasil sig < 0,05 dan ada perbedaan pemberian KIE KB dengan media leaflet dalam pengambilan keputusan alat kontrasepsi IUD dengan hasil sig < 0,05 Kesimpulan bahwa KIE dengan media leaflet efektif untuk meningkatkan kemantapan dalam pengambilan keputusan alat kontrasepsi MKJP IUD pada PUS. Disarankan agar petugas kesehatan tetap memberikan KIE kepada PUS untuk meningkatkan kemantapannya dalam pengambilan keputusan alat kontrasepsi IUD.   Katakunci:  KIE, media leaflet, Pengambilan Keputusan, IUD

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